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Friday, 13 April

04:27

10 Unneeded Healthcare Treatments "IndyWatch Feed Health"

Doctors are often criticized for prescribing unneeded tests and procedures that harm more than they help and add to medical costs that could otherwise be avoided. Diagnostic tests are better than ever but they pick up conditions that might be perfectly harmless, forcing us to rethink when things are best left alone.

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Thursday, 12 April

20:42

Video: Mudslide Survival "IndyWatch Feed Health"

Video: Mudslide Survival Snowmelt and Spring rains can saturate the ground and destabilize the substrate, leading to what is known as a debris flow, mudslide, or landslide. When communities establish themselves on or at the bases of slopes, they are at risk for being in the midst of a river of, essentially, wet concrete. To avoid injury and loss of life, its important to recognize an impending mudslide and what you can do to shore up your property to defend

[... Continue Reading]

19:25

The Shocking Impact of TV on a Childs Brain "IndyWatch Feed Health"

By Heather CallaghanEditor

What happens to the minds of children who are exposed to television?

This is an important question to answer because children between the ages of 2-11 watch an average of over 25 hours of television per week. Thats a part-time job. And TV is basically an electronic babysitter due to its pacifying effect. Whats really going on?

And is it possible for educational technology to inappropriately stimulate and harm the developing childs brain?

this is important because were technologizing childhood today in a way that is previously unprecedented. Dimitri Christakis

Forty years ago, children began watching some television at age four (like the soothing Mr. Rogers).

Now they start big screen time as infants with rapid, high stimulation (like Baby Einstein and Powerpuff Girls).

Does modern TV precondition the mind to expect high levels of stimulation which leads to inattention and developmental problems later on?

...

19:19

See Which Produce Has the Most Pesticides in EWGs 2018 Dirty Dozen List "IndyWatch Feed Health"

By Anna Hunt

Almost everything we eat in the conventional diet is subject to manifold doses of chemicals. Agricultural producers often spray vegetables and fruits with 10-15 sprays, such as pesticides, fungicides, and herbicides, during the growing season. And thats considered the norm!

In total about seven billion pounds of pesticides are used annually worldwide. This includes agriculture and other industries. For example, modern building practices employ pesticides for wood preservation. But what Im trying to do is make a point: if youre buying conventional, non-organic food, you are eating these chemicals.

Its very likely that ingesting argochemicals diminishes the benefits of eating lots of fresh fruits and vegetables. Thats why, it is important that you do whatever you can to lessen your exposure to these chemicals.

Unfortunately, its more expensive to buy organics. Therefore, its best to know which produce has the most pesticides. To help you make informed choices at the store, the Environmental Working Group publishes an annual report of what produce get the most agrochemical action. They also offer insight into which fruits and vegetables are fairly clean.

Without further ado, heres the Dirty Dozen list and the Clean Fifteen list from the EWGs 2018 Shoppers Guide to Pesticides in Produce :

...

18:53

If Youre Worried About Bacteria On Prep Surfaces, Use Oregano Oil "IndyWatch Feed Health"

By Karen Foster

Risk of food poisoning from contaminated food surfaces may be reduced by using oregano oil to help kill bacteria, new research suggests.

Oregano is an important culinary and medicinal herb that has been used in medicine and cooking for thousands of years with a number of health benefits. It is a species of Origanum, belonging to the mint family (Lamiaceae). It is an indispensable spice in Turkish, Greek, Portuguese, Spanish, Latin American and Italian cuisine, oregano is the must-have ingredient in tomato sauces and pairs well with capers and olives.

It is one of the top five spices in the world with one of the highest ORAC (Oxygen Radical Absorbance Capacity) scores meaning it will more effectively neutralize free radicals. It is a powerful antimicrobial.

18:24

Propranolol: Girl Becomes Second Teen to Die After Taking Beta Blockers "IndyWatch Feed Health"

The recent tragic death of a teenage girl has been linked to anti-anxiety medications known as beta blockers. Now, from pained parents to pressured politicians, people are calling to put an end to these potentially life-taking drugs. Unfortunately, individuals living with mental health issues will often take risk-filled, synthetic drugs that usually only mask the... View Article

The post Propranolol: Girl Becomes Second Teen to Die After Taking Beta Blockers appeared first on Healthy Holistic Living.

18:18

Why Ayahuasca Is So Effective At Treating Depression "IndyWatch Feed Health"

Ayahuasca depression

By Dylan Charles

Some great number of years back a maniacal psychiatrist wanted me to hop on the antidepressant bus. I asked him for how long I might need to be on the pills, to which he replied, Forever.

You see, according to this esteemed professional I had a chemical imbalance that would require the ongoing supplementation of mass-produced chemicals into my body and brain. It was not my fault, he suggested, just bad luck in the procurement of serotonin, he supposed.

Turns out he was dead wrong. And lucky for me, I was able to muster the courage to dump his free-sample pills in the trash and pursue a different healing path.

Instead of psychotropic drugs, what I personally needed was exercise, a better diet, and better lifestyle choices. I also needed to think about my purpose in life and move in a direction that made it possible, and then to experience the feeling of success in accomplishing small goals and realizing dreams along the way. I also really needed deeper meaning in my life, better connection with people and to mother nature, and a greater sense of community.

Along this path I was called to journey with ayahuasca, and my experiences with this sacred medicine helped me to understand the healing process I was going through at that time. Most importantly, though, ayahuasca helped me to recognize that I was free to allow myself to be healed so I could get back to the good business of living life.

Having direct personal experiences, I know exactly how effective this medicine is in treating depression, although its not something easily put into...

18:14

Experts Share Testimonials On Chemtrails, Heavy Metal Contamination "IndyWatch Feed Health"

Troy Phillipson, a naturopath at Abundant Life Wellness Center in Milwaukee, routinely sends out hair samples for analysis. One startling thing he has noticed is the increasing levels of aluminum the labs are sending back.[1] (And youre all well aware of the dire health risks of aluminum exposure.) I believe it is time to get... View Article

The post Experts Share Testimonials On Chemtrails, Heavy Metal Contamination appeared first on Healthy Holistic Living.

18:09

Antioxidant and cancer chemopreventive activities of cistus and pomegranate polyphenols. "IndyWatch Feed Health"

PMID:  Acta Pol Pharm. 2017 Mar ;74(2):688-698. PMID: 29624275 Abstract Title:  ANTIOXIDANT AND CANCER CHEMOPREVENTIVE ACTIVITIES OF CISTUS AND POMEGRANATE POLYPHENOLS. Abstract:  Polyphenol rich extracts obtained from cistus herb (Cistus incanus L.) and pomegranate peel (Punica granatum L.) exhibited significant antioxidant activity in V79 cell culture (Chinese hamster lung fibroblasts) -cistus extract reduced intracellular content of reactive oxygen species (ROS) by 30-40% and pomegranate extract by 29-36%. In human breast (MCF-7) and colon (LOVO) cancer cell lines cistus and pomegranate extracts decreased cancer cell growth both in drug-sensitive cells by 15-30% and in drug resistant (doxorubicin-resistant; DX) sublines by 5-20%. However, the extracts did not influence on cell growth%f normal hamster fibroblast cultures (V79). The extracts induced apoptosis in the tested cancer cell lines. Significantly higher proapoptotic impact of the extracts was observed in drug-sensitive than in drug-resistant sublines. The results suggest potential usefulness of the tested polyphenol rich extracts in people exposed to oxidative stress. Their potential use as adjuvant therapy of human cancers needs further studies.

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17:20

Good News: FAN benefactor agrees to boost our numbers "IndyWatch Feed Health"

Good News! One of FANs long-time benefactors is prepared to help boost the number of supporters donating to our TSCA Legal Fund for our lawsuit against the EPA.* FAN will receive $250 when we reach 350 donors, $500 when we reach 400 donors, $250 when we reach 450 donors and $1000 when we reach 500 donors. All of this to help us increase the number of our supporters in our legal team.

You, and any of your family members, can join that team by donating $10 or more to our legal fund.

Currently our total stands at $46,742 from 308 donors. Thanks to everyone who has donated so far and for everything else you and they are doing to end the reckless practice of water fluoridation.

When years from now historians write about the peculiar practice of deliberately adding a known neurotoxic substance, that is also a known endocrine disruptor, to the public drinking water, while health agencies cheered on and the major newspapers remained silent, they will find that there were individuals like you who said no, who organized against huge odds, to end this practice. Such a victory will be seen as a victory for community action, scientific integrity, and the legal system.

We hope that you will continue to be part of that community action.

Our goal is to raise $75,000 by May 31. If we make that deadline then we have another long-time benefactor and one non-profit organization that have each pledged to donate $75,000 to yield a healthy legal fighting fund of $225,000. Ideally, we would like the burden to be shared by a 1000 people.

How to donate

  • Online at our secure server.
  • Or by Check, payable to the Fluoride Action Network. Send your check to:
    Fluoride Action Network
    c/o Connett
    104 Walnut Street
    Binghamton NY 13905

On behalf of the FAN team, thank you.

...

17:19

Daily consumption of mahanimbine and thereby curry leaves may alleviate development of high fat diet-induced metabolic alterations. "IndyWatch Feed Health"

PMID:  Biofactors. 2017 Mar ;43(2):220-231. Epub 2016 Sep 24. PMID: 27663177 Abstract Title:  Effect of mahanimbine, an alkaloid from curry leaves, on high-fat diet-induced adiposity, insulin resistance, and inflammatory alterations. Abstract:  Spices and condiments, small but an integral part of the daily diet, are known to affect physiological functions. This study evaluated the effects of mahanimbine, a major carbazole alkaloid from Murraya koenigii (curry leaves), against progression of high-fat diet (HFD)-induced metabolic complications in mice (male and female). Mahanimbine at 2 mg/kg (HFD+LD) and 4 mg/kg (HFD+HD) of body weight was administered daily along with HFD feeding for 12 weeks. At the end of the study, male HFD+LD and HFD+HD groups showed 51.703.59% and 47.373.73% weight gain, respectively, as compared with 71.026.04% in HFD fed mice whereas female HFD+LD and HFD+HD groups showed 24.311.68% and 25.102.61% weight gain as compared with HFD group with 36.693.60% of weight gain. Mahanimbine prevented HFD-induced hyperlipidemia and fat accumulation in adipose tissue and liver along with therestricted progression of systemic inflammation and oxidative stress. Moreover, mahanimbine treatment improved glucose clearance and upregulated the expression of insulin responsive genes in liver and adipose tissue. Male and female mice showed different traits in development of HFD-induced metabolic disturbances; however, mahanimbine treatment exerted similar effects in both the sexes. In addition, mahanimbine lowered the absorption of dietary fat resulting in dietary fat excretion. In conclusion, daily consumption of mahanimbine and thereby curry leaves may alleviate development of HFD-induced metabolic alterations. 2016 BioFactors, 43(2):220-231, 2017.

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17:07

Carbazole alkaloids from Murraya koenigii trigger apoptosis and autophagic flux inhibition in human oral squamous cell carcinoma cells. "IndyWatch Feed Health"

PMID:  J Nat Med. 2017 Jan ;71(1):158-169. Epub 2016 Sep 28. PMID: 27680541 Abstract Title:  Carbazole alkaloids from Murraya koenigii trigger apoptosis and autophagic flux inhibition in human oral squamous cell carcinoma cells. Abstract:  Carbazole alkaloids, a major constituent of Murraya koenigii (L.) Sprengel (Rutaceae), exhibit biological effects such as anticancer activity via the induction of apoptosis, and they represent candidate chemotherapeutic agents. Oral squamous cell carcinoma (OSCC) is the most prevalent cancer of the oral cavity and a growing and serious health problem worldwide. In this study, we investigated the anticancer properties and mechanisms of action of two carbazole alkaloids derived from M. koenigii leaves, mahanine and isomahanine, in the OSCC cell line CLS-354. At 15 M, mahanine and isomahanine were cytotoxic to CLS-354 cells, triggering apoptosis via caspase-dependent and -independent mechanisms. Autophagosomes, visualised using monodansylcadaverine (MDC) labelling, were numerous in carbazole alkaloid-treated cells. Mahanine and isomahanine markedly inducedthe expression of the autophagosome marker microtubule-associated protein 1 light chain 3, type II (LC3B-II). Genetic and chemical inhibition of autophagy via silencing of the Autophagy protein 5 gene and exposure to bafilomycin A1 (BafA1), respectively, did not arrest carbazole alkaloid-induced apoptosis, indicating that it occurs independently of autophagic activation. Surprisingly, both carbazole alkaloids caused increased accumulation of p62/sequestosome1 (p62/SQSTM1), with coordinated expression of LC3B-II and cleaved caspase-3, suggesting inhibition of autophagic flux. Our results suggest that inhibition of autophagic flux is associated with carbazole alkaloid-induced apoptosis. Our findings provide evidence of a novel cytotoxic action of natural carbazole alkaloids and support their use as candidate chemotherapeutic agents for the treatment of OSCC.

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17:02

This study validates the ethnopharmacological use of M. koenigii leaves in the management of anxiety disorders. "IndyWatch Feed Health"

PMID:  J Ethnopharmacol. 2016 Dec 4 ;193:706-711. Epub 2016 Oct 11. PMID: 27737817 Abstract Title:  Isolation, characterization and quantification of an anxiolytic constituent - mahanimbine, from Murraya koenigii Linn. Spreng Leaves. Abstract:  ETHNOPHARMACOLOGICAL RELEVANCE: Leaves of M. koenigii Linn. Spreng (Rutaceae) have been used as traditional medicine for anxiety disorders. Aim of the study was to isolate antianxiety principle(s) from the leaves of M. koenigii using bioactivity guided approach.MATERIAL AND METHODS: Hydroalcoholic extract of M. koenigii leaves was prepared using soxhlet apparatus, and the same was evaluated for antianxiety activity at 250, 500 and 750mg/kg, po, using Elevated plus-maze (EPM). The extract was further partitioned successively with pet ether, chloroform, ethyl acetate and 1-butanol. All the fractions were evaluated for antianxiety activity. The bioactive ethyl acetate fraction was column chromatographed to get 5 fractions (F-F). All the fractions were evaluated for antianxiety activity using EPM. A pure compound, separated out from Fwas characterized using standard spectroscopic techniques, and its anxiolytic activity was evaluated using EPM. Antianxiety activity of isolated compound was further evaluated using Actophotometer and m-CPP induced anxiety model. TLC-densitometric method was developed to quantify mahanimbine in the plant.RESULTS: The present study resulted in the isolation of mahanimbine, which exhibits potent antianxiety activity at 3mg/kg, and the activity was statistically comparable to that of diazepam (2mg/kg). The developed TLC-densitometric method is specific, linear, precise, accurate, repeatable and robust.CONCLUSIONS: This study validates the ethnopharmacological use of M. koenigii leaves in the management of anxiety disorders. Mahanimbine is responsible for the antianxiety effect of M. koenigii leaves.

