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Wednesday, 22 November

22:00

US Court issues injunction against OMICS to stop deceptive practices "IndyWatch Feed Health"

A US government agency has won an initial court ruling against OMICS, which the government says will help stop the academic publishers deceptive business practices. Today, the Federal Trade Commission (FTC) announced that it won a preliminary injunction in September in its lawsuit against Srinubabu Gedela, CEO of OMICS Group and other companies. The lawsuit, []

The post US Court issues injunction against OMICS to stop deceptive practices appeared first on Retraction Watch.

21:46

Facebook May be Using Cell Phones to Listen to Private Conversations "IndyWatch Feed Health"

Facebook is known for bringing people together. It can help you to stay connected with friends and family, find your long-lost high school crush, or keep you entertained for hours with videos of baby animals. But, perhaps thats not all they do. A husband and wife suspected that Facebook was listening in on their private... View Article

The post Facebook May be Using Cell Phones to Listen to Private Conversations appeared first on Healthy Holistic Living.

21:28

This provides support for both the acceptability and the effectiveness of treatment by a homeopath for patients with self-reported depression. "IndyWatch Feed Health"

PMID:  Trials. 2017 Jun 30 ;18(1):299. Epub 2017 Jun 30. PMID: 28666463 Abstract Title:  Depressed patients treated by homeopaths: a randomised controlled trial using the"cohort multiple randomised controlled trial"(cmRCT) design. Abstract:  BACKGROUND: Despite controversy regarding homeopathy, some patients consult homeopaths for depression. Evidence is required to determine whether this is an effective, acceptable and safe intervention for these patients.METHODS: A pragmatic trial using the"cohort multiple randomised controlled trial"design was used to test the effectiveness of adjunctive treatment by homeopaths compared to usual care alone, over a period of 12 months in patients with self-reported depression. One third of patients were randomly selected for an offer of treatment provided by a homeopath. The primary outcome measure was the Patient Health Questionnaire (PHQ-9) at 6 months. Secondary outcomes included depression scores at 12 months; andthe Generalised Anxiety Disorder (GAD-7) outcome at 6 and 12 months.RESULTS: The trial over-recruited by 17% with a total of 566 patients. Forty percent took up the offer and received treatment. An intention-to-treat analysis of the offer group at 6 months reported a 1.4-point lower mean depression score than the no offer group (95% CI 0.2, 2.5, p=0.019), with a small standardized treatment effect size (d=0.30). Using instrumental variables analysis, a moderate treatment effect size in favour of those treated was found (d=0.57) with a between group difference of 2.6 points (95% CI 0.5, 4.7, p=0.018). Results were maintained at 12 months. Secondary analyses showed similar results. Similar results were found for anxiety (GAD-7). No evidence suggested any important risk involved with the intervention.CONCLUSION: This trial provides preliminary support for both the acceptability and the effectiveness of treatment by a homeopath for patients with self-reported depression. Our results provide support for further pragmatic research to provide more precise estimates of treatment effect.TRIAL REGISTRATION: ISRCTN registry, ISRCTN02484593 . Registered on 7 January 2013.

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21:16

M1 complex can be a good candidate for a complementary therapy to conventional treatments for leishmaniasis. "IndyWatch Feed Health"

PMID:  Cytokine. 2017 Nov ;99:80-90. Epub 2017 Jul 23. PMID: 28738234 Abstract Title:  M1 homeopathic complex trigger effective responses against Leishmania (L) amazonensis in vivo and in vitro. Abstract:  Leishmaniasis is a term referring to a range of clinical conditions caused by protozoan parasites of the genus Leishmania, Trypanosomatidae family, Kinetoplastida order that is transmitted by the bite of certain species of mosquitoes Phlebotominae subfamily. These parasites infect hosts wild and domestic mammals, considered as natural reservoirs and can also infect humans. Leishmania are obligate intramacrophage protozoa that have exclusively intracellular life style. This suggests that the amastigotes possess mechanisms to avoid killing by host cells. Cutaneous leishmaniasis, the most common form of the disease, causes ulcers on exposed parts of the body, leading to disfigurement, permanent scars, and stigma and in some cases disability. Many studies concluded that the cytokines profile and immune system of host have fundamental role in humans and animals natural self-healing. Conventional treatments are far from ideals and the search for new therapeutic alternatives is considered a strategic priority line of research by the World Health Organization. A promising approach in the field of basic research in homeopathy is the treatment of experimental infections with homeopathic drugs prepared from natural substances associations highly diluted, which comprise a combination of several different compounds considered as useful for a symptom or disease. Therefore, this study aimed to evaluate the effect of M1, a complex homeopathic product, in macrophage-Leishmania interaction in vitro and in vivo. It was used RAW cells lineage and BALB/c mice as a host for the promastigotes of L. amazonensis (WHOM/BR/75/Josefa). Several biochemical and morphological parameters were determined. Together, the harmonic results obtained in this study indicate that, in general, the highly diluted products trigger rapid and effective responses by living organisms, cells and mice, against Leishmania, by altering cytokines profile, by NO increasing (p

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21:02

Homeopathic bowel nosodes are a useful method for controlling gastrointestinal disturbances. "IndyWatch Feed Health"

PMID:  J Altern Complement Med. 2017 Aug 14. Epub 2017 Aug 14. PMID: 28805460 Abstract Title:  Case Study of Homeopathic Bowel Nosode Remedies for Dysbiotic Japanese Patients. Abstract:  BACKGROUND: The composition of intestinal microbiota is very important in human health. Gastrointestinal disturbances are among the symptoms commonly reported by individuals diagnosed with chronic diseases, such as inflammatory bowel disease, autism, and chronic fatigue syndrome. The effects of probiotics and prebiotics for dysbiosis have been reported in many studies. Bowel nosodes are homeopathic remedies made from human gut microbiota.OBJECTIVE: Bowel nosodes made from the intestinal bacteria of European patients from the 1900s were administered to Japanese patients suffering from gastrointestinal disturbances, such as constipation and diarrhea, to determine their therapeutic efficacy.METHODS: Twenty-eight outpatients from Yoko Clinic (11 males, 17 females; age range, 4-72 years) were enrolled in this study. One nosode remedy was selected for each case. Patients took six pills for 2 days. After a month, the effect of each treatment was evaluated using the Glasgow Homeopathic Hospital Outcome Scale (grade +4 to -4).RESULTS: Patient number of each grade was +4 (N=2), +3 (N=4), +2 (N=7), +1 (N=3), 0 (N=7), with no negative grades. Of the 23 patients analyzed, 69.6% showed some type of improvement, and no harmful effects from taking bowel nosodes were observed; 26% of patients showed major improvement or were"cured."CONCLUSION: It is difficult to find correct constitutional remedies as they often require high-level techniques and time. Since there are only 11 main bowel nosode remedies, they are easier to choose from and cheaper to use and develop than classical constitutional remedies. Herein, 69.6% of dysbiotic patients taking bowel nosodes showed improvements, and no harmful effects were reported by any patient. These results suggest that the homeopathic bowel nosodes are a useful method for controlling gastrointestinal disturbances.

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20:44

Homeopathic medicines can alleviate the intensity or reduce the duration of whooping cough. "IndyWatch Feed Health"

PMID:  Altern Ther Health Med. 2017 Oct 2. Epub 2017 Oct 2. PMID: 28987075 Abstract Title:  Whooping Cough Alleviated by Homeopathic Medicines: A Case Report. Abstract:  Context Pertussis cough (whooping cough) is distressing due to the intensity and chronicity of its cough. No specific drugs are available that can alleviate the cough's intensity or significantly shorten its duration. Homeopathic medicines are used for a wide variety of medical conditions, including cough. Objective The study investigated the benefits of homeopathic medicines for whooping cough, to alleviate the cough's intensity and to shorten its duration. Design The current study was a case series of patients with whooping cough. Setting The study took place at one of the suburban hospital clinics of the Ann&Robert H. Lurie Children's Hospital of Chicago (Chicago, IL, USA). Participants Participants were 20 patients aged 21 mo to 20 y, of whom 11 were female and 18 were male, who visited the hospital clinic for treatment of the chronic cough that is characteristic of whooping cough. The details of the cases of 3 representative participants are highlighted in the text. Intervention The 3 representative patients all received 1 dose weekly of a 30c dilution of homeopathic pertussinum and a 6c dilution of homeopathic Drosera 3 times daily. The homeopathic medicines most often used for the other participants were the same doses of pertussinum and Drosera. Outcome Measures Verbal feedback from patient or family were obtained at the follow-up visits. Results The intensity and duration of participant's coughs were alleviated within days to 1 wk in most cases. Conclusions Homeopathic medicines can alleviate the intensity or reduce the duration of whooping cough, with no adverse effects.

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20:33

Researchers Warn How Pesticides Are Secretly Growing Antibiotic Resistance "IndyWatch Feed Health"

By Heather CallaghanEditor

More emphasis needs to be placed on antibiotic stewardshipOtherwise, new drugs will fail rapidly and be lost to humanity.

The first team of researchers ever to discover that the worlds most popular pesticides and herbicides increase the antibiotic resistance crisis have conducted another study to prove once and for all a frightening truth we must respond to.

Researchers at the University of Canterbury in New Zealand have confirmed once again that  active ingredients of the commonly used herbicides, Roundup, Kamba and 2,4-D (glyphosate, dicamba and 2,4-D, respectively), each alone cause antibiotic resistance at concentrations well below label application rates.

GMWatch reports:

Professor Jack Heinemann of the School of Biological Sciences in UCs College of Science said the key finding of the research was that bacteria respond to exposure to the herbicides by changing how susceptible they are to antibiotics used in human and animal medicine.

The herbicides studied are three of the most widely used in the world, Prof Heinemann said. They are also used on crops that have been genetically modified to tolerate them.

The effect was n...

19:56

The 2 current case reports demonstrate a successful integrative approach to the treatment of schizoaffective disorder. "IndyWatch Feed Health"

PMID:  Altern Ther Health Med. 2017 Oct 2. Epub 2017 Oct 2. PMID: 28987077 Abstract Title:  Remission of Schizoaffective Disorder Using Homeopathic Medicine: 2 Case Reports. Abstract:  Context Research on the schizophrenia spectrum is primarily focused on pharmaceutical interventions, although alternative treatments have been gaining increasing popularity in recent years because patients are seeking treatments that are effective and have reduced side effects. A significant body of evidence already exists supporting the effectiveness of homeopathy to treat a wide array of illnesses. Objective The research team intended to demonstrate the need for using both alternative and conventional treatments to improve clinical outcomes in the treatment of schizoaffective disorder. Design The research team performed 2 case studies. Setting The study took place at Arizona Natural Health Center (Tempe, AZ, USA), an outpatient clinic where Dr Tara Peyman worked as a naturopathic doctor from 2008 to 2014. Participants The participants were a 23-y-old female (case 1) and a 34-y-old female (case 2), both of whom had been diagnosed with schizoaffective disorder of the bipolar type. Intervention Individualized homeopathic treatment was initiated for the 2 patients, who previously had received medication of atypical antipsychotics and mood stabilizers. Outcome Measures A Likert scale was used to evaluate the intensity of each patient's symptoms at each follow-up, based on self-reporting, using a scale from 1 to 10, with a score of 10 being the highest. Results During the course of treatment, both patients' symptoms normalized, and they regained their ability to hold jobs, attend school, and maintain healthy relationships with their families and partners while requiring fewer pharmaceutical interventions. Conclusions The 2 current case reports demonstrate a successful integrative approach to the treatment of schizoaffective disorder. They illustrate the value of individualized homeopathic prescriptions with proper case management in the successful treatment of that disorder. Future large-scale, double-blind, placebo-controlled studies should investigate individualized homeopathic treatments for mental health concerns, because the diseases cause great economic and social burden.

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19:51

Harvard Immunologist to Legislators: Unvaccinated Children Pose ZERO Risk to Anyone "IndyWatch Feed Health"

Dr Tetyana Obukhanych

Dr. Tetyana Obukhanych

Harvard Immunologist: Unvaccinated Children Pose ZERO Risk to Anyone and Heres Why

Dear Legislator:

My name is Tetyana Obukhanych. I hold a PhD in Immunology. I am writing this letter in the hope that it will correct several common misperceptions about vaccines in order to help you formulate a fair and balanced understanding that is supported by accepted vaccine theory and new scientific findings.

Do unvaccinated children pose a higher threat to the public than the vaccinated?

It is often stated that those who choose not to vaccinate their children for reasons of conscience endanger the rest of the public, and this is the rationale behind most of the legislation to end vaccine exemptions currently being considered by federal and state legislators country-wide.

You should be aware that the nature of protection afforded by many modern vaccines and that includes most of the vaccines recommended by the CDC for children is not consistent with such a statement.

I have outlined below the recommended vaccines that cannot prevent transmission of disease either because they are not designed to prevent the transmission of infection (rather, they are intended to prevent disease symptoms), or because they are for non-communicable diseases.

People who have not received the vaccines mentioned below pose no higher threat to the general public than those who have, implying that discrimination against non-immunized children in a public school setting may not be warranted.

Polio Vaccine

IPV (inactivated poliovirus vaccine) cannot prevent transmission of poliovirus. Wild poliovirus has been non-existent in the USA for at least two decades.

Even if wild poliovirus were to be re-imported by travel, vaccinating for polio with IPV cannot affect the safety of public spaces.

Please note that wild poliovirus eradication is attributed to the use of a different vaccine, OPV or oral poliovirus vaccine. Despite being capable of preventing wild poliovirus transmission, use of OPV was phased out long ago in the USA and replaced with IPV due to safety concerns...

19:51

Homeopathy can be successfully incorporated within a supportive care integrative oncology service. "IndyWatch Feed Health"

PMID:  Integr Cancer Ther. 2017 Oct 1:1534735417736133. Epub 2017 Oct 1. PMID: 29094627 Abstract Title:  Feasibility of Homeopathic Treatment for Symptom Reduction in an Integrative Oncology Service. Abstract:  BACKGROUND: Homeopathy has the potential to reduce symptoms related to cancer treatment. The present study examined the feasibility of a homeopathic consultation and treatment program, provided as part of an integrative oncology service.METHODS: The electronic medical files of patients undergoing a homeopathic consultation in an integrative oncology service clinic were examined retrospectively. Adherence to the homeopathic treatment regimen and perceived response to the treatment were evaluated.RESULTS: The files of 124 patient (34 males, 90 females) were examined, of which two-thirds reported acquiring and self-administering the homeopathic remedy as prescribed, and nearly three-quarters reporting a beneficial effect. Adherence to the homeopathic treatment regimen was greatest among patients attending a second visit, as opposed to having only telephone/e-mail follow-up ( P

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19:41

Effectiveness of the homeopathic preparation Zeel compared with carprofen in dogs with osteoarthritis. "IndyWatch Feed Health"

PMID:  J Am Anim Hosp Assoc. 2011 Jan-Feb;47(1):12-20. Epub 2010 Dec 16. PMID: 21164168 Abstract Title:  Effectiveness of the homeopathic preparation Zeel compared with carprofen in dogs with osteoarthritis. Abstract:  The authors compared the symptomatic effectiveness of a complex homeopathic preparation Zeel (1-3 tablets orally per day depending on body weight) to carprofen (4 mg/kg body weight) in dogs (n=68) aged>1 yr diagnosed with osteoarthritis in a multicenter, prospective, observational open-label cohort study in 12 German veterinary clinics. The active treatment period was 56 days. Symptomatic effectiveness, lameness, stiffness of movements, and pain on palpation were evaluated by treating veterinarians and owners. Clinical signs of osteoarthritis improved significantly (P

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19:35

Harvard Immunologist to Legislators: Unvaccinated Children Pose ZERO Risk to Anyone "IndyWatch Feed Health"

Dr Tetyana Obukhanych

Dr. Tetyana Obukhanych

Harvard Immunologist: Unvaccinated Children Pose ZERO Risk to Anyone and Heres Why

Dear Legislator:

My name is Tetyana Obukhanych. I hold a PhD in Immunology. I am writing this letter in the hope that it will correct several common misperceptions about vaccines in order to help you formulate a fair and balanced understanding that is supported by accepted vaccine theory and new scientific findings.

Do unvaccinated children pose a higher threat to the public than the vaccinated?

It is often stated that those who choose not to vaccinate their children for reasons of conscience endanger the rest of the public, and this is the rationale behind most of the legislation to end vaccine exemptions currently being considered by federal and state legislators country-wide.

You should be aware that the nature of protection afforded by many modern vaccines and that includes most of the vaccines recommended by the CDC for children is not consistent with such a statement.

I have outlined below the recommended vaccines that cannot prevent transmission of disease either because they are not designed to prevent the transmission of infection (rather, they are intended to prevent disease symptoms), or because they are for non-communicable diseases.

People who have not received the vaccines mentioned below pose no higher threat to the general public than those who have, implying that discrimination against non-immunized children in a public school setting may not be warranted.

Polio Vaccine

IPV (inactivated poliovirus vaccine) cannot prevent transmission of poliovirus. Wild poliovirus has been non-existent in the USA for at least two decades.

Even if wild poliovirus were to be re-imported by travel, vaccinating for polio with IPV cannot affect the safety of public spaces.

Please note that wild poliovirus eradication is attributed to the use of a different vaccine, OPV or oral poliovirus vaccine. Despite being capable of preventing wild poliovirus transmission, use of OPV was phased out long ago in the USA and replaced with IPV due to safety concerns....

19:24

Combination treatment with cyclophosphane and its homeopathically potentiated forms increases antiblastic activity of the preparation. "IndyWatch Feed Health"

PMID:  Bull Exp Biol Med. 2003 Jan ;135 Suppl 7:107-10. PMID: 12949669 Abstract Title:  Potentiated cyclophosphane: experimental study of the effect on tumor development and efficiency of cytostatic therapy. Abstract:  Experiments on animals with transplanted tumors (Lewis lung carcinoma and carcinosarcoma Walker-256) showed that combination treatment with cyclophosphane and its homeopathically potentiated forms increases antiblastic activity of the preparation.

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19:17

Reclaiming Ancient Wisdom "IndyWatch Feed Health"

Discussions and articles about vaccines often delve into what science is and what it is not.  Vaccine promoters might accuse vaccine skeptics of being anti-science; of equating the audacity to question the safety and efficacy of vaccines with the theocratic doubting of the roundness or ancientness of the earth.

Vaccine skeptics, in turn, charge pharmaceutical enthusiasts with employing tobacco science; of using the same methods and manipulations the tobacco industry used for decades to prove their products were safe. While the analysis of data is crucial to the conversation, the game of dueling scientific studies can become tiresome. So perhaps we should probe deeper into this concept of science. What is science? How did it begin? And how does it get hijacked?

Science began, and always begins, with careful observation. The first scientists may have been prehistoric mothers who used their attentiveness to solve real problems. Their vigilant discernment enabled them to learn which plants, prepared in what fashion, caused what effects, and cured which ailments. Imagine the vastness of the collective wisdom gathered and held by those early countless generations of mothers.

Endless study and experimentation. This herb heals the skin. That tree bark reduces pain.  They didnt have fresh white coats with pocket protectors and sterile laboratories with beeping equipment. They did, though, possess the awesome power of intuition and the cognitive desire to protect, to heal, and to remember.

Human knowledge did not start from zero in the 17th century. Throughout the Renaissance thousands of women were burned at the stake for the crime of being female.  Sure, much was gained in science and the arts during this time, but what was lost? Women.  The wise, the healers, the leaders, the sacred ones who held those countless generations of carefully accrued knowledge were lost in the flames.

Trust was also methodically destroyed. How could one trust their neighbor when the wrong words could be reported as blasphemy or an innocent question become a fatal rumor of heresy? Trust itself was persecuted. One could no longer speak without fear to a friend in the village square. Revealed secrets of the earth long passed from matriarch to woman to girl ceased to flow.

