IndyWatch Health Watch Feed Archiver

Go Back:30 Days | 7 Days | 2 Days | 1 Day

IndyWatch Health Watch Feed Today.

Go Forward:1 Day | 2 Days | 7 Days | 30 Days

IndyWatch Health Watch Feed was generated at Community Resources IndyWatch.

Tuesday, 14 August

00:39

Are Front-line Emergency Room Doctors the Key to Identifying Vaccine Injuries and Reporting Them? "IndyWatch Feed Health"

Who Can Parents Trust Book

Health Impact News

Are front-line emergency room doctors the key to identifying vaccine injuries and reporting them?

At least one ER doctor thinks so.

David Denton Davis MD, a former Emergency Physician, claims neither our Centers for Disease Control (CDC) nor our Department of Health and Human Services (HHS) has requested help from the American College of Emergency Physicians (ACEP) in identifying illnesses and deaths occurring hours, days and weeks following childhood vaccinations.

In his soon to be published book Who Can Parents Trust? Vaccines: Avoidable and Unsafe, he claims the vast majority of serious vaccine related illnesses coming into Emergency rooms will continue to go unrecognized, unless nurses and physicians ask the last vaccination date (LVD).

He believes during the past thirty years several million serious Adverse Events (AEs), including deaths presenting nationwide to more than 5,000 Emergency rooms have never been recognized, documented or submitted for investigation, in accordance with our National Childhood Vaccine Injury Act (NCVIA). All suspicions of a vaccine related adverse event are required by law, to be submitted using our Vaccine Adverse Event Reporting System (VAERS).

Sadly, he goes on, very few Emergency Physicians or Nurses have received any NCVIA or VAERS education.

As a charter member of ACEP, Dr. Davis served on the Board of Directors during the creation of Emergency Medicine (EM) as a specialty. He admits his own reporting failures were due to a lack of vaccine education.

Dr. Davis states he is concerned many pediatricians know, but are not reporting illnesses following vaccinations, for financial reasons. Although neither makers nor physicians are liable for vaccine damage, the ultimate truth for safety was made contingent on investigating physician, parent or third party VAERS submissions.

With only a very small percentage being reported no one can honestly say vaccines are safe.

At a time when our vaccine industry is rolling out newer and, perhaps, more dangerous products, he believes it is time to call a temporary h...

Go Back:30 Days | 7 Days | 2 Days | 1 Day

IndyWatch Health Watch Feed Today.

Go Forward:1 Day | 2 Days | 7 Days | 30 Days

Monday, 13 August

23:59

Exposing How Child Abuse Pediatricians Medically Kidnap Children: A Guide for Parents "IndyWatch Feed Health"

Mothers in Prison. Imprisonment of one parent entails the forcible separation of a child, who is suffering badly illustration

by Terri LaPoint
Health Impact News

It happens every day in America. Loving parents take their children to the emergency room for accidents, injuries, and illness.

Sometimes the child appears to be fine, but to be on the safe side, parents just want to get their child checked out.

Other times, the parents dont know whats wrong, but they look to the experts to figure out what is going on. They are worried about their child.

The last thing on their mind is that someone could come in and take their child away from them, accusing them of child abuse.

Yet it is becoming increasingly common for a trip to the doctor or hospital to escalate quickly into this kind of nightmare scenario. A concern for the health of their child becomes a fight for the very survival of the family unit as parents are blindsided by Child Abuse Pediatricians and social workers.

Policies designed to help medical staff spot real child abuse can actually set up innocent parents for false allegations of abuse. Parents walking into a medical setting seeking help for their child often have no idea that they may be walking into a trap.

The American Academy of Pediatrics (AAP) is a professional organization of pediatricians. Their policies impact the practices of local pediatricians and doctors in Childrens Hospitals.

The public usually pays little attention to specific AAP policies. Policies are generally assumed to be based on scientific evidence, but there are times that politics, agendas, or financial incentives play a role in establishment of policies.

Parents (consumers) have a right to know about the policies of a business or establishment they choose to interact with, especially when those policies can have a significant impact on the well-being of their family.

Trapped, Like a Dolphin in a Net

After a report from a Child Abuse Pediatrician at Helen DeVos Childrens Hospital (HDVCH) in Grand Rapids, Michigan, resulted in children being temporarily being taken from innocent parents, the doctor thanked them for taking a hard hit for the greate...

23:41

Anti-inflammatory secondary metabolites from the leaves of Rosa laevigata. "IndyWatch Feed Health"

PMID:  Bioorg Med Chem. 2013 Jun 1 ;21(11):3290-7. Epub 2013 Mar 24. PMID: 23632365 Abstract Title:  Anti-inflammatory secondary metabolites from the leaves of Rosa laevigata. Abstract:  Bioassay-guided fractionation of a n-BuOH-soluble extract of the leaves of Rosa laevigata led to the isolation of three new 19-oxo-18,19-seco-ur-sane-type triterpenoids, laevigins A-C (1-3), a new oleanane-type triterpenoid saponin, laevigin D (4), a new geranylmethylbenzoate, 5-[(2E,6S)-6,7-dihydroxy-3,7-dimethyl-2-octen-1-yl]-2-(-D-glucopyranosyloxy)-methyl benzoate (5), together with 9 known compounds (6-14). Their structures were elucidated by spectroscopic and chemical methods. Compounds 4, 9, 11, and 12 significantly suppressed the LPS-stimulated NF-B transcriptional activity and the release of TNF, IL-1, IL-6, and IL-10 in mouse RAW 264.7 macrophages. The compound 12 exhibited moderate inhibition on NF-B transcriptional activity with an IC50 value of 23.21 M. The IC50 values of compound 12 were measured as 14.32, 8.53, 8.04, and10.38 M for the inhibitory activity on TNF-release, IL-1-release, IL-6-release, and IL-10-release, respectively.

read more

23:21

Rosa laevigata fruit could be used in the treatment of NAFLD. "IndyWatch Feed Health"

PMID:  Food Chem. 2013 Dec 1 ;141(3):2108-16. Epub 2013 May 16. PMID: 23870935 Abstract Title:  Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats. Abstract:  The effects and mechanisms of the total flavonoids (TFs) from Rosa laevigata Michx fruit on high-fat diet-induced non-alcoholic fatty liver disease (NAFLD) were investigated in this study. Gavage administration of the TFs significantly decreased the relative liver weight, serum AST and ALT activities, the levels of serum lipid, LDL, blood glucose and insulin, suppressed lipid accumulation in liver, and increased serum HDL level. Moreover, the natural product significantly enhanced SOD activity, increased GSH-Px and GSH contents and decreased the concentration of MDA and CYP2E1 expression as well as prevented mitochondrial membrane potential dysfunctions and ultrastructural alterations. Further mechanism investigation indicated that the TFs inhibited hepatic lipid accumulation by suppressing the expressions of some key molecules in fatty acid synthesis pathway and promoting fatty acid-oxidation, while not by inhibiting cholesterol synthesis. On the base of these, the TFs should be developed as a new drug for treatment of NAFLD.

read more

23:15

Flavonoid-rich extract from R. laevigata Michx fruit has the potential actions for treatment of ischemic stroke. "IndyWatch Feed Health"

PMID:  Neurochem Int. 2013 Nov ;63(5):522-32. Epub 2013 Sep 4. PMID: 24012531 Abstract Title:  Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia-reperfusion injury through suppression of apoptosis and inflammation. Abstract:  The neuroprotective effect and mechanism of the flavonoid-rich extract (FRE) from Rosa laevigata Michx fruit on cerebral ischemia-reperfusion (I/R) injury were investigated. The contents of flavonoids, saponins and tannin were determined, and ten chemicals including chlorogenic acid, 4-hydroxy-3-methoxybenzoic acid, apigenin, luteolin, kaempferol, querce-tin, kaempferide-3-O-glucoside, quercetin-3-rhamnoside, rutin and isorhamnetin-3-O--rutinoside from the crude extract were separated. Oral administration of FRE obviously improved the survival rate and prevented I/R-induced disability and histological damage. Further works showed that the natural product had excellent antioxidant activity, significantly decreased DNA fragmentation, up-regulated the expression of Bcl-2, and down-regulated the expressions of p53, Apaf1, Fas, FasL, Bax, Bid, cytochrome C and active Caspase-3, -9 and -8. Moreover, the FRE decreased the expressions of NF-B, iNOS, MMP-9, COX-2, TNF-, IL-1, IL-4, IL-6, and down-regulated the levels of p-JNK, p-ERK and p-p38 in MAPK pathways. Therefore, the flavonoid-rich extract from R. laevigata Michx fruit has the potential actions for treatment of ischemic stroke due to its anti-oxidant, anti-apoptosis and anti-inflammatory properties.

read more

23:02

Total saponins from Rosa laevigata Michx fruit shows a significant protective effect against acetaminophen-induced liver damage. "IndyWatch Feed Health"

PMID:  Molecules. 2014 May 30 ;19(6):7189-206. Epub 2014 May 30. PMID: 24886943 Abstract Title:  Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis. Abstract:  The effect of the total saponins from Rosa laevigata Michx fruit (RLTS) against acetaminophen (APAP)-induced liver damage in mice was evaluated in the present paper. The results showed that RLTS markedly improved the levels of liver SOD, CAT, GSH, GSH-Px, MDA, NO and iNOS, and the activities of serum ALT and AST caused by APAP. Further research confirmed that RLTS prevented fragmentation of DNA and mitochondrial ultrastructural alterations based on TdT-mediated dUTP nick end labeling (TUNEL) and transmission electron microscopy (TEM) assays. In addition, RLTS decreased the gene or protein expressions of cytochrome P450 (CYP2E1), pro-inflammatory mediators (IL-1, IL-4, IL-6, TNF-, iNOS, Bax, HMGB-1 and COX-2), pro-inflammatory transcription factors (NF-B and AP-1), pro-apoptotic proteins (cytochrome C, p53, caspase-3, caspase-9, p-JNK, p-p38 and p-ERK), and increased the protein expressions of Bcl-2 and Bcl-xL. Moreover, the gene expression of IL-10,and the proteins including LC3, Beclin-1 and Atg5 induced by APAP were even more augmented by the extract. These results demonstrate that RLTS has hepatoprotective effects through antioxidative action, induction of autophagy, and suppression of inflammation and apoptosis, and could be developed asa potential candidate to treat APAP-induced liver damage in the future.

read more

22:58

Tsundoku: The Practice Of Buying More Books Than You Can Read "IndyWatch Feed Health"

If you are one who finds yourself drawn to the printed page, then you are likely familiar with a certain kind of experience. You know what it is to be walking through the isles of your local bookstore, or being inexplicable pulled through the doors of a secondhand shop you discovered in your vacation locale,... View Article

The post Tsundoku: The Practice Of Buying More Books Than You Can Read appeared first on Healthy Holistic Living.

22:54

If You Have An M On Your Palm There Is Something Truly Special About You "IndyWatch Feed Health"

For most people it seems, palm reading is placed in the same category as the fountain of youth and unicorns. It makes for a good time at a carnival, and its fun to hope for the promises of a long life and a rich future, but most wouldnt rely on it as scientific fact. Although... View Article

The post If You Have An M On Your Palm There Is Something Truly Special About You appeared first on Healthy Holistic Living.