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17:00

Authors retract heart disease paper for nonscientific reason "IndyWatch Feed Health"

Researchers have retracted a 2018 paper about the genetic underpinnings of heart disease from the FASEB Journal and its not entirely clear why. The paywalled retraction notice simply cites a nonscientific reason. Cody Mooneyhan, the director of publications at the journal, declined to provide further details, and the authors have provided different accounts of Continue reading Authors retract heart disease paper for nonscientific reason

16:53

Inhibition of quorum-sensing-controlled virulence factors of Pseudomonas aeruginosa by Murraya koenigii essential oil. "IndyWatch Feed Health"

PMID:  J Med Microbiol. 2016 Dec ;65(12):1528-1535. Epub 2016 Nov 3. PMID: 27902410 Abstract Title:  Inhibition of quorum-sensing-controlled virulence factors of Pseudomonas aeruginosa by Murraya koenigii essential oil: a study in a Caenorhabditis elegans infectious model. Abstract:  The global emergence of antibiotic-resistant strains of Pseudomonas aeruginosa poses a major threat in both hospital environments and the community. P. aeruginosa is an opportunistic human pathogen, and it also infects a wide range of model organisms including the nematode Caenorhabditis elegans. Quorum sensing (QS) mediates cell-to-cell communication in bacteria and has an important role in regulating virulence genes, antibiotic resistance and biofilm formation, which are crucial for establishment of the infection. Expression of many virulence factors such as pyocyanin and proteases in P. aeruginosa is under the control of the QS system, and are mediated by small molecules such as acyl homoserine lactones. Thus, interfering with the QS system would provide alternative ways of controlling the pathogenicity. Murraya koenigii is a medicinal plant widely used in India. The present study investigated the in vivo inhibitory activity of M. koenigii essential oil (EO) on QS-controlled virulence factors of P. aeruginosa PAO1 using C. elegans. M. koenigii EO significantly inhibited the pyocyanin production and staphylolytic LasA activity of P. aeruginosa PAO1. As compared to the control group with 100% killing of C. elegans, M. koenigii EO was able to rescue an average of 60% of C. elegans from death due to the toxic effect of P. aeruginosa. Thus, the present study suggests the anti-QS potential of M. koenigii EO which therefore can be considered as a future therapeutic agent for management of P. aeruginosa-mediated infections.

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16:40

This study demonstrates that inhibition of the proteasome is an important biological activity of M. koenigii alkaloids. "IndyWatch Feed Health"

PMID:  J Med Food. 2016 Dec ;19(12):1155-1165. PMID: 27982755 Abstract Title:  Cytotoxicity and Proteasome Inhibition by Alkaloid Extract from Murraya koenigii Leaves in Breast Cancer Cells-Molecular Docking Studies. Abstract:  Murraya koenigii (curry tree) leaves are rich in bioactive compounds such as flavonoids, alkaloids, and coumarins. Alkaloids from M. koenigii leaves have antianalgesic, antiulcerogenic, antiobesity, and antitumor activities. In this study, we tested the cytotoxic and proteasome-inhibitory potential of a total alkaloid extract (TAE) from M. koenigii leaves in the breast cancer cell line MDA-MB-231. The TAE decreased cell viability with an ICof 14.4g/mL and altered growth kinetics of breast cancer cells. TAE (32g/mL) arrested cells (35%) in the"S"phase of the cell cycle and induced apoptosis. The 26S proteasome, a multicatalytic protease complex, promotes tumor cell proliferation and protects tumor cells from apoptosis. The TAE and mahanine, a carbazole alkaloid present in M. koenigii leaves, preferentially inhibited the trypsin-like, but not the chymotrypsin-like proteolytic activity of the proteasome with an ICof 162g/mL and 287M, respectively. In silico analysis of 26 compounds from M. koenigii leaves revealed significant docking scores for mahanine and two other carbazole alkaloids with the 2 and 5 subunits of the catalytic 20S proteasome. Taken together, this study demonstrates that inhibitionof the proteasome is an important biological activity of M. koenigii alkaloids, which may lead to cancer cell death.

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16:20

The anti-colon cancer activity of Murraya koenigii leaves is due to the constituent murrayazoline. "IndyWatch Feed Health"

PMID:  Biomed Pharmacother. 2017 Sep ;93:510-521. Epub 2017 Jul 1. PMID: 28675857 Abstract Title:  Anti-colon cancer activity of Murraya koenigii leaves is due to constituent murrayazoline and O-methylmurrayamine A induced mTOR/AKT downregulation and mitochondrial apoptosis. Abstract:  In recent years, many alkaloids of plant origin have attracted great attention due to their diverse range of biological properties including anti-hyperglycemic, anti-oxidant, anti-inflammatory, anti-diabetic and anti-tumor activity. Herein, the pyranocarbazole alkaloids were isolated from leaves of Murraya koenigii and their anti-cancer potential was investigated in different cancer cell lines. Among all tested compounds, murrayazoline and O-methylmurrayamine A demonstrated potent anti-cancer activity against DLD-1 colon cancer cells with the ICvalues of 5.7M and 17.9M, respectively, without any non-specific cytotoxicity against non-cancer HEK-293 and HaCaT cells. Further, studies of pure compounds revealed that the anti-cancer activity of compounds corresponds with altered cellular morphology, cell cycle arrest in G2/M phase, reactive oxygen species level and mitochondrial membrane depolarization of colon cancer cells. In addition, these compounds activated caspase-3 protein and upregulated Bax/Bcl-2 protein expression ratio leading to induction of caspase-dependent apoptosis in DLD-1 cells. These event induced by carbazole alkaloids also coincides with downregulation of Akt/mTOR suggesting downstream targeting of cell survival pathway. Thus, our in vitro studies not only provided scientific basis of the use of M. koenigii leaves in the traditional Indian Ayurveda medicines, but also expands possibilities of medicinal uses of M. koenigii leaves against colon cancer. Particularly, these findings will help in further investigating murrayazoline and O-methylmurrayamine A or their improvised derivatives as new therapeutics for the treatment of colon cancer.

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16:06

Pyranocarbazoles from Murraya koenigii (L.) Spreng. as antimicrobial agents. "IndyWatch Feed Health"

PMID:  Nat Prod Res. 2018 Feb ;32(4):430-434. Epub 2017 Apr 3. PMID: 28368664 Abstract Title:  Pyranocarbazoles from Murraya koenigii (L.) Spreng. as antimicrobial agents. Abstract:  The bioassay guided fractionation of methanolic extract of Murraya koenigii (L.) Spreng. leaves resulted in the isolation of seven pyranocarbazoles. These were evaluated against four bacterial strains and ten Candida sp. including two matched pair of fluconazole sensitive/resistant clinical isolates. Out of seven, three i.e. Koenine (mk279), Koenigine (mk309) and Mahanine (mk347) exhibited significant antibacterial activity MIC90 3.12-12.5 g/mL against bacterial strains Streptococcus aureus and Klebsiella pneumonia compared with standard drug Kanamycin MIC90 12.5 g/mL. However, only mk309 was found active against variety of Candida species MIC90 12.5-100 g/mL. It was observed that hydroxylation at C-6 and C-7 positions in the studied pyranocarbazoles activate the bioactivity. Simultaneously, decrease in Log P value compares with -H and -O-CH3 substituted derivatives. The study is focused on selective antifungal and antibacterial activity of pyranocarbazoles on bacterial strains S. aureus, K. pneumonia and variety of Candida species with structure activity relationship observations.

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15:59

Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii. "IndyWatch Feed Health"

PMID:  Drug Des Devel Ther. 2017 ;11:103-121. Epub 2016 Dec 28. PMID: 28096658 Abstract Title:  Anticancer and anti-inflammatory activities of girinimbine isolated from. Abstract:  Therapy that directly targets apoptosis and/or inflammation could be highly effective for the treatment of cancer.is an edible herb that has been traditionally used for cancer treatment as well as inflammation. Here, we describe that girinimbine, a carbazole alkaloid isolated from, induced apoptosis and inhibited inflammation in vitro as well as in vivo. Induction of apoptosis in human colon cancer cells (HT-29) by girinimbine revealed decreased cell viability in HT-29, whereas there was no cytotoxic effect on normal colon cells. Changes in mitochondrial membrane potential, nuclear condensation, cell permeability, and cytochrome c translocation in girinimbine-treated HT-29 cells demonstrated involvement of mitochondria in apoptosis. Early-phase apoptosis was shown in both acridine orange/propidium iodide and annexin V results. Girinimbine treatment also resulted in an induction of G0/G1 phase arrest which was further corroborated with the upregulation of two cyclin-dependent kinase proteins, p21 and p27. Girinimbine treatment activated apoptosis through the intrinsic pathway by activation of caspases 3 and 9 as well as cleaved caspases 3 and 9 which ended by triggering the execution pathway. Moreover, apoptosis was confirmed by downregulation of Bcl-2 and upregulation of Bax in girinimbine-treated cells. In addition, the key tumor suppressor protein, p53, was seen to be considerably upregulated upon girinimbine treatment. Induction of apoptosis by girinimbine was also evidenced in vivo in zebrafish embryos, with results demonstrating significant distribution of apoptotic cells in embryos after a 24-hour treatment period. Meanwhile, anti-inflammatory action was evidenced by the significant dose-dependent girinimbine inhibition of nitric oxide production in lipopolysaccharide/interferon-gamma-induced cells along with significant inhibition of nuclear factor-kappa B translocation from the cytoplasm to nucleus in stimulated RAW 264.7 cells. Girinimbine was also shown to have considerable antioxidant activity whereby 20g/mL of girinimbine was equivalent to 82.171.88 M of Trolox. In mice with carrageenan-induced peritonitis, oral pretreatment with girinimbine helped limit total leukocyte migration (mainly of neutrophils), and reduced pro-inflammatory cytokine levels (interleukin-1beta and tumor necrosis factor-alpha) in the peritoneal fluid. These findings strongly suggest that girinimbine could act as a chemopreventive and/or chemotherapeutic agent by inducing apoptosis while suppressing inflammation. There is a potential for girinimbine to be further investigated for its applicability in treating early stages...

15:55

British Health Experts Investigating Excess Prescription Deaths "IndyWatch Feed Health"

Some of Britains top health experts are concerned that the overprescription of drugs is becoming an epidemic. And they now believe this epidemic is causing excess deaths. Theyve now suggested that a Chilcot style inquiry...

The post British Health Experts Investigating Excess Prescription Deaths appeared first on Vaxxter.

15:44

The present study reveals the protective role of M. koenigii extract against cyclophosphamide induced nephrotoxicity. "IndyWatch Feed Health"

PMID:  Asian Pac J Trop Med. 2017 Aug ;10(8):808-812. Epub 2017 Aug 24. PMID: 28942830 Abstract Title:  Nephroprotective effect of Murraya koenigii on cyclophosphamide induced nephrotoxicity in rats. Abstract:  OBJECTIVE: To evaluate the nephroprotective effect of defatted methanolic extract and aqueous extract of Murraya koenigii (M. koenigii) against cyclophosphamide drug.METHODS: Nephrotoxicity was induced by cyclophosphamide in 7 days at 150 mg/kg body weight through intraperitoneal route in rat model. Nephroprotective activity of M. koenigii extract (100 mg/kg and 200 mg/kg in intraperitoneal route) was measured, including nephrological source, oxidative stress parameters like superoxide dismutase, glutathione, the lipid peroxide and in vivo assay like blood urea nitrogen, creatinine were determined and analyzed by One way analysis of variance followed by Tukey's test.RESULTS: The study result showed that important phytochemicals such as carbohydrates, flavonoids, tannin, alkaloids, glycosides, protein and steroids were found to be present in the extract of M. koenigii. The renal function markers like blood urea nitrogen and creatinine level were found to be decreased significantly by M. koenigii extract treatment. A significant difference was found to be at P 

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15:29

NIHs Drunken (And Corrupt) Science "IndyWatch Feed Health"

The National Institutes of Health (NIH) sought funding for an alcohol studyfrom the alcohol industry.

From the Washington Examiner:

Scientists and officials from the National Institutes of Health worked to solicit donations from the alcohol industry for a study they said would likely conclude that moderate drinking is healthy, according to a new report.

The report said that presentations by NIH officials gave the alcohol industry an opportunity to look at how the studies were being designed and to see who was conducting the investigation.

Comment: This is government cronyism at its finest, echoing our previous coverage of the Centers for Disease Control and Preventions ties to Coca-Cola, and the USDAs support of the biotech industry. More reasons that the government cannot be trusted when it comes to the latest scienceespecially science about what is and what is not healthy.

14:38

Former Jersey Assemblywoman Says Vaccine Mandates Problematic "IndyWatch Feed Health"

New Jerseys tougher vaccine exemption bill (A-3818) is nearing a vote potentially as early as Thursday. The bill would dramatically tighten rules regarding religious and medical exemptions, including for the HPV vaccine. Even in cases...

The post Former Jersey Assemblywoman Says Vaccine Mandates Problematic appeared first on Vaxxter.

14:00

Yosemite Sam: Bunny nemesisand renowned scientist who nominates a journalist for a Nobel? "IndyWatch Feed Health"

If youre unfamiliar with the work of Tom Spears, a reporter at the Ottawa Citizen, you have missed some clever lampooning of fake journals. But that work has not gone unnoticed in some circles, apparently: In the not-so-cleverly named journal Significances of Bioengineering & Biosciences, whose publishers motto is Wings To The Research, a researcher Continue reading Yosemite Sam: Bunny nemesisand renowned scientist who nominates a journalist for a Nobel?

12:08

Our Brave New World: Pharma's Political Straw Men, Lies and Censorship "IndyWatch Feed Health"

by John Stone We are reaching a critical point (and historic moment) which resembles in some ways both WMD and the banking crisis of 2008: the burden of scientific evidence and personal testimony weighs heavily against the industry (everyone has...

11:42

Nothing To See Here "IndyWatch Feed Health"

By Anne Dachel Numbers mean nothing. Cost is meaningless. NO MATTER HOW BAD THINGS GET IN SCHOOLS, THERE WILL NEVER BE A REAL PROBLEM. Behavior is out-of-control. Special education is exploding at the seams. Mental health concerns are a more...

07:15

Grow Quinoa in Your Garden "IndyWatch Feed Health"

Source: Grow Quinoa in Your Garden For more content like this visit REALfarmacy.com.

