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Thursday, 18 January

22:48

How Much Apple Cider Vinegar Should You Drink? "IndyWatch Feed Health"

Apple cider vinegar is made from fermenting apples and has amazing health benefits. Drinking diluted apple cider vinegar can help to get rid of toxins from your body, assist in weight loss programs, and has cardiovascular benefits. So, you may be wondering how much apple cider vinegar you should drink to benefit your health.

Drinking the right amounts of apple cider vinegar a day to stay healthy isnt hard to do. At first, you might have to get used to the strong taste of diluted apple cider vinegar. However, you can add some delicious honey to improve its taste. This will help make sure that you are able to drink apple cider vinegar in the right quantities to benefit from it.

Consuming very large amounts of apple cider vinegar (ACV) daily has been associated with a mineral imbalance in the body. But, taking 2-4 tablespoons of apple cider vinegar is generally a safe amount. There are also some precautions with the daily dose of apple cider vinegar to avoid damaging tooth enamel or upsetting your digestive system.

In this article, I will look at how much apple cider vinegar per day you can safely drink. You will also find out how consuming small amounts of apple cider vinegar daily can help give your health a great boost.

What is Apple Cider Vinegar?

Apple cider vinegar has been used for centuries as a health tonic and to help disinfect wounds. Apple cider vinegar is made from fermenting apples and adding bacteria which converts the alcohol to acetic acid. This results in a liquid that has antiseptic properties and healthy bacteria.

According to the journal Medscape General Medicine, apple cider vinegar contains vitamins, minerals, amino acids, and polyphenolic compounds. This means that apple cider vinegar contains antioxidant compounds that can help kill off free radicals when consumed.1

The journal also said that among the benefits of drinking small amounts of apple cider vinegar daily are boosting cardiovascular health, controlling blood glucose levels, and ridding the body of toxins.

How Much Apple Cider Vinegar Should You Drink?

There is no official apple cider vinegar dosage per day. Because diluted apple cider vinegar has a strong taste, many people start off by drinking small amounts of apple cider vinegar diluted in a glass of water.

For example, you could start consuming 1 teaspoon of apple cider vinegar a day to begin with. Try this for a few days until you get used to the taste. Then, you could gradually increase the amount of ACV that you consume.

By a week or so, you should be drinking about 1-2 tablespoons of apple cider vinegar once or twice daily. This...

22:47

Abandoned and Denied Audio Bite #16 "IndyWatch Feed Health"

Dr. Sebi is known for sharing the message that BLACK PEOPLE cure AIDS. A message that he began subscribing to after realizing that the world was being deprived of the knowledge of his accomplishments because of the people who did not like him. A method that thousands of others could Continue reading

22:21

Medical Cannabis and Other Natural Potential Life-Saving Remedies for Chronic Obstructive Pulmonary Disease "IndyWatch Feed Health"

Disabled man. His life depends on his oxygen tank. Asthma emphysema COPD. He is using a rescue inhaler.

by Paul Fassa
Health Impact News

The pharmaceutical remedies for COPD (chronic obstructive pulmonary disease), which may seem to help at first, are side effect nightmares that most COPD sufferers abandon upon discovering other more natural solutions.

Pharmaceuticals also usually fail to stop the progression of COPD into the later stages that demand oxygen tanks as ones partner for life.

There are several natural options existing that can make life less miserable for COPD sufferers. One option is medical cannabis.

Its too early to tell if cannabis can completely cure one with COPD, meanwhile it serves to relieve the anxiety of not breathing well while simultaneously restoring normal breathing and providing relief by dilating bronchial tubes and healing lung tissue.

One of the pioneers who helped forge medical marijuana legislation in Oregon, Dr. Phil Leveque, who passed away in 2015 at the age of 90, has prescribed cannabis for over 5,000 patients and stated for the record:

Marijuana is one of the best bronchodilators, much better than any other class of drugs. For these respiratory diseases, [asthma and COPD] marijuana can be life-saving.

Dr. Leveque also claimed that smoking marijuana was not bad for the lungs, claiming cannabinoids are beneficial for lung tissues.

There are published studies that confirm Dr. Leveques assertion. In some cases, lung function increased with pot smokers who did not use tobacco cigarettes that are saturated with 600 added chemicals, mostly toxic and carcinogenic. (Source)

Studies that attest to support Dr. Leveques view may be accessed here.

Chronic Obstructive P...

22:17

Fertility outcomes can be improved by melatonin it enhances progesterone receptor expression. "IndyWatch Feed Health"

PMID:  Cell J. 2018 Apr ;20(1):108-112. Epub 2017 Dec 1. PMID: 29308626 Abstract Title:  Evaluating The Effect of Melatonin on HAS2, and PGR expression, as well as Cumulus Expansion, and Fertility Potential in Mice. Abstract:  OBJECTIVES: Infertility is a worldwide health problem which affects approximately 15% of sexually active couples. One of the factors influencing the fertility is melatonin. Also, protection of oocytes and embryos from oxidative stress inducing chemicals in the culture medium is important. The aim of the present study was to investigate if melatonin could regulate hyaluronan synthase-2 (HAS2) and Progesterone receptor (PGR) expressions in the cumulus cells of mice oocytes and provide an in vitro fertilization (IVF) approach.MATERIALS AND METHODS: In this experimental study, for this purpose, 30 adult female mice and 15 adult male mice were used. The female mice were superovulated using 10 U of pregnant mare serum gonadotropin (PMSG) and 24 hours later, 10 U of human chorionic gonadotropin (hCG) were injected. Next, cumulus oocyte complexes (COCs) were collected from the oviducts of the female mice by using a matrix-flushing method. The cumulus cells were cultured with melatonin 10M for 6 hours and for real-time reverse transcription-polymerase chain reaction (RT-PCR) was used for evaluation of HAS2 and PGR expression levels. The fertilization rate was evaluated through IVF. All the data were analyzed using a t test.RESULTS: The results of this study showed that HAS2 and PGR expressions in the cumulus cells of the mice receiving melatonin increased in comparison to the control groups. Also, IVF results revealed an enhancement in fertilization rate in the experimental groups compared to the control groups.CONCLUSIONS: To improve the oocyte quality and provide new approaches for infertility treatment, administration of melatonin as an antioxidant, showed promising results. Thus, it is concluded that fertility outcomes can be improved by melatonin it enhances PGR.

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21:56

Melatonin represses oral squamous cell carcinoma metastasis by inhibiting tumor-associated neutrophils. "IndyWatch Feed Health"

PMID:  Am J Transl Res. 2017 ;9(12):5361-5374. Epub 2017 Dec 15. PMID: 29312489 Abstract Title:  Melatonin represses oral squamous cell carcinoma metastasis by inhibiting tumor-associated neutrophils. Abstract:  Tumor-associated neutrophils (TANs) promote metastasis of multiple cancers, including oral squamous cell carcinoma (OSCC). Melatonin (Mel) reportedly exerts anti-metastatic effects on OSCC. However, little is known about the anti-OSCC effects of Mel involved in TANs. In this study, intensive infiltration of TANs was positively associated with advanced stage, lymphatic metastasis, and poor prognosis of OSCC. Moreover, Mel reduced the survival and migration of OSCC-associated neutrophils. Mechanistically, Mel suppressed the TAN release of C-X-C motif chemokine ligand 8, C-C motif chemokine ligand 2 (CCL2), CCL4, and matrix metalloproteinase-9 by blockage of p38 MAPK and Akt signaling. Mel-fostered TANs decreased the migration and invasion of OSCC cells and reduced tube formation in vitro. Additionally, Mel-hampered pro-motility and pro-angiogenesis effects of TANs were dependent on MMP-9 suppression in OSCC. Overall, The beneficial roles of melatonin in retarding OSCC metastasis were implicated with inhibition of TANs.

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21:42

Melatonin may be considered a possible therapy against trauma and sports related muscle injury. "IndyWatch Feed Health"

PMID:  J Sports Sci. 2018 Jan 9:1-5. Epub 2018 Jan 9. PMID: 29313427 Abstract Title:  Melatonin therapy for blunt trauma and strenuous exercise: A mechanism involving cytokines, NFB, Akt, MAFBX and MURF-1. Abstract:  Muscle injury occurs due to trauma, strenuous exercise or sports activities; most people affected are athletes. Ineffectively treated muscle injury can negatively affect sports careers and quality of life after retirement from sports. Reports have indicated that the current therapeutic management of muscle injury, particularly anti-inflammatory drugs, are not necessarily effective. Therefore, better therapies are required. Accumulating evidence has demonstrated melatonin's potent antioxidant and anti-inflammatory actions against musclepathology in sarcopenia or atrophy in systemic disease. However, the underlying mechanisms for the protective effect of melatonin in the context of trauma/strenuous exercise are multifactorial and not well described. This paper reviews data on melatonin's impact on muscle injury and findings that points toward the mechanisms through which melatonin achieves muscle protection. The general concept described in this review is that melatonin inhibits NFB, reduces cytokine expression, increases Akt that downregulates the ratio of MAFBX and MURF-1 in order to limit the extent of muscle injury andpromote muscle recovery post-injury. The work discussed in this review supports the notion that melatonin may be considered a possible therapy against trauma/sports related muscle injury. Inclusion of melatonin as a therapy in sports medicine could therefore provide a better treatment option for injured athletes and sports individuals.

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21:33

FORMER CAMPAIGN MANAGER: Trump must fulfill vaccine safety now with deep state on defense "IndyWatch Feed Health"

Roger Stone, Trumps former campaign head, is pulling few punches when he exclaims what he feels Trump needs to be doing in terms of vaccine safety in America. In an article written by Stone, which...

The post FORMER CAMPAIGN MANAGER: Trump must fulfill vaccine safety now with deep state on defense appeared first on Vaxxter.

21:24

Melatonin protects against A-induced neurotoxicity in primary neurons. "IndyWatch Feed Health"

PMID:  Biofactors. 2018 Jan 11. Epub 2018 Jan 11. PMID: 29322615 Abstract Title:  Melatonin protects against A-induced neurotoxicity in primary neurons via miR-132/PTEN/AKT/FOXO3a pathway. Abstract:  Alzheimer's disease (AD) is a kind of neurodegenerative disorder associated with age. Investigations suggest that amyliod- (A) is implicated in the pathogenesis of AD. The accumulation of A in the brain causes oxidative stress and synaptic toxicity, leads to synaptic dysfunction and neuronal death. Previous investigations suggest that melatonin an endogenous hormone can counteract A-induced neurotoxicity. However, the molecular mechanisms of A-induced toxicity and melatonin treatment remain elusive. Studies indicate that microRNA-132 is crucial for neuronal survival and plays a key role in the pathological process of AD. Moreover, PTEN and FOXO3a two key targets of miR-132 are upregulated in the AD brain. Here, we exposed the primary cultured cortical neurons with A25-35 and treated with melatonin. Our investigations demonstrated that A25-35 exposure significantly decreased the expression of miR-132 and elevated the expression of PTEN and FOXO3a. Whereas, melatonin treatment could rescue the expression of miR-132 and downregulate the level of PTEN and FOXO3a. Moreover, melatonin blocked the nuclear translocation of FOXO3a and thereby suppressed its pro-apoptotic pathways. In addition, our investigations suggested that the over-expression of miR-132 could block A-induced neurotoxicity.We also found that VO-OHpic (PTEN inhibitor) could counteract A-induced neuronal damage, and LY294002 (AKT inhibitor) suppressed the protective effect of melatonin. Together, these results indicate that melatonin exerts its neuroprotective effect in A-induced neurotoxicity via miR-132/PTEN/AKT/FOXO3a pathway. 2018 BioFactors, 00(00):000-000, 2018.

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21:15

Melatonin may increase cell survival in the hippocampus via decreasing oxidative stress and SIRT2 expression and increasing Bcl-2 expression. "IndyWatch Feed Health"

PMID:  Brain Res Bull. 2018 Jan 8 ;137:306-310. Epub 2018 Jan 8. PMID: 29325994 Abstract Title:  The effects of melatonin and curcumin on the expression of SIRT2, Bcl-2 and Bax in the hippocampus of adult rats. Abstract:  OBJECTIVE: Though the mechanisms are not clearly understood, melatonin and curcumin have been reported to have neuroprotective effects. However, the mechanisms of neuroprotective effects of melatonin and curcumin in the brain are not clearly understood. In the current study, we investigated the effects of melatonin and curcumin treatments on oxidative stress parameters, the expression of SIRT2, Bcl-2 and Bax in the hippocampus.METHODS: A total of thirty adult (13 months-old) male Wistar rats were divided into five groups: Control (1% ethanol:PBS), s.c. for 30days), dimethyl sulfoxide (10%, s.c. for 30days), Melatonin (10mg/kg/day, s.c. for 30days), Curcumin (30mg/kg/day, i.p. for 30days) and Salermide (100M, i.p. for 30days). The levels of malondialdehyde (MDA) glutathione (GSH) were measured as oxidative stress parameters in the hippocampus. The expression levels of SIRT2, Bcl-2 and Bax proteins were tested by western blotting and the SIRT2 protein levels of the hippocampal region was measured by a sandwich ELISA method.RESULTS: Melatonin and curcumin significantly decreased MDA and SIRT2 expression in the hippocampus (p

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21:09

This Will Kill 100 People Today But FDA Continues to Eliminate the Alternatives "IndyWatch Feed Health"

FDA opens a new front on the war against natural medicine.  Action Alert!

In the midst of an opioid epidemic that is killing nearly 100 people every day, the FDA has taken action against a natural medical food that offers patients an alternative to opioids.

Last November, the FDA posted a warning on its website concerning Limbrel, a medical food* marketed by Primus Pharmaceuticals for the management of osteoarthritis. Then, in December, the agency recommended that Primus voluntarily recall Limbrel. The stated reason for the warning is that the FDA is investigating serious adverse events involving Limbrel.  In a letter to Primus, the FDA states that 194 adverse event reports for Limbrel were received between 2007 and 2017about 20 a year.

Consider that NSAIDs (non-steroidal anti-inflammatory drugs), an alternative treatment for arthritis, cause approximately 107,000 hospitalizations every year, along with an estimated 16,500 deaths among arthritis patients alone.

Limbrels two main ingredients are Chinese skullcap and catechin, a flavonol and antioxidant found in blueberries and other fruits, as well as brewed tea, chocolate, and red wine. Chinese skullcap has been used safely in traditional Chinese medicine for many, many years.

Further, FDA asserts that Limbrel doesnt meet the definition of a medical food. To those familiar with the FDAs final guidance on medical foods, this should come as no surprise. As weve detailed previously, that guidance drastically limits the number of medical conditions that medical foods can claim to help manage. FDAs examples are restricted to rare genetic conditions that affect a small fraction of people, and are not applicable to patients who have more common disorders, no matter how controllable the condition might be with medical foods.

To give a sense for how outrageous the agencys thinking is on t...

21:06

Finally! Some Relief From Health Insurance Straight Jacket "IndyWatch Feed Health"

Help us support the first meaningful step in healthcare reform. Action Alert!

The Labor Department recently released its proposed regulations to implement President Trumps executive order by expanding association health plans.

Youll recall from our previous coverage that the executive order expands association health plans, also known as small group health plans. The idea is that individuals with a common profession or interest should be able to band together and count as a large group for health insurance purposes. Importantly, these plans are exempted from certain Obamacare requirements, such as covering essential health benefits. Large-group plans also have more leeway in setting premiums, which can be based on the health of the group (currently barred under the Obama-era rules).  Associations that gain large-group status could therefore offer less expensive, less expansive coverage if they were made up mainly of healthier members.

The Labor Department estimates that as many as 11 million Americans could get coverage under this proposal, which moves toward establishing the parallel, consumer-driven health care system that ANH advocates.

Action Alert! Write to the Labor Department and tell them you support expanding access to association health plans as a means of providing more freedom of choice in health care. Please send your message immediately.

20:14

Tennessee Kidnaps 3 Boys from Mentally Disabled Mom Refuses Grandmother Custody in Favor of Adoption to Strangers "IndyWatch Feed Health"

Whitney 3 brothers

Adoptable brothers Bentyn, Ethyn, and Kamdyn were taken from a disabled mother and are now cut off from all family members. Photo provided by family.

by Health Impact News/MedicalKidnap.com Staff

A grandmother is fighting to save 2 generations of her family from abuse by the state of Tennessee. Through no fault of her own, her family is being ripped apart, in a terrifying sequence of events that could happen to anyone.

She is afraid for 3 of her grandsons who were seized by Tennessee Department of Childrens Services (DCS) from their mentally disabled mother. They have suffered horrific abuse in foster care. Now the state is attempting to sever all family ties so that they can adopt them out to strangers.

She is also fearful for the life of her 33 year old daughter Tara, the boys mother, whose mental illness became much worse after the boys were taken. When they learned of the abuse of the boys in foster care, the sense of utter helplessness to protect them pushed her daughter over the edge.

The law provides for families to do what families do for those members who are capable to step in and help other family members who are incapacitated in some way.

However, in this familys case, the state seems determined to keep that from happening.

Violation of Civil Rights for Disabled Mom

Whitney and Tara

Whitney Manning (left) with her daughter Tara. Photo provided by family.

Whitney became conservator over her daughters affairs when Taras mental health declined to the point where she couldnt take care of them on her own.

Tara has suffered from depression, anxiety, bipolar disorder, and ADHD for many years. Since her children were taken, Tara has declined dramatically. She has now been diagnosed with psychosis and schizoaffective disorder.

There are provisions in th...