The most human act of sharing information, of communicating ideas, of learning from each other was shut down. Trust was to be placed only in the Church. Knowledge was to be disseminated only from men to men within the confines of the newly sanctioned universities.

In their conquest of New World, explorers and colonizers annihilated native cultures that had for millennia collected knowledge of the Earth. The Spanish conquistadors in South America crushed into archeological dust countless libraries of clay tablets inscribed w...

19:01

MRI Dye "IndyWatch Feed Health"

Chuck Norris Sues for MRI Dye Injuring His Wife

  • 1.6K 
  • November 22, 2017 18,489 views





Story at-a-glance
  • Magnetic resonance imaging (MRI) is a study allowing your physician to see detailed images of your organs and tissues using a large magnet and radio waves
  • Gadolinium-based contrast agents (GBCAs) may be prescribed to enhance the image but the heavy metal gadolinium is known to deposit in your brain, bone and organs
  • The FDA acknowledges the metal may be found in your tissues for years but claims there is no known effect, despite the rising number of people suffering from kidney damage, cognitive dysfunction and muscle wasting
  • Strategies you may consider if an enhanced MRI is absolutely necessary include optimizing your gut and nutrition, eating fermented foods and using a sauna to aid detoxification
By Dr. Mercola
Magnetic resonance imaging (MRI) is an imaging study that allows your physician to see detailed pictures of your organs and tissues. Raymond Damadian invented the machine and performed the first total body image in 1977.1 This process has been called the one of the greatest medical breakthroughs of the 20th century.
The MRI machine uses a large magnet, radio waves and a computer to take detailed cross-sectional pictures of your internal organs and tissues.2 The scanner looks like a tube with a table that enables you to slide into the tunnel of the machine to gather data. Unlike CT scans or X-rays that use ionizing radiation known to damage...

18:54

Editorial board of public health journal resigns in protest "IndyWatch Feed Health"

The editorial board of the International Journal of Occupational and Environmental Health resigned today in protest over ongoing battles involving the new editor and its handling of recent withdrawals. Weve covered the boards gripes with the journal and publisher, which date back to the spring, and include appointing a new editor with industry ties without []

The post Editorial board of public health journal resigns in protest appeared first on Retraction Watch.

18:54

Brain Regeneration Can Infrared Light Reverse Parkinson's and Alzheimer's? "IndyWatch Feed Health"

Brain Regeneration: Can Infrared Light Reverse Parkinsons and Alzheimers?

Posted on: Tuesday, November 21st 2017 at 12:30 pm
This article is copyrighted by GreenMedInfo LLC, 2017

Contrary to conventional wisdom, brain regeneration is possible. One promising therapy that promotes neurogenesis and is effective in pre-clinical studies of Alzheimers and Parkinsons is near infrared light therapy, and it may improve other mental illnesses and neurodegenerative disorders including dementia, stroke, ALS, and traumatic brain injury as well.
Alzheimers disease and Parkinsons disease are the most common neurodegenerative disorders. The former is a type of dementia that occurs secondary to the accumulation of abnormal protein deposits in the brain, including -amyloid plaques and intraneuronal neurofibrillary tangles made of tau protein (1). Upon neuroimaging studies, gross cerebral cortical atrophy is found, meaning that the part of the brain responsible for executive functions such as learning, memory, language, decision-making, and problem-solving progressively degenerates (1). In addition, gliosis, or brain inflammation, is a hallmark characteristic of Alzheimers (1).
One hypothesis that is championed proposes that Alzheimers occurs due to self-propagating, prion-like protein assemblies, which interfere with the function of nerve cells (2). An alternate theory is that these so-called proteinopathies occur secondary to a microvascular hemorrhage or brain bleed (3). The brain bleed is believed to be the result of age-induced degradation of cerebral capillaries, which creates neuron-killing protein plaques and tangles (3).
Dysfunction of mitochondria, the energy-generating powerhouses of the cell, is also implicated in Alzheimers, as reduced efficacy of these organelles creates oxidative stress-inducing reactive oxygen species, or free radicals, which lead to neuronal cell death (4). Whatever the cause, extensive death of brain cells occurs, which explains the cognitive deficits that occur with Alzheimers disease, in add...

18:52

Soon Big Brother Will Know If You Took Your Medicine "IndyWatch Feed Health"

This opens the door to all kinds of scary possibilities.

From ABC News:

In a groundbreaking decision on Monday, the Food and Drug Administration approved a drug with a digital ingestion tracking system, which senses when a pill is swallowed and sends the data to a smartphone.

The new drug/device combination product called Abilify MyCite is approved for the treatment of schizophrenia and mood disorders. The Abilify (aripiprazole) tablets come embedded with an Ingestible Event Marker (IEM) sensor, the size of a grain of sand, that sends information to a patch the patient wears. The patch then transmits the data to smartphones and online healthcare portals which can be accessed by health care professionals and caregivers if the patient approves.

Comment: Aside from the creepy invasion of privacy and other opportunities for abuse with this technology, lets not forget the dangers of electromagnetic fields and Wi-Fi, especially for young children. Cell phones, for instance, include warnings in the fine print about overexposure. And what are the potential health consequences of ingesting a digital ingestion tracking system? Orwellian medicine, coming soon unless we object! By the way, here are the possible side effects of Abilify.

 

 

18:48

Medical Vaccine Exemption Under Renewed Fire "IndyWatch Feed Health"

For some in California, doctors writing medical exemptions from the states draconian vaccination law are not being punished swiftly enough.

From the LA Times:

A year ago, California officials appeared to be coming down hard on doctors and parents who were reluctant to vaccinate children. The medical board was threatening to pull the license of Dr. Robert Sears, a celebrity in the anti-vaccine community.

But so far, no doctors, including Sears, have been punished for writing unnecessary medical exemptions. The crackdown many foresaw never materialized.

Comment: The LA Times article may in part be a reaction to the recent announcement that Dr. Bob Sears, who faces charges of gross negligence from the California medical board, has a hearing scheduled for May 2018. As Richard Jaffee, Dr. Searss attorney, notes, perhaps May 2018 isnt soon or severe enough for the LA Times.

What are the allegations against Dr. Sears? He dared to write a letter recommending that a two-year-old be excused from vaccinations because his mother reported that the child had serious adverse reactions to previous immunizations. We pointed out before that the goal of such persecution is to scare other doctors from writing medical exemptions. Are the LA Times reporters qualified medical professionals, equipped with the knowledge of when a medical exemption is necessary? We suspect not, but this is how low the conversation has gone on the issue of vaccinationpersecuting a doctor for exercising his judgment.

18:21

Chuck Norris Sues 11 Drug Companies for Poisoning His Wife "IndyWatch Feed Health"

Source: Chuck Norris Sues 11 Drug Companies for Poisoning His Wife For more content like this visit REALfarmacy.com.

By Tracey Watson Most of us are familiar with the actor Chuck Norris, hero of action shows and movies like Walker Texas Ranger and Martial Law. Norris is famous for taking on the baddies and always winning. Now, he may have taken on the biggest fight of his life. The Daily Mail recently reported that Norris []

Source: Chuck Norris Sues 11 Drug Companies for Poisoning His Wife Learn more at REALfarmacy.com - Healthy News and Information.

17:56

FDA Attacks CBD Supplements to Protect Big Pharmas Profits "IndyWatch Feed Health"

Source: FDA Attacks CBD Supplements to Protect Big Pharmas Profits For more content like this visit REALfarmacy.com.

Big Pharma is working overtime to restrict consumer access to cannabidiol, or CBD, a non-psychoactive component of cannabis sativa (marijuana) that has been shown to help relieve pain, muscle spasms, and other ailments. Using the U.S. Food and Drug Administration (FDA) as authoritative cover, the industry is quietly leading the charge to ban CBD from []

Source: FDA Attacks CBD Supplements to Protect Big Pharmas Profits Learn more at REALfarmacy.com - Healthy News and Information.

17:45

Gene Editing vs. Alternative Technology "IndyWatch Feed Health"

By Brian Berletic

Ed Yong in his article, New Zealands War on Rats Could Change the World, helped frame an ongoing debate over using genetically modified organisms (GMOs) altered through gene-editing technology to eradicate pests. In this particular case, the problem is rats and other invasive predatory mammals that endanger New Zealands native bird populations.

Yong covers proposals to introduce genes into mammalian populations to hinder their ability to reproduce. These gene-drives are unlike other technologies like gene therapy, which replace faulty genes in human patients to correct genetic diseases or enhance an individual...

17:40

$55 Million in Cocaine Discovered at a Coca-Cola Plant "IndyWatch Feed Health"

Source: $55 Million in Cocaine Discovered at a Coca-Cola Plant For more content like this visit REALfarmacy.com.

Hundreds of kilos of cocaine were found in a Coca-Cola plant in France, making the seizure of the drug one of the largest ever on French soil. French officials say the cocaine was discovered in backpacks among a shipment of orange juice concentrate that originated in Costa Rica. The 370 kg of literal coke uncovered at the []

Source: $55 Million in Cocaine Discovered at a Coca-Cola Plant Learn more at REALfarmacy.com - Healthy News and Information.

17:37

To fluoridate or not to fluoridate? Edgartown board of health leaves it up to voters. "IndyWatch Feed Health"

The Edgartown board of health stood by its controversial decision to add fluoride to the municipal water system despite heated debate at a meeting Tuesday evening called to review the boards earlier action.

At Tuesdays meeting, with 15 people in the audience, the board held firm knowing that enough signatures had been gathered by petition to bring the question of adding fluoride to the water to town voters.

Wed like to start out by apologizing to the water department, board of health member Harold Zadeh said. You should have been involved from the start. We found out Wednesday that there are 400 names on the petition, so it will be put on a ballot. That was our intent anyways.

At issue is the Oct. 10 vote by Mr. Zadeh and Dr. Garrett Orazem to enact a statute that would fluoridate the towns water supply. Board member Kathie Case abstained from the vote. Residents were given 90 days from the date the community was notified to gather signatures from 10 percent of the towns 3,628 registered voters.

The announcement was published on Oct. 20, enraging some in the community and prompting a petition drive thats gathered enough signatures to get the issue before voters at a spring town meeting.

So youre not going to rescind? Edgartown resident and harbormaster Charlie Blair said from the audience.

Im not going to rescind, Im going to let it go through the process, Mr. Zadeh responded, and Mr. Blair abruptly left the meeting.

After nearly an hour of discussion, the board officially decided not to rescind and instead will attempt to educate voters leading up to town meeting, Mr. Zadeh said.

Once again, Ms. Case was not at the meeting. She was off-Island at an appointment.

Were not going to agree on this, health agent Matt Poole said. But I think we should talk about what happens if this does pass. The meeting concluded, and transparency was mentioned a key to collaboration moving forward.

Not everyone at the meeting was opposed to fluoride in the water. Chilmark resident and Vineyard Haven dentist Bruce Golden spoke to the boards decision, stating that two-thirds of the nations population drinks fluoridated water. Fluoridated water is a wonderful, reasonable, healthy, and inexpensive thing, he said.

For some, the key issue was the process used by the board. At a meeting last week, members of the water commission said the decision shouldnt have been made without their input, as well as feedback from the community at large.

I dont think anybody, local or federal, should dictate what entire communities take for medication, water superintendent Bi...

14:34

WATCH: Doctor Wants You To Rethink Vaccines "IndyWatch Feed Health"

Dr. Eric Berg wants to talk to you about vaccines, however, as he makes clear in the video, he doesnt want to talk at you. Dr. Berg states I am not telling you to take...

The post WATCH: Doctor Wants You To Rethink Vaccines appeared first on Vaxxter.

14:31

The Surprising Reason Why Every Home Should Have At Least One Himalayan Salt Lamp (Plus How Many to Put In Each Room for Maximum Benefits) "IndyWatch Feed Health"

 

himalayan salt lamps health benefits

Himalayan salt lamps offer a multitude of health benefits due to the negative ions they emit. Click the picture for more info.

 

 

 

14:00

Caught Our Notice: Waitwe wrote WHAT paper? "IndyWatch Feed Health"

Title: Assessment of coronary heart diseases in diabetics in al-Madinah al-Munawarah What Caught Our Notice: Weve seen researchers dinged for adding authors to papers who didnt participate in the research, but its rare to have a notice say co-author signatures were forged. In a recent retraction, the first two authors said the signatures on the the []

The post Caught Our Notice: Waitwe wrote WHAT paper? appeared first on Retraction Watch.

13:46

HERBESO REMEDIES FOR THE BEST DMSO THERAPY "IndyWatch Feed Health"

NATURES HEALER DMSO is the newest twenty-first centurys healing drug with a very wide range of health benefits, acting as a holistic ingredient which brings whole body cellular functions back to normal. It has a battered thirty years history sowing miraculous examples of healing of many acute and chronic health conditions, sometimes with unbelievable effects.

13:24

New Tools Against Antibiotic Resistance "IndyWatch Feed Health"

Antibiotic resistance is a serious problem that may lead to a post-antibiotic era. However, there are potential solutions that deserve research priority.

12:03

Climate Change Puts Cambodians at Risk of Mental Health Issues "IndyWatch Feed Health"

From Eco-Business: Many Cambodians are still healing from a tragic recent past, from the Lon Nol regime in 1970 to the collapse of the Pol Pot regime in 1979. However, the country is highly vulnerable to climate change, and Cambodians risk experiencing a mental health relapse as a result.

According to a recent research commissioned by the American Psychological Association this year, long-term climate change can indirectly cause mental health problems as the changes in weather patterns, storm and rising sea levels put people in danger of experiencing chronic psychological consequences such as trauma and shock, chronic depression, stress disorder and anxiety.

High levels of stress and anxiety are also linked to physical health effects, such as a weakened immune system, the report explains. Worrying about actual or potential impacts of climate change can lead to stress that can build over time and eventually lead to stress-related problems, such as substance abuse, anxiety disorders and depression.'

Article

12:02

A Likely Culprit for Teen Mental Health Deterioration "IndyWatch Feed Health"

From The Conversation: In the five years between 2010 and 2015, U.S. teens mental health greatly deteriorated. The sudden ascendance of the smartphone is most likely to blame for this increase in teen mental health issues.

Article

12:01

Selling Bad Therapy to Trauma Victims "IndyWatch Feed Health"

From Psychology Today: The American Psychological Association has just issued guidelines for treating trauma that are backed by faulty science. The research behind the guidelines only studied therapies of 16 sessions or less, excluding long-term forms of psychotherapy that may be more effective.

One way that health insurers circumvent parity laws is by shunting patients to the briefest and cheapest therapies just the kind of therapies recommended by the APAs treatment guidelines. Another way is by making therapy so impersonal and dehumanizing that patients drop out. Health insurers do not publicly say the treatment decisions are driven by economic self-interest. They say the treatments are scientifically proven and point to treatment guidelines like those just issued by the APA.

Its bad enough that most Americans dont have adequate mental health coverage, without also being gaslighted and told that inadequate therapy is the best therapy.

Article

12:00

Steps Forward: Integrative Mental Health is Gaining Ground "IndyWatch Feed Health"

The downside of over-relying on psychiatric meds for treatment is that people limited to just using them for treatment are not getting better  more of them are on disability for mental health reasons, and increasing numbers are disempowered by the long-term effects of psychiatric medications.

Now we know we need to rethink psychiatry and our responses to madness but what is the best name for the improved model of mental healthcare we are reaching for? We need both a model of care and a brand that empowers a change to optimal mental and physical health and uses the full spectrum of effective, evidence-based treatments.1

The term Integrative Medicine has been gaining ground in universities and healthcare centers which incorporate integrative therapies, e.g. Jefferson-Myrna Brind Center for Integrative Medicine is part of Thomas Jefferson University, and Duke Integrative Medicine is part of Duke University. New training is available, e.g. The Integrative Health and Healing specialty of the Doctor of Nursing Practice at the University of Minnesota prepares graduates to work with individuals, families, communities and health systems in developing integrative approaches to health promotion, disease prevention and chronic disease management.

The integrative model of care implies we assess and treat the whole body-mind-spirit as a unit within the social system, using an integrated systems response. The brand integrative also suggests we take the best of diagnostics and treatment protocols from all cultures and weave them together into an improved model of care. An example is Open Dialogue, a systems approach to psychotherapy developed in Finland. Practitioners from the USA have been trained and can now amplify the success of treatment for US families in which one person has symptoms of severe mental distress.

Gaining Traction

On September 18, 2017, a gift of 200 million US dollars was given to the University of California, Irvine, to create new buildings and new programs dedicated to forwarding the model of integrative healthcare. $55 million will go to create buildings, including one named the College of Health Sciences. The balance of $145 million will be dedicated to new educational programming, endowing 15 faculty chairs, subsidizing research in promising integrative modalities, and expanding the clinical facilities that offer integrative healthcare to patients.

...

12:00

Scientists Call for Increased Transparency in Research "IndyWatch Feed Health"

The Collaboration for Research Integrity and Transparency (CRIT) is an inter-disciplinary initiative launched in 2016 to enhance the quality and transparency of the research base for medical products.

07:00

Chuck Norris Sues for MRI Dye Injuring His Wife "IndyWatch Feed Health"

By Dr. Mercola

Magnetic resonance imaging (MRI) is an imaging study that allows your physician to see detailed pictures of your organs and tissues. Raymond Damadian invented the machine and performed the first total body image in 1977.1 This process has been called the one of the greatest medical breakthroughs of the 20th century.

The MRI machine uses a large magnet, radio waves and a computer to take detailed cross-sectional pictures of your internal organs and tissues.2 The scanner looks like a tube with a table that enables you to slide into the tunnel of the machine to gather data. Unlike CT scans or X-rays that use ionizing radiation known to damage DNA, the MRI uses magnetic fields.

Images from an MRI give physicians better information about abnormalities, tumors, cysts and specific organ problems with your heart, liver, uterus, kidneys and other organs. In some instances, your physician may want an enhanced MRI, one using contrast agents to improve the clarity of the images produced. In one of every three MRIs with contrast, the agent used is gadolinium.3

What Is Gadolinium?

This is a chemical contrast medium or dye that is injected to enhance the quality of the images. Gadolinium is bonded to a chelating agent that is intended to reduce the toxicity of the chemical to your body as gadolinium is a dangerous heavy metal known to cause neurological damage. There are several products that include gadolinium, called gadolinium-based contrast agents (GBCA).4

The U.S. Food and Drug Administration (FDA) released guidelines on the use of GBCAs5 as they began an investigation into the potential health effects from brain deposits of the heavy metal. The FDA acknowledged that repeated use of GBCAs may result in gadolinium deposits in your brain and other tissues but has not determined if there are any adverse health effects from these deposits.

To reduce accumulation, the FDA recommends health care professionals limit use to circumstances where additional information garnered by the use of gadolinium is absolutely necessary....

Are Stents a Scam? "IndyWatch Feed Health"

By Dr. Mercola

Angioplasty is a surgical procedure often recommended after an arterial blockage has been found in the heart muscle. Your heart requires a strong oxygen and nutrient supply, like other muscles in your body. There are two major coronary arteries that supply the left and right sides of your heart. By branching into smaller arteries they are able to supply the entire muscle with blood.

The goal of coronary artery angioplasty is to repair or unblock the blocked artery. During the procedure the surgeon inserts a thin expandable balloon that is inflated to flatten the blockage against the arterial wall.1 After the balloon is removed, the surgeon often places a stent with the intention of keeping the artery open and blood flowing freely.

There are currently five types of coronary artery stents available, each with different advantages and disadvantages to placement.2 However, while the different types of stents offer options for those for whom a stent is absolutely necessary, research shows those with stable coronary artery disease, stable angina, do not require stents.

Recent Study Finds Stent Placement May Not Be Better Than Placebo

In a recent study published in The Lancet, researchers from Imperial College London investigated the difference between patients who had received a stent for stable angina and those who underwent a placebo intervention.3 In the short video above, lead author and interventional cardiologist Dr. Rasha Al-Lamee, describes the study and its results.