Due to its nutritious content, and good taste, quinoa has become a common household food in the United States. Learn how to grow your own quinoa and never purchase it again.   Quinoa seeds are very high in protein and have the ability to lower LDL cholesterol.This gluten free grain-like crop is great for heart []

Source: Grow Quinoa in Your Garden Learn more at REALfarmacy.com - Healthy News and Information.

07:00

Help Detoxify Your Body With Stinging Nettle "IndyWatch Feed Health"

Nettle (Urtica dioica) is a common sight in backyards and gardens, although its often weeded out and thrown aside, sometimes even avoided because of its stinging properties. But remember that whenever you discard this weed, know that youre also ignoring the health benefits that you can get from it.

The first documented use of this herb was when Roman soldiers battled the cold by rubbing the leaves on their arms to induce inflammation and irritation. It has now spread across the world and has been used by medical practitioners since the 19th century because of its abundance of chemicals and compounds that can help the body function optimally.

But even though the medicinal importance of nettle has been established through numerous studies, its image is still usually overshadowed by the fact that its still an unwelcome member of your garden.1

Nettle plant can be differentiated from other plants through its leaves. The nettle leaf has an ovate shape with deeply serrated edges. These leaves also have long stinging hairs that inject chemicals into the skin when you accidentally touch or brush past them. These hairs often cause pain and inflammation in the affected area.2

Even though nettle is often avoided and deemed as a useless plant, it has been the subject of numerous studies that prove its worth. Continue reading to know more about the health benefits and uses of this common herb.

Nettle Benefits: What Can You Get From This Weed?

Nettle contains vitamins C and K, B vitamins, as well as minerals like calcium, magnesium and iron, to name a few.3 It also has amino acids and antioxidants, which may help fight free radicals.4 Here are a few more health benefits you can get from this herb:

Helps detoxify the body. Nettle is a diuretic, which means that it helps in flushing out harmful chemicals and excess liquids from the body. This herb has also been called a spring tonic, which is a substance intended to cleanse the body of toxins.5

Promotes healthy blood circulat...

How to Decrease Your Risk for Dementia by 90 Percent "IndyWatch Feed Health"

By Dr. Mercola

Staying fit is key to warding off many chronic diseases in later life, including those that may affect your brain. Worldwide, 47 million people are living with dementia. This is expected to increase to 75 million by 2030 and more than triple by 2050, according to the World Health Organization (WHO).1 Yet, you may be able to significantly slash your risk by taking steps to improve and maintain your cardiovascular fitness.

In fact, researchers from the University of Gothenburg in Sweden revealed that women with the highest cardiovascular fitness had an 88 percent lower risk of dementia than those with moderate fitness.2 Further, even maintaining average fitness is worthwhile, as women with the lowest fitness had a 41 percent greater risk of dementia than those of average fitness. Fitness, in this case, is not the same as exercise, and the study did not measure how often the women exercised.

Instead, it focused on cardiovascular fitness, as measured by a stepwise-increased maximal ergometer cycling test. Cardiovascular fitness can be a measure of how well blood is circulating to your heart and brain. Study author and physiotherapist Helena Horder told Time, "If the small blood vessels and circulation in the heart are OK, then the brain is also affected in a positive way by good small vessel circulation."3

Why Cardiovascular Fitness May Lower Dementia Risk

During the cycling test, women continued cycling as additional weight or resistance was added. When they became exhausted to the point that they couldn't continue, or the test had to be stopped due to changes seen on an electrocardiograph or in their blood pressure, that was considered to be their peak workload.

Overall, out of the 191 women in the test, 23 percent developed dementia during the 44-year study period. However, among those whose cycling test was interrupted before reaching peak workload, the percentage with dementia rose to 45 percent. "Many of those who interrupted the test at submax, very low watt level, probably had indications for a poor cardiovascular health status," Horder told CNN.

"This might indicate that processes in the cardiovascular system might be ongoing many decades before onset of dementia diagnosis."4 Further, past research has revealed that exercise prevents age-related shri...

Beets May Help Prevent Alzheimers Disease "IndyWatch Feed Health"

By Dr. Mercola

Beets have been shown to fight inflammation, lower blood pressure1,2 and aid detoxification. Studies also suggest they can help lower your risk for heart failure and stroke, and provide powerful benefits for your brain, largely due to their high nitrate content. Your body transforms nitrates into nitric oxide,3 which enhances oxygenation and has beneficial impacts on your circulatory and immune systems.

Nitric oxide4 is a soluble gas continually produced from the amino acid L-arginine inside your cells, where it supports endothelial function and protects your mitochondria. Nitric oxide also serves as a signaling or messenger molecule in every cell of your body. Many competitive athletes actually use beet juice for its nitric oxide-boosting benefits. Research shows raw beets may increase stamina during exercise by as much as 16 percent,5 courtesy of its nitric oxide boost.

Beets May Protect Against Development of Alzheimers Disease

Now, research presented at the 2018 American Chemical Societys meeting6 in New Orleans claims beets may also be a powerful ally in the fight against Alzheimers disease,7,8 the most severe and lethal form of dementia. As reported by The Atlanta Journal-Constitution:9

First they examined the possible cause of the condition. Although its unknown, doctors have previously pinpointed beta-amyloid, a sticky protein that can disrupt communication between the brain cells and neurons. When it clings to metals, such as copper or iron, the beta-amyloid peptides misfold and clump together, causing inflammation a...

04:02

Murraya koenigii aqueous leaf extract reduced the despair behaviour. "IndyWatch Feed Health"

PMID:  Anc Sci Life. 2017 Apr-Jun;36(4):215-219. PMID: 29269974 Abstract Title:  Anti-anxiety and Anti-depressant Like Effects ofin Experimental Models of Anxiety and Depression. Abstract:  Background: Presence of free radical scavenging activity in, commonly known as Curry leaves, has been shown in previous studies. Oxidative stress plays an important role in the development of various neurobehavioral disorders including anxiety and depression.Aim: The present study aimed to evaluate the effects ofin animal models of depression and anxiety.Materials and Methods: The effect of incremental doses ofaqueous leaf extract was evaluated on spontaneous motor activity (SMA), open arm incursions in elevated plus maze, and despair behaviour in forced swim (FST) and tail suspension (TST) tests as compared to control groups in Swiss albino mice.Results: 300 mg/kg, p.o. (MK300) and 400 mg/kg, p.o. (MK400) reduced the SMA count from 754 64.9 to 540 29 and 295 34 respectively, which was statistically significant. MK300 and MK400 reduced significantly the open arm count from 29 8.6 to 16 7 and 10 3.9, respectively. On FST, MK400 reduced the duration of immobility from 145.5 29 to 91 17.3, which was statistically significant. On TST, MK produced a dose-dependent decrease in the duration of immobility; however, it was statistically significant only with MK400.Conclusion: aqueous leaf extract reduced the despair behavior in experimental animal models, suggesting an anti-depressant like activity.extract also reduced spontaneous locomotor activity in a dose-dependent manner suggesting a sedative and/or anxiolytic effect though there wasn't any anxiolytic effect in the elevated plus maze test.

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03:27

Anti-influenza A virus effects of fructan from Welsh onion. "IndyWatch Feed Health"

PMID:  Food Chem. 2012 Oct 15 ;134(4):2164-8. Epub 2012 Apr 13. PMID: 23442670 Abstract Title:  Anti-influenza A virus effects of fructan from Welsh onion (Allium fistulosum L.). Abstract:  A fructan that acts as an anti-influenza A virus substance was isolated from hot water extract of the green leafy part of a Welsh onion (Allium fistulosum L.). The structure of the fructan was characterised and elucidated by chemical and spectroscopic analyses. The fructan was composed of terminal (21.0%) and 2,1-linked-D-Fruf residues (65.3%) with 1,6-linked -D-Glcp residues (13.7%). The molecular weight of the polysaccharide and polydispersity was estimated to be 1.510(3) and 1.18, respectively. Although the fructan did not show anti-influenza A virus activity in vitro, it demonstrated an inhibitory effecton virus replication in vivo when it was orally administered to mice. In addition, the polysaccharide enhanced the production of neutralising antibodies against influenza A virus. Therefore, the antiviral mechanism of the polysaccharide seemed to be dependent on the host immune system, i.e., enhancement of the host immune function was achieved by the administration of the polysaccharide. From our observations, the fructan from Welsh onions is suggested to be one of the active principles which exert an anti-influenza virus effect.

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03:20

These results suggest that an oral administration of the A. fistulosum mucus can enhance natural immunity. "IndyWatch Feed Health"

PMID:  Biosci Biotechnol Biochem. 2013 ;77(9):1809-13. Epub 2013 Sep 7. PMID: 24018671 Abstract Title:  Activation of immune responses in mice by an oral administration of bunching onion (Allium fistulosum) mucus. Abstract:  Bunching onion [Allium fistulosum L. (Liliaceae)] secretes mucus in the cavities of its green leaves. The effects of the mucus, which is consumed as food, were examined. The mucus augmented the production of tumor necrosis factor (TNF)- and monocyte chemotactic protein (MCP)-1 from RAW 264 cells and of interleukin (IL)-12 from J774.1 cells; however, extracts from green leaves and white sheaths did not. An oral administration of this mucus to mice augmented the immune functions of peritoneal cells by increasing TNF- and IL-12 production and phagocytosis. It also augmented interferon (IFN)- production from spleen cells and natural killer (NK) activity. These results suggest that an oral administration of the A. fistulosum mucus can enhance natural immunity.

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03:03

Activation of the antitumor immune system by onionin A1 might be an effective adjuvant therapy for patients with malignant tumors. "IndyWatch Feed Health"

PMID:  Chem Pharm Bull (Tokyo). 2017 ;65(3):209-217. PMID: 28250342 Abstract Title:  Antitumor Allium Sulfides. Abstract:  We examined the sulfides in onion (Allium cepa L.), Welsh onion (A. fistulosum L.), and garlic (A. sativum L.), and obtained three new thiolane-type sulfides (onionins A-A) from onion; two new thiabicyclic-type sulfides (welsonins A, A), together with onionins A-A, from Welsh onion; and six new acyclic-type sulfides (garlicnins L-1-L-4, E, and F), ten new thiolane-type sulfides (garlicnins A, B-B, C-C, K, and K), and three new atypical cyclic-type sulfides (garlicnins G, I, and J) from garlic. Acetone extracts showed the potential of these sulfides in inhibiting the polarization of M2 activated macrophages that are capable of suppressing tumor-cell proliferation. The effect of the thiolane-type sulfide of a major component, onionin A, on tumor progression and metastasis in both osteosarcoma and ovarian cancer-bearing mouse models was then examined. Tumor proliferation was depressed, and tumor metastasis was controlled by regulating macrophage activation. These results showed that onionin Ais an effective agent for controlling tumors in both in vitro and in vivo models, and that the antitumor effects observed in vivo are likely caused by reversing the antitumor immune system. Activation of the antitumor immune system by onionin Amight be an effective adjuvant therapy for patients with osteosarcoma, ovarian cancer and other malignant tumors. Based on these findings, pharmacological investigations will be conducted in the future to develop natural and healthy foods and anti-cancer agents that can prevent or combat disease.

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02:51

A. fistulosum extracts have potential as functional food materials for weight control in obesity. "IndyWatch Feed Health"

PMID:  BMC Complement Altern Med. 2018 Mar 20 ;18(1):105. Epub 2018 Mar 20. PMID: 29558911 Abstract Title:  Aqueous and ethanolic extracts of welsh onion, Allium fistulosum, attenuate high-fat diet-induced obesity. Abstract:  BACKGROUND: Allium fistulosum (Welsh onion) is a traditional medicinal plant used for the treatment of colds, influenza, abdominal pain, headache, and heart disease. This study evaluated the effects of A. fistulosum ethanolic extract (AFE) and aqueous extract (AFW) on body weight and other obesity-related parameters.METHODS: Male 8-week-old C57BL/6 J mice were fed either a standard chow diet (normal control) or a high-fat diet (HFD) either alone (HFD-control) or in combination with G. cambogia extract containing hydroxycitric acid (HCA, an herbal weight-loss supplement), conjugated linoleic acid (CLA, a weight-loss supplement), orlistat (a clinically available anti-obesity drug), AFW, or AFE (n=6 mice per group) for 6 weeks. At the end of 6 weeks, several body weight and obesity-related parameters were examined, including: liver and adipose weight, adipocyte size, serum lipid profiles, liver expression of adenosine monophosphate-activated protein kinase (AMPK), and adipose tissue expression of uncoupling protein 2 (UCP2).RESULTS: High-performance liquid chromatography showed that both AFE and AFW contain ferulic acid and quercetin. Oral administration of AFW and AFE to HFD-fed mice decreased body weight as well as liver and adipose tissue weight and adipocyte size. Serum lipid profiles and adiponectin levels were improved in HFD-fed mice treated with AFE but not AFW. However, both AFW and AFE significantly attenuated HFD-induced changes in serum leptin and insulin-like growth factor 1 levels, liver expression of AMPK, and adipose tissue expression of UCP2.CONCLUSIONS: The findings from this study suggest that A. fistulosum extracts have potential as functional food materials for weight control in obesity.

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02:38

Allium fistulosum attenuates the development of NAFLD. "IndyWatch Feed Health"

PMID:  Nutr Res Pract. 2018 Apr ;12(2):110-117. Epub 2018 Mar 22. PMID: 29629027 Abstract Title:  Ethanol extract ofinhibits development of non-alcoholic fatty liver disease. Abstract:  BACKGROUND/OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease and is closely associated with metabolic syndrome. In the present study, we observed the effect of ethanol extract of(EAF) on NAFLD and have suggested the possibility of using EAF as a natural product for application in the development of a treatment for NAFLD.MATERIALS/METHODS: The preventive effect on hepatic lipid accumulation was estimated by using an oleic acid (OA)-induced NAFLD modeland a Western diet (high-fat high-sucrose; WD)-induced obese mouse model. Animals were divided into three groups (n = 7): normal diet group (ND), WD group, and WD plus 1% EAF group.RESULTS: EAF reduced OA-stimulated lipid accumulation in HepG2 cells in the absence of cellular cytotoxicity and significantly blocked transcriptional activation of sterol regulatory element-binding protein 1 and fatty acid synthase genes. Subsequently, we investigated these effectsin mice fed either ND or WD in the presence or absence of EAF supplementation. In comparison to the ND controls, the WD-fed mice exhibited increases in body weight, liver weight, epididymal fat weight, and accumulation of fat in hepatocytes, and these effects were significantly attenuated by EAF supplementation.CONCLUSIONS: attenuates the development of NAFLD, and EAF elicits anti-lipogenic activity in liver. Therefore, EAF represents a promising candidate for use in the development of novel therapeutic drugs or drug combinations for the prevention and treatment of NAFLD.