22:49

Exposing How Child Abuse Pediatricians Medically Kidnap Children: A Guide for Parents "IndyWatch Feed Health"

Mothers in Prison. Imprisonment of one parent entails the forcible separation of a child, who is suffering badly illustration

by Terri LaPoint
Health Impact News

It happens every day in America. Loving parents take their children to the emergency room for accidents, injuries, and illness.

Sometimes the child appears to be fine, but to be on the safe side, parents just want to get their child checked out.

Other times, the parents dont know whats wrong, but they look to the experts to figure out what is going on. They are worried about their child.

The last thing on their mind is that someone could come in and take their child away from them, accusing them of child abuse.

Yet it is becoming increasingly common for a trip to the doctor or hospital to escalate quickly into this kind of nightmare scenario. A concern for the health of their child becomes a fight for the very survival of the family unit as parents are blindsided by Child Abuse Pediatricians and social workers.

Policies designed to help medical staff spot real child abuse can actually set up innocent parents for false allegations of abuse. Parents walking into a medical setting seeking help for their child often have no idea that they may be walking into a trap.

The American Academy of Pediatrics (AAP) is a professional organization of pediatricians. Their policies impact the practices of local pediatricians and doctors in Childrens Hospitals.

The public usually pays little attention to specific AAP policies. Policies are generally assumed to be based on scientific evidence, but there are times that politics, agendas, or financial incentives play a role in establishment of policies.

Parents (consumers) have a right to know about the policies of a business or establishment they choose to interact with, especially when those policies can have a significant impact on the well-being of their family.

Trapped, Like a Dolphin in a Net

After a report from a Child Abuse Pediatrician at Helen DeVos Childrens Hospital (HDVCH) in Grand Rapids, Michigan, resulted in children being...

22:35

Total flavonoids from Rosa laevigata fruit show good effects against H2O2-induced oxidative injury in PC12 cells. "IndyWatch Feed Health"

PMID:  Molecules. 2014 Aug 7 ;19(8):11816-32. Epub 2014 Aug 7. PMID: 25105919 Abstract Title:  Potent effects of flavonoid-rich extract from Rosa laevigata Michx fruit against hydrogen peroxide-induced damage in PC12 cells via attenuation of oxidative stress, inflammation and apoptosis. Abstract:  Oxidative stress-induced neuronal death has an important role in the pathogenesis of neurodegenerative disorders. The effects and mechanisms of action of the total flavonoids (TFs) from Rosa laevigata Michx fruit against hydrogen peroxide (H2O2)-induced oxidative injury in PC12 cells were investigated in this study. The results demonstrated that the TFs protected against cell apoptosis, DNA and mitochondrial damage caused by H2O2 based on single cell gel electrophoresis, in situ terminal deoxynucleotidyltransferase dUTP nick end labeling (TUNEL), flow cytometry and transmission electron microscope (TEM) assays. In addition, the TFs notably decreased cytochrome C release from mitochondria into the cytosol and intracellular Ca2+ levels, and diminished intracellular generation of reactive oxygen species (ROS). Furthermore, the TFs inhibited the phosphorylation levels of JNK, ERK and p38 MAPK as well as down-regulated the expressions of IL-1, IL-6, TNF-, Fas, FasL, CYP2E1, Bak, caspase-3, caspase-9, p53, COX-2, NF-B, AP-1, and up-regulated the expressions of Bcl-2 and Bcl-xl. In conclusion, these results suggest that the TFs from R. laevigata Michx fruit show good effects against H2O2-induced oxidative injury in PC12 cells by adjusting oxidative stress, and suppression of apoptosis and inflammation, and could be developed as a potential candidate to prevent oxidative stress in the future.

read more

22:13

The Best Iron Supplement: The Complete Guide (Research Based) "IndyWatch Feed Health"

The best types of iron supplements help to address symptoms of iron deficiency or iron deficiency anemia. Iron is an essential nutrient that helps the body to function properly and keeps red blood cells healthy. Proper levels of iron in the body also help to maintain healthy skin, hair, nails, and cells.

Iron is contained in foods that we eat. Meat, poultry, and seafood are the richest sources of available iron. Although there are plant-based sources of iron, these are poorly absorbed by the body.

You may need to take iron supplements if your diet lacks nutrients or you have digestive problems that restrict the absorption of nutrients. Very often, women are at more risk than men from iron deficiency anemia because or pregnancy or heavy menstrual bleeding.

The best iron supplement has high dose of elemental iron per tablet, is relatively inexpensive and is easily absorbed by your body. The best iron pill for anemia or iron deficiency also has minimal side effects such as constipation.

In this guide I will look at what medical research reveals as to the best types of iron supplements on the market. You will also find out if you really need an iron supplement to increase your iron levels.

What is Iron?

Iron is a mineral and its one of the essential nutrients in the body. Researchers from the National Institutes of Health report that iron is stored liver, bone marrow, and spleen as a compound called ferritin. Some traces or iron are also stored in muscle tissue.1

Why Do We Need Iron?

One of the main reasons that we need iron is that it is an essential component of hemoglobin and its required to prevent iron deficiency anemia.

According to Dr. Brunilda Nazario on WebMD, hemoglobin carries oxygen throughout our bodies to every cell and tissue. Because a lack of iron affects levels of oxygen in the blood, iron deficiency anemia can impact on organ function and brain function. Iron is also essential to keep your immune system healthy.2

Dr. Nazario says that women, pregnant women, and infants especially need iron. For example, adequate levels of iron help maintain healthy pregnancies and ensure babies grow properly.

Foods That Contain Iron

It should be possible to obtain enough iron from your diet without having to resort to iron supplementati...

22:10

Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats. "IndyWatch Feed Health"

PMID:  Food Funct. 2014 Dec ;5(12):3065-75. PMID: 25310017 Abstract Title:  Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats. Abstract:  The protective effects of total saponins from Rosa laevigata Michx fruit (RLTS) in high-fat diet (HFD)-induced rats were investigated. The results showed that oral administration of RLTS attenuated hepatic steatosis, significantly reduced the levels of body weight, alanine transaminase, aspartate transaminase, total cholesterol, total triglyceride, free fatty acids, low density lipoprotein, blood glucose, insulin and malondialdehyde, and increased high density lipoprotein and glutathione levels compared with the model group. Further investigations showed that RLTS affected fatty acid synthesis, fatty acid-oxidation, fatty acid -oxidation, total cholesterol and triglyceride metabolism and synthesis. Moreover, the extract obviously suppressed HFD-induced oxidative stress and inflammation. These results suggest that RLTS should be developed to be one functional food or health product against non-alcoholic fatty liver disease (NAFLD) in the future.

read more

22:02

The honey processed root of Rosa laevigata have significant antibacteral effect and anti-inflammatory effect on chronic infammation. "IndyWatch Feed Health"

PMID:  Zhong Yao Cai. 2014 Aug ;37(8):1356-9. PMID: 25726641 Abstract Title:  [Study on antibacterial and anti-inflammatory effects of different processed products of Rosa laevigata root and stem]. Abstract:  OBJECTIVE: To study the anti-inflammatory and antibacterial effects of different processed products of Rosa laevigata root and stem.METHODS: Different processed products were obtained from Rosa laevigata root and stem by frying with vinegar,salt,honey and black bean juice. Their antibacterial effect was observed on bacteria such as Bacillus subtilis, Staphylococcus aureus and Escherichia coli; The mice auricle swelling method was used in anti-inflammatory experiment by using xylene. The mice cotton granuloma method was used to observe the chronic inflammatory effect.RESULTS: The antibacterial effects of processed products of Rosa laevigata root were better than that of the stem, especially the honey processed root. All processed products had no obvious effect on mouse auricular swelling. The raw root,salt processed stem, honey processed stem and honey processed root of Rosa laevigata had an inhibitory effect on cotton-pellet inducing mouse granuloma.CONCLUSION: The honey processed root of Rosa laevigata have significant antibacteral effect and anti-inflammatory effect on chronic infammation.

read more

21:57

Total saponins from Rosa laevigata can be applied as one effective candidate for the treatment of liver fibrosis. "IndyWatch Feed Health"

PMID:  Nutrients. 2015 Jun 15 ;7(6):4829-50. Epub 2015 Jun 15. PMID: 26083117 Abstract Title:  Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats. Abstract:  In this study, the protective effect of the total saponins from Rosa laevigata Michx (RLTS) against liver fibrosis induced by carbon tetrachloride (CCl4) in rats was evaluated. The results showed that RLTS significantly rehabilitated the levels of alanine aminotransferase, aspartate aminotransferase, malondialdehyde, glutathione, glutathione peroxidase, catalase, superoxide dismutase, hydroxyproline,-smooth muscle actin, collagen I, collagen III and fibronectin, which were confirmed using H&E, Sirius Red and Masson histopathological assays. Further research indicated that RLTS markedly reduced cytochrome P450 2E1 activity, attenuated oxidative stress, and suppressed inflammation. In addition, RLTS facilitated matrix degradation through down-regulation of matrix metalloproteinase2, matrix metalloproteinase 9 and metalloproteinases1, and exerted the anti-fibrotic effects through affecting transforming growth factor/Smad, focal adhesion kinase/phosphatidylinositol-3-kinase/amino kinase terminal/70-kDa ribosomal S6 Kinase (FAK-PI3K-Akt-p70(S6K)) and mitogen-activated protein kinase (MAPK) signaling pathways. Taken together, our data indicate that RLTS can be applied as one effective candidate for the treatment of liver fibrosis in the future.

read more

20:36

Breaking: CNN: Escape from the Mayo Clinic: Teen accuses world-famous hospital of medical kidnapping "IndyWatch Feed Health"

(Editors Note: PLEASE MAKE SURE TO SCROLL DOWN FOR THE CNN VIDEO.) We often have to report on sensitive issues like medical kidnapping however, we never thought wed be reporting that the well-known and much trusted Mayo Clinic in Minnesota would be the one responsible for kidnapping. And an adult! But thats exactly what happened to []

The post Breaking: CNN: Escape from the Mayo Clinic: Teen accuses world-famous hospital of medical kidnapping appeared first on Health Nut News.

20:09

Monsanto Found Guilty, Hit With $290 Million Cancer Liability Ruling in Roundup (Glyphosate) Herbicide Trial "IndyWatch Feed Health"

Source: Monsanto Found Guilty, Hit With $290 Million Cancer Liability Ruling in Roundup (Glyphosate) Herbicide Trial For more content like this visit REALfarmacy.com.

A San Francisco jury found Monsanto (now owned by Bayer) liable for the glyphosate-induced cancer of Dewayne Johnson, who is dying from non-Hodgkins lymphoma. Johnson sprayed glyphosate 20-30 times per year on public school grounds (near children, no less), and he was twice doused with glyphosate due to malfunctioning equipment. Monsanto which has been []

Source: Monsanto Found Guilty, Hit With $290 Million Cancer Liability Ruling in Roundup (Glyphosate) Herbicide Trial Learn more at REALfarmacy.com - Healthy News and Information.

18:58

NYT: New York moves to kick Spectrum out of state "IndyWatch Feed Health"

At the end of July, Gov. Andrew M. Cuomos administration (who is running for re-election against the Democratic candidate for governor, Cynthia Nixon and the Republican candidate, Marcus J. Molinaro) moved to ban Charter Communications from New York. The states Public Service Commission said the internet, television and phone behemoth had failed to comply with the []

The post NYT: New York moves to kick Spectrum out of state appeared first on Health Nut News.