20:01

The proliferations of Caco-2, MCF-7, and HELA cells were more inhibited when treated with water-soluble extract of fermented camel milk extracts. "IndyWatch Feed Health"

PMID:  J Dairy Sci. 2018 Feb ;101(2):900-911. Epub 2017 Dec 8. PMID: 29224862 Abstract Title:  In vitro investigation of anticancer, antihypertensive, antidiabetic, and antioxidant activities of camel milk fermented with camel milk probiotic: A comparative study with fermented bovine milk. Abstract:  This study aimed to investigate in vitro anticancer activity by antiproliferative activity, antihypertensive activity by angiotensin-converting enzyme inhibition, antidiabetic activity by-amylase and -glucosidase inhibitions, and antioxidant activities of camel milk fermented with camel milk probiotic compared with fermented bovine milk. The camel milk probiotic strain Lactococcus lactis KX881782 (Lc.K782) and control Lactobacillus acidophilus DSM9126 (La.DSM) were used to prepare fermented camel and bovine milks separately. The proteolytic activities of water-soluble extract (WSE) in all fermented camel milk were higher than those in fermented bovine milk. The -glucosidase inhibitions in both milk types fermented by Lc.K782 ranged from 30 to 40%. Camel milk fermented byLc.K782 had the highest antioxidant activity by 2,2'-azino-bis(3-ethylbenzo-thiazoline-6-sulphonic acid). The highest angiotensin-converting enzyme inhibition of WSE in camel milk fermented by Lc.K782 was>80%. The proliferations of Caco-2, MCF-7, and HELA cells were more inhibited when treated with WSE of fermented camel milk extracts.

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19:51

7 Tips to Choose and Get the Most out of a CSA "IndyWatch Feed Health"

Become a CSA Member: Invest in Local Farms, Reap Delicious Rewards

With the New Year already in motion, we are quickly approaching the season of plentiful fruits and vegetables. It wont be long until we are enjoying a bounty of fresh cut greens, spicy arugula, spring onions, strawberries and, soon enough, juicy tomatoes and buttery potatoes! So how can you ensure these goodies make it to your table? You can join a local CSA Community Supported Agriculture!

What it Means for the Farm

Owls Nest Farm CSA

Photo: Owls Nest Farm

When signing up for a CSA share, a customer becomes a direct investor in their farm of choice. At the beginning of the farm season, people pay up front for a share that will typically last the entire growing season (though some farms offer extended CSAs that start early and end late.) By paying up front, customers are insuring cash flow to the farmer regardless of ebbs and flows in the growing period.

On weeks when their harvest might be a little smaller due to unpredicted outside forces or transitioning crops, the farmer wont have to take as substantial of a cut to sales. But dont worry, when the farmer exp...

19:34

The beneficial effect of the intake of a hazelnut capsule on the methylation levels of the ADRB3 gene was demonstrated for the first time. "IndyWatch Feed Health"

PMID:  Clin Epigenetics. 2017 ;9:110. Epub 2017 Oct 13. PMID: 29046732 Abstract Title:  Effect of a diet containing folate and hazelnut oil capsule on the methylation level of the ADRB3 gene, lipid profile and oxidative stress in overweight or obese women. Abstract:  BACKGROUND: Studies of genes that play an important role in the development of obesity are needed, especially studies focusing on genes that regulate food intake and affect nutrient metabolism. For example, the beta-3 adrenergic receptor (ADRB3) responds to noradrenaline and mediates lipolysis in adipocytes.METHODS: This was a controlled intervention study involving 40 overweight and obese adult women in which food intake, anthropometric measurements, biochemical analyses, and methylation levels of the ADRB3 gene were evaluated before and after intervention. The individuals were randomized into four groups: group 1 (G1) received 300 g of vegetables and legumes containing on average 191 g/day of folate and 1 hazelnut oil capsule; group 2 (G2) received 300 g of vegetables and legumes containing on average 191 g/day of folate and 1 placebo capsule; group 3 (G3) received 300 g of vegetables and legumes containing on average 90 g/day of folate and 1 hazelnut oil capsule; and individuals in group 4 (G4) were only followed-up and maintained their regular dietary habits. Statistical analysis was performed using analysis of variance (ANOVA), Student's t test and simple regression, using STATA 13 software.RESULTS: In the total sample, after the intervention, the women classified as overweight and obese did not present weight loss, and there was a reduction in the methylation levels of the ADRB3 gene and malondialdehyde, as well as an increase in high-density lipoprotein cholesterol and total antioxidant capacity.CONCLUSIONS: The beneficial effect of the intake of a hazelnut capsule on the methylation levels of the ADRB3 gene was demonstrated for the first time.TRIAL REGISTRATION: ClinicalTrials.gov, NCT 02846025.

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19:29

Tennessee Kidnaps 3 Boys from Mentally Disabled Mom Refuses Grandmother Custody in Favor of Adoption to Strangers "IndyWatch Feed Health"

Whitney 3 brothers

Adoptable brothers Bentyn, Ethyn, and Kamdyn were taken from a disabled mother and are now cut off from all family members. Photo provided by family.

by Health Impact News/MedicalKidnap.com Staff

A grandmother is fighting to save 2 generations of her family from abuse by the state of Tennessee. Through no fault of her own, her family is being ripped apart, in a terrifying sequence of events that could happen to anyone.

She is afraid for 3 of her grandsons who were seized by Tennessee Department of Childrens Services (DCS) from their mentally disabled mother. They have suffered horrific abuse in foster care. Now the state is attempting to sever all family ties so that they can adopt them out to strangers.

She is also fearful for the life of her 33 year old daughter Tara, the boys mother, whose mental illness became much worse after the boys were taken. When they learned of the abuse of the boys in foster care, the sense of utter helplessness to protect them pushed her daughter over the edge.

The law provides for families to do what families do for those members who are capable to step in and help other family members who are incapacitated in some way.

However, in this familys case, the state seems determined to keep that from happening.

Violation of Civil Rights for Disabled Mom

Whitney and Tara

Whitney Manning (left) with her daughter Tara. Photo provided by family.

Whitney became conservator over her daughters affairs when Taras mental health declined to the point where she couldnt take care of them on her own.

Tara has suffered from depression, anxiety, bipolar disorder, and ADHD for many years. Since her children were taken, Tara has declined dramatically. She has now been diagnosed with psychosis and schizoaffective disorder.

There are provisions in the A...

19:25

Drink of death: Agras dark secret "IndyWatch Feed Health"

Agra home to the Taj Mahal plus other Mughal-era monuments is a magnet for tourists, both domestic as well as foreign.

And besides lugging their cameras, tote bags and ruck sacks tourists carry the ubiquitous water bottles. For among Agras darkest secrets is the citys undrinkable water.

Recently the Agra administration got the water in Agra tested and it was found that in most of the Agra district, the fluoride levels in the water are way higher than the World Health Organization (WHO) standards.

A senior water works official told India Today that in five districts of Uttar Pradesh, the subsoil water has been found to have higher than normal fluoride levels.

The Central government has issued an alert, asking the UP government to take immediate action to resolve this situation.

He said that the affected UP districts include Agra, Ghazipur, Jhansi, Sonbhadra and Varanasi. Earlier Unnao, Raibareli, Firozabad, Mathura and Pratapgarh had also been counted in the fluoride-affected districts.

Since 2009 the National Fluorosis Prevention and Control Programme has been running in UP with the state government operating water-testing laboratories in the initially identified fluoride affected districts

There has been a growing chorus for more funds to establish labs and buy equipment and reagents; theres also the need for more manpower.

According to the health department sources, when the fluoride content of water rises above 1-1.5 parts per million (ppm), it starts creating health related issues fluorosis in the people drinking this water. This limit has been fixed by the WHO.

Fluorosis damages teeth and bones, according to Dr SK Kalra, a senior physician. He said that the early signs of the disease are vomiting, loss of appetite, flatulence, bloating, yellowing teeth, frequent urination, excessive thirst, joint pain, hunched back and crooked legs among others.

Dr Sushma Singh, deputy director of State Institute of Health and Family Welfare said that the central government has notified five districts that are affected by fluorosis and water-testing labs are being established there, for which budget has been requested under the National Health Mission.

Excessively high fluoride content causes Fluorosis

Health Department: When fluoride content of water rises above 1-1.5 ppm, it starts creating health related issues fluorosis.

In Patti Pachgai vill...

18:58

Effect of fluoride on brain of albino-rabbit An experimental study. "IndyWatch Feed Health"

From Table 1: Gross and brain cyto-architecture changes of experimental animals at the end of 16 weeks.

Changes in Brain Cytoarchitecture: The neurones lost their angular or pyramidal shape and acquired a plump, ovoid, rounded, or characteristic ballooned appearance (Figure 1). The nucleus was displaced to the periphery or axonal base and was shrunken, pyknotic, or absent. Reduction in the number of Purkinje neurones and in some areas even complete loss of neurones. Pyramidal neurones exhibited chromatolysis, Nissl substance was not detectable, and the perikaryon was filled with numerous small colorless vacuoles (Figure 2). Neuroglial cells showed chromatolysis, and in the neuroplasm of these cells, one or two spheroid bodies were present. The nucleus was located at the periphery of the cell (Figure 3).

18:22

Being Bilingual Helps Autistic Children "IndyWatch Feed Health"

By Mae Chan

Children with Autism Spectrum Disorders (ASD) often have a hard time switching gears from one task to another. But being bilingual may actually make it a bit easier for them to do so, according to a new study which was recently published in Child Development.

Research has shown just how childrens brains can become bilingual so easily, findings that scientists hope eventually could help even those with autism.

This is a novel and surprising finding, says Prof. Aparna Nadig, the senior author of the paper, from the School of Communication Sciences and Disorders at McGill University. Over the past 15 years there has been a significant debate in the field about whether there is a bilingual advantage in terms of executive functions. Some researchers have argued convincingly that living as a bilingual person and having to switch languages unconsciously to respond to the linguistic context in which the communication is taking place increases cognitive flexibility. But no one has yet published research that clearly demonstrates that this advantage may also extend to children on the autism spectrum. And so its very exciting to find that it does.

The researchers arrived at this conclusion after comparing how easily 40 children between the ages of six and nine, with or without ASD, who were either monolingual or bilingual, were able to shift tasks in a computer-generated test. There were ten children in each category.

Blue rabbits or red boats

The children were initially...

18:10

2 Minute Warning- January 18, 2018 "IndyWatch Feed Health"

This weeks featured stories:

 

18:06

The Dangers of Processed Foods Exposed in Numerous Studies "IndyWatch Feed Health"

By Anna Hunt

To many people, news and research about the positive effects of superfoods are sufficient motivation to eat healthy. Yet, sometimes we need a stark reminder of the dangers of processed foods to stay on track with our diet goals.

When you go into the grocery story, an overwhelming majority of the foods sold have been altered form their natural state. Typically, this is done to make things more convenient for the consumer.

One can categorize processed foods into groups. First, there are minimally and semi-processed foods. These include frozen vegetables, fruit juice, roasted nuts, white rice, etc. These are typically very similar to natural foods and are most-often an acceptable part of a healthy diet.

The second category are ultra-processed foods. In this category, producers use chemicals, food additives, nitrates, salts, food dyes, etc. in the production of food products. Five of the most-commonly eaten foods in the U.S. are all ultra-processed: sugary soft drinks, cakes and pastries, burgers, pizza, and chips.

Below are three pieces of recent research that emphasize what might happen when your diet consists of too many of these ultra-processed and chemical-ridden foods.

One of the Dangers of Processed Foods is Cancer

Canadian researchers recently published a study that attributed to 41% of the instances of cancer to lifestyle and environmental factors. Personal choices when it comes to diet ranked very high on the list. The study stated...

18:03

10 Ways to Prepare for WWIII "IndyWatch Feed Health"

prepare WW3

By Jeremiah Johnson 

By now youre poignantly aware of the false-alarm that was raised in Hawaii on Saturday 1/13/18.  For 38 minutes there was wholesale panic and alarm after the following message alert was sent out to cell phones and over the TV and radio throughout the state:

BALLISTIC MISSILE THREAT INBOUND TO HAWAII. SEEK IMMEDIATE SHELTER. THIS IS NOT A DRILL.  (Hawaii Emergency Management Agency)

This message was later rescinded as a false-alarm.  Great, huh?  In the meantime, people panicked.  News reports told of people gathered in hotel lobbies in a state of semi-paralysis, wondering what to do.  One woman (a schoolteacher) attempted to enter a shelter only to find that it was locked.  A professional golfer and his family hid beneath a mattress in the bathroom of a hotel, hoping the attack was not happening.  Other people placed their children inside of storm drains, and still others called authorities with no answer.

Preparing Falls to You

The bottom line: the government was not prepared to deal with it had it been an actual emergency, and individuals were next to helpless in the face of the threat.

The government will not be able to help you, even...

17:48

Aluminum and fluoride impacts cortex and hippocampus structure in rats: protective role of resveratrol. "IndyWatch Feed Health"

from Results and Discussion:

The neuronal damage and aggregation was observed in AlCl 3 + NaF treated group when compared to the control group where as less neuronal damage and aggregation was observed when Resveratrol administered along with AlCl 3 + NaF treatment. No morphological variation was observed in Resveratrol alone treated group as compared to the control group.

The amyloid protein plaques were formed in the AlCl 3 +NaF treated group as compared to the control group. The amyloid plaques were not observed in the Resveratrol along with AlCl 3 +NaF treated group as compared to the AlCl 3 +NaF treated group.

17:32

Neuroprotective effects of curcumin on sodium fluoride induced behavioural and enzymatic changes in brain and muscles of rat "IndyWatch Feed Health"

from Results and discussion:

The present study evidenced that sodium fluoride consumption showed alteration in motor, cognitive, nociceptive behaviour and induced significant changes in the oxidative stress; membrane bound enzymes activities in rat. The administration of curcumin simultaneously with sodium fluoride reduced the oxidative stress, increased enzymes activities and improved behavioural abilities in rats. Vani and Reddy (2000) reported decreased somatic index of muscle and brain in fluoride treated mice. It is evidenced in the present study that the body weight and organo somatic index (OSI) (Fig. 1a, b) of muscle (-26.72%) and brain (-15%) of fluoride exposed rats were decreased significantly (p<0.05) as compared to control, whereas the NaF+Curcumin treated group showed increased OSI of brain (-5.71%) and muscle (-10.34%) as compared to fluoride administered rats and results were nearer to control rats (p<0.05). The body, brain and muscle weights were proportionately reduced in fluoride treated rats as compared to control group individuals and improved in the above weights in curcumin received rats.

17:00

Is our database missing a retraction? Tell us! "IndyWatch Feed Health"

As many readers know, weve been hard at work curating a comprehensive database of retractions, and are now up to more than 16,000 entries. Despite that large number as much as triple what youll find in commonly used databases we know there are notices were missing. Were doing our best to fill in []

The post Is our database missing a retraction? Tell us! appeared first on Retraction Watch.

16:53

These results indicate a chemopreventive potential of in vitro fermented hazelnuts. "IndyWatch Feed Health"

PMID:  Anticancer Res. 2018 01 ;38(1):83-93. PMID: 29277760 Abstract Title:  Chemopreventive Potential of In Vitro Fermented Raw and Roasted Hazelnuts in LT97 Colon Adenoma Cells. Abstract:  BACKGROUND/AIM: Due to their unique composition of health-promoting compounds, the consumption of hazelnuts may contribute to the prevention of colon cancer.MATERIALS AND METHODS: Since hazelnuts are often consumed roasted, the impact of different roasting conditions (RC1=140.6C/25 min, RC2=155.1C/20 min and RC3=180.4C/21 min) on chemopreventive effects of in vitro fermented hazelnuts was analyzed in LT97 colon adenoma cells.RESULTS: FS (2.5%) of raw and roasted hazelnuts reduced H2O2-induced DNA damage while 5% FS significantly induced gene expression of SOD2 (3.0-fold) and GSTP1 (2.1-fold). GPx1 mRNA levels were significantly decreased (0.6-fold) by FS (2.5%). The growth of LT97 cells was significantly reduced by hazelnut FS in a time- and dose-dependent manner. Hazelnut FS (5%) increased the numbers of early apoptotic cells (9.6% on average) and caspase-3 activities (6.4-fold on average).CONCLUSION: These results indicate a chemopreventive potential of in vitro fermented hazelnuts which is largely unaffected by the roasting process.

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16:41

A review of almond, hazelnut and walnuts for neuroprotection in Alzheimer's disease. "IndyWatch Feed Health"

PMID:  Pharmacol Res. 2017 Dec 5. Epub 2017 Dec 5. PMID: 29208493 Abstract Title:  Almond, hazelnut and walnut, three nuts for neuroprotection in Alzheimer's disease: A neuropharmacological review of their bioactive constituents. Abstract:  An increase in the prevalence of Alzheimer's disease (AD) as a multifactorial neurodegenerative disorder is an almost obvious issue in the world. Researches on natural products for finding effective drugs to prevent the disease are in progress. There is special attention to the three types of nuts including almond, hazelnut and walnut in manuscripts of traditional Persian medicine (PM) as the preventive agents against brainatrophy and memory loss. The purpose of this study is a pharmacological review of their bioactive constituents and introducing the value of these nuts as the effective supplements and natural medicinal foods in AD patients. Databases including PubMed and ScienceDirect were searched in title, abstract and keywords from year 2000 to present for AD-related researches on these tree nuts, their major phytochemicals and their mechanisms of action. As result, almond, hazelnut and walnut provide macronutrients, micronutrients, and phytochemicals which affect several pathways in AD pathogenesis such as amyloidogenesis, tau phosphorylation, oxidative stress, cholinergic pathways, and some non-target mechanisms including cholesterol lowering and anti-inflammatory properties, as well as effect on neurogenesis. These nuts are recommended in PM for their brain-protective activity and particularly reversing brain atrophy in case of hazelnut. The therapeutical statements of PM scholars mentioned in their books are based on their clinical observations with support of a long history of experiences. Beyond the molecular activities attributed to the phytochemicals, the use of these tree nuts could be more considered in scientific researches as the effective nutrients for prevention or even management of AD.

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16:18

HHS establishes a new Conscience and Religious Freedom (CRF) Division within its Office for Civil Rights, holds livestream today, Jan 18th at 10:30am EST. "IndyWatch Feed Health"

by Ginger Taylor HHS establishes a new Conscience and Religious Freedom (CRF) Division within its Office for Civil Rights, holds livestream today, Jan 18th at 10:30am EST. The religious rights of families in Mississippi, California and West Virginia, along with...

16:13

ABC News Features Dr. Tenpennys Vaccine Info Page "IndyWatch Feed Health"

Mainstream media is trying to figure out why the antivaccine movement is so big, active, and intelligent. Yesterday, ABCs Australian affiliate ran a story that discussed the concept of filter bubbles. The idea being that...

The post ABC News Features Dr. Tenpennys Vaccine Info Page appeared first on Vaxxter.