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02:33

The Approved Monsanto-Bayer Merger Could Spell Disaster for a Budding Cannabis Industry "IndyWatch Feed Health"

By Phillip Schneider

After selling off enough assets to win anti-trust approval, the Department of Justice (DOJ) has approved a mega-merger between Monsanto and Bayer, two of the worlds leading chemical/biotech companies. Although polling has shown that over 90 percent of farmers are concerned about the merger, the DOJ and European Commission have given the green light for what is being called a Merger from Hell.

Not only will this merger result in less competition and reduced leverage for farmers, but it also paves the way for a de facto corporate takeover of the emerging cannabis industry through patent-pending genetically modified seeds.

The Justice Departments rubber stamping of these three seed mega-mergers transforms the already concentrated agrichemical and seed market, effectively reducing the number of competitors from six to three.  ~Wenonah Hauter, executive director of Food & Water Watch

02:24

Low adherence to the western and high adherence to the mediterranean dietary patterns could prevent colorectal cancer. "IndyWatch Feed Health"

PMID:  Eur J Nutr. 2018 Mar 26. Epub 2018 Mar 26. PMID: 29582162 Abstract Title:  Low adherence to the western and high adherence to the mediterranean dietary patterns could prevent colorectal cancer. Abstract:  PURPOSE: To assess if the associations found between three previously identified dietary patterns with breast, prostate and gastric cancer are also observed for colorectal cancer (CRC).METHODS: MCC-Spain is a multicase-control study that collected information of 1629 incident cases of CRC and 3509 population-based controls from 11 Spanish provinces. Western, Prudent and Mediterranean data-driven dietary patterns-derived in another Spanish case-control study-were reconstructed in MCC-Spain. Their association with CRC was assessed using mixed multivariable logistic regression models considering a possible interaction with sex. Risk by tumor site (proximal colon, distal colon, and rectum) was evaluated using multinomial regression models.RESULTS: While no effect of the Prudent pattern on CRC risk was observed, a high adherence to the Western dietary pattern was associated with increased CRC risk for both males [OR(95% CI): 1.45 (1.11;1.91)] and females [OR(95% CI): 1.50 (1.07;2.09)] but seem to be confined to distal colon [OR(95% CI): 2.02 (1.44;2.84)] and rectal [OR(95% CI): 1.46 (1.05;2.01)] tumors. The protective effect of the Mediterranean dietary pattern against CRC was observed for both sexes [males: OR(95% CI): 0.71 (0.55;0.92); females: OR(95% CI): 0.56 (0.40;0.77)] and for all cancer sites: proximal colon [OR(95% CI): 0.70 (0.51;0.97)], distal colon [OR(95% CI): 0.65 (0.48;0.89)], and rectum (OR(95% CI): 0.60 (0.45;0.81)].CONCLUSION: Our results are consistent with most of the associations previously found between these patterns and breast, prostate and gastric cancer risk and indicate that consuming whole fruits, vegetables, legumes, olive oil, nuts, and fish and avoiding red and processed meat, refined grains, sweets, caloric drinks, juices, convenience food, and sauces might reduce CRC risk.

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02:24

If You're Worried About Bacteria On Prep Surfaces, Use Oregano Oil "IndyWatch Feed Health"

Risk of food poisoning from contaminated food surfaces may be reduced by using oregano oil to help kill bacteria, new research suggests.

02:16

An improved diet is particularly important for individuals with a high genetic risk for NAFLD. "IndyWatch Feed Health"

PMID:  Gastroenterology. 2018 Mar 28. Epub 2018 Mar 28. PMID: 29604292 Abstract Title:  Improved Diet Quality Associates With Reduction in Liver Fat-Particularly in Individuals With High Genetic Risk Scores for Nonalcoholic Fatty Liver Disease. Abstract:  BACKGROUND & AIMS: Dietary modification has been recommended for treatment of nonalcoholic fatty liver disease (NAFLD), although it is not clear whether improving diet quality can prevent its development. We performed a prospective study to examine the association between diet quality change and change in liver fat change. We also examined the association between genetic risk score and liver fat change in individuals with different levels of diet quality change.METHODS: Our study included 1521 participants who attended the seventh and eighth examinations (1998-2001 and 2005-2008) of the second-generation cohort or attended the first and second examinations (2002-2005 and 2008-2011) of the third-generation cohort in the Framingham Heart Study. The self-administered semi-quantitative 126-item Harvard food frequency questionnaire was used to determine dietary intake in the year leading up to an examination. We assessed levels of liver fat using liver-phantom ratio (LPR) and computed tomography images from 2002 through 2005 and again from 2008 through 2011. LPR values are inversely related to liver fat-increased LPR indicates decreased liver fat. We examined associations of changes in 2 diet scores-the Mediterranean-style diet score (MDS) and Alternative Healthy Eating Index (AHEI)-with changes in liver fat and new-onset fatty liver. We evaluated interactions between diet score change and a weighted genetic risk score for NAFLD, determined based on multiple single nucleotide polymorphisms identified in genome-wide association studies of NAFLD. The primary outcome was change in LPR between baseline and follow-up measurement.RESULTS: For each 1-standard deviation increase in MDS, the LPR increased (meaning liver fat decreased) by 0.57 (95% CI, 0.27-0.86; P

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01:24

A closer adherence to the Mediterranean diet was associated with a better cognitive status. "IndyWatch Feed Health"

PMID:  J Am Coll Nutr. 2018 Apr 5:1-7. Epub 2018 Apr 5. PMID: 29621433 Abstract Title:  Mediterranean Diet and Cognitive Status in Free-Living Elderly: A Cross-Sectional Study in Northern Italy. Abstract:  OBJECTIVE: Few data are available on the Italian elderly population with regard to adherence to the Mediterranean diet (MD) and cognitive impairment. Our aim was to investigate adherence to the MD and its association with cognitive function in an Italian urban sample.METHODS: A cross-sectional study of 279 participants aged 65 years (80 men, 199 women) was carried out at a nutritional center. Adherence to the MD was evaluated using a 14-item questionnaire. Cognitive function was assessed with the Mini-Mental State Examination (MMSE).RESULTS: The clinical and nutritional assessments performed revealed 30.1% to have a dietary pattern in accordance with the MD; 13.6% had suspected or mild cognitive impairment (MMSE score 23). The MD pattern was associated with a lower risk of cognitive impairment (odds ratio [OR] = 0.39; 95% confidence interval [CI], 0.15-0.99; p = 0.045), as was the consumption of wine (OR = 0.37; 95% CI, 0.16-0.84; p = 0.018) and nuts (OR = 0.30; 95% CI, 0.13-0.69, p = 0.005). No association was found with other food groups.CONCLUSION: A closer adherence to the MD was associated with a better cognitive status. Further cohort studies and randomized controlled trials are warranted.

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01:11

High intake of magnesium may be associated with reduced risks of fatty liver disease and prediabetes. "IndyWatch Feed Health"

PMID:  Public Health Nutr. 2018 Apr 2:1-8. Epub 2018 Apr 2. PMID: 29607802 Abstract Title:  Intakes of magnesium, calcium and risk of fatty liver disease and prediabetes. Abstract:  OBJECTIVE: Obesity and insulin resistance play important roles in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Mg intake is linked to a reduced risk of metabolic syndrome and insulin resistance; people with NAFLD or alcoholic liver disease are at high risk of Mg deficiency. The present study aimed to investigate whether Mg and Ca intakes were associated with risk of fatty liver disease and prediabetes by alcohol drinking status.DESIGN: We analysed the association between Ca or Mg intake and fatty liver disease, prediabetes or both prediabetes and fatty liver disease in cross-sectional analyses.SETTING: Third National Health and Nutrition Examination Survey (NHANES III) follow-up cohort of US adults.SUBJECTS: Nationally representative sample of US adults in NHANES (n 13 489).RESULTS: After adjusting for potential confounders, Mg intake was associated with approximately 30 % reduced odds of fatty liver disease and prediabetes, comparing the highest intake quartile v. the lowest. Mg intake may only be related to reduced odds of fatty liver disease and prediabetes in those whose Ca intake is less than 1200 mg/d. Mg intake may also only be associated with reduced odds of fatty liver disease among alcohol drinkers.CONCLUSIONS: The study suggests that high intake of Mg may be associated with reduced risks of fatty liver disease and prediabetes. Further large studies, particularly prospective cohort studies, are warranted to confirm the findings.

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00:45

Ascorbic acid has a great therapeutic potential for amyloid disorders. "IndyWatch Feed Health"

PMID:  Int J Biol Macromol. 2018 Mar 27 ;114:666-678. Epub 2018 Mar 27. PMID: 29596935 Abstract Title:  Inhibition of amyloid fibril formation of lysozyme by ascorbic acid and a probable mechanism of action. Abstract:  Amyloid fibrillation of proteins and polypeptides and their deposition in cells and tissues is associated with a number of pathological states collectively known as amyloid disorders. Inhibition of protein misfolding and aggregation is thus of utmost importance in the prevention and treatment of such diseases. There is a growing interest in identification of small molecules that can bind to native monomeric proteins or their partially unfolded states, thereby stabilizing them and preventing or delaying them from undergoing amyloid fibril formation. Here we report the inhibitory effect of ascorbic acid, an essential dietary component richly present in many natural food items, on the amyloid fibrillation of hen egg white lysozyme, a model protein for amyloid formation. The effect was dose dependent with more than 80% inhibition occurring even at only a five-fold molar excess of ascorbic acid. TEM images show complete absence of fibrils in the presence of ascorbic acid. From our spectroscopic and computational characterization of ascorbic acid binding to HEWL, we propose that ascorbic acid binds to the aggregation prone beta domain of HEWL, stabilizes the partially unfolded conformation and prevents further conformational changes leading to fibrillation. Hence ascorbic acid has a great therapeutic potential for amyloid disorders.

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00:43

Pneumonia: Is It Contagious, Causes, Symptoms and Transmission "IndyWatch Feed Health"

Pneumonia is a bacterial, viral, or fungal infection of the lungs that can be contagious. If pneumonia is the result of a respiratory infection like the cold or flu virus, then pneumonia is infectious and can easily spread from person to person. Pneumonia can result in a mild to severe cough that may bring up phlegm. Droplets expelled from the mouth may contain contagious germs that can easily be passed on to other people.

Bacterial pneumonia and viral pneumonia are types of inflammatory lung infections that are contagious.

Although many types of pneumonia are spreadable, not all types of pneumonia are contagious. For example, noncontagious types of pneumonia include fungal pneumonia and aspiration pneumonia. Fungal pathogens can be breathed in from the environment and cause pneumonia but wont be transmissible between persons. Also, certain medical conditions can cause food, saliva, or foreign objects to get stuck in the lungs and cause inflammation with a chesty cough.

In this article, you will learn about contagious pneumonia and what can cause it. You will also find out what you can do to prevent catching pneumonia and when the lung infection is serious enough to see a doctor.

What is Pneumonia?

Pneumonia occurs when germs, microbes, or foreign objects infect the lungs, causing inflammation and chest discomfort. Infections causing pneumonia can affect anyone of any age.

According to researchers from the American Lung Association, pneumonia contagious and noncontagious describes the result of lung inflammation and is not a single disease. Inflammation of the lungs causes the air sacs to fill up with fluid, and this causes a cough as well as a possible fever and/or breathing difficulties.1

The American Lung Association also says that viral pneumonia can develop into bacterial pneumonia and can cause more severe lungs inflammation symptoms. A person is at risk of catching bacterial pneumonia because of old age, if they have a weakened immune system, or are already ill.1

Pneumonia can also develop into a serious lung disease that may require treatment in a hospital if it causes complications. Dr. Melissa Conrad Stppler on MedicineNet says that treatment for pneumonia may be necessary to control the spread of viral or bacterial infections in the body....

00:22

Tumor necrosis factor alpha (TNF-) reduces intestinal vitamin C uptake. "IndyWatch Feed Health"

PMID:  Am J Physiol Gastrointest Liver Physiol. 2018 Apr 6. Epub 2018 Apr 6. PMID: 29631379 Abstract Title:  Tumor Necrosis Factor alpha (TNF-) reduces intestinal vitamin C uptake: a role for NF-B mediated signaling. Abstract:  Sodium-dependent vitamin C transporter-1 (SVCT-1) is the major transporter mediating intestinal vitamin C uptake. Intestinal inflammation and prolonged infection are associated with an increased serum and intestinal mucosa levels of TNF-, which also exerts profound effects on intestinal absorption process. Elevated levels of TNF- have been linked to the pathogenesis of IBD and malabsorption of nutrients and these patients have low levels of vitamin C. To date, little is known about the effect of TNF- on intestinal absorptionof vitamin C. We studied the impact of TNF- on ascorbic acid (AA) transport using variety of intestinal preparations. The expression level of hSVCT-1 mRNA is significantly lower in IBD patients. TNF- treated Caco-2 cells and mice showed a significant inhibition of intestinalC-AA uptake. This inhibition was associated with significant decreases in SVCT-1 protein, mRNA and hnRNA levels in TNF- treated Caco-2 cells, mouse jejunum, and enteroids. Also, TNF- caused a significant inhibition in the SLC23A1 promoter activity. Furthermore, treatment of Caco-2 cells with celastrol (NF-B inhibitor) blocked the inhibitory effect caused by TNF- on AA uptake, SVCT-1 protein and mRNA expression, as well as the activity of SLC23A1 promoter. Treatment of TNF- also led to a significant decrease in the expression of HNF1, which drives the basal activity of SLC23A1 promoter and this effect was reversed by celastrol. Together, these findings show that TNF- inhibits intestinal AA uptakeand this effect is mediated, at least in part, at the level of transcription of the SLC23A1 gene via the NF-B pathway.