18:48

New Source of Non-Cannabis, Non-Hemp Derived CBD Discovered "IndyWatch Feed Health"

By Alex Pietrowski

The explosion of interest in the medical benefits of cannabidiol (CBD) have followed the greater acceptance of cannabis and hemp. While the CBD industry grows at record pace, a vast amount of research is being conducted to identify the explicit health benefits of CBD.

Not commonly known is that CBDs are actually found in other plants and foods as well, leading to the possibility of medical-grade CBD being available to those in areas where CBD products derived from hemp and cannabis are still outlawed.

Researchers working for a San Francisco company, Peak Health Foundation, have recently discovered a new source of CBD not derived from cannabis or hemp, opening the door to more options for the development of CBD based tinctures and medicines. The plant is a variety of humulus, commonly known as hops, a grain commonly used in the production of beer and other alcoholic products, has been found to contain high levels of CBDs.

A San Francisco company, Peak Health Foundation, recently announced its first CBD product derived from a strain of humulus, more commonly known as hops. Not the ones used to make beer, but a strain discovered in India that contains no THC but high levels of CBD and is not derived from a plant that remains illegal.

Once a variety of hops was found in the wild with a reasonably high CBD content, Peak Health founder Bomi Joseph cross-bred the plants to create a new variety known as Kriya brand humulus. Joseph has patented the plant, which has a CBD concentration of ar...

18:05

Excess Vitamin D: Too Much Of A Good Thing? "IndyWatch Feed Health"

Excess Vitamin D: Too Much Of A Good Thing?By Rosanne Lindsay

reprised from February 2016

Vitamin D is known as the sunshine vitamin. This is because 90 percent of our D requirements naturally comes from the sun. Bioavailable vitamin D3 is created in the skin through the action of the suns UV-B rays on cholesterol (7-dehydroxycholesterol), as one of five forms.

Diet offers Vitamin D2 and D3 as the remaining ten percent (i.e., fish liver oils, fatty fish, egg yolks, and as fortified foods), though these forms are not biologically active. Vitamin D2, added to D-fortified foods, is produced synthetically by exposing the mold ergot (ergosterol) to ultraviolet light. This process was patented and licensed to pharmaceutical companies which is used as prescription vitamin D. D4 and D5 are synthetic analogues of D3 being tested in vitro for the treatment of cancer.

Vitamin Ds reputation as a potent cancer fighter is mainstream news. A lack of vitamin D is also reported to be behind increased rates of infections, heart disease, stroke, diabetes, osteoporosis, and autoimmune disorders. Models and studies have most of us convinced that excess vitamin D intake could reduce cancer deaths by 75 percent. Why else would the government add vitamin D2 to fortify food?  Meanwhile, as cancer rates rise, we are urged to cover up with sunscreen against the sun which nature intended as the truest source of vitamin D. Why the contradiction?[1]

17:39

Farmers and Environmentalists Call on DOJ to Block Bayer-Monsanto Toxic Mega Merger "IndyWatch Feed Health"

Farmers and Environmentalists Call on DOJ to Block Bayer-Monsanto Toxic Mega Merger

Farming, Food Safety, and Environmental Organizations Call on DOJ to Block Bayer-Monsanto Toxic Mega Merger

 Groups deliver 97,325 comments to DOJ opposing the merger

WASHINGTON A coalition of farming, consumer, and environmental groups delivered 97,325 public comments to the Department of Justice today, urging the agency to reject the Bayer (BAYN) and Monsanto (MON) merger. The agency closes its comment period today regarding its conditional approval of the merger.

The groups argue the merger threatens competition and innovation in our food system, compromises the future sustainability of agriculture, and harms farmers, agricultural workers and consumers. Regardless of the divestitures DOJ is requiring of Bayer, the merger could significantly reduce farmer seed choice, decrease quality and diversity of seeds, and increase prices.

...

17:24

Bayer Shares Plunge By 12.5 Billion After Monsanto Court Case "IndyWatch Feed Health"

Bayer stocks plunge following monsanto court case

Bayer AG, the German multinational pharmaceutical and life sciences company, is in panic after a huge share sell off on Monday morning, following the decision from a landmark legal case in San Francisco, which judged that the glyphosate-based weedkiller Roundup causes cancer. SEE: Jury Ruled Monsanto Liable In Case Of Man Dying Of Cancer After Using Weedkiller

The German companys newly acquired Monsanto subsidiary was left in shock Friday after they lost a landmark cancer trial in San Francisco and was ordered by the Judge to pay over USD 289 Million in total damages to the former school groundskeeper Dewayne Johnson, a California father who has non-Hodgkins lymphoma, which was caused by Monsantos glyphosate-based weedkiller Roundup.

Johnson, a father of three and former school groundskeeper, who doctors say may have just months to live, was the first person to take Monsanto to trial over allegations that the chemical sold under the Roundup brand causes cancer. About 4,000 other people in the U.S. claim in lawsuits they were sickened by Roundup.

Johnsons attorneys said he was diagnosed with non-Hodgkins Lymphoma after spraying the glyphosate-based Roundup weed killer for two and a half years.

Monsanto is responsible for Dewa...

15:58

Is Your Popcorn Laced With Hormone-Disrupting Chemicals? "IndyWatch Feed Health"

Is Your Popcorn Laced With Hormone-Disrupting Chemicals?

By Kathryn Alcantar & Jose Bravo, Buzzflash at Truthout

No one should be exposed to toxic chemicals in their food, particularly children. But thats exactly what the Center for Environmental Health found in tests of microwave popcorn bags sold in discount retailers. Communities of color and millions of poor Americans frequent these stores.

In fact, every single bag that was independently tested contained toxic per- or polyfluoroalkyl substances (PFASs) chemicals linked to developmental problems, hormone disruption, organ damage and more. These findings are particularly alarming for childrens health, as their bodies are still developing, making them more vulnerable to the effects of hormone disruptors.

In response to these findings, the Center released a video featuring the Oakland rapper Mystic and a local kindergarten class to educate families about dangerous toxic chemicals put in microwave popcorn bags. Filmed at Roses in Concrete Community School in East Oakland, the fun and engaging educational video also includes a supporting fact sheet that teaches families how to make their own safe, toxic-free microwave popcorn.

15:39

Lawmaker blocked anti-vaccine activists on Twitter. Now hes facing a lawsuit "IndyWatch Feed Health"

On July 27th, activists fighting for choice and safety in vaccines filed a suit in federal court against Sen. Richard Pan, D-Sacramento because he blocked them on Twitter, in violation of their First Amendment rights. Their lawsuit argues Pans Twitter account is a modern public forum because he is a government official. RELATED STORY: Questioning vaccines ought []

The post Lawmaker blocked anti-vaccine activists on Twitter. Now hes facing a lawsuit appeared first on Health Nut News.

14:56

New studies drop a bombshell on fish oil "IndyWatch Feed Health"

Omega-3 fats are essential polyunsaturated fats (PUFA) required for healthy digestion, muscle activity, blood clotting, visual acuity, memory and much more. Most omega-3s are considered essential fats as your body cannot make them. You have to get them from your diet. However, theres plenty of confusion when it comes to which omega-3 fats are required []

The post New studies drop a bombshell on fish oil appeared first on Health Nut News.

14:42

Doctor Describes Severe Reaction to Shingrix Vaccine with Refreshing Transparency "IndyWatch Feed Health"

By Kim Rossi Many years ago, I worked for a wonderful woman who became a mentor and second mother to me. She had a saying, "Don't punish progress." I think of her wise words every day. When one of my...

14:21

BREAKING: Bayer shares fall after Monsantos Roundup cancer trial "IndyWatch Feed Health"

Last week when I shared that Monsanto had been ordered to pay $289.2 million to former school groundskeeper Dewayne Johnson, currently dying of cancer (due to the Roundup he used) I suggested that perhaps this trial- the first of thousands was the first crack in their wall. And I may have been right. RELATED STORY: Bayer + Monsanto = []

The post BREAKING: Bayer shares fall after Monsantos Roundup cancer trial appeared first on Health Nut News.

14:11

Ireland Officials Say Fake News Is Spreading Measles "IndyWatch Feed Health"

Ireland is blaming fake news for its increase in measles cases. In 2017, there were a reported 25 measles cases. This year, Ireland has seen a rise to 66 cases. Measles outbreaks have effected France, Greece,...

The post Ireland Officials Say Fake News Is Spreading Measles appeared first on Vaxxter.

14:00

Are you liable for misconduct by scientific collaborators? What a recent court decision could mean for scientists "IndyWatch Feed Health"

Retraction Watch readers may have followed our coverage of the case of Christian Kreipke, a former Wayne State researcher who was recently barred from U.S. Federal funding for five years. That punishment followed years of allegations and court cases, along with half a dozen retractions. The case has been complicated, to say the least, and Continue reading Are you liable for misconduct by scientific collaborators? What a recent court decision could mean for scientists

13:57

Bayer + Monsanto = A match made in hell "IndyWatch Feed Health"

It should come as no shock that Bayer has decided to drop the Monsanto name as soon as their takeover is complete. After all, Monsanto is one of the most reviled companies in the world. However, dont let Bayer off the hook just yet. They also have an equally if not more atrocious history of death []

The post Bayer + Monsanto = A match made in hell appeared first on Health Nut News.

13:46

This boy has a full recovery from autism "IndyWatch Feed Health"

We fully understand that this doesnt happen for everyone and that many families are in agony every day watching their children struggle with Autism. However, we are so happy for this family and want to celebrate with them, and we believe other families would as well. RELATED STORY: If youre whitewashing autism, youre part of []

The post This boy has a full recovery from autism appeared first on Health Nut News.

12:02

New Documentary Indicts FDAs Regulation of Medical Devices "IndyWatch Feed Health"

From Forbes: A new Netflix documentary  The Bleeding Edge   highlights a wide range of systemic flaws in the FDAs regulation of medical devices. As always, the patient stories are truly heartbreaking (and often clinically gruesome), but what makes this documentary different is the sheer volume of clinical and legal testimony aimed so directly and forcefully at the FDA the one organization purpose-built to protect patients from a wide range of clinical risks  including those from medical device manufacturers.

Article 

12:01

Supportive Housing Reduces Homelessness, Health Care Costs "IndyWatch Feed Health"

From RAND Review: On any given night, tens of thousands of people sleep on the streets of Los Angeles, the nations capital of unsheltered homelessness.

But a recent RAND study found a reason for hope on those same streets. Los Angeles County has quietly succeeded in moving some of its most chronically homeless and vulnerable residents into permanent housing, with health care and social services. And its done it while saving taxpayers millions of dollars.

It makes a very compelling argument to say, Look, if we provide housing and support, we can actually save money, said Sarah Hunter, a senior behavioral scientist who led RANDs evaluation of the program and has spent years working with service providers on Los Angeless Skid Row.

Creating hurdles for people in need to receive housing is not the right approach, she said. There are better ways to meet the needs of some of the most vulnerable in our society.'

