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Wednesday, 19 September

17:10

Honeys Health Benefits and Why You Need It In Your Medicinal Pantry "IndyWatch Feed Health"

Honeys Health Benefits and Why You Need It In Your Medicinal Pantry

By Jeremiah Johnson

Ready Nutrition readers, the use of honey in medical emergencies is older than recorded history. There are many reasons that honey is excellent for use in first aid and homeopathic aids such as cuts, abrasions, burns, coughs, colds, and infections. Honey has anti-inflammatory properties and is also anti-bacterial/microbial in nature. Honey is bacteriostatic against certain bugs such as E. coli and Salmonella. Bacteriostatic means that honey prevents these organisms from growingand as these two are found in food, thats a good thing.

Honey actually fights against bacteria such as Pseudomonas aeruginosa, and Staphylococcus aureus. The latter is the most common bacteria found in the human nasal passages and nose. Also, honey should be as raw as possible, and the darker the better.  Dark honey contains more antioxidants, and it is more effective in fighting microorganisms and bacteria.

It is highly effective as a cough-suppressant and as a demulcent. That latter term means something that coats the throat and the linings of the trachea and mouth to soothe the surfacesa principle for which cough drops and lozenges have a primary function/goal.  Buckwheat honey surpasses dextromethorphan (the primary cough suppressant found in Robitussin, for example) in terms of cough suppressant action.

...

17:00

One of Americas Largest Egg Producers Caught Using Child Slaves Given to Them by US Govt "IndyWatch Feed Health"

By John Vibes

Marion, Ohio This Monday, another suspect pleaded guilty to his role in a human-trafficking ring that took advantage of immigrant children and forced them into slave labor. 50-year-old Pablo Duran Ramirez Jr. is the fourth person to plead guilty in the case, which involved a number of children being forced to work on an egg farm. He faces up to a decade in prison at his sentencing in January.

According to court records, a labor company named Haba Corporate Services, owned by Ramirez, arranged for trafficked immigrants to work with Trillium Farms, where they were physically threatened and forced to live in horrible conditions.

Trillium reportedly paid Haba $6 million for the immigrant workers, who were promised that they would be provided with jobs and education when they got to the States. Some of the workers were as young as 14 years old.

According to prosecutors, Ramirez was aware that these workers were children and he also knew about the conditions and abuse that these children were exposed to. When the farm was eventually raided, federal agents found nearly 40 workers on the site.

As The Free Thoug...

16:54

Video: Interview with Stanford PhD on vaccines "IndyWatch Feed Health"

In the video below, Steven Keller- The Emotion Reset Coach- interviews his friend who has not just an undergraduate degree in biology from Stanford, but two Masters degrees and a Ph.D. Watch and see that even PhDs doubt what theyve been taught. Its what you do with your doubt that counts. RELATED STORY: RFK, Jr. proves HHS []

The post Video: Interview with Stanford PhD on vaccines appeared first on Health Nut News.

16:30

Trump Anxiety Disorder Is More Fake News "IndyWatch Feed Health"

Its a strange thing when going down a rabbit hole of a thought actually leads to something more interesting. When writing for my blog I try and avoid bashing easy targets too often, if nothing else because I get bored and frustrated. Despite what those who know me personally may think, theres only so many times an hour I can wish hellish eternal torment on the perpetrators of Personal Independence Payment (PIP) atrocities, or Piers Morgan, or those who insist that depression and suicidality are choices consciously made by an individual. So when a couple of friends drew my attention to a recent article claiming that Trump Anxiety Disorder is a thing, it pushed several of my mental health buttons but I resolved not to post about the ridiculousness of this. Besides, I could only find references to it on Fox News affiliated content and Mail Online  sources hardly known for journalistic integrity of late. But with the rush to label almost any type of mental distress as disorder in todays culture, I feel these arguments cannot be ignored completely  the biomedical model of mental illness is so prevalent that TAD seems like a bandwagon that people will jump on, even if it is completely laughable.

Annoyingly, some news stories and ideas refuse to shut up, and its rattled around my brain for the past few days. So here I am writing about it, but I want to take a broader view of it. I often complain in my corner of the internet about the overarching dogma of the social model within disability circles. Now for those that dont know the social model of disability was devised towards the end of the 20th century, and is summed up rather neatly by the disability charity Scope, who say that:

people are disabled by barriers in society, not by their impairment or difference. Barriers can be physical, like buildings not having accessible toilets. Or they can be caused by peoples attitudes to difference, like assuming disabled people cant do certain things.

The social model helps us recognise barriers that make life harder for disabled people. Removing these barriers creates equality and offers disabled people more independence, choice and control.

There is, of course, a huge amount of positivity and empowerment in this view of disability, and I do not wish to remove it altogether. The social model has done a huge amount for disability perception, activism and identity as well as giving the public a very simple way of understanding the limita...

15:55

Chronic Exposure to Sodium Fluoride Triggers Oxidative Biochemistry Misbalance in Mice: Effects on Peripheral Blood Circulation. "IndyWatch Feed Health"

Excerpts:

The fluoride exposure doses used in our study (10 and 50?mg/L) are often employed [3234] and lead to a plasma fluoride levels in rodents similar to the ones found in humans consuming artificially fluoridated water or living in areas of endemic fluorosis, respectively [35]. It is important to note that F metabolism in rodents is 510 times faster than that in humans and the concentrations used in this investigation, 10 and 50?mg/L, correspond to 1-2 and 510?mg/L, respectively, for humans in the drinking water [Dunipace et al., 1995].