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00:12

Sesamin can potentially be employed as an effective adjuvant therapeutic agent in ameliorating tumor development and progression. "IndyWatch Feed Health"

PMID:  Eur J Pharmacol. 2017 Nov 15 ;815:512-521. Epub 2017 Oct 12. PMID: 29032105 Abstract Title:  A comprehensive review on the anti-cancer properties and mechanisms of action of sesamin, a lignan in sesame seeds (Sesamum indicum). Abstract:  Sesamin is the major active ingredient is Sesamum indicum seeds. Several studies revealed that sesamin possesses potent anti-cancer properties. The anti-cancer effects of sesamin have been mainly attributed to its anti-proliferative, pro-apoptotic, anti-inflammatory, anti-metastatic, anti- and pro-angiogenic, and pro-autophagocytic activities. In this review, we provide a comprehensive summary of the reported anti-cancer effects of sesamin, both in vitro and in vivo. Experimental findings related to the potential of sesamin to attenuate oxidative stress, inflammation, proliferation, metastasis, and angiogenesis in various cancer cells and tumors are analyzed. Studies focusing on the ability of sesamin to induce apoptosis and autophagy in cancer cells are also underscored. Moreover, the molecular mechanisms underlying the anti-cancer effects of sesamin are highlighted, and the major signaling pathways targeted by sesamin are identified. Although the exact signaling events triggered by sesamin in cancer cells are not fully revealed, our analysis indicates that NF-B, STAT3, JNK, ERK1/2, p38 MAPK, PI3K/AKT, caspase-3, and p53 signaling pathways are critically involved in mediating the anti-cancer effects of sesamin. In sum, the experimental evidence suggesting that sesamin could exert potent anti-cancer activities in vitro and in vivo is compelling. Hence, sesamin can potentially be employed as an effective adjuvant therapeutic agent in ameliorating tumor development and progression, and therefore, it could be used in the prevention and/or treatment of various types of cancer.

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Wednesday, 11 April

23:52

Sesamin improves cardiac function and prevents the development of cardiac hypertrophy. "IndyWatch Feed Health"

PMID:  Cell Physiol Biochem. 2017 ;44(6):2212-2227. Epub 2017 Dec 13. PMID: 29248930 Abstract Title:  Sesamin Protects Against Cardiac Remodeling Via Sirt3/ROS Pathway. Abstract:  BACKGROUND/AIMS: Cardiac remodeling is associated with oxidative stress. Sesamin, a well-known antioxidant from sesamin seeds, have been used extensively as traditional health foods. However, there is little known about the effect of sesamin on cardiac remodeling. Therefore, the present study aimed to determine whether sesamin could protect against cardiac remodeling and to clarify potential molecular mechanisms.METHODS: The mice were subjected to either transverse aortic constriction (TAC) or sham surgery (control group). Beginning one week after surgery, the mice were oral gavage treated with sesamin (100mgkg-1day-1) or vehicle for 3 weeks. Cardiac hypertrophy was assessed by echocardiographic parameters, histological analyses and hypertrophic markers.RESULTS: Sesamin alleviated cardiac hypertrophy, inhibited fibrosis and attenuated the inflammatory response. The increased production of reactive oxygen species, the activation of ERK1/2-dependent nuclear factor-B and the increased level of Smad2 phosphorylation were observed in cardiac remolding model that were treated with sesamin. Furthermore, TAC induced alteration of Sirt3 and SOD2 was normalized by sesamin treatment. Finally, a selective Sirt3 inhibitor 3-TYP blocks all the protective role of sesamin, suggesting that a Sirt3-dependent effect of sesamin on cardiac remodeling.CONCLUSION: Sesamin improves cardiac function and prevents the development of cardiac hypertrophy via Sirt3/ROS pathway. Our results suggest the protective effect of sesamin on cardiac remolding.

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23:40

Sesamin inhibits the proliferation and migration of cervical cancer cells. "IndyWatch Feed Health"

PMID:  Life Sci. 2018 May 1 ;200:87-93. Epub 2018 Mar 2. PMID: 29505783 Abstract Title:  Sesamin induces ER stress-mediated apoptosis and activates autophagy in cervical cancer cells. Abstract:  AIMS: Sesamin, a major lignan of sesame oil, has demonstrated anticancer properties. However, its anticancer effects on cervical cancer have not been studied. Here, we investigated the effects of sesamin on cervical cancer (HeLa) cell line and explored the underlying mechanisms.MAIN METHODS: HeLa cells were cultured with sesamin. CCK-8 and scratch wound test were applied to detect the proliferation and migration ability, while flow cytometry and TUNEL staining were applied to detect apoptosis. The expression of Bax and Bcl-2 was assessed by Western blotting. Further observe the ultrastructure using transmission electron microscopy (TEM) and detect the expression of caspase-12, GRP78, GADD153, IRE1, p-IRE1, JNK, p-JNK, LC3I/II and beclin-1. In addition, HeLa cells were treated with 3-MA (an autophagy inhibitor) and/or sesamin. Then detect the expression of LC3I/II and cell viability.KEY FINDINGS: CCK-8 and scratch wound test revealed that sesamin inhibits HeLa cells proliferation and migration, while flow cytometry and TUNEL staining indicated that sesamin induces apoptosis in these cells. In sesamin group, the expression of Bax, caspase-12, GRP78, GADD153, p-IRE1, p-JNK, LC3I/II and beclin-1 was up-regulated while Bcl-2 was down-regulated compared to control group. Further research revealed that sesamin also induces Hela cells autophagy and inhibition of autophagy increases cell viability of sesamin-treated HeLa cells.SIGNIFICANCE: Sesamin inhibits proliferation/migration of HeLa cells and induces ER stress-mediated apoptosis through IRE1/JNK pathway, and that it activates autophagy and autophagic death in these cells, further validate the anticancer effect of sesamin.

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23:00

Sesamol reduces total oxidant status, malondialdehyde levels and inhibits cataract formation. "IndyWatch Feed Health"

PMID:  Turk J Ophthalmol. 2017 Dec ;47(6):309-314. Epub 2017 Dec 27. PMID: 29326846 Abstract Title:  The Protective Effect of Sesamol in the Selenite-induced Experimental Cataract Model. Abstract:  Objectives: To investigate the potential protective effects of sesamol in an experimental cataract model.Materials and Methods: Twenty-one Spraque Dawley rat pups were randomly assigned into three groups, seven rats in each. All the rats except for those in the control group were injected subcutaneously with a single dose of sodium selenite on postpartum day 9. On days 10-14, rats in the sham group were intraperitoneally administered 50 mg/kg/day saline solution, while rats in the sesamol group were given 50 mg/kg/day sesamol by the same route. Following cataract grading, the lenses and capsules were extracted and the mean levels of reduced glutathione (GSH), malondialdehyde (MDA), total antioxidant status (TAS) and total oxidant status (TOS) in lens supernatants were biochemically analyzed.Results: The control group did not show any development of cataract. It was found that the mean cataract grade in the sesamol group was significantly lower than that of the sham group (p

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22:46

World Health Organization Moving Towards Recommending Cannabis for Medical Purposes "IndyWatch Feed Health"

close up of an oil made from the essential oil of the cannabis hemp plant with buds next and around the syringe

by Paul Fassa
Health Impact News

In late December 2017, the WHO (World Health Organization) issued a statement from its Expert Committee on Drug Dependence (ECDD):

The ECDD did an initial review of a cannabis compound called cannabidiol (CBD). Recent evidence from animal and human studies shows that its use could have some therapeutic benefit for seizures due to epilepsy and related conditions.

Current evidence also shows that cannabidiol is not likely to be abused or create dependence, such as for other cannabinoids (such as Tetra Hydro Cannabinol (THC), for instance).

The ECDD, therefore, concluded that current information does not justify scheduling of cannabidiol and postponed a fuller review of cannabidiol preparations to May 2018, when the committee will undertake a comprehensive review of cannabis and cannabis-related substances. [Emphasis added] (Source)

The WHO is responsible for setting health policies throughout the world, as its name indicates. The WHO is part of the United Nations, with the function of creating international policies regarding medical practices and setting drug standards and classifications or schedules with the expectation that individual nations within the UN comply.

Raul Elizalde, a medical marijuana advocate and president of hemp-CBD company HempMeds Mexico, personally lobbied the WHOs ECDD a few days before that committee met. Elizalde helped spearhead Mexicos medical cannabis legalization in June of 2017. His personal conviction goes beyond profiting from the Mexican CBD company hes created.

His first daughter was having hundreds of seizures weekly until CBD with less than one percent THC was introduced to her. Now shes off the pharmaceutical medications and experiencing only a very few occasional less severe seizures.

Elizalde confirmed the already known medical efficacy and safe...

22:37

Arctigenin from F. Arctii could contribute to prevention of inflammatory, allergic, and infectious diseases. "IndyWatch Feed Health"

PMID:  Evid Based Complement Alternat Med. 2015 ;2015:368105. Epub 2015 Oct 13. PMID: 26550018 Abstract Title:  Arctigenin from Fructus Arctii (Seed of Burdock) Reinforces Intestinal Barrier Function in Caco-2 Cell Monolayers. Abstract:  Fructus Arctii is used as a traditional herbal medicine to treat inflammatory diseases in oriental countries. This study aimed to investigate effect of F. Arctii extract on intestinal barrier function in human intestinal epithelial Caco-2 cells and to reveal the active component of F. Arctii. We measured transepithelial electrical resistance (TEER) value (as an index of barrier function) and ovalbumin (OVA) permeation (as an index of permeability) to observe the changes of intestinal barrier function. The treatment of F. Arctii increased TEER value and decreased OVA influx on Caco-2 cell monolayers. Furthermore, we found that arctigenin as an active component of F. Arctii increased TEER value and reduced permeability of OVA from apical to the basolateral side but not arctiin. In the present study, we revealed that F. Arctii could enhance intestinal barrier function, and its active component was an arctigenin on the functionality. We expect that the arctigenin from F. Arctii could contribute to prevention of inflammatory, allergic, and infectious diseases by reinforcing intestinal barrier function.

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22:30

6 Things That Happen to Your Body If You Walk Every Day "IndyWatch Feed Health"

According to recent survey results, its estimated that around 80 percent of Americans (and those living in the U.K. too) between the ages of 25 and 64 dont work out enough each week to meet the recommended levels of government-specified daily physical activity. (1) While fitness is definitely on the rise and more people are doing some... View Article

The post 6 Things That Happen to Your Body If You Walk Every Day appeared first on Healthy Holistic Living.

22:18

Florida Mom Seeks 2nd Opinion on Dying Newborn After Car Accident Loses Custody of All Three Children and Baby Dies in State Care "IndyWatch Feed Health"

Johnna Furman baby Gabriel

Baby Gabriel. Photo from Facebook.

by Health Impact News/MedicalKidnap.com Staff

When an 8 month pregnant mother arrived at the hospital after a car accident, her baby was clearly in trouble. Doctors allegedly seemed to be more concerned about Johnna Furmans broken wrist than the emergency facing her unborn baby. Her baby needed to be born quickly, but the delay of a necessary c-section resulted in life threatening lack of oxygen to the baby in the womb.

Baby Gabriel was born with brain damage and other serious medical conditions allegedly arising from this lack of oxygen.

Throughout his first week and a half of life, doctors at the University of Florida Shands Hospital told Johnna that her baby would not survive.

She refused to accept that answer.

When she tried to transfer care of her baby to a local childrens hospital for a second opinion, doctors from Shands Hospital reported her to Child Protective Services.

While doctors blamed the mother, Johnna says that it was their medical malpractice that resulted in brain damage to her baby, ultimately leading to his death, and that the hospital is covering up what they did by blaming her.

Child Protective Services seized her baby and her other 2 children 11 days after the car accident.

Due to some legal gymnastics, evidence that would have proven her innocence was not heard by the judge and her parental rights were terminated less than a year later. She had another baby the following year, but Florida seized custody of that baby, too, because of a law that was changed a month after the baby was born and applied to her retroactively.

In a video that Johnna recorded to talk about her case, she said:

My familys gone. I can never have another child.

I dont understand how this is supposed to be the American dream, that justice doesnt matter. The truth doesnt matter.

Delayed C-section Results in Brain Damage

Johnna Furmans nightmare beg...

21:59

This study demonstrates that Arctii Fructus inhibits the proliferation and metastatic properties of colorectal cancer cells "IndyWatch Feed Health"

PMID:  Am J Chin Med. 2017 ;45(6):1309-1325. Epub 2017 Aug 22. PMID: 28830210 Abstract Title:  Arctii Fructus Inhibits Colorectal Cancer Cell Proliferation and MMPs Mediated Invasion via AMPK. Abstract:  Although Arctii Fructus (AF) has been shown to have various pharmacological effects, there have been no studies concerning the inhibitory effects of AF on the metastatic properties of colorectal cancer (CRC). The aim of this study was to investigate whether AF could suppress CRC progression by inhibiting cell growth, epithelial-mesenchymal transition (EMT), migration, and the invasion ability of CRC cells. AF decreased proliferation of CRC cells by inducing cell cycle arrest and apoptosis via extrinsic and intrinsic apoptotic pathways. Regarding metastatic properties, AF inhibited EMT by increasing the expression of the epithelial marker, E-cadherin, and decreasing the expression of the mesenchymal marker, N-cadherin, in CT26 cells. Moreover, AF decreased the migration and invasion of CT26 cells by inhibiting matrix metalloproteinase-2 (MMP-2) and MMP-9 activity. We confirmed that the decreased invasion ability and MMP-9 activity by AF treatment involved AMP-activated protein kinase (AMPK) activation. Collectively, this study demonstrates that AF inhibits the proliferation and metastatic properties of CRC cells.

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21:43

Treatment with A. lappa resulted in body weight decrease and blood glucose suppression. "IndyWatch Feed Health"

PMID:  Lab Anim Res. 2017 Sep ;33(3):251-255. Epub 2017 Sep 27. PMID: 29046701 Abstract Title:  Safety of 8-weeks oral administration ofL. Abstract:  Recently, worldwide dietary reference intakes have been considered an important guideline for public health. Some governments and the World Health Organization (WHO) provide guidelines concerning dietary intake. Although an ingredient may have a history of use as a culinary material, changes in the environment over time suggest that the acceptable maximum intake each of food/culinary material should be regularly evaluated.L. has been used as a culinary material for many centuries in Korea and Japan and some recent studies have reported related therapeutic effects. However, there are no reports on the safety of repeated oral administration. In this study, we evaluated the safety of a 8-weeks repeated oral intake of. We concluded that treatment with

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21:19

FDA Censorship Could Impact Preterm Births "IndyWatch Feed Health"

Dont let FDA stifle free speech and suppress the scientific evidence that vitamin D helps prevent preterm births. Action Alert!

As we reported recently, Ocean Sprays petition for a qualified health claim for cranberry products and reduced risk of urinary tract infections demonstrates the horrible track record FDA has in allowing free speech about the benefits of foods and supplements. The agency now has a chance to approve a health claim for vitamin D in reducing the risk of preterm births. Will the agency allow this information to be communicated to consumers, potentially saving thousands of lives, or will it once again protect drug industry monopolies by stifling free speech about cheap, safe, and effective food and supplements?