Article 

10:49

Boxers or Briefs? What's The Verdict on Loose or Tight-Fitting Underwear? "IndyWatch Feed Health"

One type of underwear exposes men to significantly higher sperm concentrations and total sperm counts when compared to others according to new research led by Harvard T.H. Chan School of Public Health. The findings of this study, conducted in the Fertility Clinic at Massachusetts General Hospital, suggest that certain styles of men's underwear may inhibit production of sperm.

07:12

These findings provide theoretic basis and experimental evidence for the application of Rosa laevigata in the treatment of diabetic cataract. "IndyWatch Feed Health"

PMID:  Int J Clin Exp Med. 2015 ;8(9):15759-65. Epub 2015 Sep 15. PMID: 26629073 Abstract Title:  Effects of Rosa laevigata Michx. extract on reactive oxygen species production and mitochondrial membrane potential in lens epithelial cells cultured under high glucose. Abstract:  This study was to investigate the effects of Rosa laevigata Michx. (RLM) extract on reactive oxygen species (ROS) production and mitochondrial membrane potential (MMP) in lens epithelial cells (LECs) cultured under high glucose. SRA01/04 cell models of diabetic cataract were established by high glucose culture, and these cells were administrated with RLM extract. Levels of ROS and MMP in SRA01/04 cells were detected with fluorescent probes. HO-1 expression level, Akt phosphorylation, and Nrf2 translocation were detected by Western blot. RLM treatment could exert protective effects on SRA01/04 cells under high glucose condition, decreasing the ROS production and elevating the MMP in these cells. Western blot analysis indicated that the expression level of HO-1 was significantly elevated in SRA01/04 cells after the RLM treatment. Moreover, when HO-1 was interfered with siRNA, the effects of RLM on the levels of ROS and MMP were diminished, indicating that HO-1 induction was necessary for the function of RLM. Furthermore, HO-1 inducing effects of RLM were mediated by the PI3K/Akt and Nrf2/ARE pathways. The effects would be abolished when either pathway was inhibited by pharmacological manipulation or siRNA silencing. RLM inhibits ROS production and elevates MMP, through the induction of HO-1 expression, in LECs under high glucose condition. The protective effects of RLM are mediated by the PI3K/Akt and Nrf2/ARE pathways. Our findings provide theoretic basis and experimental evidence for the application of RLM in the treatment of diabetic cataract.

read more

07:04

These findings confirmed the potent effects of total flavonoids from Rosa laevigata fruit against hepatic ischemia-reperfusion Injury "IndyWatch Feed Health"

PMID:  Nutrients. 2016 Jul 8 ;8(7). Epub 2016 Jul 8. PMID: 27399769 Abstract Title:  Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats. Abstract:  The effects of total flavonoids (TFs) from Rosa laevigata Michx fruit against liver damage and cerebral ischemia/reperfusion (I/R) injury have been reported, but its action on hepatic I/R injury remains unknown. In this work, the effects and possible mechanisms of TFs against hepatic I/R injury were examined using a 70% partial hepatic warm ischemia rat model. The results demonstrated TFs decreased serum aspartate transaminase (AST), alanine aminotransferase (ALT), myeloperoxidase (MPO), and lactate dehydrogenase (LDH) activities, improved liver histopathology and ultrastructure through hematoxylin-eosin (HE) staining and electron microscope observation. In addition, TFs significantly decreased malondialdehyde (MDA) and increased the levels of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), which indicated that TFs alleviated oxidative stress caused by I/R injury. RT-PCR results proved that TFs downregulated the gene levels of inflammatory factors including interleukin-1 beta (IL-1), interleukin-1 (IL-6), and tumor necrosis factor alpha (TNF-). Further research indicated that TF-induced hepatoprotection was completed through inhibiting TLR4/MyD88 and activating Sirt1/Nrf2 signaling pathways. Blockade of the TLR4 pathway by TFs inhibited NF-B and AP-1 transcriptional activities and inflammatory reaction. Activation of Sirt1/Nrf2 pathway by TFs increased the protein levels of HO-1 and GST to improve oxidative stress. Collectively, these findingsconfirmed the potent effects of TFs against hepatic I/R injury, which should be developed as a candidate for the preventionof this disease.

read more

07:00

Organic Egg Farmer Wages War on 'Health' Agency "IndyWatch Feed Health"

By Dr. Mercola

Jesse Laflamme, chief executive officer of America's No. 2 egg brand, Pete and Gerry's Organic Eggs, is asking tough questions about how the U.S. Food and Drug Administration (FDA) sets its food labeling rules.

After filing a 17-page citizen's petition with the FDA in April 2018, Laflamme took to his company's blog to make his point.1 Beneath photos of four food items, Laflamme posed this question: "Which of the following does the FDA consider 'healthy'?"

The three so-called healthy choices noted were fat-free chocolate pudding, low-fat toaster pastries and sugary cereal all of which the FDA considers to be good for you simply because they contain a few beneficial nutrients.

Surprisingly, the fourth food item featured organic eggs, a completely natural product does not meet the FDA's standards for application of the word "healthy."

Laflamme, who is passionate about saving his family's third-generation egg farm from bankruptcy, is urging the FDA to reconsider its labeling rules to allow egg companies like his to add the word "healthy" to their products as a means of educating consumers some of whom still believe eating eggs is bad for you.

If you think the FDA has your best interests in mind when it comes to food labeling, you may want to keep reading. The system regulating food labeling in the U.S. clearly is broken and it's clear eggs are a healthy food. Here's why.

The Puzzling Inconsistencies of Food Labeling

The basis of Laflamme's petition centers on the apparent inconsistencies noticeable in how the word "healthy" is applied to various foods under the umbrella of oversight provided by the FDA. About these inconsistencies, Inc. magazine asserts:2

"The FDA has strict rules governing food labels' nutrient content claims, but it also broadcasts puzzling inconsistencies. For example, the agency says an egg has too much fat, saturated fat and cholesterol to be considered healthy, but seemingly bad-for-you foods like low-fat pudding, which may be rich in potassium, calcium, iron and vitamin D are considered healthy."

The agency announced plans in September 2016 to change its rules related to what it deems health...

Ginger Is Great for Bad Breath "IndyWatch Feed Health"

By Dr. Mercola

Whether you're an enthusiast of Asian and East Indian cuisine or enjoy experimenting with different herbs and spices in the kitchen, it's likely you're familiar with the warming essence of ginger. From stir-fries to salad dressings, the flavor and fragrance of ginger is versatile and distinct.

And like so many plants, ginger is renowned for both traditional and modern medicinal remedies. An attractive perennial herb that produces a sideways-growing rhizome underground, ginger is the common name for the plant known as Zingiber officinale.

Some ginger species (and there are roughly 1,600 of them) produce beautiful tropical flowers, and most thrive in warm humid climates. Turmeric and cardamom are considered members of the ginger family, according to Healthy Food Tribe, which discloses how to keep the nubbly roots fresh:

"There are many tricks for keeping ginger fresh for longer in your kitchen. One way is to keep the ginger root in the freezer until it is ready to use. This is probably the easiest way to keep ginger fresh for a very long time You will often see pink pickled ginger in Japanese cuisine it makes for a fantastic palate cleanser when eaten between each course, making the flavor of each new dish more distinctive from the last."1

You can use a dehydrator to make ginger powder, which can be used in both smoothies and stir fries. To get the most of its complex, flavorful nuances, add ginger at the beginning of your cooking as well as toward the end, and peel it as little as possible for a deeper flavor profile.

Organic powdered ginger is an excellent alternative to using portions of ginger root, and can last up to a year when refrigerated. A number of studies reveal ginger as legendary throughout the world for thousands of years, and in many different capacities.

WebMD notes that this spice can stimulate saliva flow, settle an upset stomach, relieve nausea and diarrhea and prevent gas. One of the latest findings scientists have discovered2 is the chemical component in ginger responsible for eliminating bad breath.

How 6-Gingerol and Citric Acid Affect Saliva

The compound 6-gingerol, which enhances the mechanism that enables gastrointestinal transport (the time it takes for food to leave your stomach and travel through your intestines...

Are Many Fish Oils Synthetic? "IndyWatch Feed Health"

By Dr. Mercola

Omega-3 fats are essential polyunsaturated fats (PUFA) required for healthy digestion, muscle activity, blood clotting, visual acuity, memory and much more. Most omega-3s are considered "essential fats" as your body cannot make them. You have to get them from your diet. However, there's plenty of confusion when it comes to which omega-3 fats are required for optimal health.

You can obtain omega-3 fats from both plants and marine animals like fish and krill. However, these sources provide very different types of omega-3, and they are no way interchangeable.

Both plant- and animal-based omega-3 have their first double-bond in the third position hence the name "omega-3." However, the length of the carbon chain of each omega-3 fat makes a significant difference when it comes to bioavailability and biological effect.

Basic Differences Between Plant- and Marine Animal-Based Omega-3s

Animal-based omega-3 found in fatty fish, fish oil and krill oil primarily contain docosahexaenoic acid (DHA), a long-chained PUFA consisting of 22 carbons, and eicosapentaenoic acid (EPA), which has 20 carbons.

Plant-based omega-3 found in flaxseed, flaxseed oil, chia seeds, walnuts and leafy greens, for example contain alpha-linolenic acid (ALA), a shorter-chained PUFA consisting of 18 carbons. Plant-based omega-3 is completely devoid of DHA and EPA.

ALA is indeed a precursor to EPA and DHA, which is why some say you can simply consume plant-based omega-3s. However, an enzyme is required to convert the shorter 18 carbon ALA into long-chained omega-3, and in most people, this enzyme is simply unable to convert sufficient ALA to EPA, and even less DHA.

Importantly, short-chain fatty acids are used by your body as a source of energy, while the long-chain fatty acids, those with 20 and more carbons, especially EPA and DHA, are structural elements that actually make up your cells. This is perhaps the most significant difference between plant- and animal-based sources, and why they are not interchangeable from a health perspective.

As structural...

Weekly Health Quiz: Anniversary Week Recap "IndyWatch Feed Health"

1 Which of the following certifications offers the highest assurance of organic quality and regenerative standards?

  • All-natural certification
  • Fair trade certification
  • USDA 100% Organic certification
  • Biodynamic certification

    Certified biodynamic products adhere to regenerative standards that far surpass USDA 100% organic certification. Neither the "all-natural" label nor fair trade certification offer any guarantee of organic quality or regenerative methods. Learn more.

2 What percentage of cancer incidence can be prevented by raising vitamin D levels to 60 ng/mL?

  • 25 percent
  • 50 percent
  • 80 percent

    Brand-new data published by GrassrootsHealth shows 80 percent of cancer incidences could be prevented simply by raising vitamin D to 60 ng/mL from 20 ng/mL. Learn more.

  • 100 percent

3 Mercola.com has offered free health information to the public on the internet for how many years?

  • 12 years
  • 15 years
  • 21 years

    After starting a website to share the latest natural health developments in 1997, Mercola.com has been sharing information online for 21 years....