16:08

New California Wants to Break Away From Tyranny of California, Create 51st State "IndyWatch Feed Health"

Source: New California Wants to Break Away From Tyranny of California, Create 51st State For more content like this visit REALfarmacy.com.

by CAREY WEDLER Over the years, there have been several secession efforts in California aimed at breaking away from the U.S. government, including one that gained steam following Donald Trumps election in 2016. So far, none have been successful, but a new declaration from rural communities are now seeking independence not from the U.S., but from California itself. []

Source: New California Wants to Break Away From Tyranny of California, Create 51st State Learn more at REALfarmacy.com - Healthy News and Information.

15:53

From Picket Lines to Worry Lines "IndyWatch Feed Health"

Review: Iain Ferguson, Politics of the Mind: Marxism and Mental Distress. 2017, London: Bookmarks. 134 pages.

Iain Ferguson has experience as a psychiatric social worker, social work academic, socialist, trade unionist, and co-founder of Social Workers Action Network (SWAN) which advocates building unity in action between campaigning organizations of service users on the one hand and carers organizations on the other to prevent service cuts and closures. While his book addresses the U.K. and European experience, the basic arguments apply everywhere.

Ferguson aims to use the marxist approach not only to make sense of mental distress but also help us address and change the material conditions that give rise to it.

the central argument of this book is that it is the economic and political system under which we live  capitalism  which is responsible for the enormously high levels of mental health problems which we see in the world today.

He begins by describing the crisis in mental health that disproportionately affects the unemployed, poor, and oppressed. He attributes this crisis to rising poverty, increased work stress, the shredding of social supports, and a low level of class struggle. Workers feel more burdened, more alone, and less hopeful, leaving the picket lines of the past to join the worry lines of the present.

Ferguson emphasizes that the meaning people give to their experience can make the difference between sinking into despair and fighting back. If a worker interprets the loss of her job as a sign of personal unworthiness, she is more likely to sink into depression than if she recognizes that unemployment is necessary to capitalism and feels anger at being victimized.

In the chapter All in the brain? Ferguson critiques and rejects the medical model of mental distress, the DSM, the medicalization of everyday life, and the horrible history of psychiatric crimes. He concludes by briefly reviewing the challenge to biological psychiatry posed by social models of distress.

Ferguson points out that the model of social adversity is preferable to the model of faulty biology. However, it fails to acknowledge the class conditions that generate trauma. As a result, trauma is typically treated as an individual or individual-family problem instead of an intrinsic feature of capitalism. This enables right-wingers to attack distressed families for failing to support their childrens mental development, when studies show that raising family incomes is the most effective way to do this.

The final chapter presents Marxs theory of alienation as a means to understand the causes of mental distress and how to challenge them. Most people experience alienation as a lack of control over the...

15:41

President Trump Urged to Move on Vaccines by Former Campaign Head Roger Stone "IndyWatch Feed Health"

Roger Stone Says: Now that hes got the Deep State on defense, he should press his advantage by fulfilling his promises that gained him cross-party support that helped get him elected. He must move forward with his promise of appointing Robert F. Kennedy, Jr. to lead a Vaccine Safety Commission. Roger Stone, former head Continue reading President Trump Urged to Move on Vaccines by Former Campaign Head Roger Stone

The post President Trump Urged to Move on Vaccines by Former Campaign Head Roger Stone appeared first on BolenReport.

14:00

A painful lesson: Authors retract paper after discovering mislabeled mouse lines "IndyWatch Feed Health"

Neuroscientists have retracted a 2016 paper examining the genetic underpinnings of a degenerative motor neuron disease, after discovering that two mouse lines had been accidentally mislabeled. According to the retraction notice, published in December in Acta Neuropathologica Communications, mice engineered to have a specific genetic mutation were mislabeled as the normal or wild type group. []

The post A painful lesson: Authors retract paper after discovering mislabeled mouse lines appeared first on Retraction Watch.

13:20

Dangerous New Trend: Tide Pod Challenge Gone Deadly 2018 "IndyWatch Feed Health"

Source: Dangerous New Trend: Tide Pod Challenge Gone Deadly 2018 For more content like this visit REALfarmacy.com.

Headlines are being made about millennials eating Tide Pod laundry detergent tablets. One from Unilad reads: Millennials Eating Washing Tablets Thanks To Stupid Tide Pod Challenge But people arent really eating laundry pods: at least 99.99% of people joking about it. Only the most elite crop of stupid people in the millennial generation would actually take []

Source: Dangerous New Trend: Tide Pod Challenge Gone Deadly 2018 Learn more at REALfarmacy.com - Healthy News and Information.

12:24

Extracting Electricity From Temperature Differences "IndyWatch Feed Health"

What if you could run your air conditioner not on conventional electricity, but on the sun's heat during a warm summer's day? With advancements in thermoelectric technology, this sustainable solution might one day become a reality.

12:03

Mental Health Inc: A New Book by Art Levine "IndyWatch Feed Health"

From AlterNet: A new book my Art Levine, Mental Health Inc: How Corruption, Lax Oversight and Failed Reforms Endanger Our Most Vulnerable Citizens, exposes the greed and cronyism behind the countrys epidemic of psychiatric overmedication and malpractice.

Article

12:02

Histories of Violence: Neurodiversity and the Policing of the Norm "IndyWatch Feed Health"

In this interview for the Los Angeles Review of Books, cultural theorist and philosopher Erin Manning discusses neurodiversity, a movement that seeks to depathologize traits, experiences, and ways of existing that are categorized as disorders. Manning critiques the education systems inherent enforcement of neurotypicality and marginalization of those who diverge from the norm.

Neurodiversity is a movement that celebrates difference while remaining deeply nuanced on questions of (medical) facilitation and the necessity of rethinking the concept of accommodation against narratives of cure. The added emphasis on neurology has been necessary in order to challenge existing norms that form the base-line of existence: the neuro in neurodiversity has opened up the conversation about the category of neurotypicality and the largely unspoken criteria that support and reinforce the definition of what it means to be human, to be intelligent, to be of value to society. This has been especially necessary for those folks who continue to be excluded from education, social and economic life, who are regarded as less than human, whose modes of relation continue to be deeply misunderstood, and who are cast as burdens to society.

12:01

Why Its Time to Let Psychoanalysis Into Politics "IndyWatch Feed Health"

In this piece for Prospect, Susie Orbach explains how insights from psychoanalysis can help us understand our current political, social, and economic climate.

Politically, socially, ecologically and economically, we live in fragile times. The psychic fragilities are not confined to the poor who are the more obvious victims of the way weve been running the economy and society these last few decades. We could think of how they also exist for the very wealthy through the case of Harvey Weinstein. His constant predatory behaviour speaks to a kind of power so unsure of itself it needs constant confirmation and reiteration. If the power were not felt deep inside to be conflictual, it wouldnt need continual enactment. We see this in the consulting room, in which solutions are sought to expel pain and insecurity. If things run in a way which fosters more pain and insecurity, we can expect more of the addictive and hurtful patterns as well as the monstrous behaviours which are often a carapace for underlying vulnerabilities.

If fragility is the defining feature of our times, it is also what we therapists have always dealt with. With questions and worries and uncertainties, we endeavour to hold a frame while individuals, couples and groups, explore the multiple meanings of their dilemmas. People come to therapy looking for certainties.  We destabilise such notions because the process of self-reflection necessarily upends knowns. In the exploration of uncertainties, we discover societys hurts, the costs of hyper-masculinity, hyper-femininity and the fragile identities of  whiteness and class which mark allegiances which are often not in our best interests.

12:00

Trauma Resiliency Model: A New Somatic Therapy for Treating Trauma "IndyWatch Feed Health"

A mask, painted by a Marine who attends therapy for PTSD. (Official U.S. Marine Corps photo by Cpl. Andrew Johnston)

12:00

American Teens Eating A Big Bowl of Stupid: Laundry Detergent "IndyWatch Feed Health"

By Kim Rossi There's no kind way to say this, so I won't attempt to hide my scorn, not at the kids but the system. American kids who are eating Tide laundry soap packets are not well. Yes, kids will...

11:59

James Lyons-Weiler PhD "New York Times Has Lost It" "IndyWatch Feed Health"

Note: Vaccination rights continue to be a major issue facing Americans - despite most having no inkling or care about the topic. Until someone they love is vaccine injured. Thanks to James Lyons-Weiler for this article on the state of...

07:56

Public perception of community water fluoridation in the UK "IndyWatch Feed Health"

Teeside University are running a survey to gauge the public opinion in the UK regarding fluoridation of drinking water at online at https://teesside.onlinesurveys.ac.uk/public-opinion-on-water-fluoridation-in-the-uk

Page 1: Consent Form

1. The purpose of the survey is to gauge the public opinion in the UK regarding fluoridation of drinking water. It should take about 10 minutes to complete.  Participation is voluntary, and you may exit the survey at any time. If you would like to be included in the prize draw and/or participate in an additional interview by email, then kindly provide your e-mail address when prompted. If you choose to provide your email address, your survey responses may no longer be anonymous to the researcher but will remain confidential. There are no foreseeable risks to you for taking part in this study. By completing and submitting the survey online you are giving your informed consent to take part in this study. By clicking I agree below you are indicating that you are at least 18 years old, resident in the UK and voluntarily agree to participate in this research survey. Required.

Page 2: Personal Details

3. What is your age? Required
4. Gender Required
5. Please specify your Ethnicity Required
...

07:30

Cancer quack Colleen Huber sues Britt Hermes over criticism "IndyWatch Feed Health"

Naturopathic cancer quack Colleen Huber is attempting to silence criticism of her practices by suing Britt Hermes. Help Britt fight back with a donation to help defray legal expenses.

07:00

Depression Not Caused by Chemical Imbalance "IndyWatch Feed Health"

By Dr. Mercola

Do you know what causes depression? Many people would respond that its due to a chemical imbalance in the brain. This chemical imbalance theory has been widely promoted by drug companies and psychiatrists alike, to the extent that its accepted as fact. The glaring problem is that the chemical imbalance theory is just that a theory and worse still, its a theory that has been largely discredited.

The theory was first proposed by scientists in the 1960s after it appeared certain antidepressant drugs worked by altering brain chemicals, but it was stated that the findings are inconclusive.1 Yet, the theory was proposed at a time when treating mental illness via psychoanalysis was falling out of favor while viewing it as tied to a physical or biological mechanism was in vogue.

The idea quickly spread, becoming the medical dogma for depression, despite concrete evidence proving its worth. The fact that practicing physicians and leaders of science bought that idea, to me, is so disturbing, Steve Hyman, director of the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard, told Quartz.2 The news outlet continued:

Its not hard to see why the theory caught on: It suited psychiatrists newfound attempt to create a system of mental health that mirrored diagnostic models used in other fields of medicine. The focus on a clear biological cause for depression gave practicing physicians an easily understandable theory to tell patients about how their disease was being treated.3

Prozac, Zoloft Bring Chemical Imbalance Theory for Depression to the Mainstream

The release of the antidepressant Prozac (fluoxetine) in the late 1980s was a game changer for depression treatment in that the drugs maker, Eli Lilly, heavily promoted the chemical balance theory as a marketing gimmick to sell the drug. With fewer side effects than some of the earlier antidepressants, Prozac became a blockbuster drug and the poster child for the selective serotonin reuptake inhibitor (SSRI) class of antidepressants, which target the neurotransmitter serotonin.

There was, of course, no demonstrable evidence showing that depressed patients had any imbalance, but Lilly ran with it, Psychology Today noted. Before long, psychiatrists and psychiatric patients alike came to identi...

Get Proper Sleep Nightly "IndyWatch Feed Health"

30 Tips in 30 Days Designed to Help You Take Control of Your Health

This article is part of the 30 Day Resolution Guide series. Each day a new tip will be added designed to help you take control of your health. For a complete list of the tips click HERE

By Dr. Mercola

Lack of sleep has been scientifically linked to a wide array of health problems and is so common, its been identified as a public health epidemic by the U.S. Centers for Disease Control and Prevention. A review of hundreds of sleep studies concluded that, as a general rule, most adults need somewhere between seven and nine hours or right around eight hours of sleep per night to maintain good health.

Your body, indeed every organ and even individual cells, contains biological clocks that regulate everything from metabolism to psychological functioning. Even half your genes have been shown to be under circadian control, turning on and off in cyclical waves.

All of these body clocks are synchronized to your master circadian clock, situated in your brain, which in turn is synchronized to the rising and setting of the sun, provided you dont confuse it with artificial lighting at night and/or insufficient sunlight during the day, that is. Over the long term, skimping on sleep which is a surefire way to dysregulate your circadian body clock can contribute to a whole host of chronic health problems.

Lack of Sleep Puts Your Health at Risk

Research has shown that insufficient sleep and/or poor quality sleep can increase your risk for:

Accidents at work and on the road

Getting less than six hours of sleep leaves you cognitively impaired. In 2013, drowsy drivers caused 72,000 car accidents in which 800 Americans were killed and 44,000 were injured.1 Even a single night of sleeping only four to six hours can impact your ability to think clearly the next day.

Weight gain

Getting less than seven hours of sleep per night has been shown to raise your...

06:55

Its time to chlorinate New Zealands drinking water "IndyWatch Feed Health"

At the artesian drinking-water fountain in Petone, theres often a small queue of people waiting to fill big bottles with the famously crisp Wellington water. The districts town water supply has long been chlorinated: hence the Petone fountains attraction. We value water purity and taste and will go out of our way to get the natural, untreated product.

So it is no surprise that officials suggestion that all drinking water be chlorinated has caused some apprehension. Its one of the recommendations in the report on the 2016 contamination of Havelock Norths water supply with sheep excrement, which hospitalised 45 people and made 5000 ill with gastroenteritis. It is also believed to have been a factor in three deaths, and some locals are still suffering complications from their illness.

The subsequent inquiry, which reported last month, provided reassurance to Aucklanders and Wellingtonians, whose water is already treated, that whats coming out of their taps wont make them sick. But it found more than 700,000 people in other districts receive a water supply whose safety simply cant be assured. The report was unsparing. Many local authorities had done a woeful job of maintaining infrastructure, and they and health officials had a patchy record of monitoring drinking-water quality.

The verdict that management of the systems that deliver our tap water has become so incoherent must rattle public confidence in local government. Councils reflex defence is that theyre too short of money to maintain expensive infrastructure. But that alone should be the starting point for what they fear most: a root-and-branch reappraisal of local government.

If maintaining basic infrastructure is beyond councils, its time to reconsider the divisions between central and local government. These have developed over many decades, piecemeal and often driven by political convenience, and the distinctions are often arbitrary and contradictory. Critics have long accused local and regional politicians of grandiose mission-creep, at the expense of the basics, water and sewerage being the most worryingly neglected.

That political turf war will take years to resolve. Local politicians defensiveness is matched by central politicians reluctance to make thorny and expensive regional problems their own.

In the meantime, chlorination seems the best way to prevent further public-health crises. Universal treatment was among the reports recommendations, along with standardisation of monitoring and national rather than local invigilation.

The Government has indicated it will impose...

06:41

Fluoride-related question slated for Parry Sound voters ballot "IndyWatch Feed Health"

Upgrades to the plant needed for fluoride to come back

PARRY SOUND The fluoride topic is back in Parry Sound.

This time its a question on the fall municipal election ballot.

Nearly two years ago, the Town of Parry Sound overturned its June 2015 resolution for improvements to the Tony Agnello Water Treatment Pant; the upgrades were necessary to continue fluoridating the municipal water supply.

When the original report came to council in 2015, upgrades to the plant were in the neighbourhood of $250,000. The Town had been fluoridating its water since the 1960s.

After a lengthy period of debate that included a campaign by a group of concerned citizens, Parry Sounders for Progressive Water Management, fluoridation of the towns water ended temporarily on March 18, 2016, under the condition that the question be posed on the 2018 municipal election ballot, asking Parry Sound ratepayers whether they want the town to continue to fluoridate their water.

A resolution was passed to put the question on the ballot during a January 2016 council meeting.

On Monday, Jan. 15, the town announced the date for the legislated public meeting that needs to be held prior to the passing of the bylaw.

The question slated for the ballot that falls under the Fluoridation Act, the question is already in the act, we dont get to figure out what (the question) is, they tell you what to ask. And that question will be answered and binding based on more than 50 per cent of the people who voted, depending on what the outcome is for that, said town clerk Jackie Boggs during the Jan. 16 council meeting.

The question is, Are you in favour of the discontinuance of the fluoridation of the public water supply of this municipality?

If it turns out that more than 50 per cent of voters are not in favour of the discontinuation of fluoride, there is a chance it could be put back into the water supply, but not before the necessary upgrades are made to the water treatment plant.

Peter Brown, town director of public works, said today the costs are likely significantly more than the original $250,000 estimate.

I suspect it will (cost) considerably more than that because the piping has sat stagnant for a couple of years and prices are always changing and going up as far as equipment goes. The cost of fluoride may have gone up, I dont know, Brown said. We havent really invested any time and energy into the consideration of bringing it back, because there was no indication that there was. Fast forward to 2018 and we have an election coming up I guess were going to have to sta...

06:22

Indian aluminium industry reeling under increased production costs despite LME upswing "IndyWatch Feed Health"

Trapped in a pincer of rising coal prices and flooding of cheap imports, domestic aluminium industry needs government policy support to come out of this crisis.

During the last four years Indian aluminium producers have made investments of Rs 1.2 lakh crore to enhance total domestic capacity from 2 MTPA to 4.1 MTPA, with a total debt on the industry at Rs 70,000 crore. The installed domestic aluminium capacity in the country stands at 4.1 million tons/annum against the current domestic demand 3.3 million tonnes/annum implying that there is sufficient domestic capacity to cater 125% of Indias aluminium demand.

Yet, the distressing fact is that 50% of Indian Aluminium consumption is being met through imports mostly from China and Gulf. What is even more revealing, and damaging to the cause of Make in India Aluminium, is the fact that 50% of these imports constitutes of scrap which attracts lesser duties. This clearly is crippling the domestic aluminium industry.

The relief that the ailing Indian Aluminium Industry was supposed to get from the upswing in global aluminium prices (LME) has been marred by increasing production costs over the past few quarters in FY 17-18. Despite the LME prices swinging on a record high in this current period, the domestic industry continues to reel under increasing input costs.