The researchers recruited 200 participants with severe single vessel blockage from five sites across the U.K.4 During the initial six weeks, all patients underwent an exercise test followed by intensive medical treatment. At that point they were randomly assigned to two groups. The first underwent a percutaneous intervention (PCI) during which coronary angioplasty was performed and a stent was placed. The second group also underwent a PCI procedure with an angiogram but without a balloon angioplasty or stent placement.5

For the following six weeks, neither the patient nor the physician knew if the patient received the stent. At the conclusion of the six weeks, patient...

Meet the Sacklers: The Family That's Killing Millions (Maybe More Than Stalin) "IndyWatch Feed Health"

By Dr. Mercola

The U.S. has a massive opioid addiction problem. According to the U.S. surgeon general, more Americans now use prescription opioids than smoke cigarettes,1 and addiction to narcotic pain relievers now costs the U.S. more than $193 billion each year. The Manchester, New Hampshire, fire department recently said it now responds to more calls for drug overdoses than fires.2 That's not so surprising when you consider that opioids are now the leading cause of death among Americans under the age of 50.3

The following graph by the National Institute on Drug Abuse shows the progressive incline in overdose deaths related to opioid pain relievers between 2002 and 2015.4 This does not include deaths from heroin addiction, which we now know is a common side effect of getting hooked on these powerful prescription narcotics. In all, we're looking at just over 202,600 deaths in this 13-year time frame alone.5

National Overdose Deaths

Misleading Marketing Created the Opioid Epidemic

How did we get into this mess? Part of the problem, from the very beginning, has been false advertising. This past summer I wrote about how a single paragraph in a 1980 letter to the editor in the New England Journal of Medicine became the basis of a drug marketing campaign that has since led hundreds of millions of people straight into the arms of addiction and/or death.

03:19

FDA Lies About Kratom Again to Foster Opioid Epidemic "IndyWatch Feed Health"

It is no secret that Americans are losing trust in large institutions that were once believed to be beyond reproach. The media, once considered a paragon of integrity, is viewed with cynicism and suspicion. Our former faith in governmental programs and the 'best and brightest' has plummeted steadily from doubt into resentment. So it seems politically foolish for the U.S. Food and Drug Administration, in the midst of its own opioid crisis, which has wrought hundreds of thousands of deaths, laid waste to the life prospects of millions, and lined the pockets of its unscrupulous partner corporations, to issue a warning against the use of a natural herb that combats opioid dependence, eliminates drug withdrawal, and kills pain. Of course, being a naturally-growing plant does not automatically qualify something as safe. There are, after all, varieties of poisonous mushrooms and berries, but people intuitively know to place a greater trust into organic substances.

02:49

Founder of Autism Non-Profit Found Dead in Canal "IndyWatch Feed Health"

By Heather CallaghanEditor

We regret to report to you that a well-known advocate for autistic people  Jeana Beck died approximately November 17th near an Oregon hotel room where she had been staying.

Beck was the founder of Unlocking Autism and was traveling with her 23-year-old autistic son for a work trip and staying at Rodeway Inn.

She reportedly went outside for a smoke break and never returned. She was reported missing. Tragically, her body was found the next night in a canal behind the hotel.

Strangely, police almost immediately ruled out foul play, according to health writer Erin Elizabeth of Healthnut News who has delved deep into the strange string of deaths that has rocked the alternative health community in the last year or so.

We have touched on some of those stories on dead doctors but apparently the number has reached above 70 in less than a two-year period.

Elizabeth notes another strange twist Beck was a supporter of Age of Autism, whose editor Dan Olmstead also died in an alleged suicide early this year.

The family, of course, wants answers and apparently isnt accepting the police explanation for Becks death. They rightfully want to know what happened...

02:01

C. asiatica ethanolic leaf extract diminished the anti-oxidant gene expression and induced anti-proliferative/cytotoxic effects in A549 cells. "IndyWatch Feed Health"

PMID:  J Med Food. 2017 Oct ;20(10):959-968. PMID: 29040016 Abstract Title:  Centella asiatica Fraction-3 Suppresses the Nuclear Factor Erythroid 2-Related Factor 2 Anti-Oxidant Pathway and Enhances Reactive Oxygen Species-Mediated Cell Death in Cancerous Lung A549 Cells. Abstract:  Centella asiatica is a tropical medicinal plant that is commonly used in traditional medicine. Medicinal properties of C. asiatica include anti-oxidant, anti-inflammatory, and anti-cancer activity. We investigated the anti-oxidant and anti-proliferative/cytotoxic effects of a semi-purified fraction of C. asiatica ethanolic leaf extract (C3) in cancerous lung A549 cells. C3 was obtained by silica column fractionation and identified by using thin-layer chromatography and gas chromatography mass spectrometry. Cytotoxicity of C3 in A549 cells was evaluated (cell viability assay-WST-1; 24h; [0.2-3mg/mL]) to determine an inhibitory concentration (IC50). Intracellular reactive oxygen species (IROS), mitochondrial membrane potential (flow cytometry), malondialdehyde (MDA), lactate dehydrogenase (LDH) (spectrophotometry), glutathione (GSH), oxidised glutathione (GSSG), adenosine triphosphate levels, caspase activity (luminometry), and DNA damage (comet assay) were evaluated. Protein expression (Nrf-2, p53, Bax, Bcl-2, and HSP-70) and gene expression (Nrf-2, GPx, SOD, CAT, c-myc, and OGG-1) were quantified by western blotting and quantitative polymerase chain reaction (qPCR),respectively. C3 dose dependently decreased A549 cell viability. The IC50 of C3 increased MDA, IROS, mitochondrial depolarization, LDH, caspase (-8, -9, -3/7) activity, DNA damage, GSH levels, Nrf-2 protein expression, HSP-70 protein expression, and OGG-1 gene expression (P

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01:54

Asiatic acid nullified aluminium toxicity in in vitro model of Alzheimer's disease. "IndyWatch Feed Health"

PMID:  Front Biosci (Elite Ed). 2018 Jan 1 ;10:287-299. Epub 2018 Jan 1. PMID: 28930619 Abstract Title:  Asiatic acid nullified aluminium toxicity in in vitro model of Alzheimer's disease. Abstract:  Aluminium (Al) is a ubiquitously distributed environmental toxicant that lacks biological functions; however, its accumulation in the brain has been demonstrated to be linked to several neuropathological conditions particularly Alzheimer's disease (AD). Asiatic acid (AA), a triterpene extracted from Centella asiatica, has been reported to cross the blood brain barrier and also displayed antioxidant and neuroprotective activities. The present study was aimed to explore the neuroprotective effect of AA against aluminium maltolate (Al(mal)3) induced neurotoxicity by assessing cell viability, mitochondrial membrane potential, levels of reactive oxygen species (ROS), DNA damage and apoptosis (Hoechst and dual staining, comet assay; expressions of pro-apoptotic, anti-apoptotic and signaling indices) via AKT/GSK-3 signaling pathway in SH-SY 5Y  neuroblastoma cells. Pre-treatment with AA significantly enhanced cell viability, attenuated rotenone-induced ROS, mitochondrial membrane dysfunction and apoptosis regulating AKT/GSK-3 signaling pathway. Downregulation of Al induced neurodegeneration may be one of the approaches to control the impairment of metal ion homeostasis leading to neuronal injury in  early development of AD. However, more extensive work in animal model is desirable to confirm its neuroprotective action.

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01:10

Excessive sugar-sweetened beverage consumption impacts early childhood immune system health adversely, possibly before the development of obesity. "IndyWatch Feed Health"

PMID:  Child Obes. 2017 Nov 17. Epub 2017 Nov 17. PMID: 29148828 Abstract Title:  Increased Cellular Aging by 3 Years of Age in Latino, Preschool Children Who Consume More Sugar-Sweetened Beverages: A Pilot Study. Abstract:  BACKGROUND: Previous studies in adults and older children find that sugar-sweetened beverage (SSB) consumption increases risk for obesity and cellular aging, as measured by leukocyte telomere length (LTL).METHODS: In a previously described, San Francisco-based Latino birth cohort, where telomere length was measured at birth, we evaluate the relationship between beverage consumption (including SSB and 100% fruit juice), obesity, and LTL at 2-3 years old, as well as change in LTL from birth. LTL (T/S Ratio) was measured in 61 children (mean 2.4 years0.6 standard deviation). Multivariable linear regression models are used to ascertain beverage type and obesity as independent predictors of LTL and change in LTL.RESULTS: Mean telomere length was 1.580.20 (T/S Ratio) and mean yearly change was -0.08-0.09 (T/S Ratio). Predictors of shorter telomere length at age 2-3 included increased consumption of SSB (Beta Coeff=-0.009 95% CI [-0.02 to -0.0008]; p=0.03). Telomere length at birth was the strongest predictor of rate of attrition from birth to 2-3 years of age and males tended to have more rapid attrition.CONCLUSION: Excessive SSB consumption impacts early childhood immune system health adversely, possibly before the development of obesity.

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01:05

10 Things for Which Im THANKFUL: How Bout YOU? "IndyWatch Feed Health"

Thanksgiving is upon us here in the USA. But truth is, amidst the assorted social gatherings, feasting, travel, etc., the "thanks" of it all is often forgotten. Don't know about you, but in my mind that's a missed opportunity. Tap-in, okay?

00:23

This study found increased odds of Toxoplasma exposure in individuals with a recent onset of psychosis. "IndyWatch Feed Health"

n/a PMID:  PLoS Negl Trop Dis. 2017 Nov ;11(11):e0006040. Epub 2017 Nov 6. PMID: 29108011 Abstract Title:  Evidence of increased exposure to Toxoplasma gondii in individuals with recent onset psychosis but not with established schizophrenia. Abstract:  A possible role for Toxoplasma gondii in the etiopathogenesis of schizophrenia is supported by epidemiological studies and animal models of infection. However, recent studies attempting to link Toxoplasma to schizophrenia have yielded mixed results. We performed a nested case-control study measured serological evidence of exposure to Toxoplasma gondii in a cohort of 2052 individuals. Within this cohort, a total of 1481 individuals had a psychiatric disorder and 571 of were controls without a psychiatric disorder. We found an increased odds of Toxoplasma exposure in individuals with a recent onset of psychosis (OR 2.44, 95% Confidence Interval 1.4-4.4, p<.003). On the other hand, an increased odds of Toxoplasma exposure was not found in individuals with schizophrenia or other psychiatric disorder who did not have a recent onset of psychosis. By identifying the timing of evaluation as a variable, these findings resolve discrepancies in previous studies and suggest a temporal relationship between Toxoplasma exposure and disease onset.

00:05

Bumps on Elbows: Causes, Effective Treatments and When to See a Doctor "IndyWatch Feed Health"

Bumps on elbows can appear due to a number of different causes ranging from an eczema rash to a large painful cyst. Depending on the reason for elbow bumps, you can also have a variety of other symptoms. Sometimes, the bumps on your elbow look like red spots, tiny white pimple-like spots or skin colored bumps. Or, the bumps can appear as a rash with itchy red patches of raised skin.

Getting rid of bumps from your elbow depends on what is causing the skin lesions. Some dermatological conditions like dermatitis herpetiformis or a ganglion cyst need professional medical care. However, there are many natural home remedies that can help to soothe pain and irritation in your elbows that psoriasis, eczema, or heat rashes cause.

In this article, you will find out what could be causing bumps on your elbows. In many cases, you can treat these elbow bumps at home with effective remedies using natural ingredients. You will also learn when you should see a doctor for lumps on your elbow.

Symptoms of Bumps on Elbows

Your elbows have to endure a lot of daily wear and tear. The constant use of your elbows can cause inflammation and swelling in the joints. Constant elbow movement can also make the skin on your elbow rough and scaly and this can lead to some dermatological issues.

For example, dry skin on your elbows can cause symptoms like extreme itchiness, scaling over the red patch of skin, and sometimes oozing fluid. It is very common for eczema and psoriasis to affect the elbows and knees. In some cases, the raised red bumpy skin can appear as a rash that has been caused by scabies mites or Lymes disease from a tick bite.

Other times, inflammation of the elbow joint can cause a protruding lump on your elbow that may or may not be painful.

Causes of Bumps on Elbows

Lets look in more detail at the causes of bumps and red rashes on your elbow and what you can do about it.

 

Red rash on elbows caused by eczema

Eczema is a common reason for an itchy red rash on your elbows that makes your skin itchy and bumpy.

Eczema can affect people of all ages and is common if you suffer from allergies or asthma. According to the American Academy of Dermatology, eczema often starts as a rash in the creases of the elbow skin. This can develop into an itchy, scaly rash that looks bumpy. Over time, permanent bumps on your elbow can appear. Although eczema often affects the elbows, patches of itchy rashes can appear anywhere on your body.3

Dr. William Blahd on WebMD reports that scratching the eczema rash on your elbow can cause the skin to turn leathery. You may also notice fluid-filled blisters that weep fluid when scratched. In...

00:05

Treatment of fever of unknown origin by homeopathy "IndyWatch Feed Health"

PMID:  Harefuah. 1994 Mar 15 ;126(6):317-20, 368, 367. PMID: 8194786 Abstract Title:  [Treatment of fever of unknown origin by homeopathy]. Abstract:  2 cases of fever of unknown origin (FUO) treated successfully by homeopathy are presented. The purpose is to show the effectiveness of homeopathy as adjuvant therapy for those in whom the full medical diagnostic process, assessment, and treatment are not effective. In a 12-year-old boy fever and abdominal pain persisted for several months despite various medical treatments. All symptoms disappeared following homeopathic treatment. In a 66-year-old man fever and other symptoms also disappeared after such treatment. We emphasize that homeopathy is not a substitute for the full conventional medical diagnostic investigation and treatment of FUO. Homeopathy should only be practiced by medical doctors to avoid, to the greatest extent, diagnostic and therapeutic errors.

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Tuesday, 21 November

23:21

Chlorella: Super Food for Healing and Detox "IndyWatch Feed Health"

Green chlorella. detox superfood. close - up

by Paul Fassa
Health Impact News

Chlorella is a super-food that offers many detoxification and health boosting qualities. It is single cell algae that can be produced in open pools of fresh water with lots of exposure to sunlight. Since each cell can only be seen through a microscope, it is categorized as a microalgae.

Researchers in the West have become increasingly aware of its extremely high nutrient density over the past 100 plus years.

A Summary from a Recent Review of Many Chlorella Studies

In 2016, the journal Current Pharmaceutical Design published a review, Chlorella vulgaris: A Multifunctional Dietary Supplement with Diverse Medicinal Properties. Here are some excerpts from the abstract of that meta-study review:

Chlorella vulgaris [vulgaris means common] is a green unicellular microalgae with biological and pharmacological properties important for human health.

C. vulgaris contains a unique and diverse composition of functional macro- and micro-nutrients including proteins, omega-3 polyunsaturated fatty acids, polysaccharides, vitamins and minerals. Clinical trials have suggested that supplementation with C. vulgaris can ameliorate hyperglycemia, and protect against oxidative stress, cancer and chronic obstructive pulmonary disease.

In this review, we summarize the findings on the health benefits of Chlorella supplementation and the molecular mechanisms underlying these effects. (Abstract source)

Chlorella is not some sort of exaggerated super-food fad; chlorella could replace a lot of supplements that are not as natural.

What Chlorella Can Do for You

Chlorella single celled algae are harvested from open pools or pools within large greenhouses that allow plenty of sunlight to create the photosynthesis that is essential to this algaes extremely high chlorophyll content.

Chlorophylls composition is similar to human blood, except the central atom in chlorophyll is magnesium. Human blood cells have iron as its central atom. This is...

23:20

Arizona Judge: Child Removed from Home Illegally Only Reason Was Child Was Adoptable "IndyWatch Feed Health"

adoptuskids.org

Adopting children is big business. Websites like adoptuskids.org advertise available children, and give advice on how to adopt. With a huge need to find foster parents so states can collect federal funds for foster children, this website states You dont have to be a perfect parent to try and entice people to become foster parents. Ironically, many children are taken out of their loving homes simply because their biological parents are not perfect.

Commentary by:
Terri LaPoint, Assistant Editor MedicalKidnap.com
Brian Shilhavy, Editor
Health Impact News

One of the dirty little secrets of Child Protective Services is that children are sometimes taken from their homes, and their parents rights ended, simply because the children are adoptable.

Now, in a stunning reversal of a termination of parental rights decision, a Court of Appeals has concluded that the Arizona Department of Child Safety (DCS) took children from their mother primarily because her children were considered adoptable.

This admission is now part of the court record.

This confirms what many parents and social worker insiders have told Health Impact News that one of the reasons that children are taken even from good, loving homes is because of their adoptability, not just in Arizona, but in every state.

There is a great deal of federal funding in adopting out children to strangers; thus, children have literally become a commodity to be seized and sold.

Devani photo from AZ Childrens Lives Matter FB page

Devani was taken from her mother by Arizona DCS for false allegations, then placed into a foster home that was a pornographic pedophile ring. With her blond hair and blue eyes, she was very adoptable....

23:12

Russia Confirms Presence of Mysterious Cloud of Extremely High Radiation "IndyWatch Feed Health"

radiation cloud

By Heather CallaghanEditor

A Russian region is literally experiencing radiation nearly 1,000x the norm but from where? What about the cloud over Europe in October?

About a month ago, a mysterious radiation cloud was witnessed over Europe, but the source remains unknown, despite speculation that there could have been a nuclear accident in Russia or Kazakhstan, Zero Hedge reports.

Today, Russian officials confirmed the previous reports of radiation spikes over the Ural mountains. Additionally, the Russian Meteorological Service said noted a release of Ruthenium-106 in the southern Urals before October and it was classified as extremely high contamination.

SEE: NASA Releasing Artificial Clouds Over Maryland Coast

...

23:07

Aconit proved to be effective for children's postoperative agitation with 95% good results. "IndyWatch Feed Health"

PMID:  Pediatrie. 1990 ;45(7-8):465-6. PMID: 2170921 Abstract Title:  [Aconite in homeopathic relief of post-operative pain and agitation in children]. Abstract:  Despite the use of modern analgesic methods and an improved use of narcotics, the combination pain-agitation sometimes persists in the recovery-room. Aconit seems to be an appropriate homeopathic treatment in this case. To prescribe it, the following conditions must be combined: violence and suddeness of the stress bringing about intense and anguish. The study included 50 children with such symptoms; it was carried out double-blind, the children being given either placebo or Aconit. Aconit proved to be effective for children's postoperative agitation with 95% good results. It is usually stated in such studies that the placebo effect is high and may reach rates higher than 30%. Aconit is an amazing cure when well prescribed, as much for the speediness of its action as for its efficiency. This remedy has a place in the recovery-room and should be in every physician's emergency case. The fundamental research could specify how the remedy works and may be discover other molecules effective for stress.