Fluoride, mainly in the form of hydrogen fluoride (HF), is transported through the cell membrane by nonionic diffusion [36]. The main mechanism of fluoride toxicity in cells is associated with its ability to interact with enzymes; most often, the fluoride can lead to inhibition of enzymatic activity (e.g., phosphatases, GTPases, and ATPases). In addition, fluoride can also inhibit the protein secretion and/or synthesis involved in signaling pathways (mitogen-activated protein kinase (MAPK), p53, activator protein-1 (AP-1), and nuclear factor kappa B (NF-?B) [3739] and antioxidant enzymes (SOD, glutathione levels, and CAT) [40]. Thus, the inhibition of antioxidant enzymes results in the excessive production of ROS at the mitochondrial level, leading to cell damage. On the other hand, the fluoride at lower concentrations may stimulate enzymatic activity and promotes the increase of the cell proliferation and apoptosis because of the increase in proapoptotic proteins, such as caspase-3 and caspase-9 [41, 42]. Therefore, fluoride can also induce oxidative stress leading to the production of ROS, which triggers the release of cytochrome c from mitochondria into the cytosol and further activates caspase-3 leading to apoptotic cell death [41, 42].

15:25

Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes. "IndyWatch Feed Health"

Excerpts:

Apoptosis, characterized by nuclear fragmentation, chromatic condensation, and caspase activation, is a major molecular mechanism to eliminate cells (Oropesa-.vila et al. 2017 ). Apoptosis is observed widely in liver diseases (Cui et al. 2018 ; Potz et al. 2016 ). Fluoride, as an exogenous toxicant, has been reported to cause apoptosis in the liver (Khan et al. 2018 ). Song et al. (2015 ) reported that chronic fluoride exposure induced the liver apoptosis through activating the apoptotic pathways. Zhan et al. (2006 ) treated the pig with 400 mg/kg fluoride for 50 days, and found that fluoride induced apoptosis by elevating the oxidative stress and further activating caspase-9 and caspase-3. Bcl-2, Cyt-c, Apaf-1, caspase3, caspase12, and p53 are key genes in the apoptosis. Among them, Bcl-2 is an anti-apoptotic protein and the others are proapoptotic protein (Ryu et al. 2018 ; Zhu et al. 2017 ). In this study, we evaluated the mRNA and protein expression of these genes to determine the effects of fluoride on the apoptosis. The mRNA expressions of caspase3, caspase12, and p53 were significantly increased; the mRNA levels of Cyt-c and Apaf-1 were significantly in the 50 and 100 mg/L NaF. However, the mRNA expression of Bcl-2 was significantly decreased in the NaF treated group. The results of protein levels of caspase3 and Cyt-c were similar with the mRNA. The above results indicated that fluoride exposure induced apoptosis by activating the apoptotic pathway in the liver.

Autophagy, as an important modulator for cellular homeostasis, is known to eliminate the intracellular cell contents (Sungwoo et al. 2016 ). Recent studies have demonstrated that autophagy is closely related to liver injury (Lv and Qiao 2018 ). LC3 is a marker indicating the formation of autophagic vesicles, which plays the role through LC3I converting to LC3II. The increase in the ratio of LC3BII/ LC3BI reflects the levels of autophagic activity (Sungwoo et al. 2016 ). Benlin1 promotes the formation of autophagosomes by combining with PI3K (Cheng et al. 2017 ). As an autophagic substrate, the enhancement of autophagosome formation or the blockage of autophagosome degradation leads to the accumulation of p62, eventually p62 enter into mature autophagosomes, and degrade in autophagosomes, so the levels of p62 are negatively correlated with autophagy (Zhao et al. 2018 ). Because of the important role of these factors in autophagy, many studies have used them as indicators of autophagy (Zhang et al. 2018a ). In the present study, TEM results showed that autophagosomes were significantly increased in the cells after 50 and 100 mg/L NaF treated. Moreover, it was observed that fluoride induced an increase in the mRNA and protein expressions of LC3 and Beclin1, while led to a decrease in p62 mRNA and protein levels. MDC is an acidic dye, which stains autophagosomes and lysos...

14:46

Pharma Begins Vaccine Experiments On Kids In St. Louis "IndyWatch Feed Health"

Vaccine experiments have begun in St. Louis on kids between the ages of 9 and 17. The nasal flu vaccine experiments will take place at the Vaccine and Treatment Evaluation Unit site. The experiments are funded by...

The post Pharma Begins Vaccine Experiments On Kids In St. Louis appeared first on Vaxxter.

14:24

Texas doctor claims female physicians do not work as hard as male docs do "IndyWatch Feed Health"

It seems some men still havent gotten the memo that women will no longer be treated like second-class citizens. Last month, in an issue devoted to women in medicine, the Dallas Medical Journal asked area doctors what they thought of the fact that female physicians salaries are reportedly one-third less than male physicians  and one male doc gave a candid []

The post Texas doctor claims female physicians do not work as hard as male docs do appeared first on Health Nut News.

14:24

Important to stop drinking this, levels of liver disease are soaring "IndyWatch Feed Health"

According to the American Cancer Society, liver cancer affects an estimated 41,000 Americans each year, and prevalence is rising. Between 2000 and 2016, the annual death toll from liver cancer rose by 43 percent for men and 40 percent for women, killing more than 11,000 people in 2016. The five-year survival rate for localized liver cancer is 31 percent, []

The post Important to stop drinking this, levels of liver disease are soaring appeared first on Health Nut News.

14:00

The End of the Autism EpidemicFinally? "IndyWatch Feed Health"

September 19, 2018 Parental engagement with mainstream medicine is on the brink of a major collapse, and a new book by J.B. Handley, co-founder of Generation Rescue, activist, and autism dad, may just be the tipping point that pushes a Continue reading

The post The End of the Autism EpidemicFinally? appeared first on The Thinking Moms' Revolution.