In the past couple of years, the production costs of the metal has significantly increased due imposition of various cess and increased duties, along with substantially increased input costs and escalated prices of critical raw materials like Coal, Alumina, CP Coke, Caustic Soda etc. with associated logistic costs. These have adversely impacted primary aluminium making costs, thereby depriving the domestic producers to capitalise on the favourable market opportunity.

The increase in input costs by $730/MT completely offsets the increase in aluminium LME price ($251/MT)

...
Particulars Previous Current Sp. Consumption/ MT of Aluminium Impact on Aluminium COP  ($/ MT)

Cess on Coal1

(introduced in 2010)

Rs 50/ MT...

04:42

Walnuts exhibit chemopreventive effects regarding the risk for colon cancer development by inducing expression of genes involved in detoxification. "IndyWatch Feed Health"

PMID:  Nutr Res. 2017 Nov ;47:72-80. Epub 2017 Sep 18. PMID: 29241580 Abstract Title:  In vitro-fermented raw and roasted walnuts induce expression of CAT and GSTT2 genes, growth inhibition, and apoptosis in LT97 colon adenoma cells. Abstract:  Walnuts are rich in bioactive compounds such as polyunsaturated fatty acids, polyphenols, and dietary fiber. Therefore, the consumption of walnuts can contribute to a healthy diet and may reduce the risk for colon cancer. Heat treatment like roasting may change the chemical composition of walnuts and therefore their chemopreventive properties. Therefore, the hypothesis of the present study is that different roasting conditions (RCs) alter the chemopreventive effects of walnuts. Thus, the aim of the present study was to investigate whether different RCs (RC1=139.7C/25 min, RC2=154.5C/20 min, and RC3=185.5C/25 min) alter the chemopreventive effects of walnuts. Raw and roasted walnuts were subjected to in vitro digestion and fermentation. After treatment of LT97 colon adenoma cells with fermentation supernatants (FSs), expression of CAT, SOD2, GPx1, GSTP1, and GSTT2 genes as well as cell growth and apoptosis was examined. In comparison to the fermentation blank control, walnut FS particularly increased mRNA levels of CAT 1.7-fold and GSTT2 3.1-fold, whereas GPx1 levels were significantly decreased 0.6-fold. Walnut FS decreased growth of adenoma cells in a time- and dose-dependent manner. In particular, higher concentrations of walnut FS (5%) significantly increased the number of early apoptotic cells 2.0-fold and induced caspase-3 activity 6.8-fold compared with the blank control. The roasting process had no direct impact on the observed effects. In sum, our results indicate that walnuts exhibit chemopreventive effects regarding the risk for colon cancer development by inducing expression of genes involved in detoxification (CAT, GSTT2) and by inducing growth inhibition and apoptosis in colon adenoma cells unaffected by moderate roasting.

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04:21

Walnut leaf extract exert protective effects against diabetic retinopathy. "IndyWatch Feed Health"

PMID:  Iran J Basic Med Sci. 2017 Nov ;20(11):1275-1281. PMID: 29299206 Abstract Title:  Therapeutic potential of Juglans regia L. leaf extract against diabetic retinopathy in rat. Abstract:  Objectives: Oxidative stress has a pivotal role in the pathogenesis of diabetic retinopathy (DR). Juglans regia L. (JRL) leaf extract has hypoglycemic and antioxidative properties. This study aimed to determine the ameliorative effects of JRL against diabetic retinopathy.Materials and Methods: The DR rat model was generated by injection of streptozotocin (STZ). A subset of the diabetic rats received JRL or metformin after the onset of hyperglycemia. Histopathology and immunohistochemistry of apoptotic and inflammatory factors were assessed along with biochemical assessments of lipid peroxidation and antioxidant status.Results: Lipid peroxidation level and catalase activity significantly improved after JRL consumption (P

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04:05

Consumption of nuts was associated with a 13% to 19% lower risk of total cardiovascular disease and 15% to 23% lower risk of coronary heart disease. "IndyWatch Feed Health"

PMID:  J Am Coll Cardiol. 2017 Nov 14 ;70(20):2519-2532. PMID: 29145952 Abstract Title:  Nut Consumption and Risk of Cardiovascular Disease. Abstract:  BACKGROUND: The associations between specific types of nuts, specifically peanuts and walnuts, and cardiovascular disease remain unclear.OBJECTIVES: The authors sought to analyze the associations between the intake of total and specific types of nuts and cardiovascular disease, coronary heart disease, and stroke risk.METHODS: The authors included 76,364 women from the Nurses' Health Study (1980 to 2012), 92,946 women from the Nurses' Health Study II (1991 to 2013), and 41,526 men from the Health Professionals Follow-Up Study (1986 to 2012) who were free of cancer, heart disease, and stroke at baseline. Nut consumption was assessed using food frequency questionnaires at baseline and was updated every 4 years.RESULTS: During 5,063,439 person-years of follow-up, the authors documented 14,136 incident cardiovascular disease cases, including 8,390 coronary heart disease cases and 5,910 stroke cases. Total nut consumption was inversely associated with total cardiovascular disease and coronary heart disease after adjustment for cardiovascular risk factors. The pooled multivariable hazard ratios for cardiovascular disease and coronary heart disease among participants who consumed 1 serving of nuts (28 g) 5 or more times per week, compared with the reference category (never or almost never), were 0.86 (95% confidence interval: 0.79 to 0.93; p for trend = 0.0002) and 0.80 (95% confidence interval: 0.72 to 0.89; p for trend 

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03:55

Melatonin inhibits the proliferation of breast cancer cells induced by bisphenol A. "IndyWatch Feed Health"

PMID:  Thorac Cancer. 2018 Jan 13. Epub 2018 Jan 13. PMID: 29330934 Abstract Title:  Melatonin inhibits the proliferation of breast cancer cells induced by bisphenol A via targeting estrogen receptor-related pathways. Abstract:  BACKGROUND: Background: BisphenolA (BPA) is an estrogen-like chemical widely contained in daily supplies. There is evidence that environmental exposure to BPA could contribute to the development of hormone-related cancers. As is reported in numerous studies, melatonin, an endogenous hormone secreted by the pineal gland, could markedly inhibit estrogen-induced proliferation of breast cancer (BC) cells. In this study, we intended to reveal the effects of melatonin on BPA-induced proliferation of estrogen receptor-positive BC cells.METHODS: Methods: We used methyl thiazolyl tetrazolium, luciferase reporter gene and western blotting assays to testify the effect of melatonin on BPA-mediated proliferation of MCF-7 and T47D cells.RESULTS: Methyl thiazolyl tetrazolium and colony formation assays showed that melatonin could significantly abolish BPA-elevated cell proliferation. Meanwhile, BPA-upregulated phosphorylation of ERK and AKT was decreased by melatonin treatment. Mechanistically, we found that BPA was capable of upregulating the protein levels of steroid receptor coactivators (SRC-1, SRC-3), as well as promoting the estrogen response element activity. However, the addition of melatonin could remarkably block the elevation of steroid receptor coactivators expression and estrogen response element activity triggered by BPA.CONCLUSION: Conclusions: Therefore, these results demonstrated that melatonin could abrogate BPA-induced proliferation of BC cells. Therapeutically, melatonin could be regarded as a potential medication for BPA-associated BC.

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02:46

Folic acid significantly enhanced the efficacy of curcumin in down-regulating various survival signals induced by paclitaxel in cervical cancer. "IndyWatch Feed Health"

PMID:  Oncotarget. 2017 Dec 8 ;8(64):107374-107389. Epub 2017 Nov 10. PMID: 29296172 Abstract Title:  Folic acid conjugation improves the bioavailability and chemosensitizing efficacy of curcumin-encapsulated PLGA-PEG nanoparticles towards paclitaxel chemotherapy. Abstract:  Nanoencapsulation has emerged as a novel strategy to enhance the pharmacokinetic and therapeutic potential of conventional drugs. Recent studies from our lab have established the efficacy of curcumin in sensitizing cervical cancer cells and breast cancer cells towards paclitaxel and 5-FU chemotherapy respectively. Factors that hinder the clinical use of curcumin as a sensitizer or therapeutic agent include its poor bioavailability and retention time. Earlier reports of improvement in bioavailability and retention of drugs upon nanoencapsulation have motivated us in developing various nanoformulations of curcumin, which were found to exhibit significant enhancement in bioavailability and retention time as assessed by our previous in vitro studies. Among the various formulations tested, curcumin-entrapped in PLGA-PEG nanoparticles conjugated to folic acid (PPF-curcumin) displayed maximum cell death. In the present study, we have demonstrated the efficacy of this formulation in augmenting the bioavailability and retention time of curcumin, in vivo, in Swiss albino mice. Further, the acute and chronic toxicity studies proved that the formulation is pharmacologically safe. We have also evaluated its potential in chemosensitizing cervical cancer cells to paclitaxel and have verified the results using cervical cancer xenograft model in NOD-SCID mice. Folic acid conjugation significantly enhanced the efficacy of curcumin in down-regulating various survival signals induced by paclitaxel in cervical cancer cells and have considerably improved its potential in inhibiting the tumor growth of cervical cancer xenografts. The non-toxic nature coupled with improved chemosensitization potential makes PPF-curcumin a promising candidate formulation for clinical trials.

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02:23

Simon Meehan 15 from Ireland wins top science prize for blackberry antibiotic that fights resistant bacteria "IndyWatch Feed Health"

Irish teen wins top science prize for blackberry antibiotic that fights resistant bacteria
By Erin Elizabeth - January 17, 2018


Simon Meehan, 15 years old, of Coliste Choilm, Ireland recently won first place in the 54th BT Young Scientist & Technology Exhibition after discovering that chemicals found within blackberries could form antibiotics1 capable of killing Staphylococcus aureus (MRSA) a virus well known for being resistant to antibiotics.
And get this: he says his herbalist grandfather was the inspiration that kept him going (he even kept a framed picture next to him while we worked)!
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The wise youngster said, I feel, without disrespecting the scientific community too much, that there should be some conclusions from this. We are over-thinking science in too many ways.2
We total...

02:20

These findings provide evidence of the protective role of dietary folate intake on head and neck cancer risk. "IndyWatch Feed Health"

PMID:  Br J Cancer. 2017 Nov 21. Epub 2017 Nov 21. PMID: 29161239 Abstract Title:  The impact of folate intake on the risk of head and neck cancer in the prostate, lung, colorectal, and ovarian cancer screening trial (PLCO) cohort. Abstract:  BACKGROUND: Although low levels of folate leads to disturbances in DNA replication, DNA methylation and DNA repair, the association between dietary folate intake and head and neck cancer (HNC) risk remains unclear.METHODS: We evaluated the association between folate intake and HNC risk using prospective cohort data from the Prostate, Lung, Colorectal, and Ovarian (PLCO) cancer screening trial. This study included 101700 participants and 186 cases with confirmed incident HNC. The median follow-up was 12.5 years. We estimated hazard ratios (HRs) and the corresponding 95% confidence intervals (CIs) using Cox proportional hazard model including age, sex, body mass index, education, race, tobacco smoking, alcoholdrinking and total fruit and vegetable intake.RESULTS: Higher intake of food folate and fortified folic acid in foods was associated with a decreasing HNC risk in a dose-response manner. The HRs of highest vs the lowest quartile of intake were 0.35 (95%CI: 0.18-0.67) for food folate, and 0.49 (95%CI: 0.30-0.82) for fortified folic acid. Intakes of total folate, natural folate and supplemental folic acid were not associated with the risk of HNC and its subsites. We did not detect any interaction between smoking, drinking and food folate intake on HNC risk.CONCLUSIONS: These findings provide evidence of the protective role of dietary folate intake on HNC risk.British Journal of Cancer advance online publication, 21 November 2017; doi:10.1038/bjc.2017.383 www.bjcancer.com.

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01:28

The present review provides a comprehensive insight of pharmacological and therapeutic potential of beta-caryophyllene. "IndyWatch Feed Health"

PMID:  Curr Pharm Des. 2016 ;22(21):3237-64. PMID: 26965491 Abstract Title:  Polypharmacological Properties and Therapeutic Potential of-Caryophyllene: A Dietary Phytocannabinoid of Pharmaceutical Promise. Abstract:  BACKGROUND: -Caryophyllene (BCP) is a natural bicyclic sesquiterpene abundantly found in essential oils from various spices, fruits and medicinal as well as ornamental plants. It is approved by United States Food and Drug Administration and European agencies as food additive, taste enhancer and flavoring agent and termed as a phytocannabinoid.METHODS: All the available literature on BCP and its synonyms were collected through different literature databases.RESULTS: BCP was found to elicit a full agonist action on cannabinoid type 2 (CB2) receptors, a G-protein coupled receptor representing important therapeutic target in several diseases. Activation of CB2 receptors notably appeared devoid of psychotropic adverse effect of cannabinoids contrary to the CB1 receptors. In addition, it activates peroxisome proliferated activator receptors (PPARs) isoforms; PPAR-&- and inhibits pathways triggered by the activation of toll like receptor complex; CD14/TLR4/MD2, reduce immuneinflammatory processes and exhibit synergy with -opioid receptor dependent pathways. Additionally, it found as potent antagonist of homomeric nicotinic acetylcholine receptors (7-nAChRs) and devoid of effects mediated by serotonergic and GABAergic receptors. It also modulates numerous molecular targets by altering their gene expression, signaling pathways or through direct interaction. Various pharmacological activities such as cardioprotective, hepatoprotective, gastroprotective, neuroprotective, nephroprotective, antioxidant, anti-inflammatory, antimicrobial and immune-modulator have been reported in experimental studies. It has shown potent therapeutic promise in neuropathic pain, neurodegenerative and metabolic diseases.CONCLUSION: The present review provides a comprehensive insight of pharmacological and therapeutic potential of BCP, its molecular mechanism and signaling pathways in different pathological conditions. The review also examines the possibility of its further development as a novel candidate for various pathologies considering the polypharmacological and multifaceted therapeutic properties potential along with favorable oral bioavailability, lipophilicity and physicochemical properties.

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01:20

Marijuana Advisor to Sessions Wants to Drug Test Everyone "IndyWatch Feed Health"

Marijuana Advisor to Sessions Wants to Drug Test Everyone

By Heather CallaghanEditor

We want [drug screens] to be routine in all medicine

Its bad enough in 2018 that the war on drugs still exists in the deluded minds of government higher-ups, just as some states begin to legalize recreational marijuana. And just as they do, Attorney General Jeff Sessions dropped the bomb that the Federal Government ended its leniency toward states rights for medical marijuanaThus, we devolve as a nation.

But the biggest blow to Americans was when Sessions DEA, although going after marijuana as a dangerous substance in essence gave a Pharma opioid maker the rights to a partial national monopoly on synthetic THC!

Whats worse, it looks like the War on Drugs has just collided with Mad Medicine.

...

01:00

Dr Ron Unfiltered Uncensored Dr Omalu "IndyWatch Feed Health"

Dr Ronand Dr Dan interview with the well known Dr Omalu and his knowledge of concussions.Drs Ron and Dan are honored to have the world famous Dr Omalu (the concussion doctor) as a guest. He was portrayed by Will Smith in the movie "Concussion" He is joing us from California to give us the latest advances in CTE and concussions. His recent book "Truth Doesn't Have a Side" is a must read for all parents, grandparents and care givers.

00:47

Gardasil killed Colton Berrett? The evidence does not support this claim "IndyWatch Feed Health"

The Skeptical Raptor, stalking pseudoscience in the internet jungle.

As I mentioned in a previous article, reading articles about vaccines leads to many tragic and heartfelt stories. But as a scientist, I have to separate the emotional aspects of a story from the science-based evidence. This post is particularly tough because this story is so devastating, that I wanted to ignore it (and have

Skeptical Raptor

00:46

Silymarin in high dose is a good choice for improvement of liver biochemical profile and QoL in chronic hepatitis C virus cirrhotic patients. "IndyWatch Feed Health"

PMID:  J Interferon Cytokine Res. 2017 Nov ;37(11):480-487. PMID: 29135373 Abstract Title:  High Dose of Silymarin in Patients with Decompensated Liver Disease: A Randomized Controlled Trial. Abstract:  Hepatitis C virus (HCV) is a major public health problem being the most common cause of chronic liver disease in Egypt. HCV-induced decompensated liver cirrhosis patients have a median survival of 2 years even with currently used new treatments. Silymarin is the most commonly used herbal product in chronic liver disease for its anti-inflammatory, antiviral, antioxidant, and antifibrotic effects. The aim of this study was to assess the effects of silymarin in high dose on the clinical and biochemical status of chronic HCV-associated decompensated liver cirrhosis. The study was conducted on 62 chronic HCV-decompensated cirrhotic patients. Patients were randomized according to treatment plans: group A, included 31 patients who received silymarin in dose of 1,050mg/day, and group B, included 31 patients who received silymarin in dose of 420mg/day. Patients were subjected to baseline history taking, laboratory evaluation, abdominal ultrasound, Child scoring, and quality-of-life (QoL) questionnaire. Follow-up was done every 2 weeks for 12 weeks. Silymarin in high dose had an effect on reducing alanine transaminase, aspartate aminotransferase levels (P0.01), as well as improving albumin (P=0.04), bilirubin (P=0.02), and international normalized ratio (P=0.03), thus resulted in improvement in Child score (P=0.048), however, regular silymarin regimen (420mg/day) failed to achieve the previous biochemical changes. High-dose regimen of silymarin also had a positive impact on improving QoL. No serious adverse events were reported. Silymarin in high dose is a good choice for improvement of liver biochemical profile and QoL in chronic HCV cirrhotic patients.