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22:43

Homeopathic metaphylaxis is significantly effective compared with placebo and routine low-dose antibiotic metaphylaxis. "IndyWatch Feed Health"

PMID:  Altern Ther Health Med. 1999 Sep ;5(5):64-8. PMID: 10484832 Abstract Title:  Homeopathy versus antibiotics in metaphylaxis of infectious diseases: a clinical study in pig fattening and its significance to consumers. Abstract:  CONTEXT: Due to the conditions of modern industrial pig fattening in intensive livestock farms, 24% to 69% of the animals become ill. The antibiotic metaphylaxis that is routinely administered leads to several problems in animals, human health, and the environment.OBJECTIVE: To investigate whether a homeopathic metaphylaxis is effective and potentially useful for replacing antibiotic metaphylaxis.DESIGN: Animal subjects were divided into groups of 10 per pen, 2 pens sharing 1 trough. Twenty pigs were randomly assigned within a stall and were administered either antibiotics, homeopathy, or placebo.SETTING: A typical intensive livestock farm in Northern Germany.PARTICIPANTS: 1440 piglets.INTERVENTION: Homeopathic metaphylaxis is compared with placebo, the routine low-dose antibiotic metaphylaxis, and an antibiotic metaphylaxis in therapeutic dosage.MAIN OUTCOME MEASURES: Incidence of diseases in general and of diseases of the respiratory tract.RESULTS: Homeopathic metaphylaxis is significantly effective compared with placebo and routine low-dose antibiotic metaphylaxis for incidence of disease and rate of disease of the respiratory tract among the animals studied. Only by increasing the dosage of antibiotics to a therapeutic level does antibiotic metaphylaxis surpass homeopathic metaphylaxis.CONCLUSIONS: An unacceptably high percentage of pigs in modern livestock management become ill, suffering mainly from diseases of the respiratory tract. The routine antibiotic dosage of metaphylaxis is too low to be effective. As a result, the problems of resistance and danger to human health and the environment are increasing. To confirm whether antibiotic metaphylaxis may be replaced by homeopathic metaphylaxis, this study should be repeated independently.

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22:37

Arizona Judge: Child Removed from Home Illegally Only Reason Was Child Was Adoptable "IndyWatch Feed Health"

adoptuskids.org

Adopting children is big business. Websites like adoptuskids.org advertise available children, and give advice on how to adopt. With a huge need to find foster parents so states can collect federal funds for foster children, this website states You dont have to be a perfect parent to try and entice people to become foster parents. Ironically, many children are taken out of their loving homes simply because their biological parents are not perfect.

Commentary by:
Terri LaPoint, Assistant Editor MedicalKidnap.com
Brian Shilhavy, Editor
Health Impact News

One of the dirty little secrets of Child Protective Services is that children are sometimes taken from their homes, and their parents rights ended, simply because the children are adoptable.

Now, in a stunning reversal of a termination of parental rights decision, a Court of Appeals has concluded that the Arizona Department of Child Safety (DCS) took children from their mother primarily because her children were considered adoptable.

This admission is now part of the court record.

This confirms what many parents and social worker insiders have told Health Impact News that one of the reasons that children are taken even from good, loving homes is because of their adoptability, not just in Arizona, but in every state.

There is a great deal of federal funding in adopting out children to strangers; thus, children have literally become a commodity to be seized and sold.

Devani photo from AZ Childrens Lives Matter FB page

Devani was taken from her mother by Arizona DCS for false allegations, then placed into a foster home that was a pornographic pedophile ring. With her blond hair and blue eyes, she was very adoptable....

22:33

Klimaktoplan has an anti-proliferative effect on breast cancer cells. "IndyWatch Feed Health"

PMID:  Arch Gynecol Obstet. 2013 Oct ;288(4):833-8. Epub 2013 Apr 18. PMID: 23595584 Abstract Title:  Anti-proliferative effect of Klimaktoplan on human breast cancer cells. Abstract:  OBJECTIVE: With the health concerns of menopausal hormone replacement therapy, alternatives have been sought. Klimaktoplan is a homeopathic formulation consisting of four main components and has been used for relief of menopausal symptoms for a long time. The study investigated the safety of Klimaktoplan through its effect on the proliferation of breast cancer (MCF-7) and non-malignant mammary epithelial cells (MCF-10A).METHODS: MCF-7 and MCF-10A cells were cultured in 312.5, 625, and 1,250g/ml Klimaktoplan. 17-Beta estradiol (E2) and medroxyprogesterone 17-acetate (MPA) were used for comparison with Klimaktoplan. E2 only (0.001, 0.01, and 0.1 M), and the combination of E2 (0.001, 0.01, and 0.1 M) and MPA (0.01, 0.1, and 1 M) were tested. Control cells for Klimaktoplan and E2 groups were treated with dimethylsulfoxide (DMSO), and DMSO + ethanol was used for the combination group. Cellular proliferation was evaluated by the formation of insoluble formazan after incubation of 4 days.RESULTS: Klimaktoplan had a concentration-dependent anti-proliferative effect on breast cancer cells at 625 and 1,250 g/ml, while not affecting proliferation of non-malignant mammary cells at any tested concentration. The effect of lactose was evaluated as lactose (the adjuvant of Klimaktoplan) affect cell growth.E2 and lactose increased the proliferation of both malignant and non-malignant cells. The effect of E2 + MPA on the proliferation of malignant and non-malignant mammary cells was lower than estradiol only, but was higher than control.CONCLUSIONS: Klimaktoplan has an anti-proliferative effect on breast cancer cells, but not for non-malignant mammary epithelial cells, unlike E2 and E2 + P. With further research, KP would be a good alternative or additive in women with menopausal symptoms who wish to avoid conventional E or E + P hormone therapy.

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22:25

Traumel S may be recommended to be used in combined therapy for salivary glands inflammatory and dystrophic disorders treatment. "IndyWatch Feed Health"

PMID:  Stomatologiia (Mosk). 2012 ;91(4):38-40. PMID: 23011333 Abstract Title:  [Antihomotoxic therapy in patients with inflammatory and dystrophic salivary gland diseases]. Abstract:  Traumeel S was used as monotherapy for salivary glands inflammatory and dystrophic disorders. The study showed the drug to be especially efficient by exacerbation of the recurrent disease but the results were poor by indolent disease and on the latter stages of dystrophic disorder. Traumel S may be recommended to be used in combined therapy for salivary glands inflammatory and dystrophic disorders treatment.

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22:19

3-Ingredient Mixture Improves Vision and Liver Detoxification "IndyWatch Feed Health"

Few things are better for your health and your wallet than homemade vegetable juice. After all, juicing is an easy, time-saving way to get more fruits and vegetables in your diet and use up leftover produce before they go bad (3). As long as you moderate your intake to account for the natural sugars and... View Article

The post 3-Ingredient Mixture Improves Vision and Liver Detoxification appeared first on Healthy Holistic Living.

22:00

Dr Ron Unfiltered Uncensored Medical Mistakes and Hospitals "IndyWatch Feed Health"

Drs Ron Gerry and Dan with over 150 years of medical experience discuss issues in medicine that you don't hear on the main stream outlets for news. Archived episodes are on itunes, google play, blubrry, stitcher, itune radio and others.

21:41

Brain Regeneration: Can Infrared Light Reverse Parkinsons and Alzheimers? "IndyWatch Feed Health"

Contrary to conventional wisdom, brain regeneration is possible. One promising therapy that promotes neurogenesis and is effective in pre-clinical studies of Alzheimers and Parkinsons is near infrared light therapy, and it may improve other mental illnesses and neurodegenerative disorders including dementia, stroke, ALS, and traumatic brain injury as well.

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21:27

LED is a useful light source for deactivating the cancer cells because it can excite the sensitizers. "IndyWatch Feed Health"

PMID:  Bioorg Med Chem. 2017 Oct 21. Epub 2017 Oct 21. PMID: 29108834 Abstract Title:  Photodynamic therapy of human biliary cancer cell line using combination of phosphorus porphyrins and light emitting diode. Abstract:  A series of phosphorus porphyrin complexes ([(RO)2P(tpp)]Cl, tpp=tetraphenylporphyrinato group, R=-(CH2CH2O)m(CH2)nH; 1a: m=2, n=2; 1b: m=2, n=4; 1c: m=2, n=6; 1d: m=3, n=6) were used for the photodynamic therapy (PDT) of human biliary cancer cell line (NOZ) when exposed to the irradiation of light emitting diodes (LEDs). A Dulbecco's modified Eagle's medium (DMEM) containing NOZ cells (2000cellwell(-1)) and 1 (0-100nM) was introduced into a 96-well microplate and incubated for 24h to accumulate 1 into the NOZ cells and to multiply the NOZ cells until the cell number reached 10(4)cellswell(-1). After replacing the DMEM medium containing 1 with a fresh DMEM medium without 1, the plates were irradiated for 30min at 610nm. After incubation was performed for 24h in dark conditions, the cell viability of the NOZ cells was determined using the MTT assay. The half maximuminhibitory concentrations 50 (IC50) of 1a-1d were found to be in the range of 33.7-58.7nM for NOZ. These IC50 values for the NOZ were one hundredth the IC50 value (7.57M) for mono-l-aspartyl chlorin e6 (laserphyrin). Thus, it was found that the PDT activity of 1a-1d was much higher than the mono-l-aspartyl chlorin e6. Similarly, IC50 vales of 1a-1d for HeLa cells were found to be 27.8-52.5nM. This showed that 1a-1d had high photodynamic activity in cancer cells. At the same time, it was speculated that an LED is a useful light source for deactivating the cancer cells because it can excite the sensitizers with peak width in their absorption spectra using the light of the specified wave length with band width of 10-20nm; LEDs provide a homogeneous light distribution for the target cells.

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21:09

new research findings two "IndyWatch Feed Health"

Sunspots and Cell Towers Fueled the Northern California Firestorm



Forest fire scarred mountain slopes in the Colorado Rockies, where pine trees were stripped bare by the fire. [Credit: James Grundvig, August 11, 2017.]
Two seismic, overlapping eventsone celestial, the other manmadecreated the unique condition igniting the Northern California fires that swept through wine country on October 8 and 9. The chain reaction setoff more than a dozen clusters at the same time scattered across multiple counties on one hellish night.
At first, authorities suspected arson. Journalists absurdly blamed ISIS, then Mexican drug cartels for coordinating attacks. Napa and Sonoma Counties are not the regions to grow cannabis; pot farms are located far north along the coast.
The wildfires werent wild at all. The houses cooked from the inside out. They often burned from the top of the roofs, incinerating the walls, floors, appliances, and cladding down to the foundation. Yet, 90 percent of the trees on the properties remained standing with leaves on the branchesnot burnt, merely dried out. It was as if a neutron bomb had detonated burning everything manmade, but leaving the greenery alone.



Drone footage, photos, and eyewitness accounts confirmed that was the case. Pine trees trapped by the fires stood unscathed, while the houses burned. Scarred shells of cars seen in photo after photos had their tires vaporized to the rims, the windshields melted away, and the metal bodies warped by the intense heat. None of it was normal or...

20:54

The European Health Parliament: Bogus Institution Is Industry Front "IndyWatch Feed Health"

By John Stone Our elected politicians may not be class I collectively respect, but at least they bother to get themselves elected. Recently our friends at the British based journal and group The Informed Parent received a letter announcing: My...

20:00

Holiday Reading List from Skyhorse Publishing "IndyWatch Feed Health"

This holiday season, we're thankful for Skyhorse Publishing in New York. Publisher Tony Lyons is not only an autism Dad himself, but he's a brave, sometimes lone voice in the publishing world for every topic within the spectrum that is...

19:41

Tyson Foods Responsible for Chemical Release That Led to Mass Fish Death "IndyWatch Feed Health"

By Heather CallaghanEditor

Tyson Foods the largest U.S. chicken producer has pleaded guilty in a chemical incident that led to the deaths of over 100,000 fish.

The Arkansas-based poultry giant has claimed full responsibility for accidentally releasing an acidic chemical used in chicken feed that wound up in Monett, Missouris wastewater treatment system.

In late September, the company landed in federal court in Springfield, Missouri, and pleaded guilty for two criminal charges of violating the Clean Water Act. The charges are from the 2014 incident at its slaughter and processing facility in Monett, Missouri, the DOJ stated.

EcoWatch reports [emphasis added N.B.]:

According to DOJ, one of the ingredients Tyson used in its chicken feed is a liquid food...

18:57

Neonicotinoids are Officially Toxic to Songbirds "IndyWatch Feed Health"

neonicotinoids songbirds neonics birds

By Heather CallaghanEditor

A groundbreaking study is showing once and for all that despite safety claims, insecticides called neonicotinoids have a direct effect on the health and travels of songbirds.

Inhabitat reports:

Reportedly, this is the first study to show that imidacloprid (neonicotinoid) and chlorpyrifos (organophosphate) which are two of the most widely-used insecticides are toxic to seed-eating songbirds.

Said [Christy Morrissey, a professor at the University of Saskatchewan], Studies on the risks of neonicotinoids have often focused on bees that have been experiencing population declines. However, it is not just bees that are being affected by these insecticides.

18:48

Individual Mandate Eliminated? "IndyWatch Feed Health"

Lawmakers may still have a go at changing healthcarethrough their tax plan.

From The New York Times:

Senate Republicans have decided to include the repeal of the Affordable Care Acts requirement that most people have health insurance into the sprawling tax rewrite.

They also revealed late Tuesday they would set all of their tax cuts for individuals to expire at the end of 2025, to comply with a procedural requirement. Their deep cut in the corporate tax rate would remain permanent.

Repealing the mandate, a longstanding Republican goal, would save hundreds of billions of dollars over the next decade.

Comment: The change would save money because although there would be less tax revenue there would also be less subsidy paid.  From the beginning, ANH-USA has criticized the Obamacare mandate, since it essentially forces patients interested in natural health to pay twice: once for government insurance that covers a wide array of services they will likely never use, and once out-of-pocket for the integrative health services they desire.

 

 

18:32

I Saw Death in Her Eyes. Chuck Norris Warns About a Common Medical Procedure That Almost Killed His Wife, yet Millions of Americans Undergo It Every Year "IndyWatch Feed Health"

Source: I Saw Death in Her Eyes. Chuck Norris Warns About a Common Medical Procedure That Almost Killed His Wife, yet Millions of Americans Undergo It Every Year For more content like this visit REALfarmacy.com.

by Yelena Sukhoterina Some medical procedures are so common that few ever question their safety until it is too late. Chuck Norris, a famous American actor and martial artist, recently had to witness his wife go through agony feeling helpless as the doctors rushed to find an answer to why Gena Norris was dying []

Source: I Saw Death in Her Eyes. Chuck Norris Warns About a Common Medical Procedure That Almost Killed His Wife, yet Millions of Americans Undergo It Every Year Learn more at REALfarmacy.com - Healthy News and Information.

18:25

Enormous economic value of vaccination the case is clear "IndyWatch Feed Health"

The Skeptical Raptor, stalking pseudoscience in the internet jungle.

The enormous economic value of vaccination that is, the economic benefits of a vaccine far outweighs the costs is often overlooked, especially by those who invent some massive conspiracy by Big Pharma to push vaccines. The standard anti-vaccine trope is that vaccines are a gargantuan profit center for pharmaceutical companies. That would be false.

Skeptical Raptor

17:47

Campaign to Restore Child Health: PANDAS, Autism and Vaccine Injury "IndyWatch Feed Health"

PANDAS and PANS (Pediatric Autoimmune Neurodegenerative Disease Associated with Strep and/or other pathogens) are autoimmune conditions caused by bacteria or viruses and result in symptoms that are mainly behavioral in nature. Parents report overnight changes in their childrens aggression, tic patterns and skill levels. Many doctors do not recognize these conditions and often their children are left struggling in medical crisis.  Left untreated, the disease can become very difficult to treat and may result in permanent injury. This is Tiffany and Joshs story.

As these issues become more common, it is imperative that we bring awareness to the plight of our families and advocate for appropriate medical care for our children. Do you have a story similar to Tiffany and Josh. Make your own video and use #restorechildhealth and #worldmercuryproject.

 

Also watch Robert F. Kennedy, Jr. launch the Campaign to Restore Child Health

The post Campaign to Restore Child Health: PANDAS, Autism and Vaccine Injury appeared first on World Mercury Project.

17:30

Lancet retracts and replaces news story about controversial abortion drug "IndyWatch Feed Health"

The Lancet has retracted a journalist-written piece about a controversial drug used off-label to induce abortions, and replaced it with a corrected version. In the retraction notice, the journal said it removed the information that we believe to be inaccurate. The article, first published Oct. 28, 2017, highlights Pfizers decision to withdraw the drug, misoprostol, []

The post Lancet retracts and replaces news story about controversial abortion drug appeared first on Retraction Watch.

17:15

Researchers Discover Effective Natural Anti-cavity Herb "IndyWatch Feed Health"

By Mae Chan

As a natural traditional Chinese medicine, Galla Chinensis has been widely used since ancient times for its astringency, stypticity, detoxification, and antibacterial activity. In a new finding, researchers in China report that active ingredients in the herb could one day lead to natural anti-cavity products.

Childrens cavities are on the rise, and children today who have cavities are requiring more expensive and extensive dental surgery to hide the problems of dental decay.

The U.S. Centers for Disease Control and Prevention reported there was an increase in the number of preschool children with cavities, for the first time in 40 years.

The scientists from West China School of Stomatology and Academic Centre for Dentistry Amsterdam have figured out the main active ingredient of Galla Chinensis, a natural herb, and further improved its anti-caries efficacy. Their findings are published in The Open Dentistry Journal.

To maintain a healthy mouth, the oral environment must be relatively neutral. When the environment in the mouth becomes more acidic, dental cavities or other disorders may develop. Galla Chinensis was revealed to inhibit the acid production of caries-associated bacteria as well as make teeth more resistant to acidic attack.

Galla Chinensis originates from the abnormal growth of the Rhus leaf tissue in response to secretion of parasitic aphids (family Pemphigidae). It has been used for thousands of years due to its antibacterial, antiviral, anticaries, antioxidative, anticancer, live-protective, antidiabetic, antidiarrheal, anti-inflammatory and antithrombin activity.

...

17:00

The Angry Congressman: Tim Murphys Lack of Insight "IndyWatch Feed Health"

In chalking up a mass shooting to mental illness, Trump is ripping pages from another Republicans playbook. For years, before Trump was ever elected, no one wanted to draw a link between mental illness and capacity for violence in black Sharpie more than Pennsylvania congressman Tim Murphy did.

Thought leaders lambasted Murphy last month for his anti-choice voting record after it was revealed that he urged his mistress to consider abortion during a pregnancy scare. He voted for the Pain-Capable Unborn Child Protection Act, which bans abortions after 20 weeks of pregnancy, the same week the country learned he would have preferred to eliminate his own unborn child.

But these pundits missed the most spectacular part of Rep. Murphys hypocrisy and it has nothing to do with abortion or reproductive rights.

Along with the fact that Murphy is not pro-life, more news spilled about the man who represents Pennsylvanias 18th congressional district and revealed that hes unmoored. Murphys not unstable; hes way more than that. His chief of staff, Susan Mosychuk, in a memo about her boss, wrote that he was hostile, erratic . . . angry, aggressive and abusive as well.

The same memo describes the congressman driving in a downpour while texting and watching Youtube videos on his ipad. And, in petulance that seems excessive even for a politician, he pushed papers to the floor and then ragingly required his staff to pick them up. All these antics emanated from the expert author of the book The Angry Child.

Those allegations of dangerous behavior and the licensed psychologists lack of insight into his own actions are enough to commit him, involuntarily, to psychiatric treatment under the Helping Families in Mental Health Crisis Act. The bill was passed by the House last summer after being championed by Rep. Murphy for years as his signature legislation after the Sandy Hook Elementary school shooting in December 2012.

The Helping Families billwhich effectively eliminated the old standard of being a danger to others or self in order to be involuntarily committedwas Murphys promise to the country that his profession could eliminate unfathomable massacres, despite scientific evidence that people diagnosed as mentally ill are more likely to be...

15:30

Bengaluru lads initiative provides ray of hope for remote Hussainpura "IndyWatch Feed Health"

Bengaluru: Natives of Hussainpura village of Pavagada taluk in Tumakuru district no longer need to cross the Andhra Pradesh border daily to fetch drinking water. They also need not travel 38 kilometres through forest areas to the nearest hospital for any medical emergency, after a Primary Health Centre was set up within the remote village itself.

All this happened thanks to Operation Blue Water, a social initiative led by Rahul Prasad, a city youngster and social activist who converged passion and practical knowledge he attained at college to better hundreds of lives at the village. He is now training villagers to be self-sustainable and self-helping.