06:47

Protective effect of the total flavonoids from Rosa laevigata Michx fruit on renal ischemia-reperfusion injury. "IndyWatch Feed Health"

PMID:  Molecules. 2016 Jul 21 ;21(7). Epub 2016 Jul 21. PMID: 27455216 Abstract Title:  Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation. Abstract:  Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury (AKI). Our previous studies have shown that the total flavonoids (TFs) from Rosa laevigata Michx fruit has various activities, however, there were no papers reporting the role of the TFs against renal IRI. In the present work, a hypoxia/reoxygenation (H/R) model in NRK-52E cells and ischemia-reperfusion model in rats were used. The results showed that the TFs significantly attenuated cell injury and markedly decreased serum creatinine (Cr) and blood urea nitrogen (BUN) levels in rats. Further investigation revealed that the TFs markedly decreased the levels of malondialdehyde (MDA), superoxide dismutase (SOD), glutathione (GSH) and glutathione peroxidase (GSH-Px) and intracellular reactive oxygen species (ROS), up-regulated the levels of silent information regulator factor 2-related enzyme 1 (Sirt1), nuclear factor erythroid 2-related factor-2 (Nrf2) and heme oxygenase-1 (HO-1), down-regulated the levels of Kelch like ECH-associated protein-1 (Keap1) and the nuclear translocation of nuclear factor-Bp65 (NF-Bp65), and decreased the mRNA levels of interleukine-1 (IL-1), interleukin-6 (IL-6) and tumor necrosis factor- (TNF-). Furthermore, inhibiting Sirt1 by siRNA showed that the role of the natural product in protecting renal IRI was significantly attenuated, suggesting that the effect of the extract against renal IRI depended on Sirt1. Taken together, the TFs has significantly nephroprotective effect against IRI by affecting Sirt1/Nrf2/NF-B signaling pathway, which should be developed as a new therapeutic agent or food additives to treat acute kidney injury in the future.

read more

06:38

The neuroprotective and antioxidant profiles of selenium-containing polysaccharides from the fruit of Rosa laevigata. "IndyWatch Feed Health"

PMID:  Food Funct. 2018 Mar 1 ;9(3):1800-1808. Epub 2018 Mar 7. PMID: 29513319 Abstract Title:  The neuroprotective and antioxidant profiles of selenium-containing polysaccharides from the fruit of Rosa laevigata. Abstract:  Rosa laevigata fruit has been known as a functional foodstuff for a long time. Recently, increasing attention has been given to polysaccharides from R. laevigata fruit due to their numerous medicinal and nutritional properties. In this study, a rapid and effective approach for the extraction and separation of polysaccharides from the title fruit was developed using microwave-assisted aqueous two-phase extraction (MA-ATPE) with a PEG/ammonium sulfate system. After analysis of the response surface methodology (RSM) data based on a Box-Behnken design (BBD), a model was proposed and was found to predict an optimum yield value of 258.99 mg gwhich is in good agreement with the experimental value (258.59 mg g). Two selenium (Se)-containing polysaccharides, Se-RLFP-1 and Se-RLFP-2, were isolated from R. laevigata fruit. Their chemical structures were elucidated by acid hydrolysis, weight-average molecular mass and Se-content analysis, along with UV, FT-IR,H andC NMR spectroscopy. As a result, Se-RLFP-1 was found to be mainly composed of mannose, glucose, galactose and xylose in a molar ratio of 1.4:7.9:1.0:1.5, while Se-RLFP-2 was composed of mannose, rhamnose, glucose, galactose and xylose (12.6:1.0:38.3:5.6:19.6). Furthermore, the antioxidant properties of the polysaccharides were investigated on the basis of FRAP, ABTS and DPPH radical scavenging assays. The results showed that the two polysaccharides had a noticeable effect on the radical scavenging of ABTS and DPPH, especially at high concentrations. In addition, the neuroprotective effect of Se-RLFP-1 and Se-RLFP-2 against oxidative stress induced by HOin SH-SY5Y neuroblastoma cells was also investigated. In particular, Se-RLFP-1 exhibited obvious neuroprotective activity at a concentration of 100g mL.

read more

06:21

Dietary cocoa powder improves hyperlipidemia and reduces atherosclerosis. "IndyWatch Feed Health"

PMID:  Mediators Inflamm. 2016 ;2016:1937572. Epub 2016 Feb 15. PMID: 26980943 Abstract Title:  Dietary Cocoa Powder Improves Hyperlipidemia and Reduces Atherosclerosis in apoE Deficient Mice through the Inhibition of Hepatic Endoplasmic Reticulum Stress. Abstract:  Cocoa powder is rich in flavonoids, which have many beneficial effects on human health, including antioxidative and anti-inflammatory effects. The aim of our study was to investigate whether the intake of cocoa powder has any influence on hyperlipidemia and atherosclerosis and examine the underlying molecular mechanisms. We fed apoE knockout mice a Western diet supplemented with either 0.2% (low group) or 2% (high group) cocoa powder for 12 weeks. The groups fed dietary cocoa powder showed a significant reduction in both plasma cholesterol levels and aortic atherosclerosis compared to the control group. Analysis of mRNA profiling of aortic atherosclerotic lesions revealed that the expression of several genes related to apoptosis, lipid metabolism, and inflammation was significantly reduced, while the antiapoptotic gene Bcl2 was significantly increased in the cocoa powder group compared to the control. RT-PCR analysis along with Western blotting revealed that a diet containing cocoa powder inhibited the expression of hepatic endoplasmic reticulum stress. These data suggest that cocoa powder intake improves hyperlipidemia and atherosclerosis, and such beneficial effects are possibly mediated through the suppression of hepatic endoplasmic reticulum stress.

read more

06:08

Total flavonoids from Rosa laevigata fruit exhibited protective effect against lipopolysaccharide-induced liver injury. "IndyWatch Feed Health"

PMID:  Foods. 2018 Jun 8 ;7(6). Epub 2018 Jun 8. PMID: 29890650 Abstract Title:  Protection by the Total Flavonoids fromMichx Fruit against Lipopolysaccharide-Induced Liver Injury in Mice via Modulation of FXR Signaling. Abstract:  We previously reported the effects of the total flavonoids (TFs) fromMichx fruit against carbon tetrachloride-induced liver damage, non-alcoholic fatty liver disease, and liver ischemia-reperfusion injury. However, there have been no papers reporting the role ofTFs against lipopolysaccharide (LPS)-induced liver injury. In this paper, liver injury in mice was induced by LPS, andextract was intragastrically administered to the mice for 7 days. Biochemical parameters in serum and liver tissue were examined, and pathological changes were observed by transmission electron microscopy, hematoxylin and eosin (H&E) and Oil Red O staining. The results showed that the TFs markedly reduced serum ALT (alanine transferase), AST (aspartate transaminase), TG (total triglyceride), and TC (total cholesterol) levels and relative liver weights and improved liver pathological changes. In addition, the TFs markedly decreased tissue MDA (malondialdehyde) level and increased the levels of SOD (superoxide dismutase) and GSH-Px (glutathione peroxidase). A mechanistic study showed that the TFs significantly increased the expression levels of Nrf2 (nuclear erythroid factor2-related factor 2), HO-1 (heme oxygenase-1), NQO1 (NAD(P)H dehydrogenase (quinone 1), GCLC (glutamate-cysteine ligase catalytic subunit), and GCLM (glutamate-cysteine ligase regulatory subunit) and decreased Keap1 (Kelch-like ECH-associated protein 1) level by activating FXR (farnesoid X receptor) against oxidative stress. Furthermore, the TFs markedly suppressed the nuclear translocation of NF-B (nuclear factor-kappa B) and subsequently decreased the expression levels of IL (interleukin)-1, IL-6, HMGB-1 (high -mobility group box 1), and COX-2 (cyclooxygenase-2) by activating FXR and FOXO3a (forkhead box O3) against inflammation. Besides, the TFs obviously reduced the expression levels of SREBP-1c (sterol regulatory element-binding proteins-1c), ACC1 (acetyl-CoA carboxylase-1), FASN (fatty acid synthase), and SCD1 (stearoyl-coenzyme A desaturase 1), and improved CPT1 (carnitine palmitoyltransferase 1) level by activating FXR to regulate lipid metabolism. Our results suggest that TFs exhibited protective effect against LPS-induced liver injury by altering FXR-mediated oxidative stress, inflammation, and lipid metabolism, and should be developed as an effective food and healthcare product for the therapy of liver injury in the future.

read more

05:45

Induction of substantial myocardial regeneration by an active fraction of the Chinese herb Rosa laevigata Michx. "IndyWatch Feed Health"

PMID:  BMC Complement Altern Med. 2015 Oct 14 ;15:359. Epub 2015 Oct 14. PMID: 26467087 Abstract Title:  Induction of substantial myocardial regeneration by an active fraction of the Chinese herb Rosa laevigata Michx. Abstract:  BACKGROUND: The replacement of lost cardiac tissues by regenerated myocardium would be a therapeutic ideal for myocardial infarction. The objective of this study was therefore to evaluate the ability of an active fraction that was isolated from Rosa laevigata Michx in therapeutic cardiomyogenesis in a myocardial infarction rat model.METHODS: The myocardial infarction animal model was induced by the permanent ligation of the left anterior descending coronary artery in rats. The active fraction, which improves the survival rate and prevents ischemic reperfusion damage, was used to test the therapeutic effect of this fraction on myocardial infarction.RESULTS: The oral administration of the active fraction for 4 weeks could progressively restore the decreased cardiac function due to myocardial infarction. The significantly improved cardiac function was probably attributed to the active fraction-induced myocardial regeneration, which replaced the lost cardiac tissues in the myocardial infarction animals.CONCLUSIONS: The property of this active fraction appears to be entirely novel and may provide a potential therapeutic alternative for myocardial infarction.

read more

04:10

Extracts of Ilex paraguariensis protected splenocytes in vitro against chlorpyrifos. "IndyWatch Feed Health"

PMID:  Rev Fac Cien Med Univ Nac Cordoba. 2017 12 21 ;74(4):325-330. Epub 2017 Dec 21. PMID: 29902138 Abstract Title:  [In vitro Modulating Activity of aqueous extracts from American Plants on Chlorpyrifos-induced toxicity on Murine Splenocytes]. Abstract:  Background: Chlorpyrifos is an highly toxic pesticide, which can induce immunotoxicity with deleterious effects on health worldwide. On the other hand, American plants can provide derivatives with protective and immunostimulating activity. Thus, plant potential against chlorpyrifos should be assayed.Objective: To identify bioactive aqueous extracts from Lantana grisebachii (LG), Aspidosperma quebracho-blanco (AQ), Peumus boldus (PB), and Ilex paraguariensis (IP), against chlorpyrifos-induced toxicity on female Balb/c splenocytes. Material and method: Splenocytes were treated in vitro for 72 hours with 0-35g/mL of chlorpyrifos, 0-100 g/mL of each extract (LG, AQ, PB, IP), and 0-5 g/mL of concanavalin A. Then, cellular viability and death (resazurin-based and propidium iodide stainings), hydroperoxides, lipoperoxides (xylenol orange-based assay), ?-glutamyl transpeptidase activity (Szasz method)were measured and analyzed statistically.Results: Chlorpyrifos reduced splenocyte viability in a dose-dependent manner, which was counteracted by AQ and IP, which was less active in concanavalin A-responsive cells (p

read more

04:05

Yerba mate tea may help decrease oxidative stress and low-grade inflammation. "IndyWatch Feed Health"