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00:34

Silibinin is a good sensitizing agent for rhTRAIL-resistant Triple-negative breast cancer. "IndyWatch Feed Health"

PMID:  Anticancer Res. 2017 12 ;37(12):6593-6599. PMID: 29187434 Abstract Title:  Sensitization of rhTRAIL-resistant Triple-negative Breast Carcinoma Through Silibinin Co-Treatment. Abstract:  BACKGROUND/AIM: Triple-negative breast cancer (TNBC) is the most fatal form of breast cancer due to the shortcomings of therapies. However, recombinant human tumor necrosis factor-related apoptosis-inducing ligand (rhTRAIL) is a promising anticancer therapeutic that possesses the capability to promote the induction of apoptosis in cancer cells, but some TNBCs are resistant to rhTRAIL's pro-apoptotic effects. Therefore, a combinatorial treatment approach with silibinin and rhTRAIL was considered in order to sensitize rhTRAIL-resistant TNBCs.MATERIALS AND METHODS: The co-treatment of rhTRAIL and silibinin's impact on apoptosis induction in rhTRAIL-resistant TNBC BT-20 and HCC1937 cells was inspected via application of Annexin V/PI assays and western blot analysis.RESULTS: Silibinin possessed the ability to sensitize the examined rhTRAIL-resistant TNBC cells to rhTRAIL-induced apoptosis through the up-regulation of death receptors 4 and 5 and the down-regulation of survivin transcriptionally.CONCLUSION: Silibinin is a good sensitizing agent for rhTRAIL-resistant TNBCs.

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00:22

Ajwa date extract afforded significant protection against carbon tetrachloride-induced hepatocellular injury. "IndyWatch Feed Health"

PMID:  Pak J Pharm Sci. 2017 Nov ;30(6):2183-2191. PMID: 29175788 Abstract Title:  Abrogation of carbon tetrachloride-induced hepatotoxicity in Sprague-Dawley rats by Ajwa date fruit extract through ameliorating oxidative stress and apoptosis. Abstract:  Ajwa, a variety of date palme Phoenix dactylifera L., has long been used and considered as one of the most popular fruits in the North Africa and Middle East region. For Muslims this fruit is of religious importance and is mentioned several times in Quran. Besides being a part of the Arabian essential diet, dates have been used traditionally for number of complications. This study aimed to evaluate the possible potential of Ajwa date extract to guard against carbon tetrachloride (CCL4)-induced liver damage in rats. Adult male Sprague-Dawley rats were given Ajwa date extract and silymarin (a standard reference drug) at doses of 300&50mg/kg, p.o., respectively for 2 weeks before CCl4 (2 ml/kg, s. c., twice weekly for 8 consecutive weeks), and concomitantly administered with CCl4 for 8 consecutive weeks. Like silymarin, Ajwa date extract produced significant decrease in serum levels of alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), total cholesterol, triglycerides (TG) and LDL-cholesterol as well as lipid peroxides measured as malondialdehyde (MDA), hydroxyproline and caspase-3 contents of liver tissue with marked increase in serum albumin, HDL-cholesterol and reduced glutathione (GSH) content as well as enzyme activities of super oxide dismutase (SOD), catalase (CAT) and glutathione-S-transferase (GST). In conclusion, Ajwa date extract afforded significant protection against CCl4-induced hepatocellular injury; an effect that could be attributed to its antioxidant, antiapoptotic and antifibrotic activities.

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00:05

Silymarin can significantly reduce anxiety and depression-like symptoms, and neuroinflammation after mild traumatic brain injury. "IndyWatch Feed Health"

PMID:  Toxicol Appl Pharmacol. 2018 Jan 1 ;338:159-173. Epub 2017 Nov 22. PMID: 29175455 Abstract Title:  Anxiolytic- and antidepressant-like effects of Silymarin compared to diazepam and fluoxetine in a mouse model of mild traumatic brain injury. Abstract:  Clinical and experimental studies have shown that mild traumatic brain injury (mTBI) is associated with increased anxiety- and depression-related behaviors and inflammation in the brain. Unfortunately, there are no specific therapies for long-term behavioral consequences of mTBI. This study set out to determine whether silymarin treatment compared to diazepam (DZP) and fluoxetine (FLX) can reduce neuroinflammation, anxiety- and depression-like behaviors after mTBI induction in mice. We used open field, elevated plus maze, light-dark box, zero maze, sucrose preference, forced swim, and tail suspension tests to assess anxiety and depression-like behaviors in mTBI-induced mice. The levels of tumor necrosis factor (TNF)- protein, a marker of inflammation, in the prefrontal cortex and hippocampus was also measured. This study identified that the long-term treatment with DZP, FLX or SIL results in decreased anxiety and depression-like behaviors in mTBI-induced mice. The results also showed that these drugs reducedTNF- levels in the prefrontal cortex and hippocampus. In addition, there were no significant differences between the effects of SIL and DZP or SIL and FLX on behavioral and cytokine levels in mTBI-induced mice. Our findings support the idea that mTBI could be a risk factor for anxiety- and depression-related disorders and neuroinflammation in the brain. Taken together, this study demonstrates that DZP, FLX or SIL can significantly reduce anxiety- and depression-like symptoms, and neuroinflammation after mTBI induction in mice.

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Wednesday, 17 January

23:39

Therapeutic potential of silymarin in chronic unpredictable mild stress induced depressive-like behaviour. "IndyWatch Feed Health"

PMID:  J Psychopharmacol. 2017 Dec 1:269881117742666. Epub 2017 Dec 1. PMID: 29215318 Abstract Title:  Therapeutic potential of silymarin in chronic unpredictable mild stress induced depressive-like behavior in mice. Abstract:  Silymarin, a plant-derived polyphenolic flavonoid of Silybum marianum, elicited significant antidepressant-like activity in an acute restraint stress model of depression. It improved monoamines, mainly 5-hydroxytryptamine (5-HT) levels in the cortex, dopamine (DA) and norepinephrine (NE) in the cerebellum in mice. The present study was undertaken to explore the antidepressant potential of silymarin in chronic unpredictable mild stress (CUMS) induced depressive-like behavior in mice, and to find out its probable mechanism(s) of action, mainly neurogenesis, neuroinflammation, and/or oxidative stress. The mice were subjected to CUMS for 28 days (4 weeks) and administered with silymarin (100 mg/kg and 200 mg/kg), or fluoxetine or vehicle from days 8 to 28 (3 weeks simultaneously). Animals were evaluated for behavioral changes, such as anhedonia by sucrose preference test, behavioral despair by forced swim test, and exploratory behaviors by an open field test. In addition, neurobiochemical alterations, mainly monoamines, 5-HT, NE, DA, neurotrophic factor BDNF, and cytokines, IL-6, TNF-, oxidant-antioxidant parameters by determining the malondialdehyde formation (an index of lipid peroxidation process), superoxide dismutase (SOD) and catalase (CAT) activity in hippocampus and cerebral cortex along with serum corticosterone were investigated. Our findings reveal that mice subjected to CUMS exhibited lower sucrose preference, increase immobility time without affecting general locomotion of the animals, and reduce BDNF, 5-HT, NE, and DA level, increased serum corticosterone, IL-6 and TNF- along with an oxidant-antioxidant imbalance in the hippocampus and cerebral cortex. Silymarin significantly reversed the CUMS-induced changes in the hippocampus and cerebral cortex in mice. Thus, the possible mechanism involved in the antidepressant-like activity of silymarin is correlated to the alleviation of monoaminergic, neurogenesis (enhancing 5-HT, NE, and BDNF levels), and attenuation of inflammatory cytokines system and oxidative stress by modulation of corticosterone response, restoration of antioxidant defense system in cerebral cortex and hippocampus.

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23:31

Silymarin ameliorates diabetes-induced proangiogenic response in brain endothelial cells. "IndyWatch Feed Health"

PMID:  J Diabetes Res. 2017 ;2017:2537216. Epub 2017 Oct 25. PMID: 29209632 Abstract Title:  Silymarin Ameliorates Diabetes-Induced Proangiogenic Response in Brain Endothelial Cells through a GSK-3 Inhibition-Induced Reduction of VEGF Release. Abstract:  Diabetes mellitus (DM) is a major risk factor for cardiovascular disease. Additionally, it was found to induce a dysfunctional angiogenic response in the brain that was attributed to oxidative stress. Milk thistle seed extract (silymarin) has potent antioxidant properties, though its potential use in ameliorating diabetes-induced aberrant brain angiogenesis is unknown. Glycogen synthase kinase-3 is a regulator of angiogenesis that is upregulated by diabetes. Its involvement in diabetes-induced angiogenesis is unknown. To evaluate the potential of silymarin to ameliorate diabetes-induced aberrant angiogenesis, human brain endothelial cells (HBEC-5i) were treated with 50g/mL advancedglycation end (AGE) products in the presence or absence of silymarin (50, 100M). The angiogenic potential of HBEC-5i was evaluated in terms of migration and in vitro tube formation capacities. The involvement of GSK-3 was also evaluated. AGE significantly increased the migration and tube formation rates of HBEC-5i by about onefold (p = 0.0001). Silymarin reduced AGE-induced migration in a dose-dependent manner where 50M reduced migration by about 50%, whereas the 100M completely inhibited AGE-induced migration. Similarly, silymarin 50g/mL blunted AGE-induced tube formation (p = 0.001). This effect was mediated through a GSK-3-dependent inhibition of VEGF release. In conclusion, silymarin inhibits AGE-induced aberrant angiogenesis in a GSK-3-mediated inhibition of VEGF release.

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22:55

Chairman of Israel Medical Association and World Medical Association Opposes Mandatory Flu Vaccines for Doctors "IndyWatch Feed Health"

Prof. Leonid Eidelman

Prof. Leonid Eidelman is chairman of the Israel Medical Association and in 2017 was chosen as the next president of the World Medical Association. He opposes mandatory flu vaccinations for doctors. Image source.

by Brian Shilhavy
Editor, Health Impact News

In order to get a perspective on sane and rational vaccine policy, we must again turn away from the U.S. corporate media and their primary advertising sponsors, the pharmaceutical industry.

The flu vaccine is, by far, the most prosperous vaccine produced and sold in the U.S., with over 300 million doses produced annually. It is also the leading vaccine, by far, injuring and killing people as evidenced by the quarterly Department of Justice (DOJ) reports of vaccine injury and death compensations by the Vaccine Court.

As far as we know, Health Impact News is still the only news source publishing settled cases for vaccine injury and death compensations in the national Vaccine Court.

In the U.S., one cannot sue a pharmaceutical company for injuries or deaths related to vaccines.

By simply reading the U.S. corporate mainstream media one is led to believe that all doctors and medical personnel support mass flu vaccination, and believe all medical staff should be forced to receive the flu vaccine every year.

But such is not the case. As we have reported over the past several years, many doctors and nurses nationwide oppose mandatory flu vaccination for medical personnel. There are several lawsuits by individuals and unions nationwide fighting loss of employment due to refusing a flu vaccine.

Not only are there questions regarding the efficacy of the flu vaccine that would mean un-vaccinated medical personnel present no greater danger to patients than those vaccinated for influenza, there are also serious civil rights issues involve...

22:43

Combined iron-chelation and silymarin therapy was effective for improving the iron-burden status in patients with -thalassemia major. "IndyWatch Feed Health"

PMID:  Phytother Res. 2017 Dec 13. Epub 2017 Dec 13. PMID: 29235162 Abstract Title:  Iron-chelating effect of silymarin in patients with-thalassemia major: A crossover randomised control trial. Abstract:  This study aimed to determine the potential iron-chelating effects of silymarin in patients with-thalassemia major receiving standard iron-chelation therapy. We evaluated whether addition of silymarin to standard iron-chelation therapy could improve iron burden markers and liver and cardiac function in these patients, via a placebo-controlled, crossover clinical study. Silymarin (140 mg) orplacebo were administered thrice daily to all patients (n = 82) for 12 weeks, and after a 2-week washout period, patients were crossed over to the other groups. Silymarin efficacy was assessed by measuring serum iron level, ferritin level, total iron-binding capacity and liver and cardiac function on magnetic resonance imaging. Silymarin treatment resulted in a negative change in the serum iron and ferritin levels and a positive change in the total iron-binding capacity levels (treatment effect, p 

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22:42

Appellate court reverses injunction in Inhance Technologies trade secret ruling "IndyWatch Feed Health"

HOUSTON The Texas 1st District Court of Appeals has reversed a permanent injunction and remanded a lower courts ruling of injunctive relief for further proceedings in a trade secrets lawsuit.

The court, however, upheld the district court ruling Jan. 9 awarding Inhance Technologies LLC $4 million in reasonable royalty damages and $10,500 in lost profits.

Justice Jane Bland wrote the opinion with justices Laura Carter Higley and Harvey G. Brown concurring.

The competing company, TMRJ Holdings, appealed the decision from the 269th District Court of Harrison County. On appeal, TMRJ argued the trial court erred in awarding both damages and permanent injunctive relief, maintaining that the two remedies are duplicative and to award both violates the one-satisfaction rule.

TMRJ also argued that the trial courts injunction is overly vague, failing to define the conduct it bans.

According to the opinion, Inhance developed a proprietary method for developing fluorine gas that reduces the cost of its surface fluorination process. This enabled the company to grow its business and offer lower prices than its competitors.

Founders Bill Brown and Monty Ballard invested 30 years of research and development in the process for producing fluorine gas in-house, the opinion states.

Two executives Paul Banks and David Molthen left Inhance and formed their own company.

From 2012 to mid-2013, Banks and Molthen developed a business plan to form TMRJ and were considering facilities close to an existing Inhance plant that served some of Inhances largest customers.

Inhance fired Molthen in June 2013. Banks left the company later that month and the pair quickly developed their first fluorine-gas production cell, the opinion states.

After three months of business, Inhance suspected Banks and Molthen were using their knowledge of the company and its processes without permission, the opinion states. In July 2015, Inhance sued TMRJ, Banks and Molthen, alleging trade-secret misappropriation, breach of contract, and other claims, and seeking temporary and permanent injunctive relief, the opinion states. Inhance also received a temporary restraining order against TMRJ, preventing the company from using Inhances processes, specifications, designs and pricing.

In October 2015, the trial court entered a temporary injunction against TMRJ, Banks and Molthen, preventing them from using or disclosing Inhances proprietary processes and equipment, the opinion states.

Inhance maintains that de...

22:36

How to Tell If Coconut Oil Is Bad: 4 Signs of Expired Coconut Oil "IndyWatch Feed Health"

Coconut oil is a tasty edible oil that has a long shelf life and contains many health benefits. Because it has a high content of fatty acids, coconut oil doesnt go bad very quickly. In fact, its the high levels of lauric acid in coconut oil that give it its many beneficial medicinal properties. However, if kept for a long time, coconut oil can go rancid and start smelling bad. You might notice that when coconut oil goes off, its color changes from white to a yellowish mass that may have spots of mold on it.

The shelf life of coconut oil depends a lot on the way it was produced and how it is stored. For example, pure virgin coconut oil (the kind thats great for your health) generally stays fresh longer than refined coconut oil. Coconut oil will have a best by date on the jar and this gives an indication of when you can expect the oil to go rancid. However, usually, the smell of coconut oil is a good indication if it has gone bad.

In this article, I am going to look at the 4 telltale signs of bad coconut oil. You will also find out if there is anything you can do to extend the shelf life of coconut oil. This is important to know especially if you are using or consuming coconut oil for its health benefits. I will also look briefly at the many health benefits of coconut oil for your skin, hair, and even helping to lose weight!

Types of Coconut Oil Refined vs. Unrefined

There are 2 types of coconut oil that you can use for cooking or on your skin refined or unrefined (virgin) coconut oil. Both refined and unrefined coconut oil have their own advantages and disadvantages.

Refined coconut oil is made by bleaching and purifying the coconut meat before drying it. The refined coconut oil (sometimes called copra oil) is then extracted to produce an oil with no flavor or odor. The benefit of refined coconut oil is that it has a smoke point of 450F (232C) which makes it better for frying with. However, much of the goodness is removed in the processing.

Virgin coconut oil is less processed and contains more beneficial properties than refined coconut oil. Depending on the method used, coconut meat is dried or processed fresh. From dried coconut meat, the oil is pressed out mechanically. To extract oil from fresh coconut meat that hasnt been dried, coconut milk is then mechanically squeezed out. It is then processed naturally to separate the oil. Both of these methods allow the coconut oil to retain its distinct coconut flavor and smell.

The Journal of Applied Sciences reported that virgin coconut oil (VCO) contains high levels of lauric acid which has antimicrobial properties. These fatty acids are useful...

22:26

Chairman of Israel Medical Association and World Medical Association Opposes Mandatory Flu Vaccines for Doctors "IndyWatch Feed Health"

Prof. Leonid Eidelman

Prof. Leonid Eidelman is chairman of the Israel Medical Association and in 2017 was chosen as the next president of the World Medical Association. He opposes mandatory flu vaccinations for doctors. Image source.

by Brian Shilhavy
Editor, Health Impact News

In order to get a perspective on sane and rational vaccine policy, we must again turn away from the U.S. corporate media and their primary advertising sponsors, the pharmaceutical industry.

The flu vaccine is, by far, the most prosperous vaccine produced and sold in the U.S., with over 300 million doses produced annually. It is also the leading vaccine, by far, injuring and killing people as evidenced by the quarterly Department of Justice (DOJ) reports of vaccine injury and death compensations by the Vaccine Court.

As far as we know, Health Impact News is still the only news source publishing settled cases for vaccine injury and death compensations in the national Vaccine Court.

In the U.S., one cannot sue a pharmaceutical company for injuries or deaths related to vaccines.

By simply reading the U.S. corporate mainstream media one is led to believe that all doctors and medical personnel support mass flu vaccination, and believe all medical staff should be forced to receive the flu vaccine every year.

But such is not the case. As we have reported over the past several years, many doctors and nurses nationwide oppose mandatory flu vaccination for medical personnel. There are several lawsuits by individuals and unions nationwide fighting loss of employment due to refusing a flu vaccine.

Not only are there questions regarding the efficacy of the flu vaccine that would mean un-vaccinated medical personnel present no greater danger to patients than those vaccinated for influenza, there are also serious civil rights issues involved a...

22:19

People Reveal Their Scars and How They Got Them in a Powerful Photo Project "IndyWatch Feed Health"

24-year-old, UK-based fashion and portrait photographer Sophie Mayanne is the artist behind the photography project called Behind the Scars. This project celebrates the tumbles and victories behind every scar by capturing them in a different light through a series of photos showcasing them as wonderful imperfections. Sophies vision is to reveal the uniqueness of every... View Article

The post People Reveal Their Scars and How They Got Them in a Powerful Photo Project appeared first on Healthy Holistic Living.

22:10

5 Polite Phrases That Will Disarm Rude People Instantly "IndyWatch Feed Health"

This article is shared with permission from our friends at Truth Theory. When someone is rude to you, it can be hard not to get upset. Your initial reaction is often to make a cutting retort. However, if you resist the temptation to lose self-control and get angry, you will be able to respond to... View Article

The post 5 Polite Phrases That Will Disarm Rude People Instantly appeared first on Healthy Holistic Living.