In a chat with Deccan Chronicle Rahul said, The geometric placement of the village at the remote Karnataka-Andhra border had been the major hindrance towards any welfare activity in the village for the past ten to fifteen years. Taking people into confidence and making them aware of the fact that they need to change towards better was a major challenge we faced during the intervention.

The youngster and his team had planned to ensure availability of drinking water, but they soon realised that many in the village were suffering from dengue or chikungunya. Dental and skeletal fluorosis was also rampant among them.

According to the activist, as many as 800 people in the village had little access to medical facilities to get treated for the diseases. WhatsApp and social media groups came handy as I could get proper prescriptions from doctors (especially Dr Soumya Prasad from Delhi) and get them transported in bulk towards the village with the help of my friends and like-minded activists as soon as possible, he explained.

Team Operation Blue Water initially set up reverse osmosis pumps at the school and at the centre of the village. They then trained two ASHA workers on how to administer first aid, distribute medicines and provide guidelines on running a primary health centre.

The intervention also helped us forward information to respective tahsildars and government officials from the village to facilitate pensions for widows, older citizens and the specially-abled. Sustaining and following up the social initiative on a monthly basis and inspiring more social workers to help people lead better lives is what we are working at the moment, concluded Rahul, a social work student from St Josephs College, Bengaluru.

*Original article online at http://www.deccanchronicle.com/nation/current-affairs/211117/bengaluru-lads-initiative-provides-ray-of-hope-for-remote-hussainpura.html...

15:00

Ebensburg Municipal Authority votes to keep fluoride in water "IndyWatch Feed Health"

EBENSBURG Water from Ebensburg will continue to include fluoride for now.

After hearing pleas from three area dentists, a state oral health advocate and a concerned resident, Ebensburg Municipal Authority Members voted unanimously Monday to rescind last months action to remove the fluoride.

The fluoride was never removed, authority Chairman Gerald McMullen said, explaining the action required state notification and other tasks that were not complete.

We formally approved it, but we were still in the process, McMullen said.

Ebensburg dentist Philip Woo, Lilly dentist Nicole Falchini Oravec and Westmont dentist Robert Callahan urged authority members to continue adding fluoride, citing oral health benefits.

I feel this is going to be a major detriment for this area, Oravec said of the authoritys previous action removing fluoride.

We are going to see it 10 or 15 years from now. Those are the teeth that will develop problems. We need to do what we can to supplement that.

The issue could come up again as early as next month.

McMullen first suggested the authority should delay implementation until a fifth board member joins the authority next month. But authority member Doug Tusing said the proper action would be to rescind the previous action. Solicitor Theresa Homady agreed.

Board member Robert Datsko made the motion, adding the fluoride would continue until we have more information.

Helen M. Hawkey, executive director of the Pennsylvania Coalition for Oral Health, told authority members the benefits of fluoride have been proven for decades.

Any studies showing adverse effects were conducted in unregulated areas where there was too much fluoride added, she said.

You have to look at the studies, Hawkey said.

You cant just read the headlines that come across social media. Too much of anything is not a good thing.

Woo said he was shocked the authority voted to remove the fluoride without consulting area dentists.

Woo said he has patients from other areas who do not get fluoride in their water.

I look at it now, and what a marked difference, Woo said.

It is such a benefit we provide in Ebensburg.

The authority last month voted to remove the fluoride after Greater Johnstown Water Authority took the...

14:50

Publisher issues first retractions for fake peer review, starts new checking policy "IndyWatch Feed Health"

The publisher Frontiers has retracted four papers in three of its journals after discovering they had been accepted with fake peer reviews. The problem of fake reviews has been on the research communitys radar since at least 2014, and several major publishersincluding Springer, SAGE and BioMed Centralhave retracted hundreds of papers accepted via fake peer []

The post Publisher issues first retractions for fake peer review, starts new checking policy appeared first on Retraction Watch.

14:16

Lets talk about vaccines Event Taken Down After Massive Backlash "IndyWatch Feed Health"

In Australia, freedom of speech is no longer something residents should take for granted, particularly when it comes to the vaccine movement. Australia has been reduced to draconian positions when it comes to diversities in...

The post Lets talk about vaccines Event Taken Down After Massive Backlash appeared first on Vaxxter.

14:05

On Vaccines, Adjuvants and Autoimmunity "IndyWatch Feed Health"

Immunologists survey the research and its not reassuring

Add one more item to the growing stack of published medical literature linking vaccines to the current explosion of autoimmune diseases from skin afflictions to neurological disorders. A paper published in October 2015, the journal Pharmacological Research is an international team of immunologists roundup of current findings on vaccine-induced disease -- and their conclusions are in sharp contrast to public healths safe and effective mantra that denies any such connection.

13:00

We did Transcranial Magnetic Stimulation for My Son with Autism and This is What Happened "IndyWatch Feed Health"

November 21, 2017 I have been following the results of individualized transcranial magnetic stimulation (iTMS) and similar treatments for quite some time. I knew I wanted to try it for my son Harry, but I wanted to wait until I Continue reading

The post We did Transcranial Magnetic Stimulation for My Son with Autism and This is What Happened appeared first on The Thinking Moms' Revolution.

12:26

Cannabis Can End The Use of Prescription Pain Killers "IndyWatch Feed Health"

Opioid prescriptions have jumped 300 percent in the last decade and they are the most commonly prescribed drugs on the market. They are the most dangerous and addictive drugs that often lose effectiveness with long-term use. Now a new study conducted by researchers at The University of New Mexico, involving medical cannabis and prescription opioid use among chronic pain patients, found a distinct connection between having the ability to use cannabis and significant reductions in opioid use.

12:04

Dog Flu Pet Threat Campaign Promotes Merck Vaccine "IndyWatch Feed Health"

AND YOUR LITTLE DOG TOO!!!!!!! Good grief, Snoopy! Merck is now trying to convince you that your dog is in grave danger from the flu and you should be a responsible pet owner and get your dog vaccinated. Dog flu....

12:03

Army Lifts Ban on Waivers for Recruits With Mental Health Issues "IndyWatch Feed Health"

From USA Today: The Army will now allow recruits with a history of self-harm, bipolar disorder, depression, and drug and alcohol abuse to seek waivers to join the service.

Article

12:02

The Problem With Hospitalizing Opioid Addicts Against Their Will "IndyWatch Feed Health"

From The Washington Post: In Massachusetts, which has one of the highest rates of opioid deaths nationally, addiction-related civil commitments have doubled in the past decade. However, civil commitment poses a number of ethical issues, and there is no evidence that it is effective in treating addiction.

Those who believe that civil commitment is being overused say opioid use is not reason enough to take away a persons liberty. Others contend that people should only be held for shorter periods of time. Still others reject any application of involuntary treatment on the view that if a person chooses to misuse opioids, and is not a danger to anyone else or to civil order, he or she should bear the consequences of that decision.

Article

12:01

No More, We Have a CounselorLets Get Real "IndyWatch Feed Health"

In this piece for Medium, Karen Kilbane critiques the way the foundational theories of psychology ingrain children and adolescents with self-doubt and self-criticism.

Our psychological theories have come up with an arbitrary template for how the most perfectly normal child in the world should think, emote, and behave. This perfectly normal child is as mythical as Santa Clause, and exists nowhere in nature. Nonetheless we dangle this idealized child in front of our real children and teach them to aspire to be like him. We constantly measure our real children up to this ideal and let them know when they are falling short or surpassing. This causes extreme personality confusion and there is no other choice but for our children to grow up with crippling self doubt or grandiosity. We give them no choice but to perceive themselves as less than or greater than. Neither choice makes for healthy, happy, civil children.

It is no wonder many people grow up to be adults with no clue as to where they end and other people begin. A child who is treated as an empty vessel adults are trying to turn into their vision of what they think he should be is objectified his whole life. The natural outcome is for the child to grow up and objectify other people. Physical, mental, and sexual abuse flourishes in this culture of objectification. If we want to minimize abuse in our culture, we need to start raising our children much differently than we do now.

12:00

How Do We Prevent Loneliness? "IndyWatch Feed Health"

Photo Credit: "Lonely," by Maykel Stone (Flickr)

09:00

The Death of Expertise "IndyWatch Feed Health"

In Tom Nichols' new book, The Death of Expertise, he explains how a misguided intellectual egalitarianism is harming our ability to assess the truth and solve problems, and discusses some of the responsible factors and possible long-term consequences.

07:00

EPA Refuses to Ban Neurotoxic Pesticide Found in 87 Percent of Newborns "IndyWatch Feed Health"

By Dr. Mercola

Exposure to pesticides, herbicides and insecticides has dramatically increased since the introduction of genetically engineered (GE) crops. Urine output of glyphosate, the active ingredient in the herbicide Roundup, shot up by more than 1,200 percent between 1993 and 2016.1 Unfortunately, glyphosate is not the only chemical of concern.

Chlorpyrifos (sold under the trade name Lorsban) an organophosphate insecticide known to disrupt brain development and cause brain damage, neurological abnormalities, reduced IQ and aggressiveness in children is another.2 ,3 In adults, the chemical has been linked to Parkinson's disease4,5 and lung cancer.6

Chlorpyrifos has been in use since 1965, and is commonly used on staple crops such as wheat and corn, as well as fruits and vegetables, including nonorganic citrus, apples, cherries, strawberries, broccoli, cauliflower and dozens of others. Since the chemical has a half-life of several months and can remain on sprayed foods for up to several weeks,7 nonorganic foods are a major source of exposure.

Importantly, nonorganic, non-grass fed meats are likely to be loaded with this chemical, since conventional feed consists primarily of genetically and/or conventionally-raised grains such as corn. This is yet another reason to make sure you feed your family grass fed meats and animal products, especially your young children. Chlorpyrifos is also a commonly found water contaminant, and has even been found in indoor air.8

Children experience greater exposure to chemicals pound-for-pound than adults, and have an immature and porous blo...

GMO Apples Arriving at Grocery Stores "IndyWatch Feed Health"

By Dr. Mercola

Apples genetically engineered to resist browning when sliced or bruised are on their way to about 400 grocery stores in the U.S. Midwest. Developed by Okanagan Specialty Fruits, the apples are engineered to suppress the production of the enzyme polyphenol oxidase (PPO) that causes browning. The first two varieties of the so-named Arctic Apple Arctic Golden and Arctic Granny were deregulated by the U.S. Department of Agriculture in 2015. A third variety, Arctic Fuji, joined the mix in 2016.1

Their arrival in stores is noteworthy for a number of reasons, the first being that this is the first Genetically modified organism (GMO) designed to have a perceived benefit for consumers. While people have been consuming genetically engineered (GE) foods for some time often without knowing, since labels arent required the GE products were designed to appeal to farmers.

For instance, Monsanto recently released Roundup Ready Xtend cotton and soybean seeds, designed to tolerate both Roundup and dicamba herbicides. Consumers wouldnt go seeking out this type of soybean, but rather consume it by default, because its planted by farmers. This is changing with the release of GE Arctic Apples, which could prompt people to seek out the non-browning apples by name.

Arctic Apples to Serve as a Bellwether for Consumer-Geared GE Foods

Many companies dabbling in GMOs have their eyes on Arctic Apples, waiting to see if consumers accept or reject them. If the apple sells, it will pave the way for others, Yinong Yang, a plant pathologist at Pennsylvania State University in University Park, told Nature. He is among those keeping watch on the new apples, as he created a GE mushroom that resists browning, using CRISPR technology.2

Others waiting in the wings include Finless Foods, which is working on creating Bluefin-tuna fillets made from fish stem cells, and the creators of meatless burgers made from GE yeast. As for Okanagans GE apples, The purpose of Arctic apples is definitely to promote healthy eating, boost apple consumption and reduce food waste, no matter what your age, income or any other factor, the companys president, Neal Carter, told Bloomberg....

Do We Really Need Opioids for Pain? "IndyWatch Feed Health"

By Dr. Mercola

The U.S. is in the midst of an opioid crisis, with more than 91 Americans fatally overdosing on the powerful drugs every day.1 The statistic includes prescription opioids, heroin and fentanyl, but many of the deaths stem from prescription drug use. In fact, of the more than 33,000 Americans killed by opioids in 2015, nearly half of them involved a prescription for the drugs.2 Even the U.S. National Institute on Drug Abuse (NIDA) states:3

Fast-forward about two decades later, and it was estimated that, in 2015, 2 million Americans suffered from substance use disorders related to prescription opioid pain relievers.4

The U.S. Centers for Disease Control and Prevention (CDC) also highlights the fact that overdoses from prescription opioids, in particular, "are a driving factor in the 15-year increase in opioid overdose deaths," noting, "The amount of prescription opioids sold to pharmacies, hospitals, and doctors' offices nearly quadrupled from 1999 to 2010, yet there had not been an overall change in the amount of pain that Americans reported."5

Prescription opioids are considered standard care for treating severe pain following surgery or injury or due to illnesses such as cancer, although they're now increasingly prescribed for many types of pain, including chronic back pain or pain from osteoarthritis. Even in the former case, however, research is now questioning whether the dangerous drugs work better than safer options.

Non-Opioid Pain Relievers Work Just as Well to Treat Pain in ER Patients

If a person comes to the emergency room with severe acute pain, most physicians would prescribe them an opioid to relieve pain. Research published in the Journal of the American Medical Association (JAMA) suggests, howe...

06:48

Low-level red LED light inhibits hyperkeratinization and inflammation induced by unsaturated fatty acid in an in vitro model mimicking acne. "IndyWatch Feed Health"

PMID:  Lasers Surg Med. 2017 Nov 2. Epub 2017 Nov 2. PMID: 29095531 Abstract Title:  Low-level red LED light inhibits hyperkeratinization and inflammation induced by unsaturated fatty acid in an in vitro model mimicking acne. Abstract:  BACKGROUND AND OBJECTIVE: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous units (PSU), associated with increased sebum production, abnormal follicular keratinization (hyperkeratinization), follicular overgrowth of Propionibacterium acnes (P. acnes), and increased inflammatory mediator release. Light therapy has attracted medical interests as a safe alternative treatment for acne. Both blue and red light therapies at high doses>10J/cm(2) have demonstrated marked effects on inflammatory acne lesions. However, few studies have investigated the effects of lower doses of light. The aim of this study is to investigate the biological effects of lower doses of red light at 0.2-1.2J/cm(2) for acne using an in vitro model previously developed to mimic the inflammation and hyperkeratinization observed clinically in acne.MATERIALS AND METHODS: Human epidermal equivalents were topically exposed to an unsaturated fatty acid, oleic acid (OA), followed by red light-emitting diode (LED) light treatments (light-plus-OA treatments). Endpoints evaluated included the proinflammatory cytokine IL-1, epidermal barrier integrity, as measured by transepithelial electrical resistance (TEER), and stratum corneum (SC) thickness to monitor hyperkeratinization.RESULTS: OA-induced IL-1 release was significantly (P

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06:27

Oleuropein treatment against cisplatin-induced toxicity improves the function of blood cells and helps them to survive. "IndyWatch Feed Health"

PMID:  Indian J Hematol Blood Transfus. 2017 Sep ;33(3):348-354. Epub 2016 Aug 16. PMID: 28824236 Abstract Title:  Oleuropein Ameliorates Cisplatin-induced Hematological Damages Via Restraining Oxidative Stress and DNA Injury. Abstract:  The prevalence of cancer, in the world is increasing steadily. Despite intense research efforts, no approved therapy is yet available. Cisplatin is a chemotherapeutic drug but induces acute tissue injury. Oleuropein (OLE) is a major phenolic compound and used as a possible natural antioxidant, antimicrobial, and anticancer agent. We hypothesized that antioxidant activity of OLE may decrease cisplatin-induced oxidative stress and prevent to the development of chemotherapeutic complications including abnormality in hematological condition. Male Sprague Dawley rats were used in the experiments. Rats were randomly assigned to one of eight groups: control group; group treated with i.p. injection in a single dose of 7 mg/kg/day cisplatin; groups treated with 50, 100 and 200 mg/kg/day OLE (i.p.); and groups treated with OLE for 3 days starting at 24 h following cisplatin injection. First, hematological assessment was appreciated between control and experimental groups. Second, total oxidative stress (TOS) andtotal antioxidant capacity (TAC) levels of blood were measured by biochemical studies. In addition to this, oxidative DNA damage was determined by measuring as increases in 8-hydroxy-deoxyguanosine (8-OH-dG) adducts. The treatment with cisplatin elevated the TOS and 8-OH-dG levels that were then reversed by OLE. Reductions in antioxidant capacity with respect to corresponding controls were also restored by OLE treatment. These findings suggest that the OLE treatment against cisplatin-induced toxicity improves the function of blood cells and helps them to survive in the belligerent environmentcreated by free radicals.

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06:23

Oleuropein inhibits the cytotoxicity induced by amylin amyloids, a hallmark feature of type 2 diabetes. "IndyWatch Feed Health"

PMID:  Biochemistry. 2017 Sep 26 ;56(38):5035-5039. Epub 2017 Sep 13. PMID: 28829122 Abstract Title:  Olive Component Oleuropein Promotes-Cell Insulin Secretion and Protects -Cells from Amylin Amyloid-Induced Cytotoxicity. Abstract:  Oleuropein, a natural product derived from olive leaves, has reported anti-diabetic functions. However, detailed molecular mechanisms for how it affects-cell functions remain poorly understood. Here, we present evidence that oleuropein promotes glucose-stimulated insulin secretion (GSIS) in -cells. The effect is dose-dependent and stimulates the ERK/MAPK signaling pathway. We further demonstrated that oleuropein inhibits the cytotoxicity induced by amylin amyloids, a hallmark feature of type 2 diabetes. We demonstrated that these dual functions are structure-specific: we identified the 3-hydroxytyrosol moiety of oleuropein as the main functional entity responsible for amyloid inhibition, but the novel GSIS function requires the entire structure scaffold of the molecule.

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06:18

Oleuropein might be a potential useful therapeutic intervention for PTSD. "IndyWatch Feed Health"

PMID:  J Nat Med. 2017 Sep 7. Epub 2017 Sep 7. PMID: 28884427 Abstract Title:  Effect of oleuropein on cognitive deficits and changes in hippocampal brain-derived neurotrophic factor and cytokine expression in a rat model of post-traumatic stress disorder. Abstract:  Post-traumatic stress disorder (PTSD) is a condition that develops after an individual has experienced a major trauma. This psychopathological response to traumatic stressors induces learning and memory deficits in rats. Oleuropein (OLE), a major compound in olive leaves, has been reported to possess several pharmacological properties, including anti-cancer, anti-diabetic, anti-atherosclerotic and neuroprotective activities. However, the cognitive effects of OLE and its mechanism of action have remained unclear in PTSD. In this study, we examined whether OLE improved spatial cognitive impairment induced in rats following single prolonged stress (SPS), an animal model of PTSD. Male rats were treated intraperitoneally (i.p.) with vehicle or various doses of OLE for 14 consecutive days after the SPS procedure. The SPS procedure resulted in cognitive impairment in the object recognition task and the Morris water maze test, which was reversed by OLE (100 mg/kg, i.p). Additionally, as assessed by immunohistochemistry and reverse transcription-polymerase chain reaction analysis, the administration of OLE significantly alleviated memory-associated decreases in the levels of brain-derived neurotrophic factor and cAMP response element-binding protein and mRNA in the hippocampus. Together, these findings suggest that OLE attenuated SPS-induced cognitive impairment significantly by inhibiting the expression of pro-inflammatory mediators in the rat brain. Thus, OLE reversed several behavioral impairments triggered by the traumatic stress of SPS andmight be a potential useful therapeutic intervention for PTSD.