PMID:  Int J Food Sci Nutr. 2018 Jul 2:1-10. Epub 2018 Jul 2. PMID: 29962254 Abstract Title:  Effect of mate tea (Ilex paraguariensis) on the expression of the leukocyte NADPH oxidase subunit p47and on circulating inflammatory cytokines in healthy men: a pilot study. Abstract:  Increased superoxide production by phagocytic NADPH oxidase has been associated with inflammatory conditions. Growing evidences suggest that dietary polyphenols may modulate the expression of NADPH oxidase subunits. Herein, we examined whether soluble mate tea (SMT) consumption - a polyphenol-rich beverage - affects the expression of the leukocyte NADPH oxidase protein p47and/or circulating biomarkers of inflammation and antioxidant biomarkers in humans. In a two-phase study, nine men were requested to drink water (control) for 8 d and then follow a second 8-d period drinking SMT. Blood samples were analysed for p47protein in CD16/CD14cells, interleukin (IL)-1 (IL-1), tumour necrosis factor-alpha (TNF-), IL-6, total phenols, and reduced and oxidised glutathione (GSH and GSSG, respectively) after each study phase. After SMT intake, CD16/CD14cells' p47protein and serum TNF- and IL-6 levels were significantly attenuated (P

read more

03:50

Analysis of radioprotection and antimutagenic effects of Ilex paraguariensis infusion and its component rutin. "IndyWatch Feed Health"

PMID:  Braz J Med Biol Res. 2018 Jul 16 ;51(9):e7404. Epub 2018 Jul 16. PMID: 30020319 Abstract Title:  Analysis of radioprotection and antimutagenic effects of Ilex paraguariensis infusion and its component rutin. Abstract:  DNA repair pathways, cell cycle checkpoints, and redox protection systems are essential factors for securing genomic stability. The aim of the present study was to analyze the effect of Ilex paraguariensis (Ip) infusion and one of its polyphenolic components rutin on cellular and molecular damage induced by ionizing radiation. Ip is a beverage drank by most inhabitants of Argentina, Paraguay, Southern Brazil, and Uruguay. The yeast Saccharomyces cerevisiae (SC7Klys 2-3) was used as the eukaryotic model. Exponentially growing cells were exposed to gamma rays () in the presence or absence of Ip or rutin. The concentrations used simulated those found in the habitual infusion. Surviving fractions, mutation frequency, and DNA double-strand breaks (DSB) were determined after treatments. A significant increase in surviving fractions after gamma irradiation was observed following combined exposure to +R, or +Ip. Upon these concomitant treatments, mutation and DSB frequency decreased significantly. In the mutant strain deficient in MEC1, a significant increase in sensitivity and a low effect of rutin on -induced chromosomal fragmentation was observed. Results were interpreted in the framework of a model of interaction between radiation-induced free radicals, DNA repair pathways, and checkpoint controls, where the DNA damage that induced activation of MEC1 nodal point of the network could be modulated by Ip components including rutin. Furthermore, ionizing radiation-induced redox cascades can be interrupted by rutin potential and other protectors contained in Ip.

read more

03:23

The intake of cacao products reduces hypertension and atherosclerosis. "IndyWatch Feed Health"

PMID:  Curr Pharm Des. 2018 ;24(2):191-202. PMID: 29119920 Abstract Title:  Polyphenols: Inflammation. Abstract:  BACKGROUND: Polyphenols widely distributed in plants, fruits and vegetables have received considerable attention on account of their physiological functions, including their antioxidant and anti-inflammatory properties. Some antioxidant components of cacao liquor prepared from fermented and roasted cacao beans, which is a major ingredient of cocoa and chocolate products, have been characterized as flavan-3-ols and procyanidin oligomers.METHODS: This review focuses on a specific group of (-)-epicatechins and their oligomers, the procyanidins, in cacao products. Dietary polyphenols in cacao products have been shown to reduce hypertension, reduce platelet aggregation, improve serum lipids, and lower the incidence of atherosclerosis in animal studies and clinical trials.CONCLUSION: The intake of cacao products reduces hypertension and atherosclerosis on account of their physiological functions as antioxidants and anti-inflammation agents, indicating the mechanisms of prevention of hypertension and atherosclerosis by polyphenols.

read more

02:48

Chocolate milk is a relatively unexplored recovery aid and warrants further attention. "IndyWatch Feed Health"

PMID:  J Sports Med Phys Fitness. 2015 Dec ;55(12):1438-44. Epub 2014 Oct 6. PMID: 25286886 Abstract Title:  The effectiveness of chocolate milk as a post-climbing recovery aid. Abstract:  AIM: Recovery is essential to effective performance in climbing competitions which often involve repeated bouts, and sport climbing where climbers may work a route over a number of days prior to a complete ascent.METHODS: This study employed a cross-over design to compare water with chocolate milk as recovery aids following an exhaustive bout of high intensity endurance climbing. Ten male climbers (age: 221 years; height: 178.57.9 cm; mass: 74.711.3 kg) climbed a Tredwall (Brewer Ledge M6) until volitional exhaustion. The participants consumed either water or chocolate milk 20 minutes after the climb and then again with their evening meal. The exercise protocol was repeated 24 hours after the original climb. The second condition was completed 7 days later. Workload indicators of heart rate, rate of perceived exertion (RPE), blood lactate and muscle soreness scores were recorded alongside climbing performance measures of duration and distance of the climb. A improved performance was foundafter the consumption of chocolate milk, with both a greater distance climbed (F(1,9)=11.704, P=0.008) and duration (F(1,9) =10.922, P=0.009), there were no differences in end of climb heart rate or RPE.RESULTS: Muscle soreness scores were lower three days after exercise following chocolate milk (t(8)=3.773, P=0.005). Chocolate milk as a recovery drink resulted in further sustained climbing, a decrease in muscle soreness, compared to water. It may be pertinent for climbers to consider its use as a recovery aid during repeated climbing bouts. Chocolate milk is a relatively unexplored recovery aid and warrants further attention.

read more

02:36

Chocolate could be a useful aid for recovery from exercise. "IndyWatch Feed Health"

PMID:  Eur J Clin Nutr. 2018 Jun 19. Epub 2018 Jun 19. PMID: 29921963 Abstract Title:  Chocolate milk for recovery from exercise: a systematic review and meta-analysis of controlled clinical trials. Abstract:  BACKGROUND/OBJECTIVES: Chocolate milk (CM) contains carbohydrates, proteins, and fat, as well as water and electrolytes, which may be ideal for post-exercise recovery. We systematically reviewed the evidence regarding the efficacy of CM compared to either water or other"sport drinks"on post-exercise recovery markers.SUBJECTS/METHODS: PubMed, Scopus, and Google scholar were explored up to April 2017 for controlled trials investigating the effect of CM on markers of recovery in trained athletes.RESULTS: Twelve studies were included in the systematic review (2, 9, and 1 with high, fair and low quality, respectively) and 11 had extractable data on at least one performance/recovery marker [7 on ratings of perceived exertion (RPE), 6 on time to exhaustion (TTE) and heart rate (HR), 4 on serum lactate, and serum creatine kinase (CK)]. The meta-analyses revealed that CM consumption had no effect on TTE, RPE, HR, serum lactate, and CK (P>0.05) compared to placebo or other sport drinks. Subgroup analysis revealed that TTE significantly increases after consumption of CM compared to placebo [mean difference (MD)=0.78min, 95% confidence interval (CI): 0.27, 1.29, P=0.003] and carbohydrate, protein, and fat-containing beverages (MD=6.13min, 95% CI: 0.11, 12.15, P=0.046). Furthermore, a significant attenuation on serum lactate was observed when CM was compared with placebo (MD=-1.2mmol/L, 95% CI: -2.06,-0.34, P=0.006).CONCLUSION: CM provides either similar or superior results when compared to placebo or other recovery drinks. Overall, the evidence is limited and high-quality clinical trials with more well-controlled methodology and larger sample sizes are warranted.

read more

Go Back:30 Days | 7 Days | 2 Days | 1 Day

IndyWatch Health Watch Feed Today.

Go Forward:1 Day | 2 Days | 7 Days | 30 Days

Sunday, 12 August

20:42

Monsanto Loses: Jury Awards Millions to Man Dying of Cancer Due to Herbicide Glyphosate Whats Next? "IndyWatch Feed Health"

monsanto-dewayne-Johnson

Dewayne Johnson with attorneys. Photo source.

by Brian Shilhavy
Editor, Health Impact News

This past Friday (August 10, 2018) a jury in California awarded Dewayne Johnson, a former school groundskeeper who is dying of cancer that he claims is the result of years of using the herbicide RoundUp which contains glyphosate, $39 million in damages, and another $250 million was levied against Monsanto for covering up the scientific evidence that glyphosate causes cancer.

Here is a video of the verdict being read in court:

This is the first legal blow against Monsanto for its herbicide product, which is the worlds most common herbicide, spread on crops all over the world.

In recent years, laboratory testing on urine and mothers breast milk shows that almost the entire worlds population contains glyphosate in their bodies.

Health Impact News has covered this story for years now, and we published an interview with Dr. Anthony Samsel back in 2015, when he was able to obtain formerly concealed documents from the Environmental Protection Agency (EPA) revealing the toxic nature and cancer risk of the ingredients in the herbicide RoundUp, but were concealed from the public due to trade secrets. See:

Glyphosate Causes Cancer: EPA Trade Secret Sealed Files Reveal Cancer Link Known Back in the 1970s

Much of the pre-trial legal maneuvering was centered around what evidence was going to be allowed in the trial. In the end, in spite of what appeared to be at some points a biased judge, enough evidence was presented to the jury to conclude Monsanto was guilty.

Learn more about the dangers of glyphosate.

Whats Next?

While Monsanto is obvious...

17:44

Vaccine Corruption Exposed To Washington State Board of Health "IndyWatch Feed Health"

By Catherine J. Frompovich

Bernadette Pajer, co-president of Informed Choice Washington, made the most exceptional presentation before the Washington State Board of Health regarding fully informed medical consent and choice, full-disclosure regarding vaccine science and ingredients, plus Big Pharmas apparently illegal tactics that deprive citizens of their inherent and indisputable rights to self-determination regarding their health, their childrens health and vaccines/vaccinations.

Ms. Pajers presentation needs to be studied, and even replicated, regarding what her group found out about the modus operandi of Big Pharma and vaccine manufacturers to deny personal health rights and the obvious collusion that goes on between dozens of groups, if not hundreds, and that Big Pharma foots the bill.

If that is not collusion and something subject to legal action under the RICO and Sherman Anti-Trust laws of the United States, I dont know what is.

Brave Mom Exposes Vaccine Corruption To Washington State Board of Health
5:28 minutes

...

16:53

Deadly Serious: Talking Openly About Suicide "IndyWatch Feed Health"

Editors note: A list of warmlines, peer support groups, discussions about suicide and other resources can be found at the bottom of this post. 

Not long ago, a friend of mine called the National Suicide Hotline. He was having a hard day and needed his distress to be heard. He barely got started talking before the operator interrupted him. It was the standard suicide assessment:

  • Are you suicidal?
  • Do you have a plan?
  • Do you have the means?
  • Have you set a date?

They also made clear that if he answered the questions a certain way, the 911 van would be dispatched to his residence forthwith.

Frankly, this is why I would never refer someone I loved to a suicide hotline. If I had any doubt about killing myself before calling, this kind of response would pretty much seal the deal. Theres the basic human insult of getting asked impersonal, pro forma questions like these in my darkest hour at my time of greatest need. Heap on top of that the public humiliation of getting hauled off to the nut ward by 911, flashing lights and all, for my neighborhood to see, on the worst day of my life.