22:04

Rh Negative: Are There Aliens Among Us? "IndyWatch Feed Health"

Humans have not been around very long. Millions of years before we were even a speck in the eye of the universe, there was life roaming Earth as it spun around the Sun. Now, its hard to imagine any other life out there, but the chances of us not being alone in the universe is... View Article

The post Rh Negative: Are There Aliens Among Us? appeared first on Healthy Holistic Living.

22:03

Radioprotective effects of Silymarin on the sperm parameters of NMRI mice irradiated with -rays. "IndyWatch Feed Health"

PMID:  J Photochem Photobiol B. 2017 Dec 6 ;178:489-495. Epub 2017 Dec 6. PMID: 29232573 Abstract Title:  Radioprotective effects of Silymarin on the sperm parameters of NMRI mice irradiated with-rays. Abstract:  Free radicals and reactive oxygen species (ROS) are generated using various endogenous systems or from external sources such as exposure to different physiochemicals. Ionizing radiation damage to the cell can be caused by the direct or indirect effects of radiotherapy processes. Silymarin (SM), a flavanolignan compound, has been identified as a natural potent antioxidant with cytoprotection activities due to scavenging free radicals. The aim of the present study was to evaluate the radioprotective effect of SM on sperm parameters of mice induced by-rays. A total number of 40 adult, male NMRI mice were randomly divided into four equal groups. The control group was neither treated with SM nor irradiated by -rays. The second group was only irradiated with 2Gy of -rays. The third group was firstly treated with 50mg/kg of SM for 7 consecutive days, and one day later, last injections were irradiated by 2Gy of -rays. The fourth groups received only 50mg/kg of SM for 7 consecutive days. All the animals were treated intraperitoneally. Histopathological and morphometrical examinations were performed. The data were analyzed using ANOVA andTukey post hoc test. A value of p

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22:02

If You Experience Any of These 5 Signs You Are the Carrier of Your Family Karma "IndyWatch Feed Health"

Do you ever wonder what other traits you inherited from parents besides their DNA? Im sure you can pinpoint certain qualities, habits, and attributes in your character that you feel you acquired from either your mom or your dad. For example, you might associate your obsession with cleaning as a quality you picked up from... View Article

The post If You Experience Any of These 5 Signs You Are the Carrier of Your Family Karma appeared first on Healthy Holistic Living.

21:48

Islet autoimmunity may be increased by using hydrolyzed compared with nonhydrolyzed cow's milk-based infant formula. "IndyWatch Feed Health"

PMID:  Diabetes Care. 2017 03 ;40(3):398-404. Epub 2017 Jan 17. PMID: 28096222 Abstract Title:  First Infant Formula Type and Risk of Islet Autoimmunity in The Environmental Determinants of Diabetes in the Young (TEDDY) Study. Abstract:  OBJECTIVE: Studies on the introduction of infant formulas and its effect on the risk of islet autoimmunity and type 1 diabetes (T1D) have yielded inconsistent results. We investigated whether the introduction of formula based on hydrolyzed cow's milk as the first formula is associated with reduced islet autoimmunity risk in a large prospective cohort.RESEARCH DESIGN AND METHODS: The Environmental Determinants of Diabetes in the Young (TEDDY) study prospectively monitors 8,676 children at increased genetic risk for T1D. Autoantibodies to insulin, GAD65, and IA2 were measured regularly to define islet autoimmunity. Information on formula feeding was collected by questionnaires at 3 months of age.RESULTS: In survival analyses, after adjustment for family history with T1D, HLA genotype, sex, country, delivery mode, breast-feeding3 months, and seasonality of birth, we observed no significant association with islet autoimmunity in infants who received extensively hydrolyzed compared with nonhydrolyzed cow's milk-based formula as the first formula during the first 3 months (adjusted hazard ratio 1.38 [95% CI 0.95; 2.01]), and a significantly increased risk for extensively hydrolyzed formula introduced during the first 7 days (adjusted hazard ratio 1.57 [1.04; 2.38]). Using a partially hydrolyzed or other formula as the first formula, or no formula, was not associated with islet autoimmunity risk.CONCLUSIONS: These results add to the existing evidence that islet autoimmunity risk is not reduced, and may be increased, by using hydrolyzed compared with nonhydrolyzed cow's milk-based infant formula as the first formula in infants at increased genetic risk for T1D.

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21:46

Snacks fuel tooth decay even if you brush, says study "IndyWatch Feed Health"

Title of Study: Positive association between sugar consumption and dental decay prevalence independent of oral hygiene in pre-school children: a longitudinal prospective study,
Journal of Public Health, Dec 29, 2017

21:40

A polar extract of Curcuma longa protects cartilage homeostasis "IndyWatch Feed Health"

PMID:  Inflammopharmacology. 2018 Jan 8. Epub 2018 Jan 8. PMID: 29313174 Abstract Title:  Polar extract of Curcuma longa protects cartilage homeostasis: possible mechanism of action. Abstract:  BACKGROUND: Curcuma longa has been well documented for managing joint inflammation and pain. The present study investigated the effect of polar extract of C. longa (NR-INF-02) on cartilage homeostasis in human articular chondrocytes knee (NHAC-kn) cells to understand its plausible mechanism of action.METHODS: Dysregulation of cartilage homeostasis was induced by IL-1 and H2O2. Modulating effects of NR-INF-02 on degradation markers viz., chondrocyte apoptosis, senescence, cytokine, eicosanoids, and cartilage synthesis markers viz., glycosaminoglycans and type II collagen degradation was evaluated in human articular chondrocytes knee (NHAC-kn) cells. Further, the effect of NR-INF-02 on lipopolysaccharide (LPS)-induced expression of NF-kB in RAW264.7 macrophages was investigated.RESULTS: NR-INF-02 significantly attenuated IL-1-induced chondrocyte cytotoxicity, apoptosis and release of chondrocyte degradation markers such as IL-6, IL-8, COX-2, PGE2, TNF-, ICAM-1 in NHAC-kn cells. Also, NR-INF-02 protected IL-1-induced damage to synthesis markers such as glycosaminoglycans, type II collagen and further attenuated H2O2-induced chondrocyte senescence. In addition NR-INF-02 suppressed LPS-induced NF-kB expression in RAW264.7 cells.CONCLUSIONS: NR-INF-02 protects cartilage homeostasis by maintaining the balance between synthesis and degradation of cartilage matrix.

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21:23

Walden: Notice of Special Meeting on Fluoridation "IndyWatch Feed Health"

PLEASE TAKE NOTICE that the Village of Walden, Board of Trustees will hold a special meeting on Monday, January 22, 2018 on the Third Floor of the Municipal Building, One Municipal Square, Walden, NY at 11am.

AGENDA

Water Fluoridation Presentation NYS Department of Health

And any other business that may come before the Board

The Village of Walden will make every effort to assure that the meeting is accessible to persons with disabilities.  Anyone requiring special assistance and/or accommodations should contact the Village Clerk.

Tara Bliss, Village Clerk

*Original notice online at https://villageofwalden.org/1-22-18-special-meeting

21:12

Molecular hepatoprotective effects of lipoic acid against carbon tetrachloride-induced liver fibrosis in rats. "IndyWatch Feed Health"

PMID:  Hum Exp Toxicol. 2018 Feb ;37(2):142-154. Epub 2017 Feb 21. PMID: 29233029 Abstract Title:  Molecular hepatoprotective effects of lipoic acid against carbon tetrachloride-induced liver fibrosis in rats: Hepatoprotection at molecular level. Abstract:  BACKGROUND: Liver fibrosis is a noteworthy well-being issue that can prompt the progression of liver cirrhosis and hepatocellular carcinoma. Prominently, many antioxidants have been shown to have defensive impacts against liver fibrosis.AIM: Subsequently, in the present study, the viability of alpha-lipoic acid (-LA) in ensuring against carbon tetrachloride (CCl4)-actuated liver fibrosis and the mechanism(s) involved in this defensive impact were considered in rats.RESULTS: The present results uncovered that in the CCl4-treated group, the expression of antioxidant enzymes and matrix metalloproteinase-13 (MMP-13) messenger RNA (mRNA) was downregulated ( p

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21:06

FDA Declares All Homeopathic Drugs Illegal Threatening Remedies for Millions of Americans "IndyWatch Feed Health"

A blue homeopathic medicine container is open on an aluminum surface. Three white pills on it. Container blue. In the background is more blurred homeopathic medicine containers.

20:50

Colon Irrigation Audio Bite #15 "IndyWatch Feed Health"

When it comes to colon cleansing, people often ask if Dr. Sebi has spoke on colonics. Yes he has! Buckle your seat belt and hit the play button when you are ready. Dr. Sebi Says NO To Colon Irrigation Colonic irrigation is extremely unhealthy because it pushes water against your Continue reading

20:34

timing of nutritional supplements "IndyWatch Feed Health"

Friendly User's Guide for the Timing of Nutritional Supplements

  • 856 
  • January 17, 2018 95,841 views
  • Edition: English



Story at-a-glance
  • Fifty-two percent of American adults reported using nutritional supplements in 2012, a statistic that has remained stable since 1999. Americans spent $21 billion on nutritional supplements in 2015
  • While the use of multivitamins has decreased somewhat, use of vitamin D and omega-3 supplements have dramatically increased between 1999 and 2012
  • While dietary supplements are generally safe, when and how you take them such as with or without food, or before or after exercise can make a difference both in terms of safety and effectiveness
  • Since multivitamins contain an array of both water- and fat-soluble vitamins, its generally recommended you take half of your daily dose in the morning, with breakfast, and the other half with your main meal
  • Studies have shown that taking antioxidant supplements immediately prior to exercise has the curious effect of decreasing insulin sensitivity. It also hampers your bodys ability to defend itself against oxidative damage
30 Tips in 30 Days Designed to Help You Take Control of Your Health
This article is part of the 30 Day Resolution Guide series. Each day a new tip will be added designed to help you take control of your health. For a complete list of the tips click HERE
By Dr. Mercola
...

20:04

New Study Reveals Mushrooms Cure Depression by Doing the Exact Opposite of Anti-Depressants "IndyWatch Feed Health"

A recent study shows that psilocybin-assisted therapy mitigates depression by increasing emotional connectionthe exact opposite of anti-depressants.

revolutionary new study is once again revealing a natural approach to be far superior to big pharma solutionsthis time involving psilocybin, the active compound in magic mushrooms.

The study, published in the scientific journal Neuropharmacology, found that clinically depressed people had increased neural responses to fearful faces one day after a psilocybin-assisted therapy session, which positively predicted positive clinical outcomes.

SEE: Magic Mushrooms Could Hit A Reset Button On Depressed Brains

Psilocybin-assisted therapy might mitigate depression by increasing emotional connection, neuroscientist and study author Leor Roseman, a Ph.D. student at Imperial College London, explained to PsyPost.

This is almost the exact opposite of how standard ant...

20:01

Statistical Revelations Seem To Disprove Flu Mania "IndyWatch Feed Health"

When we fall ill in the winter season, we always refer to our sickness as, the flu. For most of us, weve accepted the fallacy in terminology as a simple way to tell our sister-in-law...

The post Statistical Revelations Seem To Disprove Flu Mania appeared first on Vaxxter.

19:37

Suggestive evidence supports the contention that breastfeeding reduces the risk of type 1 diabetes. "IndyWatch Feed Health"

PMID:  Diabetes Care. 2017 07 ;40(7):920-927. Epub 2017 May 9. PMID: 28487451 Abstract Title:  Infant Feeding and Risk of Type 1 Diabetes in Two Large Scandinavian Birth Cohorts. Abstract:  OBJECTIVE: Our aim was to study the relation between the duration of full and any breastfeeding and risk of type 1 diabetes.RESEARCH DESIGN AND METHODS: We included two population-based cohorts of children followed from birth (1996-2009) to 2014 (Denmark) or 2015 (Norway). We analyzed data from a total of 155,392 children participating in the Norwegian Mother and Child Cohort Study (MoBa) and the Danish National Birth Cohort (DNBC). Parents reported infant dietary practices when their child was 6 and 18 months old. The outcome was clinical type 1 diabetes, ascertained from nationwide childhood diabetes registries. Hazard ratios (HRs) were estimated using Cox regression.RESULTS: Type 1 diabetes was identified in 504 children during follow-up, and the incidence of type 1 diabetes per 100,000 person-years was 30.5 in the Norwegian cohort and 23.5 in the Danish cohort. Children who were never breastfed had a twofold increased risk of type 1 diabetes compared with those who were breastfed (HR 2.29 [95% CI 1.14-4.61] for no breastfeeding vs. any breastfeeding for12 months). Among those who were breastfed, however, the incidence of type 1 diabetes was independent of duration of both full breastfeeding (HR per month 0.99 [95% CI 0.97-1.01]) and any breastfeeding (0.97 [0.92-1.03]).CONCLUSIONS: Suggestive evidence supports the contention that breastfeeding reduces the risk of type 1 diabetes. Among those who were breastfed, however, no evidence indicated that prolonging full or any breastfeeding was associated with a reduced risk of type 1 diabetes.

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19:16

Did America Get Fat by Listening to Government Experts? "IndyWatch Feed Health"

By Richard Morrison

How much disease has been caused by the Food Pyramid?

A panel of government experts gets together and decides what is healthy to eat and what isnt. What could possibly go wrong?

Freethink Medias new video on the history of the Food Pyramid will make for surprising viewing for anyone who assumes official health and nutrition advice should be taken at face value.

Starting in the late 1980s, the office of the U.S. Surgeon General took the lead in waging the federal governments war on dietary fat. This led to years of recommendations and public information campaigns that, among other things, demonized animal protein sources (that often come along with a significant amount of fat) and steered Americans towards consumption of lots of low-fat carbohydrates insteadthe base of the pyramid. Many Americas will remember the 1990s as the golden age of carbs.

Now, of course, further research suggests that going down that path has actually made diet-rel...

19:04

MRI reveals increased tumorigenesis following high fat feeding in a mouse model of triple-negative breast cancer. "IndyWatch Feed Health"

PMID:  NMR Biomed. 2017 Oct ;30(10). Epub 2017 Jun 29. PMID: 28661075 Abstract Title:  MRI reveals increased tumorigenesis following high fat feeding in a mouse model of triple-negative breast cancer. Abstract:  High animal fat consumption is associated with an increase in triple-negative breast cancer (TNBC) risk. Based on previous MRI studies demonstrating the feasibility of detecting very early non-palpable mammary cancers in simian virus 40 large T antigen (SV40TAg) mice, we examined the effect of dietary fat fed from weaning to young adulthood in this model of TNBC. Virgin female C3(1)SV40TAg mice (n = 16) were weaned at 3-4 weeks of age and then fed either a low fat diet (LFD) (n = 8, 3.7 kcal/g; 17.2% kcal from vegetable oil) or a high animal fat diet (HAFD) (n = 8, 5.3 kcal/g; 60% kcal from lard). After 8 weeks on the diet (12 weeks of age), fast spin echo MR images of inguinal mammary glands were acquired at 9.4 T. Following in vivo MRI, mice were sacrificed and inguinal mammary glands were excised and formalin fixed for ex vivo MRI. 3D volume-rendered MR images were then correlated with mammary gland histology to assess the glandular parenchyma and tumor burden. Using invivo MRI, an average of 3.88  1.03 tumors were detected per HAFD-fed mouse compared with an average of 1.25  1.16 per LFD-fed mouse (p 

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17:48

Vitamin C with decitabine activates TET2 in leukemic cells and significantly improves overall survival in elderly patients with acute myeloid leukemia. "IndyWatch Feed Health"

PMID:  Leuk Res. 2018 Jan 2 ;66:1-7. Epub 2018 Jan 2. PMID: 29331774 Abstract Title:  The synergy of Vitamin C with decitabine activates TET2 in leukemic cells and significantly improves overall survival in elderly patients with acute myeloid leukemia. Abstract:  BACKGROUND: Decitabine is widely used in the treatment of acute myeloid leukemia (AML) in elderly patients. Low-dose Vitamin C has also been indicated to induce DNA demethylation at the cellular level. However, little is known whether low-dose Vitamin C has a synergistic effect with decitabine in clinic.METHODS: The effect of combined low-dose Vitamin C and decitabine on cell proliferation, the cell cycle, apoptosis and the expression level and activity of TET2 was investigated in HL60 and NB4 human leukemic cells. Additionally, we analyzed the clinical outcomes of 73 elderly AML patients who received A-DCAG (intravenous Vitamin C [IVC] plus DCAG [n=39]) or DCAG (n=34) treatment.RESULTS: We found that low-dose Vitamin C and decitabine has a synergistic efficacy on proliferation, apoptosis, TET2 expression and activity, compared to drug-alone treatment in HL60 and NB4 cell lines in vitro. In clinic, feasibility and safety evaluations revealed that patients who received A-DCAG regimen have a higher complete remission (CR) rate than those who received the DCAG regimen (79.92% vs. 44.11%; P=0.004) after one cycle of chemotherapy. The median overall survival (OS) was better in the A-DCAG group compared with the DCAG group (15.3 months vs. 9.3 months, P=0.039). Patients with adverse cytogenetics did benefit from CR. There was no clinically significant additional toxicity observed with the addition of IVC.CONCLUSION: On the basis of these results, the addition of IVC at low doses to DCAG appeared to improve CR and prolong OS, compared with DCAG, in elderly patients with AML.

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17:38

Everything You Need to Know About Gluten "IndyWatch Feed Health"

By Lisa Egan 

For several years now, gluten has been the subject of much debate, discussion, and disagreement.

Grocery stores and restaurants now offer a plethora of gluten-free products and meals.

You might have friends or family members who avoid gluten. Perhaps you follow a gluten-free diet, or have been paying closer attention to food labels and avoid it most of the time.

Maybe you arent even exactly sure what the heck gluten IS and are wondering why so many people avoid it like the plague.

So what is this all about, anyway?

Is gluten-free just another trendy health movement, or is there something to this way of eating?

Lets start with the basics.

What IS gluten?