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06:13

Oleuropein is a promising novel natural source for the prevention of serious kidney damage in current chemotherapies. "IndyWatch Feed Health"

PMID:  J Food Drug Anal. 2017 Apr ;25(2):447-459. Epub 2016 Aug 2. PMID: 28911689 Abstract Title:  Effect of oleuropein against chemotherapy drug-induced histological changes, oxidative stress, and DNA damages in rat kidney injury. Abstract:  Cisplatin-based chemotherapy is responsible for a large number of renal failures, and it is still associated with high rates of mortality today. Oleuropein (OLE) presents a plethora of pharmacological beneficial properties. In this study we investigated whether OLE could provide sufficient protection against cisplatin-induced nephrotoxicity. With this aim, Sprague-Dawley rats were divided into eight groups: control; 7 mg/kg/d cisplatin, 50 mg/kg, 100 mg/kg, and 200 mg/kg OLE; and treatment with OLE for 3 days starting at 24 hours following cisplatin injection. After exposure to the chemotherapy agent and OLE, oxidative DNA damage was quantitated in the renal tissue of experimental animals by measuring theamount of 8-hydroxy-2'-deoxyguanosine (8-OHdG) adducts. Malondialdehyde (MDA) level, total oxidative stress (TOS), and total antioxidant status (TAS) were assessed to determine the oxidative injury in kidney cells. The histology of the kidney was examined using four different staining methods: hematoxylin-eosin (H&E), periodic acid Schiff (PAS), Masson trichrome, and amyloid. In addition, the blood urea nitrogen (BUN), uric acid (UA), and creatinine (CRE) levels were established. Our experimental data showed that tissue 8-OHdG levels were significantly higher in the cisplatin group when compared to the control group. The glomerular cells were sensitive to cisplatin as tubular cells. In addition, treatment with cisplatin elevated the levels of BUN, UA, CRE, and TOS, but lowered the level of TAS compared to the control group. The OLE therapy modulated oxidative stress in order to restore normal kidney function and reduced the formation of 8-OHdG induced by cisplatin. Furthermore, the OLE treatment significantly reduced pathological findings in renal tissue. We demonstrate for the first time that OLE presents significant cytoprotective properties against cisplatin-induced genotoxicity by restoring the antioxidant system of the renal tissue. According to our findings, OLE is a promising novel natural source for the prevention of serious kidney damage in current chemotherapies.

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03:33

Oleuropein has the potential to be a therapeutic drug for lung cancer treatment. "IndyWatch Feed Health"

PMID:  Biomed Pharmacother. 2017 Nov ;95:1425-1435. Epub 2017 Sep 21. PMID: 28946190 Abstract Title:  P38 MAP kinase is involved in oleuropein-induced apoptosis in A549 cells by a mitochondrial apoptotic cascade. Abstract:  Lung cancer is one of malignant tumors that cause great threats to human health, which causes the fastest growing morbidity and mortality. Oleuropein as natural production exerts anticancer effects in several cancer cells. In the study, we investigated apoptotic effect of oleuropein on A549 cells and the underlying mechanisms. Oleuropein markedly decreased cell viability in A549 cells by resulting in G2/M phase arrest, but failed to decreased cell viability in BEAS-2B cells significantly. Apoptosis by oleuropein was confirmed by apoptotic morphology, accumulation in a sub-G1 peak, nucleus fragmentation and cleavage of PARP. Dose-dependent elevation in p-p38MAPK and p-ATF-2 was observed whereas apparent changes could not be observed in p-JNK and p-c-Jun, showing activation of p38MAPK but not JNK. Interestingly, ERK1/2 appeared to be constant while p-ERK1/2 was reduced dose-dependently. Oleuropein caused decrease in mitochondrial membrane potential, increase in Bax/Bcl- 2 ratio, release of mitochondrial cytochrome c and activation of caspase-9 and caspase-3, implying that mitochondrial apoptotic pathway was activated. Additionally, oleuropein-induced apoptosis was dramatically attenuated by Z-VAD-FMK (caspase inhibitor). The p38MAPK inhibitor prevented production of apoptotic bodies and reduced expressions of cleaved-PARP, p-P38, p-ATF-2 and release of cytochrome c. Taken together, these results demonstrated p38MAPK signaling pathway mediated oleuropein-induced apoptosis via mitochondrial apoptotic cascade in A549 cells. Oleuropein has the potential to be a therapeutic drug for lung cancer treatment.

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03:29

These findings provide the evidence to develop oleuropein as a potential therapeutic agent for patients with osteoarthritis. "IndyWatch Feed Health"

PMID:  Food Funct. 2017 Oct 18 ;8(10):3737-3744. PMID: 28952621 Abstract Title:  Oleuropein inhibits the IL-1-induced expression of inflammatory mediators by suppressing the activation of NF-B and MAPKs in human osteoarthritis chondrocytes. Abstract:  Osteoarthritis (OA) is the most common form of joint disease and is widespread in the elderly population and is characterized by erosion of articular cartilage, subchondral bone sclerosis and synovitis. Oleuropein (OL), a secoiridoid, is considered as the most prevalent phenolic component in olive leaves and seeds, pulp and peel of unripe olives and has been shown to have potent anti-inflammatory effects. However, its effects on OA have not been clearly elucidated. This study aimed to assess the effect of OL on human OA chondrocytes. Human OA chondrocytes were pretreated with OL (10, 50 and 100M) for 2 h and subsequently stimulated with IL-1 for 24 h. The production of NO, PGE2, MMP-1, MMP-13, and ADAMTS-5 was evaluated by the Griess reaction and ELISA assays. The messenger RNA (mRNA) expression of COX-2, iNOS, MMP-1, MMP13, ADAMTS-5, aggrecan, and collagen-II was measured by using real-time PCR. The protein expressions of COX-2, iNOS, p65, IB-, JNK, p-JNK, ERK, p-ERK, p38, and p-p38 were tested by using western blot. We found that OL significantly inhibited the IL-1-induced production of NO and PGE2; expression of COX-2, iNOS, MMP-1, MMP-13, and ADAMTS-5; and degradationof aggrecan and collagen-II. Furthermore, OL dramatically suppressed IL-1-stimulated NF-B and MAPK activation. Immunofluorescence staining demonstrated that OL could suppress IL-1-induced phosphorylation of p65 nuclear translocation. These results indicate that the therapeutic effect of OL onOA is accomplished through the inhibition of both NF-B and MAPK signaling pathways. Altogether, our findings provide the evidence to develop OL as a potential therapeutic agent for patients with OA.

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03:24

Olive and its derivatives show potential in preventing cartilage damage due to osteoarthritis. "IndyWatch Feed Health"

PMID:  Nutrients. 2017 Sep 26 ;9(10). Epub 2017 Sep 26. PMID: 28954409 Abstract Title:  Therapeutic Effects of Olive and Its Derivatives on Osteoarthritis: From Bench to Bedside. Abstract:  Osteoarthritis is a major cause of morbidity among the elderly worldwide. It is a disease characterized by localized inflammation of the joint and destruction of cartilage, leading to loss of function. Impaired chondrocyte repair mechanisms, due to inflammation, oxidative stress and autophagy, play important roles in the pathogenesis of osteoarthritis. Olive and its derivatives, which possess anti-inflammatory, antioxidant and autophagy-enhancing activities, are suitable candidates for therapeutic interventions for osteoarthritis. This review aimed to summarize the current evidence on the effects of olive and its derivatives, on osteoarthritis and chondrocytes. The literature on animal and human studies has demonstrated a beneficial effect of olive and its derivatives on the progression of osteoarthritis. In vitro studies have suggested that the augmentation of autophagy (though sirtuin-1) and suppression of inflammation by olive polyphenols could contribute to the chondroprotective effects of olive polyphenols. More research and well-planned clinical trials are required to justify the use of olive-based treatment in osteoarthritis.

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03:13

This review provides an updated vision of the beneficial properties of olive oil in counteracting both acute and chronic neurodegenerative diseases. "IndyWatch Feed Health"

PMID:  Int J Mol Sci. 2017 Oct 25 ;18(11). Epub 2017 Oct 25. PMID: 29068387 Abstract Title:  Bioactivity of Olive Oil Phenols in Neuroprotection. Abstract:  Neurological disorders such as stroke, Alzheimer's and Parkinson's diseases are associated with high morbidity and mortality, and few or no effective options are available for their treatment. These disorders share common pathological characteristics like the induction of oxidative stress, abnormal protein aggregation, perturbed Ca(2+) homeostasis, excitotoxicity, inflammation and apoptosis. A large body of evidence supports the beneficial effects of the Mediterranean diet in preventing neurodegeneration. As the Mediterranean diet is characterized by a high consumption of extra-virgin olive oil it has been hypothesized that olive oil, and in particular its phenols, could be responsible for the beneficial effect of the Mediterranean diet. This review provides an updated vision of the beneficial properties of olive oil and olive oil phenols in preventing/counteracting both acute and chronic neurodegenerative diseases.

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03:05

The modulation of the senescence-associated inflammatory phenotype might be an important mechanism underlying the beneficial effects of olive oil. "IndyWatch Feed Health"

PMID:  Int J Mol Sci. 2017 Oct 30 ;18(11). Epub 2017 Oct 30. PMID: 29084133 Abstract Title:  Modulation of the Senescence-Associated Inflammatory Phenotype in Human Fibroblasts by Olive Phenols. Abstract:  Senescent cells display an increase in the secretion of growth factors, inflammatory cytokines and proteolytic enzymes, termed the"senescence-associated-secretory-phenotype"(SASP), playing a major role in many age-related diseases. The phenolic compounds present in extra-virgin olive oil are inhibitors of oxidative damage and have been reported to play a protective role in inflammation-related diseases. Particularly, hydroxytyrosol and oleuropein are the most abundant and more extensively studied. Pre-senescent human lung (MRC5) and neonatal human dermal (NHDF) fibroblasts were used as cellular model to evaluate the effect of chronic (4-6 weeks) treatment with 1M hydroxytyrosol (HT) or 10 M oleuropein aglycone (OLE) on senescence/inflammation markers. Both phenols were effective in reducing -galactosidase-positive cell number and p16 protein expression. In addition, senescence/inflammation markers such as IL-6 and metalloprotease secretion, and Ciclooxigenase type 2 (COX-2) and -smooth-actin levels were reduced by phenol treatments. In NHDF, COX-2 expression, Nuclear Factor -light-chain-enhancer of activated B cells (NFB) protein level and nuclear localization were augmented with culture senescence and decreased by OLE and HT treatment. Furthermore, the inflammatory effect of Tumor Necrosis Factor (TNF) exposure was almost completely abolished in OLE- and HT-pre-treated NHDF. Thus, the modulation of the senescence-associated inflammatory phenotype might be an important mechanism underlying the beneficial effects of olive oil phenols.

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02:57

Oleuropein protects intracerebral hemorrhage-induced disruption of blood-brain barrier through alleviation of oxidative stress. "IndyWatch Feed Health"

PMID:  Pharmacol Rep. 2017 May 11 ;69(6):1206-1212. Epub 2017 May 11. PMID: 29128801 Abstract Title:  Oleuropein protects intracerebral hemorrhage-induced disruption of blood-brain barrier through alleviation of oxidative stress. Abstract:  BACKGROUND: Intracerebral haemorrhage (ICH) as a devastating form of stroke has remained a public health threat due to lack of FDA-approved therapy. Oxidative stress originated from blood cell degradation products plays a crucial role in the ICH pathogenesis. In this study we evaluated oleuropein, a potent natural antioxidant from olive, in a well-established rat ICH model from overall symptoms to detailed molecular mechanism.METHODS: ICH model was established by collagenase injection to the brain of rats, which were randomly divided into groups with vehicle mock treatment, followed by treatment with different doses of oleuropein via daily intraperitoneal injection post-ICH for 3days. The overall neurological deficit, brain edema level and blood-brain barrier (BBB) integrity were then measured in different treatment groups. To understand the protection mechanism of oleuropein in ICH, BBB structural components ZO-1 and occludin, oxidative stress and MAPK signalling pathways were also examined.RESULTS: Oleuropein treatment showed overall alleviation of ICH-associated neurological deficit and brain edema in a dose dependent manner. Consistently, it could preserve the BBB structure and attenuate oxidative stress as well as ICH-induced MAPK activation in brain tissue.CONCLUSION: Our study suggests oleuropein could be used as a promising therapeutic agent for ICH.

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02:51

Extra virgin olive oil has liver protective effects. "IndyWatch Feed Health"

PMID:  Endocr Metab Immune Disord Drug Targets. 2017 Nov 14. Epub 2017 Nov 14. PMID: 29141573 Abstract Title:  Liver protective effects of extra virgin olive oil: interaction between its chemical composition and the cell-signaling pathways involved in protection. Abstract:  BACKGROUND AND OBJECTIVE: The liver is an organ susceptible to a multitude of injuries that causes liver damage, like steatosis, non-alcoholic steatohepatitis, cirrhosis, hepatocellular carcinoma, and ischemia-reperfusion injury. Extra virgin olive oil (EVOO), presents several protective effects on the liver, reducing hepatic steatosis, hepatocyte ballooning, fibrogenesis, preventing lipid peroxidation, among other effects. Due to its high levels of monounsaturated fatty acids, mainly oleic acid and phenolic compounds, such as hydroxytyrosol and oleuropein, EVOO is able to participate in the activation of different signaling pathways in the hepatocytes involved in the prevention of inflammation, oxidative stress, endoplasmic reticulum stress, mitochondrial dysfunction, and insulin resistance, allowing the prevention or resolution of liver damage. The aim of this work is to offer an update of the molecular effects of EVOO in the liver and its protective properties to prevent the establishment of liver damage through the regulation of different cell-signaling pathways.METHODS: Searches that considered the effects of EVOO in in vivo and in vitro models, whit emphasis in the molecular mechanism of liver tissue damage and prevention and/or treatment of steatosis, steatohepatitis, cirrhosis, hepatocellular carcinoma, and ischemia-reperfusion injury.CONCLUSION: The most relevant molecular effects of EVOO involved in the prevention or resolution of liver damage are: (i) activation of the nuclear transcription factor erythroid-derived 2-like 2 (Nfr2), inducing the cellular antioxidant response; (ii) inactivation of the nuclear transcription factor-B (NF-B), preventing the cellular inflammatory response; and (iii) inhibition of the PERK pathway, preventing endoplasmic reticulum stress, autophagy, and lipogenic response.

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02:47

Oleuropein is responsible for the major anti-Inflammatory effects of olive leaf extract. "IndyWatch Feed Health"

PMID:  J Med Food. 2017 Nov 3. Epub 2017 Nov 3. PMID: 29099642 Abstract Title:  Oleuropein Is Responsible for the Major Anti-Inflammatory Effects of Olive Leaf Extract. Abstract:  Olive leaves are rich in polyphenolic compounds that are known to have antioxidant, antimicrobial, and anti-inflammatory activities. Therefore, olive leaf extract (OLE) is considered as a natural supplement. In this study we evaluated the antibacterial and the anti-inflammatory effect of OLE and its individual phenolic components in vitro. Polymorphonuclear cells (PMNCs) were isolated from the whole blood using Histopaque solution and cultured in RPMI-enriched medium. Tumor necrosis factor (TNF) level was determined by ELISA after 24h of lipopolysaccharide stimulation. The antibacterial activity of OLE was determined by well diffusion assay. We found a significant decrease in TNF secretion level in PMNCs culture treated with OLE. Oleuropein is the only OLE component that hasshown anti-inflammatory effects at a concentration of 20g/mL. Furthermore, OLE exhibited antibacterial activity against some gram positive bacterial strains; however, gram negative bacterial strains were resistant to OLE. Downregulation of TNF secretion in PMNCs culture in response to OLE treatment indicates that this polyphenol-rich extract has an anti-inflammatory effect, and oleuropein is the major OLE component responsible for this effect. The antibacterial activity of OLE is limited to gram positive bacteria.

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02:41

Olive biophenols potentially serve as agents for the prevention of neurodegenerative diseases. "IndyWatch Feed Health"

PMID:  Molecules. 2017 Oct 29 ;22(11). Epub 2017 Oct 29. PMID: 29109370 Abstract Title:  Olive (Olea europaea L.) Biophenols: A Nutriceutical against Oxidative Stress in SH-SY5Y Cells. Abstract:  Plant biophenols have been shown to be effective in the modulation of Alzheimer's disease (AD) pathology resulting from free radical-induced oxidative stress and imbalance of the redox chemistry of transition metal ions (e.g., iron and copper). On the basis of earlier reported pharmacological activities, olive biophenols would also be expected to have anti-Alzheimer's activity. In the present study, the antioxidant activity of individual olive biophenols (viz. caffeic acid, hydroxytyrosol, oleuropein, verbascoside, quercetin, rutin and luteolin) were evaluated using superoxide radical scavenging activity (SOR), hydrogen peroxide (HO) scavenging activity, and ferric reducing ability of plasma (FRAP) assays. The identification and antioxidant activities in four commercial olive extracts-Olive leaf extract(TM) (OLE), Olive fruit extract(TM) (OFE), Hydroxytyrosol Extreme(TM) (HTE), and Olivenol plus(TM) (OLP)-were evaluatedusing an on-line HPLC-ABTS(+) assay, and HPLC-DAD-MS analysis. Oleuropein and hydroxytyrosol were the predominant biophenols in all the extracts. Among the single compounds examined, quercetin (EC50: 93.97 M) and verbascoside (EC50: 0.66 mM) were the most potent SOR and HO scavengers respectively. However, OLE and HTE were the highest SOR (EC50: 1.89 g/mL) and HO (EC50: 115.8 g/mL) scavengers among the biophenol extracts. The neuroprotection of the biophenols was evaluated against HO-induced oxidative stress and copper (Cu)-induced toxicity in neuroblastoma (SH-SY5Y) cells. The highest neuroprotection values (98% and 92%) against HO-induced and Cu-induced toxicities were shown by the commercial extract HTE(TM). These were followed by the individual biophenols, caffeic acid (77% and 64%) and verbascoside (71% and 72%). Our results suggest that olive biophenols potentially serve as agents for the prevention of neurodegenerative diseases such as AD, and other neurodegenerative ailments that are caused by oxidative stress.

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02:28

Olive leaf extracts act as modulators of the human immune response. "IndyWatch Feed Health"

PMID:  Endocr Metab Immune Disord Drug Targets. 2017 Nov 15. Epub 2017 Nov 15. PMID: 29149822 Abstract Title:  Olive Leaf Extracts Act as Modulators of the Human Immune Response. Abstract:  BACKGROUND: Olive tree leaves have been used in the Mediterranean area as traditional medicine in virtue of their healthy effects. Olive leaf extracts (OLEs) contain higher amounts of polyphenols than those detected in the extra virgin olive oil and fruit. Several lines of evidence support the cardioprotective, anti-oxidant and anti-inflammatory activities exerted by OLEs.METHODS: Peripheral blood mononuclear cells (PBMCs) from twenty-five healthy donors were cultured in the presence of 3g of two OLE extracts, extract A (resuspended in water) and extract B (resuspended in 70% ethanol). After harvesting, cell pellets were used for cytofluorimetric phenotyping, while supernatants were assayed for cytokine release by means of ELISA. Furthermore, in the same supernatants nitric oxide(NO) content was determined.RESULTS: Both extracts, but especially extract A, increased absolute numbers of CD8+ and natural killer (NK) cells. In addition, an increased production of interferon-g by both extracts as an expression of T helper (h)1 activation was observed. Finally, both extracts enhanced NO release.CONCLUSION: OLEs, and mostly extract A, are able to in vitro modify healthy human immune response by increasing IFN-g production which seems to be associated to the higher absolute numbers of CD8+ and NK cells and this may suggest a reinforcement of the anti-tumor activity. Furthermore, increased levels of NO may indicate the potential cardioprotective effects exerted by OLEs in virtue of their vasodilation dependent activity. Finally, OLEs are able to maintain the equilibrium between T regulatory cells and Th17 cells as evidenced by unmodified levels of IL-10 and IL-17, respectively. In the light of these results, OLEs are potential therapeutic compounds for the treatment of chronic inflammatory disease, also preventing cardiovascular event outcome.