14:00

Four years after readers raise concerns, journal finally retracts climate paper "IndyWatch Feed Health"

The wheels of scientific publishing turn slowly but they do (sometimes) turn. In January, we reported on the case of a paper on global warming marred by several problems, including allegations of plagiarism and false claims by the authors which readers had raised as early as 2014, with no result. (Find a discussion Continue reading Four years after readers raise concerns, journal finally retracts climate paper

12:06

Debut Day!! JB Handley's How To End the Autism Epidemic "IndyWatch Feed Health"

It's DEBUT DAY for JB Handley's new book, How to End the Autism Epidemic. Check out the Amazon stats from last evening. Order your copy today! Don't forget to use Amazon Smile to support Age of Autism. Paperback: 304 pages...

12:01

Antidepressants May Cause Antibiotic Resistance "IndyWatch Feed Health"

From Medical Xpress: A key ingredient in common antidepressants such as Prozac could be causing antibiotic resistance, according to new University of Queensland research.

A study led by Dr Jianhua Guo from UQs Advanced Water Management Centre focused on fluoxetine, a prescription drug used to help people recover from depression, obsessive-compulsive disorder or eating disorders.

Dr Guo said while overuse and misuse of  is generally considered the major factor contributing to the creation of superbugs, researchers were often unaware that non-antibiotic pharmaceuticals could also cause .

It has previously been an invisible factor in the spread of antibiotic resistance, but we should consider this a warning.

Further work is required to investigate effects of  on antibiotic resistome in .

Antimicrobial  has become a major threat to public health globally with approximately 700,000 people a year dying from antimicrobial-resistant infections.

This is predicted to reach 10 million people by 2050 unless global action is taken now.

Article

07:00

Phthalate Exposure Threatens Human Survival "IndyWatch Feed Health"

By Dr. Mercola

Infertility has become increasingly pervasive in recent decades. In Sperm Count Zero,1 GQ Magazine discusses this troubling fact, noting the situation has become so dire that within a generation we may lose the ability to reproduce entirely.

The article highlights research2,3 published last year, which found total sperm counts in North America, Europe, Australia and New Zealand dropped by nearly 60 percent between 1973 and 2013. (South American, Asian and African men had no noticeable decline, although this discrepancy could be due to the smaller sample sizes obtained from those countries.)

The paper in question was a meta-analysis of 185 studies and the largest of its kind. In a nutshell, men in many areas of the world are producing less semen overall, and the semen they do produce contains fewer sperm. Whats worse, the researchers found no evidence to suggest this downward trend is leveling off. As noted by GQ:

Sperm counts went from 99 million sperm per milliliter of semen in 1973 to 47 million per milliliter in 2011, and the decline has been accelerating. Would 40 more years or fewer bring us all the way to zero?

Aside from the implications this has on the human species as a whole, reduction in sperm production is also a warning sign that mens health is in serious jeopardy, as poor semen quality has been linked to a number of other health issues, including a higher risk for diabetes, heart disease, cancer and early death. Researchers also warn that men are becoming increasingly less male overall.

Testosterone Levels Are Dropping Too

Along with sperm, mens testosterone levels have dropped in recent decades as well, and exposure to endocrine-disrupting chemicals in utero and beyond appears to be a driving factor.4 GQ reports:...

Common Painkiller Is Causing Many Heart Attacks "IndyWatch Feed Health"

By Dr. Mercola

Nearly 25 million American adults suffer from pain on a daily basis and 23 million report experiencing severe pain.1 In fact, pain affects more Americans than diabetes, heart disease and cancer combined and is cited as the most common reason Americans access health care.

Pain is a major contributor to health care costs and a leading cause of disability.2 The World Health Organization (WHO) estimates at least half adult population in the world experienced at least one headache in the past year.3

In an effort to alleviate pain, many turn to using nonsteroidal anti-inflammatory medications (NSAIDs) often prescribed after an injury, to treat menstrual cramps and to reduce fever or headache. In the U.S., nearly 70 million prescriptions are written and 30 billion doses are consumed when over-the-counter (OTC) NSAIDs are included.4

Although they may appear innocuous as they are sold in local convenience stores, by conservative estimates, over 105,000 people are hospitalized every year from side effects of these drugs and over 16,000 died.5 Long-term side effects from NSAIDs are varied, but research demonstrates short-term use significantly increases your risk of heart attack.6

OTC Painkiller Increases Your Risk of Heart Attack

A recent study published in BMJ examined cardiovascular risk in individuals taking the NSAID diclofenac (marketed in the U.S. under the names Voltarol or Voltaren) compared against other traditional NAIDs.7 Danish researchers used 252 cohort studies mimicking the design strategy, which included more than 6.3 million adults who had at least one year of continuous prescription records.

They analyzed the data to evaluate the risk of major adverse cardiovascular events occurring within 30 days of first taking diclofenac, naproxen,...

Catheters Are Spreading Superbugs "IndyWatch Feed Health"

By Dr. Mercola

Today, many are so used to the idea an antibiotic can cure almost any infection, few consider the possibility this remedy may soon no longer be an option. Antibiotics have increased human life span by nearly a decade and certain conditions could simply not be treated without them.1

In many ways, modern medicine is built on a foundation of antibiotics. It is now severely threatened, however, by the emergence and phenomenal growth of antibiotic-resistant bacteria. Prior to the development of antibiotics, half of the world's population died from infections.