Gluten is a complex two-part protein found in grains such as wheat, rye, barley, and spelt. The two different proteins that comprise gluten are called glutelin and gliadin. Breads, cereals, and baked goods are obvious sources of gluten (unless they are labeled gluten-free), but they arent the only foods that contain the protein it can be found in many items, even those you wouldnt expect.

There ARE people who absolutely should avoid gluten entirely. Lets discuss the health conditions that make the consumption of gluten dangerous.

...

17:12

Why Is There More Flu This Season: An Uncommon Investigation "IndyWatch Feed Health"

By Catherine J. Frompovich

Even with all the admonitions to receive annual flu vaccines, which really dont protect individuals [1] but actually destabilize human immune systems, along with daily media reports of growing numbers of supposed influenza (flu) outbreaks, I got to wondering why that was happening and what could be involved, since Im a retired healthcare professional and consumer health researcher to this day whose curiosity prompts that something seemingly is not jiving. Was a new pandemic being trial floated? Anyway, whats going on?

From personal experience, the only time I ever contracted the flu was in 1957 when I was young, dumb, and didnt know better when I was taken and given a flu vaccine where I worked. What a disaster! I almost died twice; missed work for close to a month; had a relapse; the family doctor came to the house daily and told me never to get another flu vaccine, as the next one probably would do me in! That was the only time in my lifeand I will be 80 years young my next birthdaythat I ever had the flu! Also, Ive never had another flu shot, either.

As a result of my studies, professional practice and ongoing research, etc., Ive learned some things that most ordinary folks just dont know, e.g., dont believe the propaganda Big Pharma dispenses, as most of it is fudgedperhaps bogus consensus scienceand manufactured to their prescribed liking in order to get their products approved for licensure, especially vaccines for which manufacturers have no legal product liability or responsibilities, thanks to the U.S. Congress in 1986. Youre on your own if damaged by vaccines!

With the above caveats d...

17:00

Journal retracts letter for missing disclosure author says he tried to submit "IndyWatch Feed Health"

An emergency medicine journal has retracted a letter to the editor, saying it didnt include the authors relevant commercial interestwhich the author says he tried to disclose when he submitted the paper. The author, Guy Weinberg, told Retraction Watch he had noted his conflict of interest when he submitted the letter last March, but said []

The post Journal retracts letter for missing disclosure author says he tried to submit appeared first on Retraction Watch.

16:41

BEATING BREAST CANCER "IndyWatch Feed Health"

Women perceive their psycho-emotional relationships with children, mates, parents, siblings, direct relatives, friends in their breasts; therefore, the breast is the most susceptible organ to react to a surprising, shocking psycho-emotional event. As all other diseases, breast cancer is a result of very specific psychological stressors (conflicts) which must be known to help- heal the

16:15

Autism is a Crisis Requiring Urgent Solutions across the Spectrum "IndyWatch Feed Health"

January 17, 2017 The other day, I shared a blog regarding the current autism rates to my personal Facebook page. I shared it because I find it infuriating that we are still in a place where we are downplaying both the Continue reading

The post Autism is a Crisis Requiring Urgent Solutions across the Spectrum appeared first on The Thinking Moms' Revolution.

15:24

Vaccinated Boy Dies From Flu Like Symptoms In Michigan "IndyWatch Feed Health"

12-year old Michael Messenger died Thursday morning due to flu-like symptoms. He left behind a little sister. Michaels mom, Jessica Decent-Doll,  told The Times Herald, Dont wait, its all I can say. This flu or whatever is...

The post Vaccinated Boy Dies From Flu Like Symptoms In Michigan appeared first on Vaxxter.

14:20

Infiltrative Pseudoscience "IndyWatch Feed Health"

If you don't think that CAM is the enemy of science in medicine, then you don't understand CAM and its proponents. Don't be fooled by their marketing. They want a return to the pre-scientific days when health gurus could sell any snake oil they want at exorbitant prices, with any hyped claims that they want, without going through all that tedious science.

14:00

Authors who lost two papers for plagiarism will be fired from university: report "IndyWatch Feed Health"

Researchers from Nepal who had two papers retracted last year for plagiarism will face sanctions, according to a local media report. According to coverage last month from Republica, a news outlet in Nepal, the editor of Bali Medical Journal said he will blacklist the six authors. In a follow-up article, Dipak Shrestha, associate dean of []

The post Authors who lost two papers for plagiarism will be fired from university: report appeared first on Retraction Watch.

13:58

What Should We Really Call Psychiatric Drugs? "IndyWatch Feed Health"

There is a single scientific term that most appropriately describes psychiatric drugs. Not long ago, I used it in court on several occasions during my testimony to explain why psychiatric drugs can have such disastrous effects on the brain, mind, and behavior.

My use of the term angered experts on the other side who declared, in effect, if you search the scientific literature, only Dr. Breggin uses that word to describe psychiatric drugs. In fact, there is a long tradition of using the dread word that has been largely expunged from the official psychiatric literature but remains alive in research and at times pops up in the clinical literature.

The dread word, which I urge everyone to start using on a regular basis, is neurotoxin. The word neurotoxin so unhinges my colleagues because it is a true descriptor for every psychiatric chemical and because it opens the door to an honest analysis of how these poisons impact on the human brain and mental life.

What is a Neurotoxin?

A toxin is any substance poisonous to an organism.  A neurotoxin is a substance that alters the structure or function of the nervous system. A similar alternative definition for neurotoxin is a poisonous substance that acts on the nervous system and disrupts the normal function of nerve cells. Medically, a neurotoxin is any toxin that acts specifically on nervous tissue.1

There is no rational way to argue against putting psychiatric chemicals into the category of neurotoxins. All psychiatric substances alter the structure or functions of the nervous system and disrupt the normal function of nerve cells. All of them act specifically on nervous tissue.

How Drug Companies Seek to Create Psychiatric Neurotoxins

Drug companies tailor their future products to disrupt and alter the brain functions of normal animals before they begin to test them on humans. When a potential psychiatric drug fails to alter, disrupt or impair normal function in the mammalian brain, the drug companies discard it as useless for a psychiatric treatment.

Prozac, for example, resulted from an intense search for a chemical that would disrupt the normal functioning of serotonin neurotransmission in the animal and human brain. Similarly, it is not a coincidence that all antipsychotic drugs...

13:50

The Vaccine Program: Betrayal of Public Trust & Institutional Corruption "IndyWatch Feed Health"

Shades of Dreyfus & BMJs Descent into Tabloid Science

 

By Vera Sharav

 

Note from the WMP Team: In the coming days, WMP will republish Vera Sharavs Betrayal of Public Trust & Institutional Corruption: Vaccine Safety Assessments & Vaccine Science Falsified to Support Vaccination Policy  originally published on the website: Alliance for Human Research Protection. Ms. Sharav is a Holocaust survivor and a fierce critic of the medical establishment. Her research is a must-read by those in our community because it explains the intricate groundwork that has led us to the debacle we are now living with an epidemic of sick children. Through understanding the past, we can change the future.

Following is the first of a seven-part series of Sharavs in-depth expos of the complex and widespread corruption that exists in the vaccination program. Her investigation has uncovered decades-long fraudulent activity that has permeated the vaccine industry. 

Sharavs Introduction: I have undertaken this review of the case against Dr. Andrew Wakefield because the issues involved are far more consequential than the vilification of one doctor. The issues, as I see them, involve (a) collusion of public health officials to deceive the public by concealing scientific evidence that confirms empirical evidence of serious harm linked to vaccines in particular polyvalent vaccines; (b) the willful blindness by the medical community as it uncritically fell in line with a government dictated vaccination policy driven by corporate business interests.

Public health officials and the medical profession have abrogated their professional, public, and human responsibility, by failing to honestly examine the iatrogenic harm caused by expansive, indiscriminate, and increasingly aggressive vaccination policies. On a human level, the documented evidence shows a callous disregard for the plight of thousands of children who suffer irreversible harm, as if they were unavoidable collateral damage.

Indeed, the adjudicated evidence refutes the case against Dr. Wakefield; the documents and testimonies demonstrate that there is no evidence whatsoever, to support the charges of professional misconduct, much less the accusation of fraud.

All of the documented evidence and testimonies submitted to the General Medical Council, upon w...

12:38

Flawed Research Methods Exaggerate The Prevalence of Depression "IndyWatch Feed Health"

The common practice of using patient self-report screening questionnaires rather than diagnostic interviews conducted by researchers has resulted in overestimates of the prevalence of depression, according to an analysis in CMAJ (Canadian Medical Association Journal)

12:03

Anti-Freud: Karl Kraus Criticism of Psychoanalysis and Psychiatry "IndyWatch Feed Health"

In this piece for Psychiatric Survivors, John C. Hancock discusses the work of Karl Kraus, who was praised by Thomas Szasz as one of the greatest early critics of Freudian psychoanalysis and psychiatry.

Szasz appreciates Kraus not only for his bold opposition to psychiatry and psychoanalysis, but also because Kraus was a proponent of individual liberty and responsibility. Unlike Freud, he was, in Szaszs estimation, a man of integrity. He was a noble rhetorician, that is, a master artist and poet who worked in the medium of language to persuade his audience toward that which is good, and away from that which is evil.

12:02

Psychiatry is a Disaster Area in Healthcare That Needs Attention "IndyWatch Feed Health"

In this piece for The BMJ, Dr. Peter Gtzsche points out several of the major problems with the drug-based paradigm of psychiatric care as well as psychiatric drug trials.

12:01

Mental Health Seclusion to be Scrapped After UN Condemnation "IndyWatch Feed Health"

From Stuff: In 2015, the United Nations Committee Against Torture expressed concern at New Zealands use of seclusion against mental health patients. According to a new target set by health authorities, the practice of secluding mental health patients should be abandoned within two years.

Article

12:00

Hep B Vaccination at Birth May Not be Necessary in India, Says Study "IndyWatch Feed Health"

By Jacob Puliyel MD MRCP M Phil A large multi-centre study done in North India shows that many newborns are protected at birth by natural antibodies to Hepatitis-B and so Hep-B vaccination at birth is not necessary. The study funded...

07:00

How Alcohol Damages Your DNA "IndyWatch Feed Health"

By Dr. Mercola

According to the Substance Abuse and Mental Health Services Administration, just over 26 percent of people over 18 reported binge drinking in the previous 30 days of the study when it was performed in 2015.1 Another 7 percent reported heavy alcohol use. This is congruent with the U.S. Surgeon Generals Report showing that substance abuse in the U.S. is skyrocketing, including alcohol abuse.2

According to the Centers for Disease Control and Prevention (CDC), alcohol poisoning kills six people every day.3 These are deaths related to short-term consumption of toxic amounts of alcohol that leads to central nervous system depression and shutdown in critical areas of the brain controlling breathing, heart rate and body temperature, ultimately resulting in death.4 This statistic does not address other negative effects alcohol has on your health.

In addition to being a central nervous system depressant, alcohol is a carbohydrate lacking in real nutritional value. Nearly one-third of Americans are obese and according to the CDC, in 2014 there was no state in the U.S. with a prevalence of obesity less than 20 percent.5

Although scientists have found associations between alcohol consumption and negative health conditions such as pancreatitis and stomach cancer, what has been missing is the precise nature in which alcohol damages your body. New research shows that as your body processes alcohol, a transient toxic compound is produced that attacks DNA.6

Alcohol Damages DNA and Increases Risk for Cancer

The research7 demonstrated the effect alcohol had on blood stem cells in mice. The researchers gave ethanol to mice and then used chromosome analysis and DNA sequencing to study genetic damage on the body by acetaldehyde, produced during the metabolic processing of alcohol.

The researchers from Cambridge Universitys MRS Laboratory of Mo...

Friendly User's Guide for the Timing of Nutritional Supplements "IndyWatch Feed Health"

30 Tips in 30 Days Designed to Help You Take Control of Your Health

This article is part of the 30 Day Resolution Guide series. Each day a new tip will be added designed to help you take control of your health. For a complete list of the tips click HERE

By Dr. Mercola

According to an investigation published in JAMA in 2016, 52 percent of American adults reported using nutritional supplements in 2012, a statistic that has remained stable since 1999.1 While the use of multivitamins has decreased somewhat, from 37 to 31 percent in that timeframe, use of vitamin D and omega-3 supplements have dramatically increased.

Vitamin D use jumped from just over 5 percent to 19 percent, and fish oil supplements increased from just over 1 percent to 12 percent. Among the most popular supplements are probiotics, omega-3, multivitamins, vitamin C, turmeric, calcium and magnesium.2 In all, Americans spent an estimated $21 billion on nutritional supplements in 2015.3

While dietary supplements are generally safe, when and how you take them such as with or without food, or before or after exercise4 can make a difference both in terms of safety and effectiveness. Certain supplements may also be contraindicated for certain health conditions or if youre taking a particular drug. Following, youll find helpful guidance on the use of common supplements, including many sold in my online store.

Quick Guide to the Timing of Supplements

...

02:51

WHO AM I? And Why EVERYTHING Is Riding on It "IndyWatch Feed Health"

Understandably, we mood and anxiety disorder warriors are full of questions. "Why am I depressed?" "Is there a cure for anxiety?" "Am I mentally ill?" I mean, there are jillions of 'em. But one reigns supreme, and I'm not so sure it gets asked enough, if at all. And everything is riding on it. So tap on in and let's get after it...

01:37

Silymarin has positive efficacy to reduce transaminases levels in NAFLD patients. "IndyWatch Feed Health"

PMID:  Medicine (Baltimore). 2017 Dec ;96(49):e9061. PMID: 29245314 Abstract Title:  The therapeutic effect of silymarin in the treatment of nonalcoholic fatty disease: A meta-analysis (PRISMA) of randomized control trials. Abstract:  BACKGROUND: Silymarin (SIL) is an active extraction of the silybum marianum, milk thistle, which is an ancient medicinal plant for treatment of various liver diseases for centuries. This study is to assess the therapeutic effect of SIL in the treatment of nonalcoholic fatty liver disease through meta-analysis.METHODS: Published randomized controlled trials (RCTs) were included from electronic databases (PubMed, Embase, Cochrane library, Web of Science, and so forth). Cochrane handbook was applied to evaluate the methodological quality. All statistical analyses were directed by Revman 5.3 software, and statistical significance was defined as P

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00:55

Protective effects of combined -caryophyllene and silymarin against ketoprofen-induced hepatotoxicity. "IndyWatch Feed Health"

PMID:  Can J Physiol Pharmacol. 2016 Jul ;94(7):739-44. Epub 2016 Mar 9. PMID: 27124106 Abstract Title:  Protective effects of combined-caryophyllene and silymarin against ketoprofen-induced hepatotoxicity in rats. Abstract:  Ketoprofen (Ket), widely utilized in treatment of many inflammatory disorders, is found to induce liver toxicity especially with overdose. This study aimed to evaluate the possible protective effects of concomitant-caryophyllene (Cary) and silymarin (Sily) against Ket-induced hepatotoxicity in rats. Forty adult male albino rats were divided into 5 groups (each n = 8): the control group received distilled water for 6 weeks; the Ket-treated group received distilled water for 5 weeks and Ket in a dose of 8 mgkg(-1)day(-1) p.o. for the 6th week; the Cary + Ket treated group received Cary in a dose of 200 mgkg(-1)day(-1) orally for 6 weeks and Ket for the 6th week; the Sily + Ket treated group received Sily in the dose of 150 mgkg(-1)day(-1) for 6 weeks and Ket for the 6th week; and the Cary + Sily + Ket treated group received Sily and Cary for 6 weeks and Ket for the 6th week. At end of the experiment, serum ALT, AST, and albumin and liver total antioxidant capacity (t.TAC) and malondialdehyde (t.MDA) were measured in all rats. Ket increased serum ALT and AST and t.MDA and decreased t.TAC. Cary and Sily improved these changes. Combined Cary and Sily restored these liver changes to nearly normal. Combined Cary and Sily is hepatoprotective, with the ability to scavenge oxidants against Ket-induced hepatotoxicity in rats.

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00:18

Beta-caryophyllene has the potential efficacy in preventing and ameliorating nonalcoholic fatty liver disease and its associated metabolic disorders. "IndyWatch Feed Health"

PMID:  Mol Nutr Food Res. 2016 Oct ;60(10):2228-2242. Epub 2016 Jun 16. PMID: 27234712 Abstract Title:  -Caryophyllene attenuates palmitate-induced lipid accumulation through AMPK signaling by activating CB2 receptor in human HepG2 hepatocytes. Abstract:  SCOPE: Nonalcoholic fatty liver disease is currently the most common chronic liver disease worldwide, characterized by excessive hepatic lipid accumulation without significant ethanol consumption. We have performed a screening for medicinal foods that inhibit hepatocytic lipid accumulation through activation of AMP-activated protein kinase (AMPK), which is a critical regulator of the hepatic lipid metabolism.METHODS AND RESULTS: We found that clove (Syzygium aromaticum), which is commonly used as a spice, markedly inhibits palmitate-inducible lipid accumulation in human HepG2 hepatocytes. Analyses of the clove extracts found that-caryophyllene, an orally-active cannabinoid, is the principal suppressor of the lipid accumulation, and stimulates the phosphorylation of AMPK and acetyl-CoA carboxylase 1 (ACC1). Our data also showed that -caryophyllene prevents the translocation of sterol regulatory element-binding protein-1c(SREBP-1c) into the nucleus and forkhead box protein O1 (FoxO1) into the cytoplasm through AMPK signaling, and consequently, induces a significant downregulation of fatty acid synthase (FAS) and upregulation of adipose triglyceride lipase, respectively. Moreover, we demonstrated that the -caryophyllene-induced activation of AMPK could be mediated by the cannabinoid type 2 receptor-dependent Ca2+ signaling pathway.CONCLUSION: Our results suggest that-caryophyllene has the potential efficacy in preventing and ameliorating nonalcoholic fatty liver disease and its associated metabolic disorders.

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00:05

Homemade Pregnancy Tests: How Accurate Are They? "IndyWatch Feed Health"

Homemade pregnancy tests can be useful to discretely check to see if you are pregnant or not. Making your own pregnancy test is very simple and it works on the same principle as regular pregnancy testing kits. A hormone in your urine creates a chemical reaction with a natural substance which can help you to know if you are pregnant or not.