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02:15

Currently available evidence supports the anti-inflammatory and cardio-protective roles of extra-virgin olive oil. "IndyWatch Feed Health"

PMID:  Endocr Metab Immune Disord Drug Targets. 2017 Nov 15. Epub 2017 Nov 15. PMID: 29149823 Abstract Title:  Olive Oil-related Anti-inflammatory Effects on Atherosclerosis: Potential Clinical Implications. Abstract:  BACKGROUND AND OBJECTIVE: Atherosclerosis is characterized by a chronic low-grade inflammatory process which can result in atherothrombosis and a number of cardiovascular diseases (CVD). It is believed to be caused by multiple processes that involve inflammation and immunity. Mediterranean Diet (MedD) has been discovered to possess anti-inflammatory properties and associated with a reduction in the CVD risk and mortality. Its main component, extra-virgin olive oil (EVOO), is believed to be largely responsible for these effects and therefore, has been investigated in various studies. The present review article aims to summarize the available literature on the anti-inflammatory and cardio-protective effects of EVOO.METHODS: A search based on the key concepts"olive oil","atherosclerosis","inflammation"and"cardiovascular disease"was performed to retrieve relevant studies and articles on the association between the consumption of EVOO and the levels of inflammatory biomarkers as well as CVD incidence and mortality from online databases; Pubmed, Embase and Cochrane Library.RESULTS: Consumption of EVOO is associated with a reduction in inflammatory biomarkers and molecules implicated in atherosclerosis as well as CVD incidence and mortality as well as other complications such as heart failure and atrial fibrillation. Moreover, these anti-inflammatory and cardioprotective effects of EVOO are mostly attributable to its high content of polyphenol molecules.CONCLUSION: Currently available evidence supports the anti-inflammatory and cardio-protective roles of EVOO. However, there is limited amount of available randomized controlled trials especially lacking those investigating the use of EVOO as secondary prevention, heterogeneity of study design, limited generalization to wide population groups, and inability to determine the minimum intake of EVOO required to clinically achieve the anti-inflammatory and cardioprotective effects. Therefore, more high-quality randomized controlled trials still need to be carried out to overcome these challenges to further assess the health benefits of EVOO consumption and potentially translate it into clinical practice as primary or secondary prevention of atherosclerosis-related conditions.

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02:10

Cell Phone Induced Bodiliy Harm How the Bees Can Help "IndyWatch Feed Health"

Cell Phone-Induced Bodily Harm: How The Bees Can Help
2Posted on: Monday, November 20th 2017 at 10:15 am
Written By: Sayer Ji, Founder
This article is copyrighted by GreenMedInfo LLC, 2017

Did you know that your cell phone technically microwaves your brain?  And did you know that natural substances have proven radioprotective properties that can reduce your risk of adverse exposures? 
Cell phones and the communications infrastructure that makes them possible are ubiquitous today, making complete avoidance of their significant radiotoxicy next to impossible.  Plenty of evidence already exists showing that cell phones emit a type of electromagnetic radiation -- in the microwave range -- capable of adversely affecting a wide range of organs, with the nervous system of those exposed perhaps most sensitive to its adverse effects. Below is a sampling of some of their adverse health effects as demonstrated in the biomedical literature:

02:07

Homeopathic intervention was beneficial in subclinical hypothyroidism with or without autoimmune thyroiditis in children. "IndyWatch Feed Health"

PMID:  Homeopathy. 2014 Oct ;103(4):224-31. Epub 2014 Sep 27. PMID: 25439038 Abstract Title:  Efficacy of homeopathic intervention in subclinical hypothyroidism with or without autoimmune thyroiditis in children: an exploratory randomized control study. Abstract:  INTRODUCTION: The decision to treat subclinical hypothyroidism (SCH) with or without autoimmune thyroiditis (AIT) in children, presents a clinical dilemma. This study was undertaken to evaluate the efficacy of individualized homeopathy in these cases.METHODS: The study is an exploratory, randomized, placebo controlled, single blind trial. Out of 5059 school children (06-18 years) screened for thyroid disorders, 537 children had SCH/AIT and 194 consented to participate. Based on primary outcome measures (TSH and/or antiTPOab) three major groups were formed: Group A - SCH + AIT (n = 38; high TSH with antiTPOab+), Group B - AIT (n = 47; normal TSH with antiTPOab+) and Group C - SCH (n = 109; only high TSH) and were further randomized to two subgroups-verum and control. Individualized homeopathy or identical placebo was given to respective subgroup. 162 patients completed 18 months of study.RESULTS: Baseline characteristics were similar in all the subgroups. The post treatment serum TSH (Group A and C) returned to normal limits in 85.94% of verum and 64.29% of controls (p

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02:06

7 Health Benefits of Bee Propolis "IndyWatch Feed Health"

7 Health Benefits of Bee Propolis

Posted on: Monday, November 20th 2017 at 6:30 am
This article is copyrighted by GreenMedInfo LLC, 2017

Bees make more than honey.  They also make a waxy substance called propolis. And this "bee glue" is a powerful health balm.  In fact, studies show it has anti-cancer properties.
Dr. Seema Patel of the Bioinformatics and Medical Informatics Research Center, San Diego State University conducted a comprehensive review of the literature on propolis and cancer.  Dr. Patel found laboratory and animal studies supporting propolis efficacy against cancers of the:
  • Brain
  • Pancreas
  • Head and neck
  • Kidney and bladder
  • Skin
  • Prostate
  • Breast
  • Colon
  • Liver
  • Blood  
Propolis is astoundingly complex and contains as many as 300 active compounds.  These components were found to fight cancer in a variety of ways including:
  • Preventing the growth of new blood vessels to feed cancer cells (anti-angiogenesis)
  • Prevent...

02:00

Homeopathy but integrative medicine could provide different approaches to the treatment of low-grade chronic inflammation. "IndyWatch Feed Health"

PMID:  Med Hypotheses. 2011 May ;76(5):622-6. Epub 2011 Feb 1. PMID: 21277692 Abstract Title:  Low-grade inflammation in chronic diseases: an integrative pathophysiology anticipated by homeopathy? Abstract:  Pro-inflammatory cytokines and their chronic effect - low-grade inflammation - have been associated with diverse chronic conditions. Nonsteroidal anti-inflammatory drugs (NSAIDs) were recently proposed as a treatment strategy. Samuel Hahnemann, the founder of homeopathy, had already hypothesized a systemic and progressive disorder as the cause of many chronic diseases - the Psora theory. He also advised of the consequences of palliative use for chronic diseases, as a contrary effect of the"of the life-preserving principle"could worsen the course of those diseases. The hypotheses presented here are that the main aspects of Hahnemann's Psora theory are supported by current data on the role of pro-inflammatory cytokines and that the use of NSAIDs to treat chronic low-grade inflammation can produce a contrary, rebound effect, as anticipated by Hahnemann. By diverting from the"palliative action-rebound effect"course, not only homeopathy but integrative medicine could provide different approaches to the treatment of low-grade chronic inflammation. Studies assessing inflammatory markers in chronic integrative treatments are recommended.

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01:52

Vaccines and Pregnancy "IndyWatch Feed Health"

Note: I'm at an age where my friends kids are beginning to get married and have their own children. While, the girls' Dad and I will never have grandchildren thanks to autism, such is not the case for most AofA...

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23:45

Help the feathery dinosaur for Thanksgiving please "IndyWatch Feed Health"

The Skeptical Raptor, stalking pseudoscience in the internet jungle.

We are coming up on the Thanksgiving holiday here in the USA, where we all fall asleep watching football and consuming turkey.  And we still have to ask readers out there to help the feathery dinosaur keep the website running for the next few months. Admittedly, the feathery dinosaur is someone offended that one of

Skeptical Raptor

23:37

Mentha arvensis essential oil suppressed airway changes induced by histamine and ovalbumin in experimental animals. "IndyWatch Feed Health"

PMID:  Nat Prod Res. 2017 Apr 7:1-5. Epub 2017 Apr 7. PMID: 28385073 Abstract Title:  Mentha arvensis essential oil suppressed airway changes induced by histamine and ovalbumin in experimental animals. Abstract:  The present investigation aimed to evaluate the activity of the essential oil of Mentha arvensis L. on exogenously induced bronchoconstriction in experimental animals. The anti-asthmatic effect of M. arvensis essential oil (MAEO) was studied using histamine aerosol-induced bronchoconstriction in guinea pigs and ovalbumin (OVA) sensitised albino mice. Treatment with M. arvensis oil significantly (p 

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23:26

Feasibility, tolerability and acceptability of use of the RGN107 powder for chronic wounds were established. "IndyWatch Feed Health"

PMID:  J Wound Care. 2017 Jan 2 ;26(Sup1):S25-S34. PMID: 28105900 Abstract Title:  Feasibility, acceptability, and tolerability of RGN107 in the palliative wound care management of chronic wound symptoms. Abstract:  OBJECTIVE: To assess the feasibility, acceptability and tolerability of RGN107 use, a natural powder blend of Arnica Montana, Calendula Officinalis, Mentha Arvensis and Santalum Album, among hospice patients and their wound caregivers in the palliative wound care management of chronic wound symptoms at end-of-life.METHOD: Data were collected between May 2013 and November 2015. A pilot trial conducted among 50 hospice patients with symptomatic (pain, odour, or exudate) chronic wounds. Caregivers received initial RGN107 protocol training, actively applied the powder to patient wounds for 4-weeks, and completed an 8-week retrospective survey. Feasibility was assessed by measuring process outcomes, including the number and proportion of participants referred, screened eligible, enrolled, withdrawn and successfully completed. Acceptability measures included: a protocol training evaluation, caregiver pre and post self-efficacy ratings, retrospective usability, symptom control management and comparative technique caregiver ratings, and recorded open-ended comments. Tolerability was assessed through a 12-week cumulative review of the study adverse event profile.RESULTS: Feasibility, tolerability and acceptability of use of the RGN107 powder for chronic wounds were established. Recruitment goals were achieved and 92 % of the patients successfully completed the study. 95 % of wound caregivers would recommend the powder for use in this population.CONCLUSION: This study supports the feasibility, acceptability and tolerability of a wound care powder that espouses a multi-symptom palliative comfort care approach for hospice patients with chronic wounds at end-of-life. Further research is needed to establish the efficacy of the powder.

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23:00

The ethanolic extract of L. passerina and goyazensolide can be considered promising agents in the therapeutic of inflammation, hyperuricemia and gout. "IndyWatch Feed Health"

PMID:  J Ethnopharmacol. 2017 Feb 23 ;198:444-450. Epub 2017 Jan 12. PMID: 28089739 Abstract Title:  The influence of seasonality on the content of goyazensolide and on anti-inflammatory and anti-hyperuricemic effects of the ethanolic extract of Lychnophora passerina (Brazilian arnica). Abstract:  ETHNOPHARMACOLOGICAL RELEVANCE: Lychnophora passerina (Mart ex DC) Gardn (Asteraceae), popularly known as Brazilian arnica, is used in Brazilian folk medicine to treat pain, rheumatism, bruises, inflammatory diseases and insect bites.AIM OF THE STUDY: Investigate the influence of the seasons on the anti-inflammatory and anti-hyperuricemic activities of ethanolic extract of L. passerina and the ratio of the goyazensolide content, main chemical constituent of the ethanolic extract, with these activities.MATERIALS AND METHODS: Ethanolic extracts of aerial parts of L. passerina were obtained from seasons: summer (ES), autumn (EA), winter (EW) and spring (EP). The sesquiterpene lactone goyazensolide, major metabolite, was quantified in ES, EA, EW and EP by a developed and validated HPLC-DAD method. The in vivo anti-hyperuricemic and anti-inflammatory effects of the ethanolic extracts from L. passerina and goyazensolide were assayed on experimental model of oxonate-induced hyperuricemia in mice, liver xanthine oxidase (XOD) inhibition and on carrageenan-induced paw edema in mice.RESULTS: HPLC method using aqueous solution of acetic acid 0.01% (v/v) and acetonitrile with acetic acid 0.01% (v/v) as a mobile phase in a gradient system, with coumarin as an internal standard and DAD detection at 270nm was developed. The validation parameters showed linearity in a range within 10.0-150.0g/ml, with intraday and interday precisions a range of 0.61-3.82. The accuracy values of intraday and interday analysis within 87.58-100.95%. EA showed the highest goyazensolide content. From the third to the sixth hour after injection of carrageenan, treatments with all extracts at the dose of 125mg/kg were able to reduce edema. Goyazensolide (10mg/kg) showed significant reduction of paw swelling from the second hour assay. This sesquiterpene lactone was more active than extracts and presented similar effect to indomethacin. Treatments with ES, EA and EP (125mg/kg) and goyazensolide (10mg/kg) reduced serum urate levels compared to hyperuricemic control group and were able to inhibit liver XOD activity. One of the mechanisms by which ES, EA, EP and goyazensolide exercise their anti-hyperuricemic effect is by the inhibition of liver XOD activity. Goyazensolide was identified as the maincompound present in ES, EA, EW and EP and it is shown to be one of the chemical constituents responsible for the anti-inflammatory and anti-hyperuricemic effects of the ethanolic extracts.CONCLUSION: The anti-inflammatory and anti-hyperuric...

22:53

A. montana 1000 K could reduce post-operative blood and seroma collection in women undergoing unilateral total mastectomy. "IndyWatch Feed Health"

PMID:  J Intercult Ethnopharmacol. 2017 Jan-Mar;6(1):1-8. Epub 2017 Jan 3. PMID: 28163953 Abstract Title:  Is there a role for homeopathy in breast cancer surgery? A first randomized clinical trial on treatment with Arnica montana to reduce post-operative seroma and bleeding in patients undergoing total mastectomy. Abstract:  AIM: This study aimed to evaluate the benefits of Arnica montana on post-operative blood loss and seroma production in women undergoing unilateral total mastectomy by administering Arnica Montana 1000 Korsakovian dilution (1000 K).MATERIALS AND METHODS: From 2012 to 2014, 53 women were randomly assigned to A. montana or placebo and were followed up for 5 days. The main end point was the reduction in blood and serum volumes collected in drainages. Secondary end points were duration of drainage, a self-evaluation of pain, and the presence of bruising or hematomas.RESULTS: The per-protocol analysis revealed a lower mean volume of blood and serum collected in drainages with A. montana (-94.40 ml; 95% confidence interval [CI]: 22.48-211.28; P = 0.11). A regression model including treatment, volume collected in the drainage on the day of surgery, and patient weight showed a statistically significant difference in favor of A. montana (-106.28 ml; 95% CI: 9.45-203.11; P = 0.03). Volumes collected on the day of surgery and the following days were significantly lower with A. montana at days 2 (P = 0.033) and 3 (P = 0.0223). Secondary end points have not revealed significant differences.CONCLUSIONS: A. montana 1000 K could reduce post-operative blood and seroma collection in women undergoing unilateral total mastectomy. Larger studies are needed with different dilutions of A. montana to further validate these data.

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22:50

Influenza On And Off The Grid "IndyWatch Feed Health"

Influenza On and Off The Grid Even with modern medical technology, few can avoid the occasional respiratory infection. Viral illnesses like colds and flus are common issues even for those who are in prime physical condition. Human illness involves the respiratory tract more commonly than any other organ system. Influenza is particularly contagious as germ-laden droplets are expelled during coughs and sneezes, entering the nose, mouth, or eyes of others. You can expect influenza viruses to hit your part of

[... Continue Reading]

22:42

At the end of treatment, 81.5% of patients described themselves as symptom free or significantly improved. "IndyWatch Feed Health"

PMID:  Adv Ther. 1999 Mar-Apr;16(2):103-11. PMID: 10539378 Abstract Title:  Efficacy and safety of a fixed-combination homeopathic therapy for sinusitis. Abstract:  The efficacy and safety of a fixed-combination homeopathic medication (Sinusitis PMD) consisting of Lobaria pulmonaria, Luffa operculata, and potassium dichromate were investigated in an open-label practice-based study of 119 male and female patients, 12 to 57 years of age, with clinical signs of acute sinusitis not previously treated. At the first visit, after a mean of 4.1 days of treatment, secretolysis had increased significantly and typical sinusitis symptoms, such as headache, pressure pain at nerve exit points, and irritating cough, were reduced. Ninety-nine patients received only the test medication. Twenty patients were able to discontinue concomitant medication at the first visit. Only one patient needed an antibiotic. The average treatment duration was 2 weeks. At the end of treatment, 81.5% of patients described themselves as symptom free or significantly improved. Adverse drug effects were not reported.

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22:34

Evaluation of anti-inflammatory activity of Calotropis gigantea (AKANDA) in various biological system. "IndyWatch Feed Health"

PMID:  Nepal Med Coll J. 2006 Sep ;8(3):156-61. PMID: 17203820 Abstract Title:  Evaluation of anti-inflammatory activity of Calotropis gigantea (AKANDA) in various biological system. Abstract:  To evaluate the effect of Calotropis G in various experimental animal models. The anti-inflammatory activity was evaluated using carrageenin-induced kaolin -induced rat paw oedema for acute and cotton-pellet granuloma, adjuvant-induced arthritis model for chronic inflammation. Antipyretic activity was carried out using yeast induced pyresis method. Phenylquinone--induced writhing method in mice was used for analgesic activity. Test compounds exhibited variable anti-inflammatory activity and peak activity of the test compounds were reached at 2 h. Alkaloid fraction possesses comparatively high initial anti-inflammatory activity. The residual anti-inflammatory activity of alkaloid fraction of Calotropis G suggest either a greater protein binding nature of the compound there by providing a slow released pool of active drug molecule in the system or non available of possible bioactive metabolites to retain the activity profile relation.

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22:29

Activation of bone marrow cells treated with Canova in vitro. "IndyWatch Feed Health"

PMID:  Cell Biol Int. 2006 Oct ;30(10):808-16. Epub 2006 Jul 7. PMID: 16884931 Abstract Title:  Activation of bone marrow cells treated with Canova in vitro. Abstract:  Canova is a Brazilian complex homeopathic medication produced from Aconitum, Thuya, Bryonia, Lachesis and Arsenicum. Previous studies demonstrated that Canova induces up-regulation in numbers of leukocytes. The bone marrow microenvironment is composed of growth factors, stromal cells, extracellular matrix, and progenitor cells that differentiate into mature blood cells. As it is the major site of blood cell formation, we studied in vitro Canova effects on bone marrow cells of mice. Swiss mouse femurs were dissected, cleaned, and the marrow was flushed. The cells were plated, treated or not, incubated for different times and processed for light, scanning electron, and confocal microscopy, and also flow cytometry. The treatment did not modify the expression of the analyzed surface markers or cytokine production. All microscopy techniques showed that a monocytic lineage (CD11b(+)) and stromal cells (adherent cells) were activated by treatment. Canova also increased cell clusters over adherent cells, suggesting proliferation areas.

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22:23

This paper summarizes homeopathic treatment with snake remedies of cats suffering from eosinophilic granuloma complex. "IndyWatch Feed Health"

PMID:  Homeopathy. 2006 Jan ;95(1):15-9. PMID: 16399250 Abstract Title:  Snake remedies and eosinophilic granuloma complex in cats. Abstract:  Eosinophilic granuloma complex (EGC) is a syndrome occurring in cats, characterized by lesions affecting the skin and the oral cavity. Conventional treatment is mainly symptomatic and may have undesirable side effects. This paper summarizes homeopathic treatment with snake remedies of cats suffering from EGC. Snake remedies were chosen by individual repertorizations and administered in different dilutions. Reactions were mostly quick, leading to significant improvements, including complete recoveries.