Yes, not all hotlines and hotline operators are like this, but enough of them are that I, personally, wouldnt risk it. Suffice it to say:  If I had any shred of a doubt remaining  or perhaps a threadbare hope in the good of humanity  this wholesale warping of the nature of human aid, sponsored by my government, funded with my tax dollars, would cut the cord once and for all between me and any lingering desire to live.

So whats the solution.? After all, this crisis is real. The pain is real. The despair is real. The deaths are real. Tons and tons of Americans  as well as others worldwide  feel hopeless, worthless, disconnected as if we have nothing of value to offer and our lives have only become burdens to those we love.

This really is life and death. So none of us can afford to stick our heads in the sand and pretend anymore: It isnt me. It isnt someone I love. It isnt happening

At the same time, the helplessness and confusion about what to do about it are also real.

And thats exactly why peer relationships and peer-developed modalities can be so helpful. Many, many of us have been there. Many, many of us know what it is like. Many, many of us are still alive to talk about it. We know what we tried, what worked for us and what didnt. We know what ways of relating gave us hope and helped us to continue on.

Just as important: we know what not to do, what devastated us, wasted precious resources or made life altogether unbearable. As a result of these experiences, weve developed countless...

12:00

Vaccine Choice - Respect the Answer "IndyWatch Feed Health"

By Cathy Jameson For years, Ronans siblings have been praying for a miracle. On any given day, they share one of a few consistent requests during our familys evening prayer time. They ask God for Ronan to be able to...

11:48

Fluoride: A review of use and effects on health. "IndyWatch Feed Health"

Excerpts:

4.6 European directive for the use of fluorides

The European Academy of Paediatric Dentistry (EAPD) recommends to everybody, including pregnant women, the preventive use of fluoride toothpaste as a primary preventive measure against caries (7). The most effective way to prevent dental caries is tooth brushing twice a day. Children should only spit out the toothpaste and not rinse with water afterwards.

Parents should start brushing childrens teeth with fluoride toothpaste as soon as the first tooth erupts in the concentration and quantity recommended by the EAPD (Table 2) (7). Parents should use the recommended amount of toothpaste and assist or supervise their children with tooth brushing at least up to the age of 7.

Table 2

Recommended use of fluoride toothpaste for children. Source: European Academy of Paediatric Dentistry (EAPD), 2009.

An external file that holds a picture, illustration, etc. Object name is MSM-28-133-g002.jpg

07:00

Mercola Recipe Section Has Something for Everyone "IndyWatch Feed Health"

By Dr. Mercola

Many struggle with obesity and a variety of chronic diseases. Although your food choices affect your health and how you feel today, tomorrow and in the future, rapid growth in the processed food industry has triggered an avalanche of weight gain, inflammation and chronic disease.

It might be difficult to imagine you could find nutritious and delicious meals that are easy to fix and satisfying to eat, but this is exactly what youll find in the Recipe section.

Although eating right is not an overnight fix for chronic health conditions, it is one of the most effective steps to help you achieve health independence. We have a diverse collection of mouth-watering and good-for-you recipes based on my optimized nutrition plan.

In the recipe section you'll find high-fiber meals to help control your blood sugar, support your immune system function, boost your weight loss and lower your risk of disease.

Satisfying salad recipes are a no-brainer as there are many choices to help you combine some of your favorite vegetables into one meal. Well give you suggestions to find organically grown fruits and vegetables and a variety of homemade salad dressing recipes so you control the types of seasonings and oils going into your blend.

Red meat is a main ingredient in dishes found around the globe because of its taste and versatility. What sets these recipes apart are the use of meat from organic, grass fed livestock combined with creative seasoning to make your whole family's mouths water.

Healthy Desserts? Yes!

If you thought you had to give up cookies or cocoa, think again. Our Nutty No-Bake Keto Cookie recipe and Creamy Keto Hot Cocoa recipe are a combination sure to satisfy your sweet tooth without the carbohydrates.

The Nutty No-Bake Keto Cookies take just 20 minutes to prepare, and even less time to eat. Instead of loading up on processed sweets and pastries, why not make your own using a recipe that doesn't even require your oven? The combination of macadamia nuts, pecans and grass fed butter make these cookies melt in your mouth.

Nutty No-Bake Keto Cookies Nutty No-Bake Keto Cookies

Chocolate is a favorite treat for many. Cocoa is highly versatile and refers to roasted cacao or cocoa beans ground into a powder where most of...

Updates on the Fight for Mercury-Free Dentistry "IndyWatch Feed Health"

By Dr. Mercola

In this interview, Charlie Brown, founder of Consumers for Dental Choice, provides us with an update to the global mercury-free dentistry campaign you've so generously helped us support through the past eight years.

We are now incredibly close to the ultimate finish line, thanks to Brown's persistent and dedicated efforts and your unrelenting financial support. I want to extend a personal thank you to all who have contributed to this mission in the past, and are considering doing so now.

"We've been a great team since 2010," Brown says. "It's been fantastic. Without Mercola.com, we could not have built this world juggernaut, because that's where we are now in terms of our progress."

European Union Bans Dental Amalgam for Most Vulnerable Populations

Topping our list of good news: Consumers for Dental Choice has successfully facilitated a total ban on dental amalgam for children under 15 and pregnant and nursing women within the European Union (EU), effective July 1, 2018 a victory that will positively affect half a billion people in 28 countries.

Edo, Nigeria, has also followed suit, as have the Bangladesh Dental Society (BDS), the Bangladesh Civil Society and the Vietnam Dental Society. In 2020, the EU will decide whether to take it a step further and phase out amalgam for all individuals across Europe. "Believe me, we're going to be there. When that question comes, there's only going to be one answer," Brown says.

donate today

>>>>> Click Here <<<<<</strong>

Checks can also be mailed to:

Consumers for Dental Choice
316 F St., N.E., Suite 210
Washington DC 20002

Chicago Declaration to End Dental Industry Mercury Use

In the U.S., Chicago has become a leading torch-bearer for mercury-free dentistry. "We decided Chicago was the right place. It's the city where so many ideas assembled," Brown says.

They began by getting a number of groups involved, including Sierra Club, Greenpeace, the Environmental Working Group, the Organic and Natural Health Association, the Learning Disabilities Association of America, Health Care Without Harm, the International Indian Treaty Council and the Mercury Policy Project.

Al...

Saturday, 11 August

23:42

Low Prenatal Exposures to Fluoride: Are There Neurotoxic Risks for Children? "IndyWatch Feed Health"

As a trace element, fluoride can help ward off dental cavities. Exceptionally high pre- and postnatal exposures, as seen in populations whose drinking water supplies are contaminated by natural fluoride sources, have been implicated in a number of adverse health effects.1,2,3,4 However, less is known about fluorides neurotoxic risks at lower levels of exposure. A new study in Environmental Health Perspectives examines risks of exposure to prenatal fluoride at concentrations typical of the general population.5

In many countries, small amounts of fluoride are added to drinking water, salt, or milk to reduce the incidence of tooth decay.6,7,8 The U.S. Public Health Service recommends an optimal level of 0.7 mg/L fluoride in drinking water for caries prevention.2 Fluoride can also occur naturally in water, with concentrations exceeding 4.0 mg/L in some areas of the United States1; this is the maximum contaminant level for fluoride set by the U.S. Environmental Protection Agency.6

There is some debate regarding whether fluoridation is still needed for drinking water. Fluoridation of public water supplies was started in 1945 in the United States as a preventive measure to reduce the incidence of tooth decay.9 Most of the evidence for the benefits of fluoridation was collected prior to 1975, before widespread use of fluoride toothpastes and dental treatments1,9 and before modern assessments of dietary sources of fluoride....

23:14

Riboflavin supplementation before and during prolonged running might reduce muscle pain and soreness. "IndyWatch Feed Health"

PMID:  Sports Med Open. 2017 Dec ;3(1):14. Epub 2017 Mar 28. PMID: 28349501 Abstract Title:  A Placebo-Controlled Trial of Riboflavin for Enhancement of Ultramarathon Recovery. Abstract:  BACKGROUND: Riboflavin is known to protect tissue from oxidative damage but, to our knowledge, has not been explored as a means to control exercise-related muscle soreness. This study investigated whether acute ingestion of riboflavin reduces muscle pain and soreness during and after completion of a 161-km ultramarathon and improves functional recovery after the event.METHODS: In this double-blind, placebo-controlled trial, participants of the 2016 161-km Western States Endurance Run were assigned to receive a riboflavin or placebo capsule shortly before the race start and when reaching 90 km. Capsules contained either 100 mg of riboflavin or 95 mg of maltodextrin and 5 mg of 10% -carotene. Subjects provided muscle pain and soreness ratings before, during, and immediately after the race and for the 10 subsequent days. Subjects also completed 400-m runs at maximum speed on days3, 5, and 10 after the race.RESULTS: For the 32 (18 in the riboflavin group, 14 in the placebo group) race finishers completing the study, muscle pain and soreness ratings during and immediately after the race were found to be significantly lower (p=.043) for the riboflavin group. Analysis of the 400-m run times also showed significantly faster (p

read more

23:10

There is potential application of vitamin B2 enrichment for attenuation of insulin resistance and metabolic syndrome development. "IndyWatch Feed Health"

PMID:  Molecules. 2016 Dec 15 ;21(12). Epub 2016 Dec 15. PMID: 27983705 Abstract Title:  Riboflavin Reduces Pro-Inflammatory Activation of Adipocyte-Macrophage Co-culture. Potential Application of Vitamin B2 Enrichment for Attenuation of Insulin Resistance and Metabolic Syndrome Development. Abstract:  Due to the progressive increase in the incidence of obese and overweight individuals, cardiometabolic syndrome has become a worldwide pandemic in recent years. Given the immunomodulatory properties of riboflavin, the current study was performed to investigate the potency of riboflavin in reducing obesity-related inflammation, which is the main cause of insulin resistance, diabetes mellitus 2 or arteriosclerosis. We determined whether pretreatment with a low dose of riboflavin (10.4-1000 nM) affected the pro-inflammatory activity of adipocyte-macrophage co-culture (3T3 L1-RAW 264.7) following lipopolysaccharide stimulation (LPS; 100 ng/mL) which mimics obesity-related inflammation. The apoptosis of adipocytes and macrophages as well as tumor necrosis factor-alpha (TNF-), interleukin 6 (IL-6), interleukin 1beta (IL-1), monocyte chemotactic protein 1 (MCP-1), high-mobility group box 1 (HMGB1), transforming growth factor-beta 1 (TGF), interleukin 10 (IL-10), inducible nitric oxide synthase (iNOS), nitric oxide (NO), matrix metalloproteinase 9 (MMP-9), tissue inhibitor of metalloproteinases-1 (TIMP-1) expression and release, macrophage migration and adipokines (adiponectin and leptin) were determined. Our results indicated an efficient reduction in pro-inflammatory factors (TNF, IL-6, MCP-1, HMGB1) upon culture with riboflavin supplementation (500-1000nM), accompanied by elevation in anti-inflammatory adiponectin and IL-10. Moreover, macrophage migration was reduced by the attenuation of chemotactic MCP-1 release and degradation of the extracellular matrix by MMP-9. In conclusion, riboflavin effectively inhibits the pro-inflammatory activity of adipocyte and macrophage co-cultures, and therefore we can assume that its supplementation may reduce the likelihood of conditions associated with the mild inflammation linked to obesity.