The role of vitamin D in preventing preterm births is well established scientifically. Recently, the Medical University of South Carolina, in partnership with GrassrootsHealth, found that pregnant women who maintain vitamin D levels of 40-60 ng/ml experience a 60% reduction of preterm birth risk, with zero safety issues.

This information could alleviate a lot of suffering. In 2016, one in ten babies were born prematurely in the US, costing $12.7 billion annually and creating an increased risk of death, breathing and intestinal issues in the short-term, and potentially leading to long-term developmental delays. Vitamin D is an inexpensive and safe preventative method. To us, this seems like a no-brainer, but the FDA has fought tooth and nail against many legitimate health claims for food and food supplements. In our article last week on the qualified health claim for cranberries, we mentioned that currently approved claims for supplements have largely been the result of court victories over the FDA.

Our friends at the Organic & Natural Health Association (ONHA) have petitioned the FDA to allow a health claim for vitamin D describing its role in reducing preterm births. We hope the FDA will let the science speak for itself and grant ONHAs petitionbut we must hold the agencys feet to the fire.

...

21:18

The Aluminum Autism Link "IndyWatch Feed Health"

A new study shows newborns are injected with 17 times the allowable level of aluminum.  Action Alert!

The peer-reviewed study demonstrates that aluminum doses in vaccines are based on efficacythat is, spurring the bodys immune responserather than safety. This means, according to the researchers, that on their first day of life, infants receive 17 times more aluminum than would be allowed if aluminum doses in vaccines were set according to a babys body weight. The researchers also contend that errors were made in establishing safe levels of aluminum exposure in humans, leading to dangerous levels of aluminum being injected into young children.

Another recent study found that autistic children have up to ten times more aluminum in their brains that what is considered safe in adults.

ANH-USA has been raising the alarm about aluminum in vaccines for a number of years. As the researchers note, safety testing proving aluminum adjuvants to be safe when injected into children has never been conducted. Established safety levels for aluminum exposure that are often referenced are based on ingested aluminum, of which only about 0.25% is absorbed, rather than injected aluminum, where almost all of it is absorbed over timeaccumulating in various organs, including the brain. Animal studies have also demonstrated a link between repeated inoculation with aluminum-containing vaccines and severe neurobehavioral outcomes (restlessness, muscle tremors, loss of response to stimuli), the presence of aluminum in central nervous system tissue, and altered expression of certain genes in the brain.

Given the mounting research showing both the dangers of aluminum exposure and concerns about the safety of injecting young children with multiple aluminum-laden vaccines, it is imperative that parents are afforded the right to choose which vaccines are appropriate for their children. Its also time for the FDA and the CDC to stop relying on mere belief that aluminum adjuvants are safe, and to conduct rigorous safety testing on these vaccines.

Action Alert! Write to the FDA, CDC, and Congress telling them of this new study and...

21:17

Florida Mom Seeks 2nd Opinion on Dying Newborn After Car Accident Loses Custody of All Three Children and Baby Dies in State Care "IndyWatch Feed Health"

Johnna Furman baby Gabriel

Baby Gabriel. Photo from Facebook.

by Health Impact News/MedicalKidnap.com Staff

When an 8 month pregnant mother arrived at the hospital after a car accident, her baby was clearly in trouble. Doctors allegedly seemed to be more concerned about Johnna Furmans broken wrist than the emergency facing her unborn baby. Her baby needed to be born quickly, but the delay of a necessary c-section resulted in life threatening lack of oxygen to the baby in the womb.

Baby Gabriel was born with brain damage and other serious medical conditions allegedly arising from this lack of oxygen.

Throughout his first week and a half of life, doctors at the University of Florida Shands Hospital told Johnna that her baby would not survive.

She refused to accept that answer.

When she tried to transfer care of her baby to a local childrens hospital for a second opinion, doctors from Shands Hospital reported her to Child Protective Services.

While doctors blamed the mother, Johnna says that it was their medical malpractice that resulted in brain damage to her baby, ultimately leading to his death, and that the hospital is covering up what they did by blaming her.

Child Protective Services seized her baby and her other 2 children 11 days after the car accident.

Due to some legal gymnastics, evidence that would have proven her innocence was not heard by the judge and her parental rights were terminated less than a year later. She had another baby the following year, but Florida seized custody of that baby, too, because of a law that was changed a month after the baby was born and applied to her retroactively.

In a video that Johnna recorded to talk about her case, she said:

My familys gone. I can never have another child.

I dont understand how this is supposed to be the American dream, that justice doesnt matter. The truth doesnt matter.

Delayed C-section Results in Brain Damage

Johnna Furmans nightmare began...

20:51

Burdock complex could attenuate H. pylori infection by inhibiting adhesion and subsequent inflammatory response on the gastric epithelial cells. "IndyWatch Feed Health"

PMID:  Helicobacter. 2018 Mar 8. Epub 2018 Mar 8. PMID: 29520881 Abstract Title:  Beneficial effect of Burdock complex on asymptomatic Helicobacter pylori-infected subjects: A randomized, double-blind placebo-controlled clinical trial. Abstract:  BACKGROUND: Burdock complex (BC) constitutes of burdock (Arctium lappa), angelica (Angelica sinensis), gromwell (Lithospermum erythrorhizon), and sesame (Sesamum indicum) oil, which are commonly used in traditional Chinese medicine (TCM) for treating various disorders. This study intended to examine the anti-H. pylori activity of BC on AGS cell model as well as in asymptomatic H. pylori-infected subjects.MATERIALS AND METHODS: AGS cell incubated with H. pylori and treated with BC to evaluate the minimum inhibition concentration (MIC), cell viability (MTT) anti-adhesion activity, and inflammatory markers. In case of clinical trial, H. pylori-positive subjects (urea breath test [UBT]>10%, n = 36) were enrolled and requested to intake BC (n = 19) or placebo (n = 17) for 8 weeks. Antioxidant capacity, total phenol, UBT, inflammatory markers were analyzed at the initial, 4th, 8th, and 10th weeks. Moreover, the endoscopic examination was carried out on baseline and 10th week.RESULTS: In vitro studies showed that BC treatment significantly inhibited (P 

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20:43

Protected: Letter-to-Editor Campaign "IndyWatch Feed Health"

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20:39

Probiotics Detoxify Harmful Chemicals from the Body "IndyWatch Feed Health"

By Alex Pietrowski

The study of gut health and the microbiome is on the cutting edge of wellness, and people are returning to diets that include fermented, probiotic foods. Kombucha is massively popular today, as is kefir, sauerkraut, yogurt and other natural homemade foods, and our understanding of the benefits of probiotics continues to grow.

We are learning how mood may be heavily influenced by gut health, how poor gut health can contribute to depression, and even how the microbiome affects metabolism and obesity.

Furthermore, we are also learning just how vulnerable our natural colony of internal bacteria is to the foods and chemicals we ingest, with glyphosate having a profoundly destructive effect on healthy gut bacteria. And as we learn more, we are also realizing that destroying the bodys bacteria with antibiotics can have long-term negative effects on overall health.

Did you know, though, that probiotics can also have a detoxifying effect on the body, helping us to expel many of the toxins and chemicals we consume on a daily basis?

Sayer Ji of Green Med Info explains seven ways in which probiotics help to detoxify chemicals within the body.

  • ...

20:37

These results demonstrated that arctigenin could inhibit NAFLD progression. "IndyWatch Feed Health"

PMID:  Nutr Res. 2018 Feb 11. Epub 2018 Feb 11. PMID: 29525610 Abstract Title:  Arctigenin protects against steatosis in WRL68 hepatocytes through activation of phosphoinositide 3-kinase/protein kinase B and AMP-activated protein kinase pathways. Abstract:  Arctigenin (ATG), a lignin extracted from Arctium lappa (L.), exerts antioxidant and anti-inflammatory effects. We hypothesized that ATG exerts a protective effect on hepatocytes by preventing nonalcoholic fatty liver disease (NAFLD) progression associated with lipid oxidation-associated lipotoxicity and inflammation. We established an in vitro NAFLD cell model by using normal WRL68 hepatocytes to investigate oleic acid (OA) accumulation and the potential bioactive role of ATG. The results revealed that ATG inhibited OA-induced lipid accumulation, lipid peroxidation, and inflammation in WRL68 hepatocytes, as determined using Oil Red O staining, thiobarbituric acid reactive substance assay, and inflammation antibody array assays. Quantitative RT-PCR analysis demonstrated that ATG significantly mitigated the expression of acetylcoenzyme A carboxylase 1 and sterol regulatory element-binding protein-1 and significantly increased the expression of carnitine palmitoyltransferase 1 and peroxisome proliferator-activated receptor alpha. The 40 targets of the Human Inflammation Antibody Array indicated that ATG significantly inhibited the elevation of the U937 lymphocyte chemoattractant, ICAM-1, IL-1, IL-6, IL-6sR, IL-7, and IL-8. ATG could activate the phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) and AMP-activated protein kinase (AMPK) pathways and could increase the phosphorylation levels of Akt and AMPK to mediate cell survival, lipid metabolism, oxidation stress, and inflammation. Thus, we demonstrated that ATG could inhibit NAFLD progression associated with lipid oxidation-associated lipotoxicity and inflammation, and we provided insights into the underlying mechanisms and revealed potential targets to enable a thorough understanding of NAFLD progression.

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20:18

These results provide evidence of novel anti-inflammatory mechanisms of A. lappa "IndyWatch Feed Health"

PMID:  Evid Based Complement Alternat Med. 2018 ;2018:6346734. Epub 2018 Jan 18. PMID: 29576797 Abstract Title:  Inhibitory Effect and Mechanism ofExtractInflammasome Activation. Abstract:  , Compositae, is considered a potential source of nutrition and is used as a traditional medicine in East Asian countries for centuries. Although several studies have shown its biological activities as an anti-inflammatory agent, there have been no reports onwith regard to regulatory role in inflammasome activation. The purpose of this study was to investigate the inhibitory effects ofextract (ALE) on NLRP3 inflammasome activation and explore the underlying mechanisms. We found that ALE inhibited IL-1secretion from NLRP3 inflammasome activated bone marrow derived macrophages but not that secreted by NLRC4 and AIM2 inflammasomes activation. Mechanistic studies revealed that ALE suppressed the ATPase activity of purified NLRP3 and reduced mitochondrial reactive oxygen species (mROS) generated during NLRP3 activation. Therefore, the inhibitory effect of ALE on NLRP3 inflammasome might be attributed to its ability to inhibit the NLRP3 ATPase function and attenuated the mROS during inflammasome activation. In addition, ALE significantly reduced the LPS-induced increase of plasma IL-1in mouse peritonitis model. These results provide evidence of novel anti-inflammatory mechanisms of, which might be used for therapeutic applications in the treatment of NLRP3 inflammasome-associated inflammatory disorders.

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20:14

The Allergy Epidemic in Children Launched in 80s and 90s "IndyWatch Feed Health"

By Heather Fraser

The Epidemic of Allergy in Children Launched in the Late 1980s and Early 1990s

The epidemic of allergy in children was launched in the period between the late 1980s and early 1990s. ER admission records, back-to-back United Kingdom (UK) cohort studies and eyewitness accounts of teachers confronted by the flood of severely allergic children confirm this period of change. This allergy epidemic occurred in specific countries (UK, Australia, Canada, US primarily), involving just children and at the same time. What has the power to do that?

In my book, I traced some of the history of allergy and anaphylaxiswords coined to describe an outcome of having for the first time paired a vaccine with the needle. Thus, doctors became keenly aware of the danger of contaminant proteins in any injected product.

There is ample evidence in the medical literature on the role of vaccination, the toxicity of vaccines and alum adjuvants in creating atopy that one does not need to speculate. Allergists already know.

Using the theory of food oils in the vaccines to explain the sudden nature of epidemic allergy does nothing to forward the conversation. We did not suddenly put food oils, bee venom, latex, dust, pollens, etc. in the vaccines.

Allergy is an evolved defense against acute toxicity and is provoked every time one is vaccinated (generally described as the Th1-Th2 paradigm). One can be sensitized to anything in the body or outside of it throug...

20:13

Dangers of Aluminum: Excerpt from Manufactured Crisis "IndyWatch Feed Health"

Via 

The following is an excerpt from the documentary Manufactured Crisis, a film by Alliance for Natural Health.

It features scientists speaking on the dangers of aluminum on the human body and the obvious ways we are exposed every day.

Of particular concern is vaccination because the aluminum is intramuscularly injected and passes the blood brain barrier.

One of the scientists is Chris Exley, PhD whom weve interviewed before.

 

Watch the full film.


Please help us out by sharing!

This article (Dangers of Aluminum: Excerpt from Manufactured Crisis) appeared at Natural Blaze, via...

19:46

These scientific findings of wound healing activity supports the traditional claims for Wedelia trilobata leaves. "IndyWatch Feed Health"

PMID:  J Ethnopharmacol. 2012 Jun 14 ;141(3):817-24. Epub 2012 Mar 20. PMID: 22465731 Abstract Title:  Evaluation of the wound healing potential of Wedelia trilobata (L.) leaves. Abstract:  ETHNOPHARMACOLOGICAL RELEVANCE: Wedelia trilobata (L.) Hitchc (Asteraceae) leaves are used in the treatment of wounds by traditional healers. Despite the use of this plant in wound healing, there is a scarcity of scientific data to support its therapeutic application.AIM OF THE STUDY: To investigate the wound healing potential of Wedelia trilobata (L.) leaves commonly employed by traditional healers and to clarify its traditional use in a scientific investigation.MATERIALS AND METHODS: An ethanolic extract of Wedelia trilobata leaves was subjected to column chromatography. Hexane, ethyl acetate (WEA) and chloroform:methanol (50:50) (WCM) fractions were obtained. The fractions were tested using relevant in vitro wound healing assays. Antioxidant activity was measured by the DPPH assay. The fibroblast proliferation, oxidative stress using hydrogen peroxide, an in vitro scratch assay, and increasing collagen content was determined using fibroblast L929. Minimum inhibitory concentrations (MICs) were determined against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Pseudomonas aeruginosa.RESULTS: WEA (3g/mL) promoted fibroblast L929 survivability up to more than 90% before and more than 85% after hydrogen peroxide induced oxidative stress. WEA (3 g/mL) induced a 70% migration rate in the in vitro scratch assay and the collagen content was increased to 261 g/mL compared to the control (57.5 g/mL). WCM exhibited a scavenging activity for DPPH with an IC(50) value of 179.5 g/mL comparable to BHT (139.3 g/mL). WEA was active against gram positive bacteria Staphylococcus aureus, Staphylococcus epidermidis with MIC values of 62.5 and 31.25 g/mL, respectively.CONCLUSION: These scientific findings of wound healing activity supports the traditional claims for Wedelia trilobata (L.) leaves. The WEA displayed antibacterial and fibroblast stimulatory activities while WCM exhibited antioxidant to indicate its potential wound healing properties. However further studies to isolate the antibacterial, antioxidant and fibroblast stimulatory compounds that contribute to the wound healing properties of this plant are needed.