The reality is antibiotic-resistant microbes have now become a major threat to public health worldwide. According to the British Office of National Statistics, for the first time life expectancy in the U.K. has dropped as the result of antibiotic resistance.2 This is a man-made epidemic triggered by the widespread misuse of antibiotics.3

In the U.S., resistant pathogens are conservatively estimated to cause at least 2 million infections annually and lead to 23,000 deaths each year. An estimated 25 to 60 percent of Klebsiella pneumoniae (K. pneumoniae) blood infections are now resistant to several strains of antibiotics.

The rise in resistance to multiple drugs has increased the use of carbapenems, a class of last-line antibiotics. Research from Australia now demonstrates multidrug-resistant Staphylococcus epidermidis (S. epidermidis), found on the skin of all humans, may be responsible for an alarming number of antibiotic-resistant sepsis infections.4

Mutated Common Bacteria Found

Sepsis is a massive immunological response to a bacterial infection in the blood. It often leads to organ failure or injury and is a medical emergency responsible for killing over 250,000 Americans each year.5 During the infection, the body releases chemicals to fight bacteria, which also trigger widespread inflammation.6

In severe cases, one or m...

06:09

Hair growth-promoting activity of hot water extract of Thuja orientalis. "IndyWatch Feed Health"

PMID:  BMC Complement Altern Med. 2013 Jan 10 ;13:9. Epub 2013 Jan 10. PMID: 23305186 Abstract Title:  Hair growth-promoting activity of hot water extract of Thuja orientalis. Abstract:  BACKGROUND: Thuja orientalis has been traditionally used to treat patients who suffer from baldness and hair loss in East Asia. The present study sought to investigate the hair growth-promoting activity of T. orientalis hot water extract and the underlying mechanism of action.METHODS: After T. orientalis extract was topically applied to the shaved dorsal skin of telogenic C57BL/6 N mice, the histomorphometric analysis was employed to study induction of the hair follicle cycle. To determine the effect of T. orientalis extract on the telogen to anagen transition, the protein expression levels of-catenin and Sonic hedgehog (Shh) in hair follicles were determined by immunohistochemistry.RESULTS: We observed that T. orientalis extract promoted hair growth by inducing the anagen phase in telogenic C57BL/6 N mice. Specifically, the histomorphometric analysis data indicates that topical application of T. orientalis extract induced an earlier anagen phase and prolonged the mature anagen phase, in contrast to either the control or 1% minoxidil-treated group. We also observed increases in both the number and size of hair follicles of the T. orientalis extract-treated group. Moreover, the immunohistochemical analysis reveals earlier induction of-catenin and Shh proteins in hair follicles of the T. orientalis extract-treated group, compared to the control or 1% minoxidil-treated group.CONCLUSION: These results suggest that T. orientalis extract promotes hair growth by inducing the anagen phase in resting hair follicles and might therefore be a potential hair growth-promoting agent.

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05:41

Pro-oxidant-antioxidant balance and antioxidant properties of Thuja orientalis. "IndyWatch Feed Health"

PMID:  Curr Mol Pharmacol. 2018 ;11(2):109-112. PMID: 28382868 Abstract Title:  Prooxidant-Antioxidant Balance and Antioxidant Properties of Thuja orientalis L: A Potential Therapeutic Approach for Diabetes Mellitus. Abstract:  BACKGROUND: Diabetes mellitus (DM) is a major health problem with an increasing global prevalence. It is usually associated with an imbalance between pro-oxidant mechanisms and antioxidant defenses, contributing to oxidative-stress, and this leads to an increased susceptibility to endothelial dysfunction, atherosclerosis, insulin-resistance and impaired-pancreatic-cell function.OBJECTIVE: We have assessed the Prooxidant-antioxidant balance (PAB) and anti-hemolytic effect of Thuja orientalis L using the PAB assay and the analysis of hematological markers.METHODS: The antioxidant and anti-hemolytic activity of Thuja orientalis was evaluated using the PAB assay and the inhibition of RBC hemolysis using the hydrogen peroxide hemolysis test. The percentage of anti-hemolysis was calculated from the ratio of the measurements (A-B)/B100.RESULTS: Our results showed that the antioxidant effect of Thuja orientalis L. was greater in water than in ethyl-acetate, ethanol and methanol extract, respectively. We also observed its anti-hemolytic effect, which was higher in water, than in ethyl-acetate, methanol and ethanol extract, respectively. In particular our data showed that the H2O2-induced RBC hemolysis was inhibited in a dose-dependent manner.CONCLUSION: we demonstrated the antioxidant and anti-hemolytic effect of Thuja orientalis L. extracts in human serum and RBC, showing its potential property of reducing free radicals supporting further investigations to assess its functional role in larger samples size and in vivo models, as a potential antioxidant agent.

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05:20

An extract of Thuja orientalis L. inhibited angiogenesis in zebra fish and suppressed the growth of human lung cancer cells. "IndyWatch Feed Health"