read more

22:55

These results observed a statistically-significant better survival for ACAD9 deficient patients treated with riboflavin. "IndyWatch Feed Health"

PMID:  Orphanet J Rare Dis. 2018 Jul 19 ;13(1):120. Epub 2018 Jul 19. PMID: 30025539 Abstract Title:  Clinical, biochemical and genetic spectrum of 70 patients with ACAD9 deficiency: is riboflavin supplementation effective? Abstract:  BACKGROUND: Mitochondrial acyl-CoA dehydrogenase family member 9 (ACAD9) is essential for the assembly of mitochondrial respiratory chain complex I. Disease causing biallelic variants in ACAD9 have been reported in individuals presenting with lactic acidosis and cardiomyopathy.RESULTS: We describe the genetic, clinical and biochemical findings in a cohort of 70 patients, of whom 29 previously unpublished. We found 34 known and 18 previously unreported variants in ACAD9. No patients harbored biallelic loss of function mutations, indicating that this combination is unlikely to be compatible with life. Causal pathogenic variants were distributed throughout the entire gene, and there was no obvious genotype-phenotype correlation. Most of the patients presented in the first year of life. For this subgroup the survival was poor (50% not surviving the first 2 years) comparing to patients with a later presentation (more than 90% surviving 10 years). The most common clinical findings were cardiomyopathy (85%), muscular weakness (75%) and exercise intolerance (72%). Interestingly, severe intellectual deficits were only reported in one patient and severe developmental delays in four patients. More than 70% of the patients were able to perform the same activities of daily living when compared to peers.CONCLUSIONS: Our data show that riboflavin treatment improves complex I activity in the majority of patient-derived fibroblasts tested. This effect was also reported for most of the treated patients and is mirrored in the survival data. In the patient group with disease-onset below 1 year of age, we observed a statistically-significant better survival for patients treated with riboflavin.

read more

22:42

Supplementation with B vitamins could reduce body weight gain and plasma levels of lipids by improving energy metabolism-related enzyme activities. "IndyWatch Feed Health"

PMID:  Curr Med Sci. 2018 Feb ;38(1):174-183. Epub 2018 Mar 15. PMID: 30074168 Abstract Title:  B Vitamins Can Reduce Body Weight Gain by Increasing Metabolism-related Enzyme Activities in Rats Fed on a High-Fat Diet. Abstract:  B vitamins are enzyme cofactors that play an important role in energy metabolism. The aim of this study was to elucidate whether B vitamin administration can reduce body weight (BW) gain by improving energy metabolism-related enzyme activities in rats fed on a highfat diet. Fifty rats were randomly assigned to one of the following five groups: control group (C), including rats fed on standard rat chow; four treatment groups (HO, HI, H2, and H3), in which rats were fed on a high-fat diet. Rats in the HI group were treated daily with 100 mg/kg BW thiamine (VB1), 100 mg/kg BW riboflavin (VB2), and 250 mg/kg BW niacin (VPP); rats in the H2 group were treated daily with 100 mg/kg BW pyridoxine (VB6), 100 mg/kg BW cobalamin (VB12), and 5 mg/kg BW folate (FA); and rats in the H3 group were treated daily with all of the B vitamins administered to the HI and H2 groups. After 12 weeks, the BW gains from the initial value were 154.558.4 g and 159.153.0 g in the HI and C groups, respectively, which were significantly less than the changes in the HO group (285.214.8 g, P

read more

22:28

Myopia prevention and outdoor light intensity in a school-based cluster randomized trial. "IndyWatch Feed Health"

PMID:  Ophthalmology. 2018 Aug ;125(8):1239-1250. Epub 2018 Jan 19. PMID: 29371008 Abstract Title:  Myopia Prevention and Outdoor Light Intensity in a School-Based Cluster Randomized Trial. Abstract:  PURPOSE: To investigate the effectiveness of a school-based program promoting outdoor activities in Taiwan for myopia prevention and to identify protective light intensities.DESIGN: Multi-area, cluster-randomized intervention controlled trial.PARTICIPANTS: A total 693 grade 1 schoolchildren in 16 schools participated. Two hundred sixty-seven schoolchildren were in the intervention group and 426 were in the control group.METHODS: Initially, 24 schools were randomized into the intervention and control groups, but 5 and 3 schools in the intervention and control groups, respectively, withdrew before enrollment. A school-based Recess Outside Classroom Trial was implemented in the intervention group, in which schoolchildren were encouraged to go outdoors for up to 11 hours weekly. Data collection included eye examinations, cycloplegic refraction, noncontact axial length measurements, light meter recorders, diary logs, and questionnaires.MAIN OUTCOME MEASURES: Change in spherical equivalent and axial length after 1 year and the intensity and duration of outdoor light exposures.RESULTS: The intervention group showed significantly less myopic shift and axial elongation compared with the control group (0.35 diopter [D] vs. 0.47 D; 0.28 vs. 0.33 mm; P = 0.002 and P = 0.003) and a 54% lower risk of rapid myopia progression (odds ratio, 0.46; 95% confidence interval [CI], 0.28-0.77; P = 0.003). The myopic protective effects were significant in both nonmyopic and myopic children compared with controls. Regarding spending outdoor time of at least11 hours weekly with exposure to 1000 lux or more of light, the intervention group had significantly more participants compared with the control group (49.79% vs. 22.73%; P

read more

22:27

Occupational fluoride exposure. "IndyWatch Feed Health"

Understandably, it is not uncommon to find reference to arthritic changes, if for no other reason than the difficulty of distinguishing them from certain fluoride effects on bone.

Data are available from a single epidemiological study of gynecologic problems in female workers in a superphosphate manufacturing plant (Kuznetsova, 1969)[ref.99]. The exposed group comprised 302 women mostly 20-40 years old and the control group 309 office employees and housewives not exposed to F. Dust concentrations in the superphosphate plant ranged from 5 to 57 mg/m3; F concentrations ranged from about 0.3 to 2.8 mg/m3. Irregularities of menstruation were considerable more frequent (five or six times) in the workers; the frequency increased with dustiness, not with age, but markedly (two times) with employment over six years. Inflammation of the uterus, cervix and vagina occurred four times as frequently in workers, mostly in women exposed to plain and granulated superphosphate.

No differences were noted between exposed and control groups in the numbers or the courses of pregnancies, miscarriages, and births. During pregnancy, the plant workers more frequently showed (a) toxicosis with hypotension and threatened abortion, and (b) untimely discharge of amniotic fluid and weakness of birth activity [Kuznetsova LS s, Gig Tr i Prof Zabol 13:21-5,1969]. Additional epidemiological studies are needed.

22:24

Violet light exposure can be a preventive strategy against myopia progression. "IndyWatch Feed Health"

PMID:  EBioMedicine. 2017 Feb ;15:210-219. Epub 2016 Dec 16. PMID: 28063778 Abstract Title:  Violet Light Exposure Can Be a Preventive Strategy Against Myopia Progression. Abstract:  Prevalence of myopia is increasing worldwide. Outdoor activity is one of the most important environmental factors for myopia control. Here we show that violet light (VL, 360-400nm wavelength) suppresses myopia progression. First, we confirmed that VL suppressed the axial length (AL) elongation in the chick myopia model. Expression microarray analyses revealed that myopia suppressive gene EGR1 was upregulated by VL exposure. VL exposure induced significantly higher upregulation of EGR1 in chick chorioretinal tissues than blue light under the same conditions. Next, we conducted clinical research retrospectively to compare the AL elongation among myopic children who wore eyeglasses (VL blocked) and two types of contact lenses (partially VL blocked and VL transmitting). The data showed the VL transmitting contact lenses suppressed myopia progression most. These results suggest that VL is one of the important outdoor environmental factors for myopia control. Since VL is apt to be excluded from our modern society due to the excessive UV protection, VL exposure can be a preventive strategy against myopia progression.

read more

22:20

This paper summarizes the progress in research of the association between sunlight exposure and myopia in children. "IndyWatch Feed Health"

PMID:  Zhonghua Liu Xing Bing Xue Za Zhi. 2016 Nov 10 ;37(11):1555-1560. PMID: 28057151 Abstract Title:  [Progress in research of association between myopia and sunlight exposure in children]. Abstract:  Myopia has become a major health problem on global scale due to its increasing high prevalence in the past few decades and gradual younger onset age. Accumulated epidemiological surveys have shown that decreased time of exposure to sunlight would be an inducement for the development of myopia. Increasing time spent outdoors and exposure to sunlight might be the most cost-effective and effective measure for children to prevent myopia. This paper summarizes the progress in research of the association between sunlight exposure and myopia in children and its mechanisms to provide new clues for the research on myopia prevention and control.

read more

22:08

Riboflavin has demonstrated efficacy in the reduction of adult patient's migraine headache frequency. "IndyWatch Feed Health"

PMID:  J Clin Pharm Ther. 2017 Aug ;42(4):394-403. Epub 2017 May 8. PMID: 28485121 Abstract Title:  Prophylaxis of migraine headaches with riboflavin: A systematic review. Abstract:  WHAT IS KNOWN AND OBJECTIVE: Migraine headache is a relatively common, debilitating condition that costs our healthcare system over 78 billion dollars per year. Riboflavin has been advocated as a safe, effective prophylactic therapy for the prevention of migraines. The purpose of this study was to provide a systematic review of the current role of riboflavin in the prophylaxis of migraine headache.METHODS: A MEDLINE literature search inclusive of the dates 1966-2016 was performed using the search terms: riboflavin and migraine disorders. Excerpta Medica was searched from 1980 to 2016 using the search terms: riboflavin and migraine. Additionally, Web of Science was searched using the terms riboflavin and migraine inclusive of 1945-2016. Bibliographies of all relevant papers were reviewed for additional citations. We utilized the PRISMA guidelines to select English language, human, clinical trials of riboflavin as a single entity or in combination, review articles, and supporting pharmacokinetic and pharmacogenomic data assessing the efficacy and mechanism of riboflavin therapy in the prophylactic treatment of migraine headache.RESULTS AND DISCUSSION: A total of 11 clinical trials reveal a mixed effect of riboflavin in the prophylaxis of migraine headache. Five clinical trials show a consistent positive therapeutic effect in adults; four clinical trials show a mixed effect in paediatric and adolescent patients, and two clinical trials of combination therapy have not shown benefit. Adverse reactions with riboflavin have generally been mild.WHAT IS NEW AND CONCLUSION: Riboflavin is well tolerated, inexpensive and has demonstrated efficacy in the reduction of adult patient's migraine headache frequency. Additional data are needed, however, to resolve questions involving pharmacokinetic issues and pharmacogenomic implications of therapy.

read more

IndyWatch Health Watch Feed Archiver

Go Back:30 Days | 7 Days | 2 Days | 1 Day

IndyWatch Health Watch Feed Today.

Go Forward:1 Day | 2 Days | 7 Days | 30 Days

IndyWatch Health Watch Feed was generated at Community Resources IndyWatch.

Resource generated at IndyWatch using aliasfeed and rawdog