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19:46

Childbirth Choices Matter: Why an Elective C-section May Not Be the Best Decision for Mom or Baby "IndyWatch Feed Health"


Originally published on www.focusforhealth.org

It may be shocking to learn that thirty percent of American babies are born via Cesarean delivery (CD). This statistic doesnt mean that one-third of all pregnant women are having complications that lead them to require an emergency cesarean. Many women are opting to have an elective CD

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19:33

Antimicrobial diterpenoids of Wedelia trilobata. "IndyWatch Feed Health"

PMID:  Molecules. 2016 Apr 7 ;21(4):457. Epub 2016 Apr 7. PMID: 27070557 Abstract Title:  Antimicrobial Diterpenoids of Wedelia trilobata (L.) Hitchc. Abstract:  Continued interest in the metabolites of Wedelia trilobata (L.) Hitchc, a notoriously invasive weed in South China, led to the isolation of twenty-six ent-kaurane diterpenoids, including seven new ones 1-7. Their structures and relative configuration were elucidated on the basis of extensive spectroscopic analysis, including 1D- and 2D-NMR experiments. The antimicrobial activities of all isolated diterpenoids were evaluated against a panel of bacteria and fungi.

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18:53

Creeping daisy extract has apoptotic and anti-leukemia activity in MEG-01 cells. "IndyWatch Feed Health"

PMID:  Afr J Tradit Complement Altern Med. 2017 ;14(3):167-174. Epub 2017 Mar 1. PMID: 28480428 Abstract Title:  PURIFICATION AND FRACTIONAL ANALYSIS OF METHANOLIC EXTRACT OFPOSSESSING APOPTOTIC AND ANTI-LEUKEMIC ACTIVITY. Abstract:  BACKGROUND: (.)(WT), commonly known as yellow dots or creeping daisy, is a shrub possessing potent biological activities, and is traditionally used a medicinal plant in Ayurveda, Siddha and Unani systems of medicines, and it has also been tried against leukemia cell line MEG- 01. In the present study, purification and screening of the plant was done for bioactive compounds in methanolic extract of WT for apoptotic and anti-leukemia activity.MATERIALS AND METHODS: The methanolic extract of WT was initially purified through thin layer chromatography (TLC) and screened for the apoptotic and anti-leukemia activities. The positive band of TLC was subjected to silica gel column chromatography for further purification and the fractions obtained from it were screened again for anti-leukemia activity through thymidine uptake assay and apoptotic activity by DNA fragmentation, nuclear staining and flow cytometry assays. The fraction with positive result was subjected to HPLC for analysis of bioactive components.RESULTS: Out of many combinations of solvents, the methanol and dichloromethane combination in the ratio 6:4 has revealed two bands in TLC, among which the second band showed positive results for apoptotic and anti-leukemic activities. Further purification of second band through silica gel chromatography gave five fractions in which the 3fraction gave positive results and it shows single peak during compositional analysis through HPLC.CONCLUSION: The single peak revealed through HPLC indicates the presence of pure compound with apoptotic and anti-leukemia activities encouraging for further structural analysis.

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18:23

The Mediterranean diet was associated with reduced depression risk. "IndyWatch Feed Health"

PMID:  Eur J Nutr. 2018 Mar 7. Epub 2018 Mar 7. PMID: 29516224 Abstract Title:  Does the MIND diet decrease depression risk? A comparison with Mediterranean diet in the SUN cohort. Abstract:  PURPOSE: To prospectively evaluate the association of the Mediterranean-DASH diet intervention for neurodegenerative delay (MIND) diet and the Mediterranean diet (and their components), and depression risk.METHODS: We followed-up (median 10.4 years) 15,980 adults initially free of depression at baseline or in the first 2 years of follow-up. Food consumption was measured at baseline through a validated food-frequency questionnaire, and was used to compute adherence to the MIND and the Mediterranean diets. Relationships between these two diets and incident depression were assessed through Cox regression models.RESULTS: We identified 666 cases of incident depression. Comparing the highest versus the lowest quartiles of adherence, we found no association of the MIND diet and incident depression. This relation was statistically significant for the Mediterranean diet {hazard ratio (HR) 0.75, [95% confidence interval (95% CI) 0.61, 0.94]; p

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18:16

A pecan intervention had a concurrent and clinically significant effect on several relevant markers of cardiometabolic risk. "IndyWatch Feed Health"

PMID:  Nutrients. 2018 Mar 11 ;10(3). Epub 2018 Mar 11. PMID: 29534487 Abstract Title:  A Pecan-Rich Diet Improves Cardiometabolic Risk Factors in Overweight and Obese Adults: A Randomized Controlled Trial. Abstract:  Evidence from observational and intervention studies has shown a high intake of tree nuts is associated with a reduced risk of cardiovascular disease (CVD), mortality from type 2 diabetes (T2DM), and all-cause mortality. However, there is limited data regarding their effects on indicators of cardiometabolic risk other than hypercholesterolemia, and little is known about the demonstrable health benefits of pecans ((Wangenh.) K.Koch). We conducted a randomized, controlled feeding trial to compare the effects of a pecan-rich diet with an isocaloric control diet similar in total fat and fiber content, but absent nuts, on biomarkers related to CVD and T2DM risk in healthy middle-aged and older adults who are overweight or obese with central adiposity. After 4 weeks on a pecan-rich diet, changes in serum insulin, insulin resistance (HOMA-IR) and beta cell function (HOMA-) were significantly greater than after the control diet (

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18:03

The consumption of tree nuts has been scientifically proven to improve lifespan and healthspan and should be a part of a healthy diet in the elderly. "IndyWatch Feed Health"

PMID:  Food Funct. 2018 Apr 4. Epub 2018 Apr 4. PMID: 29616249 Abstract Title:  Anti-aging potential of tree nuts with a focus on the phytochemical composition, molecular mechanisms and thermal stability of major bioactive compounds. Abstract:  Tree nuts, complete functional foods, contain macro- and micronutrients of high biological value. These bioactive compounds have a synergistic effect in preventing and delaying many age-related pathologies (e.g. cardiovascular diseases, stroke, type 2 diabetes mellitus, certain types of cancer, and several neurodegenerative diseases). Tree nuts are low in carbohydrates, but they abound in healthy fatty acids, in optimal proportion for a good plasma lipid profile, and are a good source of proteins, rich in proteinogenic amino acids. They contain significant amounts of vitamin E, minerals, polyphenols, and phytosterols. Polyphenols, which are powerful phytochemicals, act as direct and indirect antioxidants, reduce the inflammatory response, improve proteostasis and mitochondrial biogenesis, modulate many cell signaling pathways, have a major role in cytoprotection, are Nrf2/ARE activators, down-regulate the NFB system, promote anticancer potential, and prevent cell senescence. Some of them have senolytic effects, interfere in specific cell signaling pathways modulated by caloric restriction, and protect against UV radiation and photoaging. Moreover, tree nuts are good prebiotics and improve gut microbiota. The stability of polyphenolic compounds and their antioxidant activity can be influenced by cooking techniques, temperature of storage, and post-harvest processing methods. The consumption of tree nuts has been scientifically proven to improve lifespan and healthspan and should be a part of a healthy diet in the elderly.

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17:56

Increased nut consumption was associated with a decreased risk of esophageal squamous cell carcinoma and gastric non-cardia adenocarcinoma. "IndyWatch Feed Health"

PMID:  Gastric Cancer. 2018 Mar 28. Epub 2018 Mar 28. PMID: 29594821 Abstract Title:  Tree nut, peanut, and peanut butter consumption and the risk of gastric and esophageal cancer subtypes: the Netherlands Cohort Study. Abstract:  BACKGROUND: Nut consumption has been associated with reduced cancer-related mortality. However, it is unclear whether nut consumption also reduces the risk of esophageal and gastric cancer subtypes. We prospectively investigated the relationship of tree nut, peanut, and peanut butter intake with risk of esophageal squamous cell carcinoma (ESCC), esophageal adenocarcinoma (EAC), gastric cardia adenocarcinoma (GCA), and gastric non-cardia adenocarcinoma (GNCA) in the Netherlands Cohort Study.METHODS: In 1986, 120,852 males and females, aged 55-69 years, completed a baseline questionnaire on diet and cancer risk factors. After 20.3 years of follow-up, 133 ESCC, 200 EAC, 191 GCA, and 586 GNCA cases, and 3,720 subcohort members were available for multivariable Cox regression analyses, using a case-cohort approach.RESULTS: Increased total nut consumption was significantly associated with a decreased risk of ESCC and GNCA [HRs (95% CIs) for 10+g/day vs. nonconsumers=0.54 (0.30-0.96) and 0.73 (0.55-0.97), respectively], but not with EAC and GCA risk. Similar trends were observed for tree nut and peanut intake, which were mostly nonsignificant. For peanut butter intake, no significant associations were found. When excluding thefirst four years of follow-up to reduce the possible influence of reversed causation, the relation between nut consumption and ESCC risk attenuated, but remained inverse.CONCLUSIONS: Our findings suggest that increased tree nut and peanut consumption is inversely associated with GNCA risk and possibly with ESCC risk, but not with the risk of the other esophageal and gastric cancer subtypes.

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17:50

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17:47

References "IndyWatch Feed Health"

DRAFT WILL ADD MORE

Fluoride and IQ: The 52 Studies

Brain: 52 IQ Studies

Brain: 122 Human Studies

Brain: 220 Animal Studies

Fetal brain

Dong Z, Wan C, Liu J. 1993. Determination of the contents of amino-acid and monoamine neurotransmitters in fetal brains from a fluorosis-endemic area. Journal of Guiyang Medical College 18(4):241-45. (Translated from Chinese into English by the Fluoride Action Network in 2012.)

Du L, Wan C, Cao X, Liu J. 2008. The effect of fluorine on the developing human brain. Fluoride 41(4):327330. (Originally published in Chinese in the Chinese Journal of Pathology 1992;21(4):218-20. Translated from Chinese into English by the Fluoride Action Network.)

He H, Cheng Z, Liu W. 2008. Effects of fluorine on the human fetus. Fluoride 41(4):321326. (Originally published in Chinese in the Chinese Journal of Control of Endemic Diseases 1989;4(3):136-138.Translated by the Fluoride Action Network.)

Yu Y, Wang W, Dong Z, et al. 2008. Neurotransmitter and receptor changes in the brains of fetuses from areas of endemic fluorosis. Fluoride 41(2):134138. (Originally published in Chinese in the Chinese Journal of Endemiology 1996;15:257-259.)

All other references:

Grandjean P, Landrigan PJ. 2014. Neurobehavioral effects of developmental toxicity. Lancet Neurology 13(3):330-38

NRC (National Research Council of the National Academies. 2006. Fluoride in drinking water: a scientific review of EPAs standards. The National Academies Press, Washington D.C....

17:45

Protected: IQ Loss: Economic cost to society "IndyWatch Feed Health"

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17:40

Child psychiatrists research was suspended indefinitely following probe "IndyWatch Feed Health"

The University of Illinois at Chicago (UIC) permanently suspended all research activities for a child psychiatrist years ago following an inquiry into her work, Retraction Watch has learned. In 2015, a UIC spokesperson told us the university had suspended Mani Pavuluris clinical research in 2013, after a child in one of her studies had been Continue reading Child psychiatrists research was suspended indefinitely following probe

17:22

Amaranth Breakfast Porridge "IndyWatch Feed Health"

amaranth porridge, amaranth recipesAmaranth is an ancient gluten free seed (pseudo-grain) that is growing immensely in popularity. The trouble is, most folks who want to eat it have no idea how to prepare it.

The seeds are too tiny for most grain grinders, which leaves the whole grain itself as the most practical way to get started using it in the kitchen. 

The post Amaranth Breakfast Porridge appeared first on The Healthy Home Economist.

17:08

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16:59

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16:28

A higher consumption of processed meat was associated with a higher risk of impairment in agility and lower-extremity function "IndyWatch Feed Health"

PMID:  BMC Med. 2018 Apr 5 ;16(1):50. Epub 2018 Apr 5. PMID: 29622014 Abstract Title:  Consumption of meat in relation to physical functioning in the Seniors-ENRICA cohort. Abstract:  BACKGROUND: Meat is an important source of high-quality protein and vitamin B but also has a relatively high content of saturated and trans fatty acids. Although protein and vitamin B intake seems to protect people from functional limitations, little is known about the effect of habitual meat consumption on physical function. The objective of this study was to examine the prospective association between the intake of meat (processed meat, red meat, and poultry) and physical function impairment in older adults.METHODS: Data were collected for 2982 participants in the Seniors-ENRICA cohort, who were aged60 years and free of physical function impairment. In 2008-2010, their habitual diet was assessed through a validated computer-assisted face-to-face diet history. Study participants were followed up through 2015 to assess self-reported incident impairment in agility, mobility, and performance-based lower-extremity function.RESULTS: Over a median follow-up of 5.2 years, we identified 625 participants with impaired agility, 455 with impaired mobility, and 446 with impaired lower-extremity function. After adjustment for potential confounders, processed meat intake was associated with a higher risk of impaired agility (hazard ratio [HR] for highest vs. lowest tertile: 1.33; 95% confidence interval [CI]: 1.08-1.64; p trend = 0.01) and of impaired lower-extremity function (HR for highest vs. lowest tertile: 1.31; 95% CI: 1.02-1.68; p trend = 0.04). No significant associations were found for red meat and poultry. Replacing one serving per day of processed meat with one serving per day of red meat, poultry, or with other important protein sources (fish, legumes, dairy, and nuts) was associated with lower risk of impaired agility and lower-extremity function.CONCLUSIONS: A higher consumption of processed meat was associated with a higher risk of impairment in agility and lower-extremity function. Replacing processed meat by other protein sources may slow the decline in physical functioning in older adults.

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16:16

600 Students Get Vaccine School Suspension Notices For Non-Compliance "IndyWatch Feed Health"

Roughly 600 students from a Kawartha Lakes, Ontario, Canada school have been suspended for failing to meet vaccine requirements. There are three district health divisions sending out the notices: Haliburton, Kawartha, Pine Ridge. The regions where...

The post 600 Students Get Vaccine School Suspension Notices For Non-Compliance appeared first on Vaxxter.