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22:11

Sodium butyrate protects against noise-induced hearing loss in Guinea pigs. "IndyWatch Feed Health"

PMID:  Neurosci Lett. 2017 Nov 1 ;660:140-146. Epub 2017 Sep 18. PMID: 28928030 Abstract Title:  The histone deacetylase inhibitor sodium butyrate protects against noise-induced hearing loss in Guinea pigs. Abstract:  Noise-induced hearing loss (NIHL) severely impacts the quality of life of affected individuals. Oxidative stress resulting from noise exposure is a significant cause of NIHL. Although histone deacetylase (HDAC) inhibitors were shown to protect against NIHL, the underlying mechanism remains unclear, and it is not known how they act on noise-induced oxidative stress. In the current study, we investigated the expression levels of acetyl-histone H3 (Lys9) (H3-AcK9), histone deacetylase 1 (HDAC1), and 3-nitrotyrosine (3-NT), an oxidative stress marker, in a guinea pig model of NIHL using immunohistology and Western blotting. We then assessed the effects of systemic administration of the HDAC inhibitor, sodium butyrate (SB), on noise-induced permanent threshold shifts (PTS), hair cell (HC) loss, and changes in the above mentioned markers. The results showed that SB attenuated noise-induced PTS and outer hair cell loss. SB treatment promoted H3-AcK9 expression and repressed HDAC1 expression in the nuclei of HCs and Hensen's cells after noise exposure. Furthermore, SB attenuated the noise-induced increase of 3-NT expression in HCs and Hensen's cells. These findings suggest that SB protects against NIHL by reversing the noise-induced histone acetylation imbalance and inhibiting oxidative stress in cochlear HCs and Hensen's cells. SB treatment may represent a potential strategy to prevent and treat NIHL.

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21:59

Playboys Crystal Heffner Just Woke Up The World About The Truth Behind Breast Implants "IndyWatch Feed Health"

Crystal Heffner, celebrity model and wife of the late Hugh Heffner recently opened up to her fans and the public about her decision to remove her breast implants. She released a photo after her recovery from her explanting surgery along with details about her story:  Crystal Heffner Explains Why She Removed Her Breast Implants My Breast Implants... View Article

The post Playboys Crystal Heffner Just Woke Up The World About The Truth Behind Breast Implants appeared first on Healthy Holistic Living.

21:48

Butyrate or phenylbutyrate and could be novel types of prophylactic and therapeutic treatments for pterygium. "IndyWatch Feed Health"

PMID:  Int J Ophthalmol. 2017 ;10(9):1337-1343. Epub 2017 Sep 18. PMID: 28944189 Abstract Title:  Suppression of fibrosis in human pterygium fibroblasts by butyrate and phenylbutyrate. Abstract:  AIM: To evaluate the antifibrogenic effects of butyrate or phenylbutyrate, a chemical derivative of butyrate, in human pterygium fibroblasts.METHODS: Human pterygium fibroblasts obtained from patient pterygium tissue were treated with butyrate or phenylbutyrate for 48h. Expression of-smooth muscle actin, collagen I, collagen III and matrix metalloproteinase-1 mRNA was measured by quantitative real-time reverse transcription polymerase chain reaction, and acetylated histone was evaluated by Western blotting.RESULTS: Butyrate inhibited-smooth muscle actin, type III collagen and matrix metalloproteinase-1 expressions, and phenylbutyrate inhibited types I and III collagen and matrix metalloproteinase-1 expressions without changing cell viability as well as both of these increased histone acetylation. These results suggested thatbutyrate and phenylbutyrate suppress fibrosis through a mechanism involving histone deacetylase inhibitor.CONCLUSION: This indicates that butyrate or phenylbutyrate have antifibrogenic effects in human pterygium fibroblasts and could be novel types of prophylactic and/or therapeutic drugs for pterygium, especially phenylbutyrate, which does not have the unpleasant smell associated with butyrate.

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21:22

Dr. Brownstein: New Blood Pressure Guidelines Creates Millions of New Customers for Big Pharma "IndyWatch Feed Health"

Closeup of nurse checking senior woman blood pressure

New Hypertension Guidelines:  Same Old Song

by Dr. Brownsteins
Holistic Medicine

On Tuesday, November 14, 2017, the front page of the New York Times was headlined, New High Blood Pressure Norm to Affect Millions.  Similar headlines were plastered across the internet and in every major news outlet.

The NYT article explained, the nations leading heart experts issued new guidelines for high blood pressure that means tens of millions more Americans will meet the criteria for the condition and will need to change their lifestyles or take medicines to treat it.  The new guidelines were based on an ongoing analysis of the 2015 Sprint study.

The Big Pharma Cartel must be celebrating as they now have millions of more customers.

When I was in medical school, we were taught that blood pressure naturally goes up with age.

Guess what?  That is still true.

The elderly have stiffer arteries than they did when they were young and they generally require a higher blood pressure to pump their blood from the head to the toes.  I was taught to add 100 to a patients age and the resulting number is a normal systolic blood pressure.

Since medical school, there have been many changes to what I was taught.

First, the Powers-That-Be tightened the systolic (the higher number) blood pressure to read as anything less than 140 mmHg.  In 2013, surprisingly, the recommendations were relaxed to less than 150 mmHg for patients 60 years and older.  I wrote about this change here:  http://blog.drbrownstein.com/blood-pressure-and-lipid-guidelines-for-the-elderly-useless/. I wrote that I was pleased the blood pressure recommendations were relaxed.

Now, I am not so pleased.  In fact, I think my blood pressure is rising as I read the new recommendations!

...

21:13

FREE DocuSeries: Doctors, Scientists, Researchers, and Legal Experts Expose Facts About Vaccines "IndyWatch Feed Health"

vaccine docuseries1

Health Impact News

Health care entrepreneur and activist Dr. Patrick Gentempo, teamed up with Dr. Beau Pierce, CEO of Circle of Docs and award-winning documentary filmmaker Jeff Hays are offering to the public FREE viewing of their immensely popular Vaccines Revealed docuseries.

The series begins November 28, 2017 and will continue for 9 days, until December 7th. Register FREE online here.

With an award-winning film crew, they flew all over the world and got exclusive access to whistleblowers, former drug reps and university scientists.

This is powerful If you want the latest, real information you will not want to miss this.

The drug and vaccine industry is a multi-BILLION dollar enterprise focused more on profits than human lives.

It took months and months of care, attention and energy to edit each part of this stunning series. And now its finally ready for the world to see.

Vaccines Revealed features exclusive interviews with the worlds most acclaimed experts in research, medicine, holistic care and natural health.

Vaccine Documentary Speakers1 Vaccine Documentary Speakers2 Vaccine Documentary Speakers3

Register FREE online here.

Comment on this article at...

21:11

Curcumin inhibits hepatitis B virus gene replication via down-regulation of cccDNA-bound histone acetylation. "IndyWatch Feed Health"

PMID:  World J Gastroenterol. 2017 Sep 14 ;23(34):6252-6260. PMID: 28974891 Abstract Title:  Curcumin inhibits hepatitis B virus infection by down-regulating cccDNA-bound histone acetylation. Abstract:  AIM: To investigate the potential effect of curcumin on hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) and the underlying mechanism.METHODS: A HepG2.2.15 cell line stably transfected with HBV was treated with curcumin, and HBV surface antigen (HBsAg) and e antigen (HBeAg) expression levels were assessed by ELISA. Intracellular HBV DNA replication intermediates and cccDNA were detected by Southern blot and real-time PCR, respectively. The acetylation levels of histones H3 and H4 were measured by Western blot. H3/H4-bound cccDNA was detected by chromatin immunoprecipitation (ChIP) assays. The deacetylase inhibitors trichostatin A and sodium butyrate were used to study the mechanism of action for curcumin. Additionally, short interfering RNAs (siRNAs) targeting HBV were tested along with curcumin.RESULTS: Curcumin treatment led to time- and dose-dependent reductions in HBsAg and HBeAg expression and significant reductions in intracellular HBV DNA replication intermediates and HBV cccDNA. After treatment with 20mol/L curcumin for 2 d, HBsAg and cccDNA levels in HepG2.2.15 cells were reduced by up to 57.7% (P

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21:08

FREE DocuSeries: Doctors, Scientists, Researchers, and Legal Experts Expose Facts About Vaccines "IndyWatch Feed Health"

vaccine docuseries1

Health Impact News

Health care entrepreneur and activist Dr. Patrick Gentempo, teamed up with Dr. Beau Pierce, CEO of Circle of Docs and award-winning documentary filmmaker Jeff Hays are offering to the public FREE viewing of their immensely popular Vaccines Revealed docuseries.

The series begins November 28, 2017 and will continue for 9 days, until December 7th. Register FREE online here.

With an award-winning film crew, they flew all over the world and got exclusive access to whistleblowers, former drug reps and university scientists.

This is powerful If you want the latest, real information you will not want to miss this.

The drug and vaccine industry is a multi-BILLION dollar enterprise focused more on profits than human lives.

It took months and months of care, attention and energy to edit each part of this stunning series. And now its finally ready for the world to see.

Vaccines Revealed features exclusive interviews with the worlds most acclaimed experts in research, medicine, holistic care and natural health.

Vaccine Documentary Speakers1 Vaccine Documentary Speakers2 Vaccine Documentary Speakers3

Register FREE online here.

Comment on this article at...

21:04

Sodium butyrate exerts protective effect against Parkinson's disease in mice. "IndyWatch Feed Health"

PMID:  J Neurol Sci. 2017 Oct 15 ;381:176-181. Epub 2017 Aug 24. PMID: 28991675 Abstract Title:  Sodium butyrate exerts protective effect against Parkinson's disease in mice via stimulation of glucagon like peptide-1. Abstract:  Sodium butyrate (NaB) has exhibited protective activity in neurological disorders. Here, we investigated the neuroprotective effect and potential mechanisms of NaB in a mouse model of Parkinson's disease (PD). A mouse was intraperitoneally treated with MPTP (30mg/kg) for 7 consecutive days to induce PD model and NaB (200mg/kg) was intragastrically treated for 3weeks. The behavioral tests were then conducted. Dopaminergic degeneration was evaluated by western blot and immunohistochemistry of tyrosine hydroxylase (TH) in the SN. Brain damage was assessed by histologic (Nissl staining for cell death), apoptosis-associated protein and tight junction (TJ) proteins studies. Meanwhile, the levels of colonic glucagon-like peptide-1 (GLP-1) and cerebral GLP-1 receptor (GLP-1R) expression were assessed. Our results showed that NaB improved neurobehavioral impairment including cognitive behavior and coordination performance. Moreover, NaB treatment prevented the MPTP-induced dopaminergic degeneration and decreased expression level of TH in the striatum. NaB treatment attenuated the PD-associated disruption of BBB by upregulation of Occludin and zonula occludens (ZO)-1. In addition, NaB resulted in increased level of Bcl-2 and decreased level of Bax. Particularly, NaB-treated mice with PD exhibited increased colonic GLP-1 level as well as upregulation of brain GLP-1R expression compared with PD group. Our findings suggest that NaB has potential as a novel therapeutic for treatment of PD, and its mechanism was associated with stimulating colonic GLP-1secretion.

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20:48

Sodium butyrate promotes apoptosis in breast cancer cells. "IndyWatch Feed Health"

PMID:  Lipids Health Dis. 2017 Nov 2 ;16(1):208. Epub 2017 Nov 2. PMID: 29096636 Abstract Title:  Sodium butyrate promotes apoptosis in breast cancer cells through reactive oxygen species (ROS) formation and mitochondrial impairment. Abstract:  BACKGROUND: Sodium butyrate (NaBu) is a short-chain fatty acid which serves as a histon deacetylase inhibitor and has received considerable interest as a possible regulator of cancer cell death. The regulatory effect of NaBu on cancer cell growth or death has yet to be illustrated in many cancers including breast cancer. This study is aimed to elucidate the possible effect of NaBu on regulation of breast cancer growth and apoptosis.METHODS: The cytotoxic effect of NaBu on the growth of breast cancer cells (MCF-7 and MDA-MB-468) and normal breast cells (MCF-10A) was determined using MTT assay. Annexin-V-FITC staining and PI staining were performed to detect apoptosis and cell cycle distribution using Flow cytometry, the level of mitochondrial membrane potential (m), Reactive oxygen species (ROS)formation and caspase activity were determined accordingly.RESULTS: Based on our data, NaBu induced a dose and time-dependent cell toxicity in breast cancer cells which was related to the cell cycle arrest and induction of apoptosis. The impact of NaBu on MCF-10A cell toxicity, cell cycle distribution and apoptosis was inconsiderable. NaBu-elicited apoptosis was accompanied by the elevated level of ROS, increased caspase activity and reduced mitochondrial membrane potential (m) in MCF-7 and MDA-MB-468 cells and with no effect on the above mentioned factors in MCF-10A cells.CONCLUSIONS: Our study provided insight in to the role of NaBu on the regulation of breast cancer cell growth and lighten up the pro-apoptotic activity of NaBu.

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20:38

FREE DocuSeries: Doctors, Scientists, Researchers, and Legal Experts Expose Facts About Vaccines "IndyWatch Feed Health"

vaccine docuseries1

Health Impact News

Health care entrepreneur and activist Dr. Patrick Gentempo, teamed up with Dr. Beau Pierce, CEO of Circle of Docs and award-winning documentary filmmaker Jeff Hays are offering to the public FREE viewing of their immensely popular Vaccines Revealed docuseries.

The series begins November 28, 2017 and will continue for 9 days, until December 7th. Register FREE online here.

With an award-winning film crew, they flew all over the world and got exclusive access to whistleblowers, former drug reps and university scientists.

This is powerful If you want the latest, real information you will not want to miss this.

The drug and vaccine industry is a multi-BILLION dollar enterprise focused more on profits than human lives.

It took months and months of care, attention and energy to edit each part of this stunning series. And now its finally ready for the world to see.

Vaccines Revealed features exclusive interviews with the worlds most acclaimed experts in research, medicine, holistic care and natural health.

Vaccine Documentary Speakers1 Vaccine Documentary Speakers2 Vaccine Documentary Speakers3

Register FREE online here.

...

19:52

Butyrate acts on the gut-brain neural circuit to improve energy metabolism via reducing energy intake and enhancing fat oxidation by activating BAT. "IndyWatch Feed Health"

PMID:  Gut. 2017 Nov 3. Epub 2017 Nov 3. PMID: 29101261 Abstract Title:  Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit. Abstract:  OBJECTIVE: Butyrate exerts metabolic benefits in mice and humans, the underlying mechanisms being still unclear. We aimed to investigate the effect of butyrate on appetite and energy expenditure, and to what extent these two components contribute to the beneficial metabolic effects of butyrate.DESIGN: Acute effects of butyrate on appetite and its method of action were investigated in mice following an intragastric gavage or intravenous injection of butyrate. To study the contribution of satiety to the metabolic benefits of butyrate, mice were fed a high-fat diet with butyrate, and an additional pair-fed group was included. Mechanistic involvement of the gut-brain neural circuit was investigated in vagotomised mice.RESULTS: Acute oral, but not intravenous, butyrate administration decreased food intake, suppressed the activity of orexigenic neurons that express neuropeptide Y in the hypothalamus, and decreased neuronal activity within the nucleus tractus solitarius and dorsal vagal complex in the brainstem. Chronic butyrate supplementation prevented diet-induced obesity, hyperinsulinaemia, hypertriglyceridaemia and hepatic steatosis, largely attributed to a reduction in food intake. Butyrate also modestly promoted fat oxidation and activated brown adipose tissue (BAT), evident from increased utilisation of plasma triglyceride-derived fatty acids. This effect was not due to the reduced food intake, but explained by an increased sympathetic outflow to BAT. Subdiaphragmatic vagotomy abolished the effects of butyrate on food intake as well as the stimulation of metabolic activity in BAT.CONCLUSION: Butyrate acts on the gut-brain neural circuit to improve energy metabolism via reducing energy intake and enhancing fat oxidation by activating BAT.

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19:44

This reviews the effects of butyrate on modulating miRNA expression in colorectal cancer. "IndyWatch Feed Health"

PMID:  Genet Epigenet. 2017 ;9:1179237X17729900. Epub 2017 Sep 25. PMID: 28979170 Abstract Title:  Epigenetic Regulation of Gene Expression Induced by Butyrate in Colorectal Cancer: Involvement of MicroRNA. Abstract:  Colorectal cancer (CRC) is the third most common cause of cancer mortality globally. Development of CRC is closely associated with lifestyle, and diet may modulate risk. A Western-style diet is characterised by a high intake of red meat but low consumption of fruit, vegetables, and whole cereals. Such a diet is associated with CRC risks. It has been demonstrated that butyrate, produced by the fermentation of dietary plant fibre, can alter both genetic and epigenetic expressions. MicroRNAs (miRNAs) are small non-coding RNAs that are commonly present in both normal and tumour cells. Aberrant miRNA expression is associated with CRC initiation, progression, and metastasis. In addition, butyrate can modulate cell proliferation, differentiation, apoptosis, and miRNA expression in CRC. In this review, the effects of butyrate on modulating miRNA expression in CRC will be discussed. Furthermore, evidence on the effect of butyrate on CRC risk through reducing oncogenic miRNA expression will be presented.

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16:05

Honeywell announces plans to idle Metropolis plant, reduce workforce by 170 positions "IndyWatch Feed Health"

METROPOLIS  On March 11, 2011, a nearly six-minute, 9.0 magnitude earthquake violently shook Japan, unleashed a deadly tsunami and set off three nuclear reactor meltdowns resulting in high radioactive releases that forced thousands to flee their homes.

Following the disaster, numerous countries shut down reactors and implemented nuclear power phase-out policies.

Six years later, the long-term effects of the Fukushima disaster are delivering a hard economic punch to deep Southern Illinois. Honeywell announced on Monday it intends to idle its Metropolis plant that produces uranium hexafluoride, or UF6  an essential compound used to produce enriched uranium for use as fuel in nuclear power plants  in the first quarter of 2018.

Its the only plant in the country that converts uranium ore into UF6, and its one of only a handful of private industrial employers in Massac County and the surrounding Ohio River Valley region that provides workers with steady middle-class wages.

In announcing plans to indefinitely close its plant and reduce its workforce by 170 full-time and 105 contract workers, Honeywell cited significant challenges facing the nuclear industry, which the company says is oversupplied with uranium hexafluoride, or UF6.

In particular, the decrease in demand in Japan and Germany following the Fukushima disaster has had a significant impact on the industry and continues to create an over-supplied market for the uranium fuel cycle, and a downward trend in the uranium markets, a Honeywell spokesperson wrote in a emailed statement.

Citing an analysis from Energy Resource International, Honeywell stated that since the Fukushima disaster, global demand for nuclear fuel has dropped 15 percent, and demand is not anticipated to rise before 2020.

As a result of this business outlook, Honeywell plans to temporarily idle production of UF6 at its Metropolis site, while maintaining minimal operations to support a future restart should business conditions improve, the company wrote.

A spokesperson said the company will keep 26 Honeywell employees and 18 contractors at the facility to support minimal on-site opera...

15:38

Acid fumes hospitalize UC Riverside student "IndyWatch Feed Health"

A UC Riverside graduate student was hospitalized after he was exposed to hydrofluoric acid fumes in a science building, the Riverside County Department of Environmental Health said.

The incident happened about 11 p.m. Thursday, Nov. 16, according to a discharge report that the county is required to release under the California Health and Safety Code.

A graduate student was using hydrofluoric acid to clean silicon wafers in the Materials Science and Engineering building and didnt have proper ventilation, the report said. He inhaled fumes and had difficulty breathing, so he went outside and then took himself to a hospital, the report said. He was examined and decontaminated, and the area where hed been working was deemed safe to reoccupy.

Hydrofluoric acid has industrial purposes such as metal cleaning. Poisoning can occur if absorbed through the skin or eyes.

*Original article online at http://www.pe.com/2017/11/20/acid-fumes-hospitalize-uc-riverside-student/

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