Some natural ingredients in DIY pregnancy tests include vinegar, baking soda, soap, dandelion leaves, or sugar. So, you probably already have most of these things in your home to make your own low-cost pregnancy test kit. If you think you are pregnant and want to quickly check if you are pregnant or not, one of these DIY home pregnancy tests might work for you.

In this article, Im going to look at some of the most popular traditional homemade pregnancy tests that have been used for centuries. I will also discuss some of the advantages and disadvantages of making your own testing kits to check for pregnancy at home.

What Are Homemade Pregnancy Tests?

Pregnancy testing kits that you can buy in the pharmacy and check for pregnancy at home are a relatively new invention. According to the National Institutes of Health, it wasnt until the 1970s when pregnancy kits were made widely available.1

Homemade methods of testing for pregnancy have been around for thousands of years. For example, the ancient Egyptians poured urine from women who may be pregnant over barley seeds. If a woman was pregnant, then the seeds sprouted and grew quickly. Scientists have actually found that in 70% of the time, this homemade pregnancy test was accurate.

During the middle ages, people would mix urine with wine and observe the results. Scientists say that this type of DIY pregnancy testing would work because proteins in urine react with alcohol.

However, in the late 19th Century and early 20th Century, scientists discovered that certain hormones can be detected in the urine of pregnant women. These discoveries helped to explain why many home pregnancy tests would have worked with varying degrees of accuracy.

How Do Homemade Pregnancy Tests Work?

Homemade pregnancy tests work on the same principle as modern pregnancy tests.

The journal Human Reproduction says that all pregnancy tests measure the amount of the hormone human chorionic gonadotrophin (hCG). Traces of hCG can be detected in the blood and urine of pregnant women as early as 3-4 days after implantation. According to researchers, measuring for hCG is one of the most accurate ways to test for pregnancy....

Tuesday, 16 January

23:42

These findings demonstrate that beta-caryophylleneprovides neuroprotection against rotenone-induced Parkinson disease. "IndyWatch Feed Health"

PMID:  Mol Cell Biochem. 2016 Jul ;418(1-2):59-70. Epub 2016 Jun 17. PMID: 27316720 Abstract Title:  -Caryophyllene, a phytocannabinoid attenuates oxidative stress, neuroinflammation, glial activation, and salvages dopaminergic neurons in a rat model of Parkinson disease. Abstract:  Parkinson disease (PD) is a neurodegenerative disease characterized by progressive dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) area. The present study was undertaken to evaluate the neuroprotective effect of-caryophyllene (BCP) against rotenone-induced oxidative stress and neuroinflammation in a rat model of PD. In the present study, BCP was administered once daily for 4 weeks at a dose of 50 mg/kg body weight prior to a rotenone (2.5 mg/kg body weight) challenge to mimic the progressive neurodegenerative nature of PD. Rotenone administration results in oxidative stress as evidenced by decreased activities of superoxide dismutase, catalase, and depletion of glutathione with a concomitant rise in lipid peroxidation product, malondialdehyde. Rotenone also significantly increased pro-inflammatory cytokines in the midbrain region and elevated the inflammatory mediators such as cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) in the striatum. Further, immunohistochemical analysis revealed loss of dopaminergic neurons in the SNc area and enhanced expression of ionized calcium-binding adaptor molecule-1 (Iba-1) and glial fibrillary acidic protein (GFAP), indicators of microglia activation, and astrocyte hypertrophy, respectively, as an index of inflammation. However, treatment with BCP rescued dopaminergic neurons and decreased microglia and astrocyte activation evidenced by reduced Iba-1 and GFAP expression. BCP in addition to attenuation of pro-inflammatory cytokines and inflammatory mediators such as COX-2 and iNOS, also restored antioxidant enzymes and inhibited lipid peroxidation as well as glutathione depletion. The findings demonstrate that BCP provides neuroprotection against rotenone-induced PD and the neuroprotective effects can be ascribed to its potent antioxidant and anti-inflammatory activities.

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23:25

The cannabinoid 2 receptor agonist -caryophyllene modulates the inflammatory reaction induced by Mycobacterium bovis. "IndyWatch Feed Health"

PMID:  Inflamm Res. 2016 Nov ;65(11):869-879. Epub 2016 Jul 5. PMID: 27379721 Abstract Title:  The cannabinoid 2 receptor agonist-caryophyllene modulates the inflammatory reaction induced by Mycobacterium bovis BCG by inhibiting neutrophil migration. Abstract:  OBJECTIVE AND DESIGN: -Caryophyllene (BCP) is a sesquiterpene that binds to the cannabinoid 2 (CB2) receptor and exerts anti-inflammatory effects. In this study, we investigated the anti-inflammatory effect of BCP and another CB2 agonist, GP1a in inflammatory experimental model induced by Mycobacterium bovis (BCG).METHODS: C57Bl/6 mice were pretreated orally with BCP (0.5-50 mg/kg) or intraperitonealy with GP1a (10 mg/kg) 1 h before the induction of pleurisy or pulmonary inflammation by BCG. The direct action of CB2 agonists on neutrophils function was evaluated in vitro.RESULTS: -Caryophyllene (50 mg/kg) impaired BCG-induced neutrophil accumulation in pleurisy without affecting mononuclear cells or the production of TNF- and CCL2/MCP-1. However, BCP inhibited CXCL1/KC, leukotriene B4 (LTB4), IL-12, and nitric oxide production. GP1a had a similar effect to BCP. Preincubation of neutrophils with BCP (10 M) impaired chemotaxis toward LTB4 and adhesion to endothelial cells stimulated with TNF-, and both, BCP and GP1a, impaired LTB4-induced actin polymerization.CONCLUSION: These results suggest that the CB2 receptor may represent a new target for modulating the inflammatory reaction induced by mycobacteria.

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23:00

These results suggest the potential of Cinnamomum zeylanicum bark essential oil as a natural antimicrobial agent against periodontal disease. "IndyWatch Feed Health"

PMID:  Microb Pathog. 2018 Jan 9 ;116:26-32. Epub 2018 Jan 9. PMID: 29325862 Abstract Title:  Antibacterial effects of cinnamon (Cinnamomum zeylanicum) bark essential oil on Porphyromonas gingivalis. Abstract:  The objective of this study was to investigate the antibacterial effects of cinnamon (Cinnamomum zeylanicum) bark essential oil (CBEO) and its principal constituent cinnamaldehyde against Porphyromonas gingivalis and to elucidate the antibacterial mechanism. GC-MS analysis showed that cinnamaldehyde was the major constituent in CBEO (57.97%). The minimum inhibition concentrations (MICs) of CBEO and cinnamaldehyde were 6.25g/mL and 2.5M for P. gingivalis, respectively. Nucleic acid and protein leakage was observed with increasing concentrations of CBEO and cinnamaldehyde. Additionally, propidium iodide uptake assays revealed CBEO and cinnamaldehyde at 1MIC impaired P. gingivalis membrane integrity byenhancing cell permeability. Morphological changes in P. gingivalis cells were observed by scanning electron microscopy, which indicated cell membrane destruction. To further determine the anti-biofilm effect, relative biofilm formation and established biofilms were examined, which demonstrated that both CBEO and cinnamaldehyde at sub-MIC levels inhibited P. gingivalis biofilm formation by 74.5% and 67.3% separately, but only CBEO slightly decreased established biofilms by 33.5% at 4MIC. These results suggest the potential of CBEO as a natural antimicrobial agent against periodontal disease. Furthermore, cinnamaldehyde was confirmed to be the antibacterial substance of CBEO with inhibitory action against P. gingivalis.

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22:26

These findings revealed that rosemary ethanolic extracts protects from toxic effects of lead. "IndyWatch Feed Health"

PMID:  Exp Toxicol Pathol. 2016 Sep ;68(8):451-61. Epub 2016 Jul 21. PMID: 27449700 Abstract Title:  Protective effects of ethanolic extract of rosemary against lead-induced hepato-renal damage in rabbits. Abstract:  In traditional medicine, Rosmarinus officinalis L. leaf is used as a curative herbal therapy for the treatment of several diseases. The protective effects of rosemary in toxic effects of some environmental pollutants are known. However, there is paucity of information about its protective effects on lead acetate (LD) toxicity. To assess the protection of rosemary ethanolic extracts (REE) on LD-induced hepato- and nephro-toxicity, male albino rabbits were treated with REE (30mg/kg) and/or LD (30mg LD/kg) by gavage administration for 30 days. The total phenolic compound content in REE was estimated using Folin-Ciocalteu's assay and phyto-constituents were isolated and identified using gas chromatographic and mass spectrometry (GC-MS) analysis. The protective effect of REE in LD-induced liver and renal dysfunction and blood cells was evaluated by estimating blood biomarkers of liver and renal damage, histological, and biochemical examinations. Antioxidant enzyme activities, lipid peroxidation biomarker, protein and glycogen contents were estimated in both liver and kidney homogenates. The GC-MS analysis revealed that REE is rich in phenolic compounds including camphor, phytol, borneol, caryophyllene oxide, isopulegol, thymol, and verbenone. REE pre-treatment significantly (P

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22:13

The Ocean City Lawsuit Explained, a Bit. "IndyWatch Feed Health"

OC Blog photo 2018Ocean City, Maryland, Spring 2017. This photo was taken just before the Town of Ocean City passed the emergency ordinance addressing the panic officials claim bare-chested women would create on the beach.

 

So after a summer of patient deliberation turned into an autumn of patient deliberation, we have finally filed our civil rights complaint against the Town of Ocean Citys unconstitutional ordinance banning female, but not male, bare-chestedness.

Rather than rehash the story, which is easy enough to find on this blog and through a simple Google search, I thought I would instead do an FAQ about topfreedom and what parts of this lawsuit I can speak to for the benefit of supporters and detractors checking in here as a result of the recent news coverage regarding our lawsuit.

Please understand that I cannot answer certain questions, mostly the ones that require me to make legal arguments.  Lawyers are involved now finally.  Thank goodness.  So with that said, welcome, or welcome back.  Im excited to have this underway.

Q:  There are so many bigger concerns in the...

22:12

Sage extract at low dose exhibits similar effects to rosiglitazone. "IndyWatch Feed Health"

PMID:  PeerJ. 2018 ;6:e4166. Epub 2018 Jan 9. PMID: 29333341 Abstract Title:  Preventive effects of Salvia officinalis leaf extract on insulin resistance and inflammation in a model of high fat diet-induced obesity in mice that responds to rosiglitazone. Abstract:  Background: Salvia officinalis (sage) is a native plant to the Mediterranean region and has been used for a long time in traditional medicine for various diseases. We investigated possible anti-diabetic, anti-inflammatory and anti-obesity effects of sage methanol (MetOH) extract in a nutritional mouse model of obesity, inflammation and insulin resistance, as well as its effects on lipolysis and lipogenesis in 3T3-L1 cells.Methods: Diet-induced obese (DIO) mice were treated for five weeks with sage methanol extract (100 and 400 mg kg-1/day bid), or rosiglitazone (3 mg kg-1/day bid), as a positive control. Energy expenditure, food intake, body weight, fat mass, liver glycogen and lipid content were evaluated. Blood glucose, and plasma levels of insulin, lipids leptin and pro- and anti-inflammatory cytokines were measuredthroughout the experiment. The effects of sage MetOH extract on lipolysis and lipogenesis were tested in vitro in 3T3-L1 cells.Results: After two weeks of treatment, the lower dose of sage MetOH extract decreased blood glucose and plasma insulin levels during an oral glucose tolerance test (OGTT). An insulin tolerance test (ITT), performed at day 29 confirmed that sage improved insulin sensitivity. Groups treated with low dose sage and rosiglitazone showed very similar effects on OGTT and ITT. Sage also improved HOMA-IR, triglycerides and NEFA. Treatment with the low dose increased the plasma levels of the anti-inflammatory cytokines IL-2, IL-4 and IL-10 and reduced the plasma level of the pro-inflammatory cytokines IL-12, TNF-, and KC/GRO. The GC analysis revealed the presence of two PPARs agonist in sage MetOH extract. In vitro, the extract reduced in a dose-related manner the accumulation of lipid droplets; however no effect on lipolysis was observed.Conclusions: Sage MetOH extract at low dose exhibits similar effects to rosiglitazone. It improves insulin sensitivity, inhibits lipogenesis in adipocytes and reduces inflammation as judged by plasma cytokines. Sage presents an alternative to pharmaceuticals for the treatment of diabetes and associated inflammation.

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22:00

Dr Ron Unfiltered Uncensored with Guest Dr Bennet Omalu Episode 241 "IndyWatch Feed Health"

Drs Ron and Dan are honored to have the world famous Dr Omalu (the concussion doctor) as a guest. He was portrayed by Will Smith in the movie "Concussion" He is joing us from California to give us the latest advances in CTE and concussions. His recent book "Truth Doesn't Have a Side" is a must read for all parents, grandparents and care givers.  Dr Dan and I interviewed Dr Bennet and are honored to present him today in his first appearance on our podcast.   You can call in to listen at 347-989-8899 Thank you

21:48

By ICIM member Jerry Tennant, MD: Why is voltage so important for us to live a healthy pain free lifestyle? "IndyWatch Feed Health"

 

When talking about pain management, I often refer to energy medicine as a modality to aid in the healing process. We require stored energy in the body for daily living. This energy comes through our water, food, nutrition and exercise. If we become ill or are in chronic pain, a lot of our bodys energy is directed toward our natural healing systems. Sometimes our bodies run out of this energy and that can lead to chronic pain or disease.

Dr. Jerry Tennant MD, made a statement in a presentation that resonated with me the first time I heard it. Chronic disease and pain only occurs when the body loses the voltage it needs to make new cells that work.

The traditional means of treatment (drugs, medications etc.) plus many of the things that we eat and drink can rob us of voltage. However with the proper intake of alkaline water, good nutrition and energy medicine we can bring our bodies back into balance energetically, helping us achieve the pain free healthy lifestyle weve always wanted.

After working with microcurrent modalities for many years, I have experienced firsthand how remarkable this subtle energy helps to accelerate the healing process. I believe it is important for everyone to understand that our body is portable electronic device and uses electrons or voltage in order to function. These Blogs are intended to help us understand why voltage and electrons are so important for us to be well.

A good starting point for anyone who wants to learn how the body works is to read a book entitled Healing is Voltage the Handbook by Dr. Jerry Tennant. In his book Dr. Tennant discusses energy medicine, the importance of alkaline water, pH of the body, nutrition, dental etc. He explains, in a very easy to understand way, why all of these are necessary for us to be healthy and well.

Dr Tennant also teaches us how to be good electricians of the body and how to make it work better. Understanding his refreshingly honest medical paradigm and passing it forward to as many people as possible, has been his mission for the past 15 years.

To learn more, visit the article page of this site.

Yours in good health.

21:18

Top 5 Reasons NEVER to Take a Proton Pump Inhibitor "IndyWatch Feed Health"

Millions of doses of "acid blocking" proton pump inhibitor drugs are doled out every year, yet most doctors and their patients are completely oblivious to their unintended, adverse effects, which include increased risk for premature death. 

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21:16

This review discusses the role of eugenol on redox status and its potential use in the treatment and prevention of cancer. "IndyWatch Feed Health"

PMID:  Nutrients. 2017 Dec 17 ;9(12). Epub 2017 Dec 17. PMID: 29258206 Abstract Title:  The Dual Antioxidant/Prooxidant Effect of Eugenol and Its Action in Cancer Development and Treatment. Abstract:  The formation of reactive oxygen species (ROS) during metabolism is a normal process usually compensated for by the antioxidant defense system of an organism. However, ROS can cause oxidative damage and have been proposed to be the main cause of age-related clinical complications and diseases such as cancer. In recent decades, the relationship between diet and cancer has been more studied, especially with foods containing antioxidant compounds. Eugenol is a natural compound widely found in many aromatic plant species, spices and foods and is used in cosmetics and pharmaceutical products. Eugenol has a dual effect on oxidative stress, which can action as an antioxidant or prooxidant agent. In addition, it has anti-carcinogenic, cytotoxic and antitumor properties. Considering the importance of eugenol in the area of food and human health, in this review, we discuss the role of eugenol on redox status and its potential use in the treatment and prevention of cancer.

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21:00

Is Your Child Smarter Or Dumber Because Of Microwave Technologies? "IndyWatch Feed Health"

By Catherine J. Frompovich

Parents are overjoyed when their two-year-olds master computer games and cell phones. They interpret that as look how smart my kid is! Well, thats really not the take-away message parents should be coming up with. Maybe their youngsters inadvertently are becoming addicted to a tech-meme and device, which will damage them down the road, and very dramatically: dumb and cancer?

Source

I refer readers to the United Nations IARC Press Release of May 31, 2011 wherein

The WHO/International Agency for Research on Cancer (IARC) has classified radiofrequency electromagnetic fields as possibly carcinogenic to humans (Group 2B), based on an increased risk for glioma, a malignant type of brain cancer1, associated with wireless phone use.

...

19:14

Women's Sexual Freedom and Enjoyment is Being Hijacked: 30 Million Women Want To Know Why "IndyWatch Feed Health"

30 million women in the United States are suffering from chronic pelvic pain.  Which means that 30 million women are suffering from debilitating and embarrassing symptoms such as urine leaking, painful sex, weak or non-existent orgasms and pelvic organ prolapse. (1-3) This is the silent female health epidemic that no one is talking about  

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15:34

7 Vaccinated Die From Flu In Santa Barbara "IndyWatch Feed Health"

This years flu spectacle is showing no indications of letting up, at least not from the medias perspective. Daily reports on death tolls which are being blamed on the flu continue to make headlines. It...

The post 7 Vaccinated Die From Flu In Santa Barbara appeared first on Vaxxter.

15:11

Illinois Health Officials Issue Measles Alert "IndyWatch Feed Health"

According to NBC News, a passenger traveling through Chicagos OHare airport did so while having measles. They claim the passenger, who remained unnamed, passed through Terminal 1 on the morning of last Wednesday. There are...

The post Illinois Health Officials Issue Measles Alert appeared first on Vaxxter.

13:06

Being Bilingual Helps Autistic Children "IndyWatch Feed Health"

Children with Autism Spectrum Disorders (ASD) often have a hard time switching gears from one task to another. But being bilingual may actually make it a bit easier for them to do so, according to a new study which was recently published in Child Development.

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