PMID:  Biomed Pharmacother. 2018 Oct ;106:699-706. Epub 2018 Jul 11. PMID: 29990861 Abstract Title:  Non-toxic and non teratogenic extract of Thuja orientalis L. inhibited angiogenesis in zebra fish and suppressed the growth of human lung cancer cell line. Abstract:  Lung cancer is a malignant tumour with minimal survival rate and the current treatments are not showing complete remission of tumour and have many side effects. Thus a natural herbal medicine with good anti-cancer properties is highly demanded. Thuja orientalis L. is a traditionally used medicine to cure cough, bronchitis, excessive menstruation, asthma, skin infection and premature baldness. In addition, recent studies have revealed that it has anti-proliferative and anti-cancer activity. Angiogenesis is the main reason for the propagation and metastasis of cancers. We therefore intended to study the effects of the leaf extract of Thuja orientalis L. on angiogenesis as well as lung cancer cell growth. We have tested the anti-angiogenesis efficiency by alkaline phosphatase assay and also analysed the in vivo toxicity and teratogenic effects of various concentration of Thuja orientalis L. extract by establishing an in vivo zebra fish (Danio rerio), a promising model for cancer research which share genetic structure similarity to that of human beings. Also we demonstrated an anti-cancer effect of leaf extract from Thuja orientalis L. on human lung cancer cell line (A549) by MTT and trypan blue assay. The results revealed that the Thuja orientalis L. extract is efficient in repressing lung tumour cell growth significantly (p0.01) in all treatments (2.4mg/ml to 0.3mg/ml) except 0.15mg/ml compared to the control. The in vivo toxicity assay has proven that it is non-toxic at concentrations 0.6mg/ml, 0.3mg/ml and 0.15mg/ml in zebrafish. The teratogenic assays revealed the therapeutic index (TI) as 0.808 with 0.7029mg/ml as LCconcentration at 24h which is within the desirable value (below 1) for drug administration. Noticeable inhibition of angiogenesis also was observed in treatment with 2.4mg/ml to 0.3mg/ml. Overall we found that Thuja orientalis L. plant leaf extract exhibits better anti-cancer properties as we have validated by in vitro and in vivo analysis.

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05:06

Cannabis analgesia in chronic neuropathic pain is associated with altered brain connectivity. "IndyWatch Feed Health"

PMID:  Neurology. 2018 Sep 5. Epub 2018 Sep 5. PMID: 30185448 Abstract Title:  Cannabis analgesia in chronic neuropathic pain is associated with altered brain connectivity. Abstract:  OBJECTIVE: To characterize the functional brain changes involved in-9-tetrahydrocannabinol (THC) modulation of chronic neuropathic pain.METHODS: Fifteen patients with chronic radicular neuropathic pain participated in a randomized, double-blind, placebo-controlled trial employing a counterbalanced, within-subjects design. Pain assessments and functional resting state brain scans were performed at baseline and after sublingual THC administration. We examined functional connectivity of the anterior cingulate cortex (ACC) and pain-related network dynamics using graph theory measures.RESULTS: THC significantly reduced patients' pain compared to placebo. THC-induced analgesia was correlated with a reduction in functional connectivity between the anterior cingulate cortex (ACC) and the sensorimotor cortex. Moreover, the degree of reduction was predictive of the response to THC. Graph theory analyses of local measures demonstrated reduction in network connectivity in areas involved in pain processing, and specifically in the dorsolateral prefrontal cortex (DLPFC), which were correlated with individual pain reduction.CONCLUSION: These results suggest that the ACC and DLPFC, 2 major cognitive-emotional modulation areas, and their connections to somatosensory areas, are functionally involved in the analgesic effect of THC in chronic pain. This effect may therefore be mediated through induction of functional disconnection between regulatory high-order affective regions and the sensorimotor cortex. Moreover, baseline functional connectivity between these brain areas may serve as a predictor for the extent of pain relief induced by THC.

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04:51

The leaf extracts of C. sativa, T. orientalis and P. guajava had potential for the control of both hospital and community-acquired MRSA. "IndyWatch Feed Health"

PMID:  J Integr Med. 2018 09 ;16(5):350-357. Epub 2018 Jul 29. PMID: 30120078 Abstract Title:  Antimicrobial activity of Cannabis sativa, Thuja orientalis and Psidium guajava leaf extracts against methicillin-resistant Staphylococcus aureus. Abstract:  OBJECTIVE: This study examined the antimicrobial activity of Cannabis sativa, Thuja orientalis and Psidium guajava against methicillin-resistant Staphylococcus aureus (MRSA) and used a standardized purification protocol to determine the presence and abundance of bioactive compounds in the leaf extracts.METHODS: In vitro antimicrobial activities of the ethanolic extracts of C. sativa, T. orientalis and P. guajava were tested against MRSA. The presence of bioactive molecules in these three leaves was evaluated using biochemical assays and high-performance thin-layer chromatography (HPTLC).RESULTS: Resistance to methicillin, penicillin, oxacillin and cefoxitin was observed in each of the clinical and nonclinical MRSA isolates. However, they were still vulnerable to vancomycin. Used individually, the 50% extract of each plant leaf inhibited MRSA growth. A profound synergism was observed when C. sativa was used in combination with T. orientalis (1:1) and when P. guajava was used in combination with T. orientalis (1:1). This was shown by larger zones of inhibition. This synergism was probably due to the combined inhibitory effect of phenolics present in the leaf extracts (i.e., quercetin and gallic acid) and catechin, as detected by HPTLC.CONCLUSION: The leaf extracts of C. sativa, T. orientalis and P. guajava had potential for the control of both hospital- and community-acquired MRSA. Moreover, the inhibitory effect was enhanced when extracts were used in combination.