16:11

Taro flour increases testosterone levels and gametogenic epithelium of Wistar rats. "IndyWatch Feed Health"

PMID:  J Dev Orig Health Dis. 2018 Mar 21:1-4. Epub 2018 Mar 21. PMID: 29559019 Abstract Title:  Taro flour (Colocasia esculenta) increases testosterone levels and gametogenic epithelium of Wistar rats. Abstract:  This study evaluated the effects of diet containing taro flour on hormone levels and the seminiferous tubules morphology of rats. After weaning, the male rats were divided into two groups (n=12 each): control group (CG) treated with control diet and taro group (TG), fed with 25% taro flour for 90 days. Food, caloric intake, mass and body length were evaluated at experiment end. Testis followed the standard histological processing. Immunostaining was performed using an anti-vimentin antibody to identify Sertoli cells. In histomorphometry, total diameter, total area, epithelial height, luminal height and luminal area were analyzed. The testosterone levels were performed using the radioimmunoassay method. Group TG presented (P

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15:28

Star fruit extracts exhibited a potent hepatic steatosis relieving effect partly by inhibiting the signal transduction of hepatic lipogenesis. "IndyWatch Feed Health"

PMID:  Food Funct. 2017 Dec 13 ;8(12):4496-4507. PMID: 29090700 Abstract Title:  Averrhoa carambola free phenolic extract ameliorates nonalcoholic hepatic steatosis by modulating mircoRNA-34a, mircoRNA-33 and AMPK pathways in leptin receptor-deficient db/db mice. Abstract:  The objective of the present study is to investigate the hepatic steatosis relieving effect of Averrhoa carambola free phenolic extract (ACF) on leptin receptor-deficient (db/db) mice and elucidate the modulation hepatic lipogenesis mechanisms. The serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) assays, accompanying hematoxylin and eosin (H&E) staining, were applied to identify the alleviation of liver histopathological changes. Serum and hepatic lipid assays, combined with oil red O staining, were used to investigate the amelioration of lipid accumulation. Further assessments by quantitative real-time PCR and western blot assays were used to elucidate the suppression of the fatty acid and triglyceride (TG) synthesis mechanisms underlying ACF protection. These results indicated that ACF treatment significantly reduced the liver TG of db/db mice (p

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14:25

Fluoride levels in Longburn water supply "IndyWatch Feed Health"

Palmerston North City Council (PNCC) and Public Health Services of MidCentral Health (PHS) advise of a recent incident relating to the fluoride dosing system at Longburn.

During routine monitoring at 1pm, Tuesday 3 April, elevated fluoride levels were detected in the Longburn community water supply.

Laboratory testing confirmed the elevated levels at 8.7 mg/L, which is above the target level of 0.7 1.0 mg/L.

On notification, the dosing system was immediately switched off. Samples were taken, followed by a complete flushing of the entire Longburn network.

An investigation has identified that the incorrect dosing had started on Thursday 29 March following an unauthorised change made by a contractor, and continued over the Easter holiday period. There are not expected to be any health issues related to the incident.

By 5pm on Tuesday 3 April, fluoride levels in the water supply had dropped to 0.2 mg/L. Samples on 28 March and 4 April tested by a certified laboratory show the fluoride level to be well-within the target level.

We consider this a serious matter and having confirmed the cause of the error, we have taken steps to ensure this doesnt happen again, says Robert Van Bentum, PNCC Water and Waste Services Manager.

Health Impacts

MidCentral Public Health Services advises the levels found in the water supply were well below any short-term exposure guidelines, therefore no acute health effects would be expected from this incident. There is also expected to be no risk of any long-term impacts given the very short period of exposure.

Dr Rob Weir, Medical Officer of Health said: In view of the very short duration of the incident, MidCentral Public Health Services also considers there is an extremely low risk of any cumulative effects from the elevated fluoride levels.

If anyone is concerned about their health, they are advised to see their GP or ring Healthline on 0800 611 116.

*Original article online at http://www.scoop.co.nz/stories/AK1804/S00230/fluoride-levels-in-longburn-water-supply.htm

14:00

An author was accused of faking peer reviews. Turns out he also falsified two images. "IndyWatch Feed Health"

In 2015, the journal Cureus published two neurosurgery papers from the same corresponding author, one month apart. Soon after, the journal uncovered potential irregularities with two reviews during a routine editorial audit, editor John R. Adler Jr. told Retraction Watch: Two faked reviewer accounts (co-opting the names of well known neurosurgeons) seemed to have been Continue reading An author was accused of faking peer reviews. Turns out he also falsified two images.

11:41

FluMist, HPV Vaccine, and State School Boards: All Politics is Local "IndyWatch Feed Health"

By Joshua Mazer In October 2016, my then 11 year old daughter came home with a notice that FluMist- a live attenuated inhalable vaccine containing four strains of live influenza virus- would be distributed in her school. I took my...

07:00

Shocking Statistics Reveal 4 in 10 American Adults Are Now Obese "IndyWatch Feed Health"

By Dr. Mercola

While hard to believe, the most recent statistics1 indicate Americans just keep getting fatter. As of 2015, nearly 40 percent of adults, over 18 percent of teens and nearly 14 percent of young children were obese, not just overweight. Severe obesity has also increased, now affecting nearly 8 percent of adults; a 2.3 percent increase since 2007/2008. As reported by the authors:

"Among adults aged 20 years and older, obesity was defined as a body mass index (BMI ) of 30 or more and severe obesity was defined as a BMI of 40 or more Among youth, obesity prevalence was 16.8 percent in 2007-2008 and 18.5 percent in 2015-2016 Obesity prevalence among children aged 2 to 5 years showed a quadratic trend, decreasing from 10.1 percent in 2007-2008 to 8.4 percent in 2011-2012 and then increasing to 13.9 percent in 2015-2016 "

Public Health Messaging Is Not Working

According to The New York Times,2 public health experts have expressed alarm by the rise in obesity despite education efforts. The NYT also added:

"The latest data from the National Health and Nutrition Examination Survey comes at a time when the food industry is pushing back against stronger public health measures aimed at combating obesity. In recent NAFTA negotiations, the Trump administration has proposed rules favored by major food companies that would limit the ability of the United States, Mexico and Canada to require prominent labels on packaged foods warning about the health risks of foods high in sugar and fat."

Indeed, U.K. pediatricians are now warning that the nation's trade deal with the U.S. "could lead to even higher rates of obesity through the import of American foods high in fat and sugar,"3 and that America's hostile stance toward countries with stricter food rules4 to support healthier eating habits threatens the U.K.'s anti-obesity efforts. Professor Russell Viner, president of the Royal College of Pediatrics and Child Health told The Guardian:5...

Avoiding the Top Freak Accidents "IndyWatch Feed Health"

By Dr. Mercola

Motor vehicle accidents once held the top spot for accidental deaths in the U.S., but in 2016 more Americans died from accidental drug overdoses than from car accidents.1 Car accidents aren't the only accidents taking lives. According to the U.S. Centers for Disease Control and Prevention (CDC), there were 146,000 unintentional deaths due to injury. More than 33,000 fell to their death in 2014.2

The CDC ranked unintentional poisonings as the highest number of unintentional injury deaths in 2015, followed closely by falls and over 6,000 individuals who died in an unspecified accident.3 Many of these unspecified accidental deaths fall into a category of freak accidents, some of which can occur in your own backyard.

Accidental Death and Injury Rates Are Rising

The rates of accidental deaths, not including overdoses, appear to be rising each year. In a report from the National Safety Council (NSC), more than 136,000 Americans died accidentally in 2014.4 This number rose to just over 161,000 in 2016, or 18 deaths every hour.5 This NSC video is a short demonstration of the numbers of people who experience accidents and injuries at home, work, in public or in their cars. As Ken Kolosh, the National Safety Council statistical manager, points out,6 Every accident is preventable.

Although many believe murder is a big risk in America, there are nearly eight accidental deaths for every homicide. Previously accidents ranked as low as the seventh leading killer of Americans, but a combination of slowly reducing and preventing illnesses and rising rates of overdoses has raised the rank of accidental deaths to the third leading killer, beating out stroke, Alzheimer's,...

Ditch Your Rubber Ducky "IndyWatch Feed Health"

By Dr. Mercola

Little, yellow rubber ducks often adorn toddler bath time and were popularized when Sesame Street released their classic ode to the duck in February 1970.1 Sung by Sesame Street character Ernie, with the voice of Jim Henderson, the song became a surprise mainstream hit, reaching No.16 on the Billboard Hot 100 in September of the same year and nearly winning a Grammy the following year.

The rise in popularity of the little yellow duck could not have been predicted. In the ensuing years, these little plasticized toys became a staple in toddler bath-time and have gone on to be used in a benefit for the Special Olympics in Illinois when 60,000 of the tiny toys were released into the Chicago River.2

The first rubber toys appeared in the late 1800s5 and were cast solid, intended as chew toys. By the 1940s, the toy had developed into an iconic figure with a bright orange bill. Today, research has confirmed what many parents suspected tthe inside of these toys contain loads of bacterial and fungi growth.6

Throw Out the Duck With the Bathwater

The study was conducted by the Swiss Federal Institute of Aquatic Science and Technology and the University of Illinois. The researchers gathered 19 bath toys used under real-life conditions, analyzing them for notable biofilms on their inner surface.7 This study followed another completed several decades earlier, which suggested bath toys facilitated microbial growth, specifically the proliferation of pathogenic organisms such as pseudomonas or enterococcus.

In the late 1990s a multidrug-resistant outbreak of pseudomonas...

01:53

Theyre Just a Bunch of Crazy Mothers One #Crazymother Speaks Out and You Want to Hear What She has to Say "IndyWatch Feed Health"

working mothers collage image

There are only a handful of doctors in this country who know as much about vaccines as these parents do. Because once your child is injured by a vaccine, youll never stop researching it. Board Certified Pediatrician Dr. Bob Zajac

Commentary by Brian Shilhavy
Editor, Health Impact News

A very common tactic used by the corporate mainstream media, Big Pharma, and the government to try and convince the public that only uneducated people question vaccines, is to try and paint the debate as being between informed professionals, such as doctors and scientists, who they claim all agree that vaccines are safe and effective, and parents, particularly mothers, who are impassioned but ignorant when it comes to vaccine safety or efficacy.

We have spent considerable time debunking the first premise in this argument, and one can search and find many articles in our network with quotes and interviews from medical doctors and scientists who question vaccines.

The science is not settled.

But what about the second premise in this often-used argument? Are mothers really ignorant when discussing vaccine safety in regards to their children?

Who is the best expert to speak about the health of any given child, if not that childs mother? And in todays modern U.S. society, are not many of these mothers also among the doctors and scientists who speak out about vaccine safety?

Yes, they most certainly are, and we have featured many of these doctors and scientists here at Health Impact News.

Dr. Bob Zajac is a board-certified pediatrician who, by his own admission, used to be a vaccine bully who believed that parents that chose not to vaccinate were uninformed. But he began to notice that the patients in his practice who were not vaccinated, or under-vaccinated, tended to be healthier than those patients who followed the CDC vaccine schedule.

In an interview which we published on Hea...

01:39

As Much as We May Hate It, Its Stunning: 15 Cool Facts About the Brain "IndyWatch Feed Health"

If you're struggling with depression, anxiety, mania, or a combo package, you likely have a love/hate relationship with your brain. Still, you have to admit its design and work are just stunning. How 'bout we lighten things up and take a look at 15 cool brain facts? Tap on in...

01:19

Cocktail Sauce Recipe (mild, medium or spicy) "IndyWatch Feed Health"

cocktail sauce recipe, cocktail sauceWhether you order a shrimp appetizer at an upscale restaurant or a run-of-the-mill chain like Red Lobster or Shells, you are likely going to be served cocktail sauce on the side.

Combining seafood with a spicy sauce is an ancient practice. However, this uniquely American condiment did not become widely popularized until the Prohibition years of the 1920s and early 1930s. 

The post Cocktail Sauce Recipe (mild, medium or spicy) appeared first on The Healthy Home Economist.

01:11

Theyre Just a Bunch of Crazy Mothers One #Crazymother Speaks Out and You Want to Hear What She has to Say "IndyWatch Feed Health"

working mothers collage image

There are only a handful of doctors in this country who know as much about vaccines as these parents do. Because once your child is injured by a vaccine, youll never stop researching it. Board Certified Pediatrician Dr. Bob Zajac

Commentary by Brian Shilhavy
Editor, Health Impact News

A very common tactic used by the corporate mainstream media, Big Pharma, and the government to try and convince the public that only uneducated people question vaccines, is to try and paint the debate as being between informed professionals, such as doctors and scientists, who they claim all agree that vaccines are safe and effective, and parents, particularly mothers, who are impassioned but ignorant when it comes to vaccine safety or efficacy.

We have spent considerable time debunking the first premise in this argument, and one can search and find many articles in our network with quotes and interviews from medical doctors and scientists who question vaccines.

The science is not settled.

But what about the second premise in this often-used argument? Are mothers really ignorant when discussing vaccine safety in regards to their children?

Who is the best expert to speak about the health of any given child, if not that childs mother? And in todays modern U.S. society, are not many of these mothers also among the doctors and scientists who speak out about vaccine safety?

Yes, they most certainly are, and we have featured many of these doctors and scientists here at Health Impact News.

Dr. Bob Zajac is a board-certified pediatrician who, by his own admission, used to be a vaccine bully who believed that parents that chose not to vaccinate were uninformed. But he began to notice that the patients in his practice who were not vaccinated, or under-vaccinated, tended to be healthier than those patients who followed the CDC vaccine schedule.

In an...

00:27

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00:22

Protected: IQ Loss: Economic cost to society "IndyWatch Feed Health"

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Tuesday, 10 April

23:43

What World Health Organization Is Saying About Marijuana "IndyWatch Feed Health"

Recent reports indicate the World Health Organization (WHO) has deemed cannabidiol (CBD) as safe.  WHO has concluded that CBD, one of the main chemical components in marijuana, exhibits no effects indicative of any abuse or dependence potential.  A central talking point of the WHOs report is that CBD has been demonstrated as an effective treatment... View Article

The post What World Health Organization Is Saying About Marijuana appeared first on Healthy Holistic Living.

23:35

What a Mom Wished She Knew: How to Protect Your Child from Hand Foot and Mouth Disease "IndyWatch Feed Health"

For a lot of parents bringing their child to a public play place is a great form of exercise, it gets them moving and interacting with other kids. However, these places can also be a hub for bacteria exposing your child to viruses. Madelyn, a mom from the Philippines experienced this first hand when her... View Article

The post What a Mom Wished She Knew: How to Protect Your Child from Hand Foot and Mouth Disease appeared first on Healthy Holistic Living.

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