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04:35

The present work provides a baseline in the study of the anti-virulence properties of the C. sativa essential oil against L. monocytogenes. "IndyWatch Feed Health"

PMID:  Front Cell Infect Microbiol. 2018 ;8:293. Epub 2018 Aug 22. PMID: 30186775 Abstract Title:  Attenuation ofVirulence byL. Essential Oil. Abstract:  Anti-virulence strategies are being explored as a novel approach to combat pathogens. Such strategies include inhibition of surface adhesion, tissue invasion, toxin production, and/or interference with the gene regulation of other virulence traits., the causative agent of listeriosis, is a facultative intracellular food pathogen characterized by a wide distribution in the environment. Its ability to persist within biofilms and to develop resistance to sanitizers is the cause of significant problems in food processing plants and of steep costs for the food industry. In humans, the treatment of listeriosis is hampered by the intracellular location of listeriae and the poor intracellular penetration of some antibiotics. Elevenisolates from patients who were diagnosed with invasive listeriosis in Italy in 2014-2016 were studied. Thisandstudy explored the antibacterial and anti-virulence properties of a steam-distilled essential oil ofL., which is being intensively investigated for its high content in powerful bioactive phytochemicals. Susceptibility experiments demonstrated a moderate bactericidal activity of the essential oil (Minimum Bactericidal Concentration>2048g/mL). Assessment of the effects of sublethal concentrations of the essential oil onvirulence traits demonstrated a significant action on motility. Listeriae were non-motile after exposure to the essential oil. Light and scanning electron microscopy documented aggregates of listeriae with the flagella trapped inside the cluster. Real-time RT-PCR experiments showed downregulation of flagellar motility genes and of the regulatory gene. The ability to form biofilm and to invade Caco-2 cells was also significantly reduced.larvae infected withgrown in presence of sublethal concentrations of the essential oil showed much higher survival rates compared with controls, suggesting that the extract inhibited tissue invasion. Food contamination withis a major concern for the food industry, particularly for plants making ready-to-eat and processed food. The present work provides a baseline in the study of the anti-virulence properties of theessential oil against. Further studies are needed to understand if it could be used as an alternative agent for the control ofin food processing plants.

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02:01

Try These 15 Stretches to Relieve a Stiff Neck, Tight Shoulders And Upper Back Pain! "IndyWatch Feed Health"

Stiffness and body pain is extraordinarily common, especially in todays day and age of desk jobs, long commutes, and time spent sitting watching your favorite television shows. Little things like sleeping in the wrong position can cause enough pain in your shoulders and back to affect your daily life (1). Rather than taking some painkillers,... View Article

The post Try These 15 Stretches to Relieve a Stiff Neck, Tight Shoulders And Upper Back Pain! appeared first on Healthy Holistic Living.

00:32

Blue light induces mitochondrial DNA damage and free radical production in epithelial cells. "IndyWatch Feed Health"

PMID:  J Biol Chem. 2005 Jun 3 ;280(22):21061-6. Epub 2005 Mar 29. PMID: 15797866 Abstract Title:  Blue light induces mitochondrial DNA damage and free radical production in epithelial cells. Abstract:  Exposure of biological chromophores to ultraviolet radiation can lead to photochemical damage. However, the role of visible light, particularly in the blue region of the spectrum, has been largely ignored. To test the hypothesis that blue light is toxic to non-pigmented epithelial cells, confluent cultures of human primary retinal epithelial cells were exposed to visible light (390-550 nm at 2.8 milliwatts/cm2) for up to 6 h. A small loss of mitochondrial respiratory activity was observed at 6 h compared with dark-maintained cells, and this loss became greater with increasing time. To investigate the mechanism of cell loss, the damage to mitochondrial and nuclear genes was assessed using the quantitative PCR. Light exposure significantly damaged mitochondrial DNA at 3 h (0.7 lesion/10 kb DNA) compared with dark-maintained controls. However, by 6 h of light exposure, the number of lesions was decreased in the surviving cells, indicating DNA repair. Isolated mitochondria exposed to light generated singlet oxygen, superoxide anion, and the hydroxyl radical. Antioxidants confirmed the superoxide anion to be the primary species responsible for the mitochondrial DNA lesions. The effect of lipofuscin, a photoinducible intracellular generator of reactive oxygen intermediates, was investigated for comparison. Exposure of lipofuscin-containing cells to visible light caused an increase in both mitochondrial and nuclear DNA lesions compared with non-pigmented cells. We conclude that visible light can cause cell dysfunction through the action of reactive oxygen species on DNA and that this may contribute to cellular aging, age-related pathologies, and tumorigenesis.

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00:32

Are Vaccine Manufacturers Concealing Deaths Caused by Vaccines by Manipulating Post-marketing Data? "IndyWatch Feed Health"

09-17-Infanrix-hexa-Vaccine_Featured_Image

Infant Deaths Following Vaccination: The Numbers Dont LieOr Do They?

by the Childrens Health Defense Team

National and international health agencies such as the Centers for Disease Control and Prevention (CDC), the European Medicines Agency (EMA) and the World Health Organization (WHO) routinely and emphatically claim that serious adverse events following vaccination are rare.

Nowhere is officialdoms minimization of vaccine risks more apparent than in these agencies position on vaccine-related deaths. The WHO, for example, states that so few deaths can plausibly be attributed to vaccines that it is hard to assess the risk statistically.

Nevertheless, once regulators have deemed that a given vaccine is safe enough to be licensed and widely marketed, vaccine manufacturers are supposed to do just thatthat is, continue to statistically assess a vaccines risks, including the risk of deathand regulators are supposed to carefully review the postlicensure data that pharmaceutical companies submit.

A 2017 commentary by India-based physicians Jacob Puliyel and C. Sathyamala in the Indian Journal of Medical Ethics describes a shocking dereliction of duty on the part of regulators who were presented with vaccine data carefully tailored to obscure serious risks.

Tackling concerns about infant deaths that have occurred following hexavalent vaccination in several European countries, the authors of the commentary show that GlaxoSmithKline (GSK) neglected to report to regulatory authorities that there was a statistically significant increased risk of sudden infant death in the four days after administration of its hexavalent vaccine...

00:23

Are Vaccine Manufacturers Concealing Deaths Caused by Vaccines by Manipulating Post-marketing Data? "IndyWatch Feed Health"

09-17-Infanrix-hexa-Vaccine_Featured_Image

Infant Deaths Following Vaccination: The Numbers Dont LieOr Do They?

by the Childrens Health Defense Team

National and international health agencies such as the Centers for Disease Control and Prevention (CDC), the European Medicines Agency (EMA) and the World Health Organization (WHO) routinely and emphatically claim that serious adverse events following vaccination are rare.

Nowhere is officialdoms minimization of vaccine risks more apparent than in these agencies position on vaccine-related deaths. The WHO, for example, states that so few deaths can plausibly be attributed to vaccines that it is hard to assess the risk statistically.

Nevertheless, once regulators have deemed that a given vaccine is safe enough to be licensed and widely marketed, vaccine manufacturers are supposed to do just thatthat is, continue to statistically assess a vaccines risks, including the risk of deathand regulators are supposed to carefully review the postlicensure data that pharmaceutical companies submit.

A 2017 commentary by India-based physicians Jacob Puliyel and C. Sathyamala in the Indian Journal of Medical Ethics describes a shocking dereliction of duty on the part of regulators who were presented with vaccine data carefully tailored to obscure serious risks.

Tackling concerns about infant deaths that have occurred following hexavalent vaccination in several European countries, the authors of the commentary show that GlaxoSmithKline (GSK) neglected to report to regulatory authorities that there was a statistically significant increased risk of sudden infant death in the four days after administration of its hexavalent vaccineand the reg...

Tuesday, 18 September

23:28

Huperzine A can significantly improve the cognitive function in patients with mild to moderate vascular dementia. "IndyWatch Feed Health"

PMID:  Cell Biochem Biophys. 2012 Jan ;62(1):55-8. PMID: 21833673 Abstract Title:  Treatment with Huperzine A improves cognition in vascular dementia patients. Abstract:  UNLABELLED: In the present study, we tested the efficacy and safety of Huperzine A in treatment of mild to moderate vascular dementia (VaD). This was a randomized, double-blinded, placebo-controlled study with 78 patients with mild to moderate VaD. The participants were randomized to receive either vitamin C (100-mg bid) as placebo (n = 39) or Huperzine A (0.1-mg bid) (n = 39) for 12 consecutive weeks. The mini-mental state examination (MMSE), clinical dementia rating (CDR), and activities of daily living (ADL) scores were used for the assessment of cognition. The assessments were made prior to treatment, and 4, 8, and 12 weeks of the treatment. The adverse effects of the treatment were also recorded. After 12 weeks of treatment, the MMSE, CDR, and ADL scores significantly improved in the Huperzine A group (P0.05 for all comparisons). No serious adverse events were recorded during the treatment.CONCLUSION: Huperzine A can significantly improve the cognitive function in patients with mild to moderate vascular dementia. Further, the medicament is safe.

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23:03

Intranasal administration of nasal gel huperzine A may represent a safe and noninvasive therapeutic strategy for the treatment of Alzheimer's disease. "IndyWatch Feed Health"

PMID:  Neuropsychopharmacology. 2011 Apr ;36(5):1073-89. Epub 2011 Feb 2. PMID: 21289607 Abstract Title:  Huperzine A activates Wnt/-catenin signaling and enhances the nonamyloidogenic pathway in an Alzheimer transgenic mouse model. Abstract:  Huperzine A (HupA) is a reversible and selective inhibitor of acetylcholinesterase (AChE), and it has multiple targets when used for Alzheimer's disease (AD) therapy. In this study, we searched for new mechanisms by which HupA could activate Wnt signaling and reduce amyloidosis in AD brain. A nasal gel containing HupA was prepared. No obvious toxicity of intranasal administration of HupA was found in mice. HupA was administered intranasally to-amyloid (A) precursor protein and presenilin-1 double-transgenic mice for 4 months. We observed an increase in ADAM10 and a decrease in BACE1 and APP695 protein levels and, subsequently, a reduction in A levels and A burden were present in HupA-treated mouse brain, suggesting that HupA enhances the nonamyloidogenic APP cleavage pathway. Importantly, our results further showed that HupA inhibited GSK3/ activity, and enhanced the -catenin level in the transgenic mouse brain and in SH-SY5Y cells overexpressing Swedish mutation APP, suggesting that the neuroprotective effect of HupAis not related simply to its AChE inhibition and antioxidation, but also involves other mechanisms, including targeting of the Wnt/-catenin signaling pathway in AD brain.

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22:00

Dr. Ron Unfiltered Uncensored Episode 275 Current Medical News Omega 3/6 Ratio "IndyWatch Feed Health"

Dr. Ron who is a Fellow of the American Academy of Family Practice and a Charter member of the American Academy of Emergency Medicine and a licensed Acupuncturist is joined by Dr. Gerry and Dr. Dan to host this weekly podcast on the latest medical news and information We are not influenced by Big Pharma and will give you honest opinions on the news, medical devices and we have terrific guests. We have over 150 years of combined medical experience and are grateful to share it with you.  You can hear us on BlogTalkRadio, Stitcher, iTunes, GooglePlay, Alexa, and others. Reach us live at 347-989-8899   According to research conducted at Harvard University, omega-3 fatty acid deficiency is officially one of the top 10 causes of death in America, claiming the lives of up to 96,000 people each year. Out of the 12 dietary, lifestyle and metabolic risk factors examined in the study, omega-3 fatty acid deficiency ranked as the sixth highest killer of Americans.

21:34

Cochrane Collaboration Letter to Members Regarding Ousting "IndyWatch Feed Health"

Dear Cochrane members, These are extraordinary times and we find ourselves in an extraordinary situation. Your Board is always happy to answer questions about our decisions, and today is no different. We want to explain how we got here today....

20:47

Utah 2nd District Debate Interrupted by Vaccine Injury Comment "IndyWatch Feed Health"

From The Hill.com Man arrested for shouting into Utah Republican's mic at debaten. The comments are a ghastly display of ignorance and hatred. ### Police arrested a man Monday who interrupted a debate by shouting into Rep. Chris Stewart's (R-Utah)...

18:52

Hang in There, People. Will Be Hummin Very Soon "IndyWatch Feed Health"

Okay, everyone, getting Chipur back together after migrating to a new web host. Pretty tense experience, and as you can see, still a lot of features missing - but not for long! Hang in there, okay? The change was needed (and change is often difficult)...

14:56

Village of Potsdam to continue fluoridating the water "IndyWatch Feed Health"

POTSDAM The Village of Potsdam will continue to fluoridate its water.

After a long, and at times heated, discussion over the past year and a half, Village Board of Trustees has voted to continue the practice.

But before that, the people voiced their opinions one last time.

This is the water I drink. This is the water my children drink, Sean Corbett said.

Mr. Corbett said that he has consumed fluoridated water all his life and claimed he had suffered no adverse effects.

Several health professionals from Canton-Potsdam Hospital attended the meeting to proclaim that continuing fluoridation was for the good of the people. One such health care professional was Andrew Williams, an associate medical director.

Again, I would just assert that community water fluoridation has been proven to be safe, effective, economical and ethical. I think weve always agreed that fluoridation is effective in preventing dental decay, Mr. Williams said.

But, like in every other meeting where the public had been encouraged to express opinions on the matter, there were those who disagreed and wanted the practice of water fluoridation to end.

There has been no study that has proven that it is safe for the thyroid, that it is safe for the kidneys, safe for the brain many studies question that it is, Chelle LaClare said.

It had to end, however, and after over an hour of public comments, the board had to vote.

It was the last item on the agenda. Attendees sat patiently, eyes trained on the board of trustees. As Lori S. Queor, the village clerk, read off the resolution, the crowd watched in silence.

No, said Trustee Stephen J. Warr. I have concerns about the way things are done.

Mr. Warr said that he had reached out to Canton-Potsdam Hospital staff to ask about how efficient and effective the water fluoridation process was but said he had received a limited response.

Two employees from the hospital interrupted Mr. Warr in disagreement, but he said that he had simply wished for more information.

I thought it would progress further than just a response, Mr. Warr said.

Yes, board member Maggie M. McKenna said. I do believe that the best medicine is preventative.

She said that after all the research she had done over the past year, she wasnt an expert, and would instead defer to the health care professionals.

Aye, board member Abigail D. Lee said. Many thanks to all the people who came.

I am going to vo...

14:45

White City plant evacuated due to fluorine gas leak "IndyWatch Feed Health"

WHITE CITY, Ore. A gas leak and small fire shut down portions of West Antelope Road from Table Rock to Kirkland Road earlier Tuesday.

Multiple agencies responded to the Linde Specialty Gases plant around 9:15 a.m. when some fluorine gas leaked inside of a gas cabinet. When the fluorine hit the air, it sparked a small fire.

The facility was evacuated out of an abundance of caution as firefighters were dispatched to the scene.

Officials say although the gas is hazardous, it was contained to the cabinet.

Plant manager Brian Mattingly explained, It is toxic, but it was in a gas cabinet and the employees were not in the area and no one was in any danger.

The cause of the leak is still under investigation. There were no injuries reported.

*Original article online at https://kobi5.com/news/local-news/white-city-plant-evacuated-due-to-fluorine-gas-leak-86113/

See also

06:28

Argan Oil Benefits and Uses for Face, Skin and Hair (Science Based) "IndyWatch Feed Health"

Argan oil is a natural plant oil with amazing benefits for your skin and hair. Argan oil contains antioxidants, fatty acids, and anti-inflammatory properties. These beneficial compounds in argan oil help nourish your skin, soothe inflammation, reduce fine lines and wrinkles, keep your skin moisturized, and treat many skin conditions.

One of the benefits of using pure argan oil on your skin is that it doesnt block pores. Because it also reduces sebum levels, it means that argan oil is an excellent treatment for acne. The high fatty acid content reduces acne inflammation, helps clear your skin, and may prevent acne scarring.

Argan oil can also do wonders for your scalp and help keep your hair conditioned and looking shiny.

In this article, you will find out what science really says about the wonderful benefits of applying argan oil on your skin. You will also learn how to use this versatile natural oil to improve the appearance of your hair.

What Is Argan Oil?

Argan oil is made by extracting oil from the Argan nut that grows on the argan tree which grows in Morocco. Argan oil is sometimes called Moroccan oil or Moroccan argan oil. This is not an essential oil but can be used as a carrier oil to dilute essential oils for use in aromatherapy and skin care.

Argan oil is a cold-pressed oil that is mostly done by hand. This is one of the reasons why argan oil is so expensive. The good news is that to get the benefits of argan oil for your skin, you only need a small amount, and you may ditch many of your expensive skin care products.

Although you can use it as a food, most people are interested in Argan oils amazing properties for your hair and skin.

Research into the medicinal compounds of argan oil shows that it is rich in monounsaturated, polyunsaturated, and saturated acids. Oleic acid and linoleic acid are the main fatty acids in argan oil. (1)

100% Argan oil is also a rich source of antioxidants. Argan oil benefits come from naturally-occurring polyphenols and other compounds that kill off free radicals from the skin. (2) Polyphenols are plant-based antioxidants that help protect the skin and prevent DNA cell damage. (3)

Many of the argan oil benefits for your skin and hair come from its high vitamin E content (tocopherol). (1) Studies have shown that vitamin E in cosmetic products help to reduce signs of a...

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